A survey of the year 2002 commercial optical biosensor literature

The Cluster Glycoside Effect

2002 • 1,482 citations

Biomedical surface science: Foundations to frontiers

2002 • 1,301 citations

Killing activity of neutrophils is mediated through activation of proteases by K+ flux

2002 • 1,141 citations

Global Conformational Rearrangements in Integrin Extracellular Domains in Outside-In and Inside-Out Signaling

2002 • 1,134 citations

Biological surface science

2002 • 1,055 citations

Optical biosensors in drug discovery

2002 • 953 citations

Inflammatory Mediators and the Failing Heart

2002 • 938 citations

Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-β

2002 • 866 citations

Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition

2002 • 787 citations

Molecular Architecture of SMC Proteins and the Yeast Cohesin Complex

2002 • 718 citations

Self-assembled monolayers as a tunable platform for biosensor applications

2002 • 715 citations

Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes

2002 • 692 citations

Peptide chips for the quantitative evaluation of protein kinase activity

2002 • 691 citations

Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL

2002 • 689 citations

The Interaction Properties of Costimulatory Molecules Revisited

2002 • 640 citations

TL1A Is a TNF-like Ligand for DR3 and TR6/DcR3 and Functions as a T Cell Costimulator

2002 • 602 citations

Single‐domain antibody fragments with high conformational stability

2002 • 586 citations

Review of the use of biosensors as analytical tools in the food and drink industries

2002 • 567 citations

Structures of Glycoprotein Ibα and Its Complex with von Willebrand Factor A1 Domain

2002 • 550 citations

Carbohydrate Arrays for the Evaluation of Protein Binding and Enzymatic Modification

2002 • 490 citations

Albumin Binding as a General Strategy for Improving the Pharmacokinetics of Proteins

2002 • 468 citations

P-Rex1, a PtdIns(3,4,5)P3- and Gβγ-Regulated Guanine-Nucleotide Exchange Factor for Rac

2002 • 460 citations

Multiple Roles of Arabidopsis VRN1 in Vernalization and Flowering Time Control

2002 • 454 citations

Selectins: lectins that initiate cell adhesion under flow

2002 • 409 citations

The Phosphotyrosine Binding-like Domain of Talin Activates Integrins

2002 • 400 citations

Receptor-mediated Immunoglobulin G Transport Across Mucosal Barriers in Adult Life

2002 • 381 citations

Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays

2002 • 366 citations

Human Cytomegalovirus Binding to DC-SIGN Is Required for Dendritic Cell Infection and Target Cell trans-Infection

2002 • 358 citations

C‐terminal domains of Listeria monocytogenes bacteriophage murein hydrolases determine specific recognition and high‐affinity binding to bacterial cell wall carbohydrates

2002 • 348 citations

Selective immobilization of proteins to self-assembled monolayers presenting active site-directed capture ligands

2002 • 338 citations

Increasing the Affinity of a Human IgG1 for the Neonatal Fc Receptor: Biological Consequences

2002 • 329 citations

Potent neutralization of botulinum neurotoxin by recombinant oligoclonal antibody

2002 • 321 citations

CD44 directs membrane-type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin-like domain

2002 • 319 citations

Specific Molecular Interactions of Oversulfated Chondroitin Sulfate E with Various Heparin-binding Growth Factors

2002 • 319 citations

A perspective on protein microarrays

2002 • 314 citations

Binding of the PX domain of p47phox to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction

2002 • 308 citations

Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2

2002 • 306 citations

(Bio)sensors for measurement of analytes implicated in food safety: a review

2002 • 300 citations

Protein Adsorption on Supported Phospholipid Bilayers

2002 • 297 citations

Structure and functional interactions of the Tsg101 UEV domain

2002 • 294 citations

Identification of ARAP3, a Novel PI3K Effector Regulating Both Arf and Rho GTPases, by Selective Capture on Phosphoinositide Affinity Matrices

2002 • 293 citations

Molecular Structure of the GARP Family of Plant Myb-Related DNA Binding Motifs of the Arabidopsis Response Regulators

2002 • 292 citations

Two-step binding mechanism for T-cell receptor recognition of peptide–MHC

2002 • 279 citations

Protection against anthrax toxin by recombinant antibody fragments correlates with antigen affinity

2002 • 278 citations

A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation

2002 • 273 citations

Cutting Edge: Murine UL16-Binding Protein-Like Transcript 1: A Newly Described Transcript Encoding a High-Affinity Ligand for Murine NKG2D

2002 • 271 citations

A peptide that binds and stabilizes p53 core domain: Chaperone strategy for rescue of oncogenic mutants

2002 • 267 citations

Conjugates of antisense oligonucleotides with the Tat and antennapedia cell-penetrating peptides: effects on cellular uptake, binding to target sequences, and biologic actions.

2002 • 267 citations

Integration of Polyaniline/Poly(acrylic acid) Films and Redox Enzymes on Electrode Supports: An in Situ Electrochemical/Surface Plasmon Resonance Study of the Bioelectrocatalyzed Oxidation of Glucose or Lactate in the Integrated Bioelectrocatalytic Systems

2002 • 262 citations

Direct comparison of binding equilibrium, thermodynamic, and rate constants determined by surface‐ and solution‐based biophysical methods

2002 • 261 citations

Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells and in pre-BCR triggering

2002 • 260 citations

Phosphorylation of the AP2 μ subunit by AAK1 mediates high affinity binding to membrane protein sorting signals

2002 • 257 citations

Phosphorylation of Eukaryotic Initiation Factor 4E Markedly Reduces Its Affinity for Capped mRNA

2002 • 252 citations

Platelet-derived Growth Factor (PDGF)-induced Tyrosine Phosphorylation of the Low Density Lipoprotein Receptor-related Protein (LRP)

2002 • 250 citations

Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice

2002 • 243 citations

Structural determinants for GoLoco-induced inhibition of nucleotide release by Gα subunits

2002 • 243 citations

Novel Vascular Endothelial Growth Factor Binding Domains of Fibronectin Enhance Vascular Endothelial Growth Factor Biological Activity

2002 • 241 citations

The Crystal Structure and Mode of Action of Trans-Sialidase, a Key Enzyme in Trypanosoma cruzi Pathogenesis

2002 • 238 citations

Oversulfated Chondroitin/Dermatan Sulfates Containing GlcAβ1/IdoAα1–3GalNAc(4,6-O-disulfate) Interact with L- and P-selectin and Chemokines

2002 • 237 citations

Ligand Discrimination by TPR Domains

2002 • 229 citations

Arthritogenic Monoclonal Antibodies from K/BxN Mice

2002 • 229 citations

Structural and Functional Versatility of the FHA Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2

2002 • 228 citations

Rad9 Phosphorylation Sites Couple Rad53 to the Saccharomyces cerevisiae DNA Damage Checkpoint

2002 • 227 citations

Kinetic analysis of estrogen receptor/ligand interactions

2002 • 219 citations

Molecular Cloning and Characterization of Glucanase Inhibitor Proteins

2002 • 217 citations

The SAM domain of polyhomeotic forms a helical polymer.

2002 • 212 citations

Versican Interacts with Fibrillin-1 and Links Extracellular Microfibrils to Other Connective Tissue Networks

2002 • 212 citations

Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice: involvement in mobilization of stem/progenitor cells.

2002 • 212 citations

AP-4 binds basolateral signals and participates in basolateral sorting in epithelial MDCK cells

2002 • 211 citations

Acetylation of the Yeast Histone H4 N Terminus Regulates Its Binding to Heterochromatin Protein SIR3

2002 • 211 citations

Fibroblast Growth Factor (FGF)-23 Inhibits Renal Phosphate Reabsorption by Activation of the Mitogen-activated Protein Kinase Pathway

2002 • 211 citations

Identification of the Critical Features of a Small Peptide Inhibitor of JNK Activity

2002 • 210 citations

High transcytosis of melanotransferrin (P97) across the blood–brain barrier

2002 • 209 citations

Disulfide bond-mediated dimerization of HLA-G on the cell surface

2002 • 208 citations

The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation

2002 • 207 citations

Ionomycin-activated Calpain Triggers Apoptosis

2002 • 207 citations

High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site

2002 • 201 citations

Streptococcus pneumoniaeEvades Complement Attack and Opsonophagocytosis by Expressing thepspCLocus-Encoded Hic Protein That Binds to Short Consensus Repeats 8–11 of Factor H

2002 • 200 citations

An Ephrin Mimetic Peptide That Selectively Targets the EphA2 Receptor

2002 • 200 citations

Prevention of Thecal Angiogenesis, Antral Follicular Growth, and Ovulation in the Primate by Treatment with Vascular Endothelial Growth Factor Trap R1R2

2002 • 199 citations

A therapeutic agent with oriented carbohydrates for treatment of infections by Shiga toxin-producing Escherichia coli O157:H7

2002 • 199 citations

Two-step Membrane Binding by Equinatoxin II, a Pore-forming Toxin from the Sea Anemone, Involves an Exposed Aromatic Cluster and a Flexible Helix

2002 • 199 citations

Identification of the Heparan Sulfate Binding Sites in the Cellular Prion Protein

2002 • 199 citations

Megalin Functions as an Endocytic Sonic Hedgehog Receptor

2002 • 198 citations

Analyzing Biomolecular Interactions

2002 • 197 citations

Piccolo, a Ca2+ Sensor in Pancreatic β-Cells

2002 • 193 citations

Crystal Structure of sTALL-1 Reveals a Virus-like Assembly of TNF Family Ligands

2002 • 192 citations

Biglycan Organizes Collagen VI into Hexagonal-like Networks Resembling Tissue Structures

2002 • 189 citations

PIP2-PDZ Domain Binding Controls the Association of Syntenin with the Plasma Membrane

2002 • 185 citations

Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice: involvement in mobilization of stem/progenitor cells

2002 • 185 citations

Mechanisms through which Sos-1 coordinates the activation of Ras and Rac

2002 • 182 citations

Human monocyte scavenger receptors are pattern recognition receptors for (1-->3)-beta-D-glucans.

2002 • 181 citations

Detection of Staphylococcus aureus enterotoxin B at femtomolar levels with a miniature integrated two-channel surface plasmon resonance (SPR) sensor

2002 • 181 citations

Redox Properties of CytochromecAdsorbed on Self-Assembled Monolayers: A Probe for Protein Conformation and Orientation

2002 • 179 citations

The autoregulatory role of EsaR, a quorum‐sensing regulator in Pantoea stewartii ssp. stewartii: evidence for a repressor function

2002 • 178 citations

Therapeutic efficacy of anti-ErbB2 immunoliposomes targeted by a phage antibody selected for cellular endocytosis

2002 • 178 citations

Action Range of BMP Is Defined by Its N-Terminal Basic Amino Acid Core

2002 • 175 citations

In vivo properties of an anti-GnRH Spiegelmer: An example of an oligonucleotide-based therapeutic substance class

2002 • 174 citations

cis-Acting DNA from Fission Yeast Centromeres Mediates Histone H3 Methylation and Recruitment of Silencing Factors and Cohesin to an Ectopic Site

2002 • 174 citations

pH-Dependent Intramolecular Binding and Structure Involving Cx43 Cytoplasmic Domains

2002 • 172 citations

Fibroblast growth factor–specific modulation of cellular response by syndecan-4

2002 • 170 citations

Activation of Human MutS Homologs by 8-Oxo-guanine DNA Damage

2002 • 167 citations

Structural Requirements for Potent Versus Selective Cytotoxicity for Antimicrobial Dermaseptin S4 Derivatives

2002 • 167 citations

The C‐terminal domain of perfringolysin O is an essential cholesterol‐binding unit targeting to cholesterol‐rich microdomains

2002 • 165 citations

Isolation of high-affinity GTP aptamers from partially structured RNA libraries

2002 • 163 citations

Molecular Basis of the Specific Subcellular Localization of the C2-like Domain of 5-Lipoxygenase

2002 • 162 citations

Complement Inhibitor Factor H Binding to Lyme Disease Spirochetes Is Mediated by Inducible Expression of Multiple Plasmid-Encoded Outer Surface Protein E Paralogs

2002 • 162 citations

Analysis of the Interaction of Platelet Collagen Receptor Glycoprotein VI (GPVI) with Collagen

2002 • 161 citations

Generation and Characterization of a Protective Monoclonal Antibody toPseudomonas aeruginosaPcrV

2002 • 161 citations

Phosphatidylinositol 3-Phosphate Induces the Membrane Penetration of the FYVE Domains of Vps27p and Hrs

2002 • 161 citations

Mechanism of c-Myb–C/EBPβ Cooperation from Separated Sites on a Promoter

2002 • 160 citations

TAPAS-1, a Novel Microdomain within the Unique N-terminal Region of the PDE4A1 cAMP-specific Phosphodiesterase That Allows Rapid, Ca2+-triggered Membrane Association with Selectivity for Interaction with Phosphatidic Acid

2002 • 158 citations

Interaction of Transcriptional Intermediary Factor 2 Nuclear Receptor Box Peptides with the Coactivator Binding Site of Estrogen Receptor α

2002 • 158 citations

Human monocyte scavenger receptors are pattern recognition receptors for (1→3)-β-D-glucans

2002 • 158 citations

Not All Perlecans Are Created Equal

2002 • 156 citations

Improved cytotoxic activity toward cell lines and fresh leukemia cells of a mutant anti-CD22 immunotoxin obtained by antibody phage display.

2002 • 155 citations

The Leucine-rich Repeat Protein PRELP Binds Perlecan and Collagens and May Function as a Basement Membrane Anchor

2002 • 153 citations

TraG-Like Proteins of DNA Transfer Systems and of theHelicobacter pyloriType IV Secretion System: Inner Membrane Gate for Exported Substrates?

2002 • 153 citations

Megalin and Cubilin are Endocytic Receptors Involved in Renal Clearance of Hemoglobin

2002 • 151 citations

Tanis: A Link Between Type 2 Diabetes and Inflammation?

2002 • 151 citations

Oligomeric and Conformational Properties of a Proteolytically Mature, Disulfide-Stabilized Human Immunodeficiency Virus Type 1 gp140 Envelope Glycoprotein

2002 • 151 citations

The RAS Effector RIN1 Directly Competes with RAF and Is Regulated by 14-3-3 Proteins

2002 • 150 citations

Kinetic studies of RNA–protein interactions using surface plasmon resonance

2002 • 149 citations

Relationships between Structure and Interaction Kinetics for HIV-1 Protease Inhibitors

2002 • 148 citations

Rational cytokine design for increased lifetime and enhanced potency using pH-activated “histidine switching”

2002 • 148 citations

Homo- and Heterotypic Fibrillin-1 and -2 Interactions Constitute the Basis for the Assembly of Microfibrils

2002 • 148 citations

Protein-dependent ribozymes report molecular interactions in real time

2002 • 147 citations

Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor

2002 • 147 citations

Structural basis for the unusual carbohydrate-binding specificity of jacalin towards galactose and mannose

2002 • 146 citations

Mapping the Type I Collagen-binding Site on Pigment Epithelium-derived Factor

2002 • 146 citations

Fully human, HLA-DR-specific monoclonal antibodies efficiently induce programmed death of malignant lymphoid cells

2002 • 145 citations

A linear lattice model for polyglutamine in CAG-expansion diseases

2002 • 144 citations

Early Endosomal Regulation of Smad-dependent Signaling in Endothelial Cells

2002 • 143 citations

Paip1 Interacts with Poly(A) Binding Protein through Two Independent Binding Motifs

2002 • 141 citations

B Lymphocyte Memory

2002 • 139 citations

Real-Time Analysis of Ligand-Induced Cell Surface and Intracellular Reactions of Living Mast Cells Using a Surface Plasmon Resonance-Based Biosensor

2002 • 139 citations

Differential Effects of Heparin Saccharides on the Formation of Specific Fibroblast Growth Factor (FGF) and FGF Receptor Complexes

2002 • 138 citations

Phage versus Phagemid Libraries for Generation of Human Monoclonal Antibodies

2002 • 136 citations

A Model System Mimicking Glycosphingolipid Clusters to Quantify Carbohydrate Self-Interactions by Surface Plasmon Resonance

2002 • 136 citations

Follistatin Regulates Bone Morphogenetic Protein-7 (BMP-7) Activity to Stimulate Embryonic Muscle Growth

2002 • 135 citations

SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2beta1

2002 • 134 citations

Suppressor of Cytokine Signaling-3 Is Recruited to the Activated Granulocyte-Colony Stimulating Factor Receptor and Modulates its Signal Transduction

2002 • 133 citations

Biosensors: new approaches in drug discovery

2002 • 131 citations

An In-Depth Analysis of Electric Cell−Substrate Impedance Sensing To Study the Attachment and Spreading of Mammalian Cells

2002 • 131 citations

The solution structure and DNA-binding properties of the cold-shock domain of the human Y-box protein YB-1

2002 • 131 citations

Biosensors for DNA sequence detection

2002 • 131 citations

Interactions of β and γENaC with Nedd4 Can Be Facilitated by an ERK-mediated Phosphorylation

2002 • 129 citations

Structural analysis of the adaptor protein ClpS in complex with the N-terminal domain of ClpA

2002 • 128 citations

The Vα14 NKT Cell TCR Exhibits High-Affinity Binding to a Glycolipid/CD1d Complex

2002 • 128 citations

The protein import motor of mitochondria: a targeted molecular ratchet driving unfolding and translocation

2002 • 128 citations

Interaction of Fibrin(ogen) with Fibronectin: Further Characterization and Localization of the Fibronectin-Binding Site

2002 • 128 citations

Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1

2002 • 128 citations

Layer-by-layer assembly of multilayer films composed of avidin and biotin-labeled antibody for immunosensing

2002 • 127 citations

Analytical methods to identify irradiated food—a review

2002 • 127 citations

Direct Assay for Cobalamin Bound to Transcobalamin (Holo-Transcobalamin) in Serum

2002 • 127 citations

A Direct Interaction between the Survival Motor Neuron Protein and p53 and Its Relationship to Spinal Muscular Atrophy

2002 • 126 citations

Complement C3b/C3d and Cell Surface Polyanions Are Recognized by Overlapping Binding Sites on the Most Carboxyl-Terminal Domain of Complement Factor H

2002 • 126 citations

Human neutrophil lipocalin is a unique marker of neutrophil inflammation in ulcerative colitis and proctitis

2002 • 125 citations

Bacterially expressed and refolded receptor binding domain of Plasmodium falciparum EBA-175 elicits invasion inhibitory antibodies

2002 • 124 citations

Protein–heparin interactions measured by BIAcore 2000 are affected by the method of heparin immobilization

2002 • 124 citations

A method for the generation of combinatorial antibody libraries using pIX phage display

2002 • 124 citations

Molecular coordination of αβ T-cell receptors and coreceptors CD8 and CD4 in their recognition of peptide-MHC ligands

2002 • 123 citations

Characterization of the Vitamin E-Binding Properties of Human Plasma Afamin

2002 • 122 citations

The metabolic activation of abacavir by human liver cytosol and expressed human alcohol dehydrogenase isozymes

2002 • 121 citations

Surface adhesion of fusion proteins containing the hydrophobins HFBI and HFBII from Trichoderma reesei

2002 • 121 citations

Epitope mapping of a monoclonal antibody against human thrombin by H/D‐exchange mass spectrometry reveals selection of a diverse sequence in a highly conserved protein

2002 • 120 citations

Calmodulin and lipid binding to synaptobrevin regulates calcium-dependent exocytosis

2002 • 120 citations

KDR (VEGF Receptor 2) Is the Major Mediator for the Hypotensive Effect of VEGF

2002 • 119 citations

Intraneuronal APP/Aβ Trafficking and Plaque Formation in β‐Amyloid Precursor Protein and Presenilin‐1 Transgenic Mice

2002 • 119 citations

Interactions defining the specificity between fungal xylanases and the xylanase-inhibiting protein XIP-I from wheat

2002 • 118 citations

Tumour necrosis factor‐α interacts with biglycan and decorin

2002 • 118 citations

Is the GehD Lipase from Staphylococcus epidermidis a Collagen Binding Adhesin?

2002 • 116 citations

Selection by phage display of llama conventional VH fragments with heavy chain antibody VHH properties

2002 • 116 citations

DEAD Box RhlB RNA Helicase Physically Associates with Exoribonuclease PNPase to Degrade Double-stranded RNA Independent of the Degradosome-assembling Region of RNase E

2002 • 116 citations

The N-terminal SH2 Domains of Syk and ZAP-70 Mediate Phosphotyrosine-independent Binding to Integrin β Cytoplasmic Domains

2002 • 116 citations

Evidence for a Direct Interaction between the Tumor Suppressor Serpin, Maspin, and Types I and III Collagen

2002 • 116 citations

Surface plasmon resonance spectroscopy: An emerging tool for the study of peptide–membrane interactions

2002 • 116 citations

Kinetic Modeling and Determination of Reaction Constants of Alzheimer's β-Amyloid Fibril Extension and Dissociation Using Surface Plasmon Resonance

2002 • 116 citations

Endostatin binds to the catalytic domain of matrix metalloproteinase‐2

2002 • 115 citations

Fibroblast growth factor-2 binds to small heparin-derived oligosaccharides and stimulates a sustained phosphorylation of p42/44 mitogen-activated protein kinase and proliferation of rat mammary fibroblasts

2002 • 114 citations

Cytoplasmic trafficking of IGF-II mRNA-binding protein by conserved KH domains

2002 • 114 citations

Biosensor technologies for detecting microbiological foodborne hazards

2002 • 114 citations

Differences in Electrostatic Properties at Antibody–Antigen Binding Sites: Implications for Specificity and Cross-Reactivity

2002 • 114 citations

Unfolding of quadruplex structure in the G-rich strand of the minisatellite repeat by the binding protein UP1

2002 • 113 citations

Affinity-Based Inhibition of β-Amyloid Toxicity

2002 • 113 citations

Surface plasmon resonance characterization of drug/liposome interactions

2002 • 113 citations

Identification and Characterization of a Regulatory Domain on the Carboxyl Terminus of the Measles Virus Nucleocapsid Protein

2002 • 113 citations

Heterogeneous Nuclear Ribonucleoprotein A3, a Novel RNA Trafficking Response Element-binding Protein

2002 • 111 citations

Application of Natural Receptors in Sensors and Assays

2002 • 111 citations

Structural and Thermodynamic Correlates of T Cell Signaling

2002 • 110 citations

SH2 Domains from Suppressor of Cytokine Signaling-3 and Protein Tyrosine Phosphatase SHP-2 Have Similar Binding Specificities

2002 • 110 citations

Molecular interactions between desmosomal cadherins

2002 • 110 citations

Intranasal immunization with recombinant antigens associated with new cationic particles induces strong mucosal as well as systemic antibody and CTL responses

2002 • 109 citations

Delphilin: a Novel PDZ and Formin Homology Domain-Containing Protein that Synaptically Colocalizes and Interacts with Glutamate Receptor δ2 Subunit

2002 • 109 citations

Glycosylation of Erythropoietin Affects Receptor Binding Kinetics: Role of Electrostatic Interactions

2002 • 109 citations

Rapid monitoring of recombinant protein products: a comparison of current technologies

2002 • 109 citations

Titin‐cap associates with, and regulates secretion of, Myostatin

2002 • 108 citations

Cytotoxic Cell Granule-mediated Apoptosis

2002 • 108 citations

Identification of Novel Interactions Between Domains of Myosin Binding Protein-C That Are Modulated by Hypertrophic Cardiomyopathy Missense Mutations

2002 • 108 citations

Metformin Effects on Dipeptidylpeptidase IV Degradation of Glucagon-like Peptide-1

2002 • 107 citations

Factor XI Binding to the Platelet Glycoprotein Ib-IX-V Complex Promotes Factor XI Activation by Thrombin

2002 • 107 citations

Comparison of reflectometric interference spectroscopy with other instruments for label-free optical detection

2001 • 106 citations

Phosphatidylserine Binding of Class B Scavenger Receptor Type I, a Phagocytosis Receptor of Testicular Sertoli Cells

2002 • 105 citations

Detection of streptomycin and dihydrostreptomycin residues in milk, honey and meat samples using an optical biosensor

2002 • 105 citations

Surface plasmon resonance biosensor for genetically modified organisms detection

2002 • 105 citations

Biosensor Technology and Surface Plasmon Resonance for Real-Time Detection of Genetically Modified Roundup Ready Soybean Gene Sequences

2002 • 104 citations

Associations of B- and C-Raf with Cholesterol, Phosphatidylserine, and Lipid Second Messengers

2002 • 104 citations

The Cytoplasmic Tail of L-selectin Interacts with Members of the Ezrin-Radixin-Moesin (ERM) Family of Proteins

2002 • 103 citations

Use of Biomolecular Interaction Analysis to Elucidate the Regulatory Mechanism of the Cysteine Synthase Complex fromArabidopsis thaliana

2002 • 103 citations

ParB-Stimulated Nucleotide Exchange Regulates a Switch in Functionally Distinct ParA Activities

2002 • 102 citations

CX3CR1 Tyrosine Sulfation Enhances Fractalkine-induced Cell Adhesion

2002 • 102 citations

Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins

2002 • 102 citations

Comparison of Interleukin-22 and Interleukin-10 Soluble Receptor Complexes

2002 • 101 citations

Development and validation of a biosensor-based immunoassay for progesterone in bovine milk

2002 • 101 citations

New Class of HIV Integrase Inhibitors that Block Viral Replication in Cell Culture

2002 • 101 citations

β-Arrestin Binding to CC Chemokine Receptor 5 Requires Multiple C-terminal Receptor Phosphorylation Sites and Involves a Conserved Asp-Arg-Tyr Sequence Motif

2002 • 100 citations

Engineering receptors and antibodies for biosensors

2002 • 99 citations

The Type XIII Collagen Ectodomain Is a 150-nm Rod and Capable of Binding to Fibronectin, Nidogen-2, Perlecan, and Heparin

2002 • 99 citations

Flow-Mediated On-Surface Reconstitution of G-Protein Coupled Receptors for Applications in Surface Plasmon Resonance Biosensors

2002 • 99 citations

The ISOBM TD-7 Workshop on hCG and Related Molecules

2002 • 97 citations

Survey of the year 2001 commercial optical biosensor literature

2002 • 97 citations

Towards quantitative assays with peptide chips: a surface engineering approach

2002 • 97 citations

Calcium- and Myristoyl-Dependent Properties of Guanylate Cyclase-Activating Protein-1 and Protein-2

2002 • 96 citations

Genetic and immunological comparison of anti-botulinum type A antibodies from immune and non-immune human phage libraries

2002 • 96 citations

Development and validation of a quantitative ELISA for the measurement of PSA concentration

2002 • 96 citations

Fibroblast Growth Factor Receptors 1 and 2 Interact Differently with Heparin/Heparan Sulfate

2002 • 96 citations

Regulation of tyrosine hydroxylase by stress‐activated protein kinases

2002 • 95 citations

A Mosquito Salivary Protein Inhibits Activation of the Plasma Contact System by Binding to Factor XII and High Molecular Weight Kininogen

2002 • 95 citations

Human immunoglobulin A (IgA)‐specific ligands from combinatorial engineering of protein A

2002 • 95 citations

A new high affinity binding site for suppressor of cytokine signaling‐3 on the erythropoietin receptor

2002 • 94 citations

Estrogen receptor binding assay of chemicals with a surface plasmon resonance biosensor

2002 • 94 citations

GnRH Binding RNA and DNA Spiegelmers

2002 • 94 citations

The Matrix Metalloproteinase 9 (MMP-9) Hemopexin Domain Is a Novel Gelatin Binding Domain and Acts as an Antagonist

2002 • 94 citations

Intracellular trafficking pathway of newly synthesized CD1b molecules

2002 • 93 citations

High-affinity binding of recombinant human galectin-4 to SO3-->3Gal 1->3GalNAc pyranoside

2002 • 93 citations

Viral chemokine-binding proteins

2002 • 93 citations

Synergistic Antitumor Effect of Bispecific CD19 × CD3 and CD19 × CD16 Diabodies in a Preclinical Model of Non-Hodgkin’s Lymphoma

2002 • 92 citations

A study of the vaccinia virus interferon-γ receptor and its contribution to virus virulence

2002 • 92 citations

The Src homology 2 domain–containing inositol 5-phosphatase negatively regulates Fcγ receptor–mediated phagocytosis through immunoreceptor tyrosine-based activation motif–bearing phagocytic receptors

2002 • 92 citations

Protein chips: from concept to practice

2002 • 92 citations

A Mutational Analysis of the Globotriaosylceramide-binding Sites of Verotoxin VT1

2002 • 92 citations

Membrane Targeting of C2 Domains of Phospholipase C-δ Isoforms

2002 • 91 citations

Kinetic Analysis of the Interleukin-13 Receptor Complex

2002 • 91 citations

Localization of VEGF receptor-2 (KDR/Flk-1) and effects of blocking it in oxygen-induced retinopathy.

2002 • 91 citations

Disabling Receptor Ensembles with Rationally Designed Interface Peptidomimetics

2002 • 90 citations

Probing Antigen−Antibody Binding Processes by Impedance Measurements on Ion-Sensitive Field-Effect Transistor Devices and Complementary Surface Plasmon Resonance Analyses: Development of Cholera Toxin Sensors

2002 • 90 citations

Asymmetric SPR sensor response curve-fitting equation for the accurate determination of SPR resonance angle

2002 • 89 citations

Interaction between Erbin and a Catenin-related Protein in Epithelial Cells

2002 • 89 citations

The family of hepatoma-derived growth factor proteins: characterization of a new member HRP-4 and classification of its subfamilies

2002 • 89 citations

SAR and X-ray. A New Approach Combining Fragment-Based Screening and Rational Drug Design: Application to the Discovery of Nanomolar Inhibitors of Src SH2

2002 • 89 citations

Direct in Vivo Screening of Intrabody Libraries Constructed on a Highly Stable Single-chain Framework

2002 • 87 citations

Mutational analysis of human profilin I reveals a second PI(4,5)-P2 binding site neighbouring the poly(L-proline) binding site.

2002 • 87 citations

Antibody–antigen kinetics following immunization of rainbow trout (Oncorhynchus mykiss) with a T-cell dependent antigen

2002 • 87 citations

Antibodies Highly Effective in SCID Mice During Infection by the Intracellular BacteriumEhrlichia chaffeensisAre of Picomolar Affinity and Exhibit Preferential Epitope and Isotype Utilization

2002 • 86 citations

Functional proteomics; current achievements

2002 • 86 citations

Structural and Guanosine Triphosphate/Diphosphate Requirements for Transit Peptide Recognition by the Cytosolic Domain of the Chloroplast Outer Envelope Receptor, Toc34

2002 • 86 citations

Selective Intracellular Delivery of Dexamethasone into Activated Endothelial Cells Using an E-Selectin-Directed Immunoconjugate

2002 • 86 citations

Selection and Stabilization of the RNA Aptamers against the Human Immunodeficiency Virus Type-1 Nucleocapsid Protein

2002 • 86 citations

Acceptance of analytical methods for implementation of EU legislation with a focus on mycotoxins

2002 • 86 citations

Crystal Structure of a C-terminal Fragment of Growth Arrest-specific Protein Gas6

2002 • 85 citations

In vitro folding, functional characterization, and disulfide pattern of the extracellular domain of human GLP-1 receptor

2002 • 85 citations

Isolation and Detection of Human IgA Using a Streptococcal IgA-Binding Peptide

2002 • 84 citations

Molecular interactions between desmosomal cadherins

2002 • 84 citations

Regulatory Effect of IFN-κ, A Novel Type I IFN, On Cytokine Production by Cells of the Innate Immune System

2002 • 84 citations

Determination of Active Concentrations and Association and Dissociation Rate Constants of Interacting Biomolecules: An Analytical Solution to the Theory for Kinetic and Mass Transport Limitations in Biosensor Technology and Its Experimental Verification

2002 • 83 citations

Binding of Inositol Hexakisphosphate (IP6) to Ku but Not to DNA-PKcs

2002 • 83 citations

ETS-1 Transcription Factor Binds Cooperatively to the Palindromic Head to Head ETS-binding Sites of the Stromelysin-1 Promoter by Counteracting Autoinhibition

2002 • 83 citations

Macrocyclic Glycoclusters. Self-Aggregation and Phosphate-Induced Agglutination Behaviors of Calix[4]resorcarene-Based Quadruple-Chain Amphiphiles with a Huge Oligosaccharide Pool

2002 • 83 citations

The Primary Antibody Repertoire Represents a Linked Network of Degenerate Antigen Specificities

2002 • 82 citations

Identification of distinct antibody epitopes and mimotopes from a peptide array of 5520 randomly generated sequences

2002 • 82 citations

Rhamnose-binding Lectins from Steelhead Trout (Oncorhynchus mykiss) Eggs Recognize Bacterial Lipopolysaccharides and Lipoteichoic Acid

2002 • 82 citations

Induction of Neuronal Differentiation by a Peptide Corresponding to the Homophilic Binding Site of the Second Ig Module of the Neural Cell Adhesion Molecule

2002 • 82 citations

Direct Interaction of the NifL Regulatory Protein with the GlnK Signal Transducer Enables the Azotobacter vinelandiiNifL-NifA Regulatory System to Respond to Conditions Replete for Nitrogen

2002 • 82 citations

Three semidominant barley mutants with single amino acid substitutions in the smallest magnesium chelatase subunit form defective AAA ⁺ hexamers

2002 • 82 citations

Nuclear organization in differentiating oligodendrocytes

2002 • 81 citations

Intracellular distribution of viral gene products regulates a complex mechanism of cauliflower mosaic virus acquisition by its aphid vector

2002 • 81 citations

Microchip-based high-throughput screening analysis of combinatorial libraries

2002 • 81 citations

Translocation of an Intracellular Antigen to the Surface of Medullary Breast Cancer Cells Early in Apoptosis Allows for an Antigen-Driven Antibody Response Elicited by Tumor-Infiltrating B Cells

2002 • 81 citations

Structural basis of BLyS receptor recognition

2002 • 81 citations

Protein-Protein Interactions That Regulate the Energy Stress Activation of σ^BinBacillus subtilis

2002 • 80 citations

Contrasting, Species-Dependent Modulation of Copper-Mediated Neurotoxicity by the Alzheimer's Disease Amyloid Precursor Protein

2002 • 80 citations

Kinetic Analysis of Glycoprotein C of Herpes Simplex Virus Types 1 and 2 Binding to Heparin, Heparan Sulfate, and Complement Component C3b

2002 • 80 citations

Development of protein-detecting microarrays and related devices

2002 • 79 citations

Influence of a Terminal Formamido Group on the Sequence Recognition of DNA by Polyamides

2002 • 79 citations

Antigen-stimulated Activation of Phospholipase D1b by Rac1, ARF6, and PKCα in RBL-2H3 Cells

2002 • 79 citations

Evidence of a trimolecular complex involving LPS, LPS binding protein and soluble CD14 as an effector of LPS response

2002 • 79 citations

Determination of Vitamin B12 in Milk Products and Selected Foods by Optical Biosensor Protein-Binding Assay: Method Comparison

2002 • 79 citations

C‐reactive protein‐mediated phagocytosis and phospholipase D signalling through the high‐affinity receptor for immunoglobulin G (FcγRI)

2002 • 78 citations

Specific Characterization of Substrate and Inhibitor Binding Sites of a Glycosyl Hydrolase Family 11 Xylanase fromAspergillus niger

2002 • 78 citations

Ligands for murine NKG2D display heterogeneous binding behavior

2002 • 78 citations

Reductionism and the search for structure–function relationships in antibody molecules

2002 • 77 citations

The μ2 Subunit of the Clathrin Adaptor AP-2 Binds to FDNPVY and YppØ Sorting Signals at Distinct Sites

2002 • 77 citations

Biosensor analysis of penicillin G in milk based on the inhibition of carboxypeptidase activity

2002 • 77 citations

Evanescent wave biosensors

1995 • 77 citations

Characterization of the H-kininogen-binding Site on Factor XI

2002 • 77 citations

Regulation of Exocytosis through Ca²⁺/ATP-Dependent Binding of Autophosphorylated Ca²⁺/Calmodulin-Activated Protein Kinase II to Syntaxin 1A

2002 • 76 citations

Domain Organization of D-AKAP2 Revealed by Enhanced Deuterium Exchange-Mass Spectrometry (DXMS)

2002 • 76 citations

Binding of the Natural Killer Cell Inhibitory Receptor Ly49A to Its Major Histocompatibility Complex Class I Ligand

2002 • 76 citations

Selective Immobilization of Multivalent Ligands for Surface Plasmon Resonance and Fluorescence Microscopy

2002 • 76 citations

Biochemical and Biological Characterization of a Dodecameric CD4-Ig Fusion Protein

2002 • 76 citations

Tumor targeting properties of monoclonal antibodies with different affinity for target antigen CD44V6 in nude mice bearing head‐and‐neck cancer xenografts

2002 • 76 citations

Tight Binding of the Antitumor Drug Ditercalinium to Quadruplex DNA

2002 • 76 citations

Identification of hNopp140 as a Binding Partner for Doxorubicin with a Phage Display Cloning Method

2002 • 75 citations

A Plant Phytotoxin, Solanapyrone A, Is an Inhibitor of DNA Polymerase β and λ

2002 • 75 citations

TCR-Like Human Antibodies Expressed on Human CTLs Mediate Antibody Affinity-Dependent Cytolytic Activity

2002 • 75 citations

A Kinetics and Modeling Study of RANTES(9−68) Binding to Heparin Reveals a Mechanism of Cooperative Oligomerization

2002 • 75 citations

Monoclonal Antibodies Selective for Low Molecular Weight Neurofilaments

2002 • 75 citations

Molecular basis of non-self recognition by the horseshoe crab tachylectins

2002 • 75 citations

Roles of Catalytic Domain Residues in Interfacial Binding and Activation of Group IV Cytosolic Phospholipase A2

2002 • 74 citations

E. coli Expression of TIMP-4 and Comparative Kinetic Studies with TIMP-1 and TIMP-2: Insights into the Interactions of TIMPs and Matrix Metalloproteinase 2 (Gelatinase A)

2002 • 73 citations

Calcium-mediated Association of a Putative Vacuolar Sorting Receptor PV72 with a Propeptide of 2S Albumin

2002 • 73 citations

Stable self‐assembly of a protein engineering scaffold on gold surfaces

2002 • 73 citations

The Spectrin-Ankyrin Skeleton Controls CD45 Surface Display and Interleukin-2 Production

2002 • 73 citations

Some new aspects in biosensors

2002 • 73 citations

Kinetic Analysis of the Interaction between Vitronectin and the Urokinase Receptor

2002 • 73 citations

Molecular and biochemical characterization of a calcium/calmodulin-binding protein kinase from rice

2002 • 73 citations

Interaction of Fibrin(ogen) with the Endothelial Cell Receptor VE-Cadherin: Mapping of the Receptor-Binding Site in the NH₂-Terminal Portions of the Fibrin β Chains

2002 • 72 citations

Hydropathic Complementarity Determines Interaction of Epitope 869HITDTNNK876 in Manduca sexta Bt-R1 Receptor with Loop 2 of Domain II ofBacillus thuringiensis Cry1A Toxins

2002 • 72 citations

Multiple Interference of Anthracyclines with Mitochondrial Creatine Kinases: Preferential Damage of the Cardiac Isoenzyme and Its Implications for Drug Cardiotoxicity

2002 • 72 citations

Distinct Kinetics for Binding of the CD46 and SLAM Receptors to Overlapping Sites in the Measles Virus Hemagglutinin Protein

2002 • 71 citations

Generation of therapeutic antibody responses against IgE through vaccination

2002 • 71 citations

Characterization of the Interaction Between L-Ficolin/P35 and Mannan-Binding Lectin-Associated Serine Proteases-1 and -2

2002 • 70 citations

Strong Binding in the DNA Minor Groove by an Aromatic Diamidine with a Shape That Does Not Match the Curvature of the Groove

2002 • 70 citations

Preassembly of Membrane-Active Peptides Is an Important Factor in Their Selectivity toward Target Cells

2002 • 70 citations

Design and Parallel Solid-Phase Synthesis of Ring-Fused 2-Pyridinones That Target Pilus Biogenesis in Pathogenic Bacteria

2002 • 70 citations

ALG-2 Interacts with the Amino-Terminal Domain of Annexin XI in a Ca2+-Dependent Manner

2002 • 70 citations

Analysis of the Human Replication Protein A:Rad52 Complex: Evidence for Crosstalk Between RPA32, RPA70, Rad52 and DNA

2002 • 70 citations

A novel type of co-chaperone mediates transmembrane recruitment of DnaK-like chaperones to ribosomes

2002 • 70 citations

Knowledge-based Design of Reagentless Fluorescent Biosensors from Recombinant Antibodies

2002 • 70 citations

The penta-EF-hand domain of ALG-2 interacts with amino-terminal domains of both annexin VII and annexin XI in a Ca2+-dependent manner

2002 • 69 citations

Engineering streptococcal protein G for increased alkaline stability

2002 • 69 citations

NAD Binding Induces Conformational Changes in Rho ADP-ribosylating Clostridium botulinum C3 Exoenzyme

2002 • 67 citations

An Absorption-Based Surface Plasmon Resonance Sensor Applied to Sodium Ion Sensing Based on an Ion-Selective Optode Membrane

2002 • 67 citations

Surface plasmon resonance (BIACORE) detection of serum antibodies against Salmonella enteritidis and Salmonella typhimurium

2002 • 67 citations

Minute Virus of Mice NS1 Interacts with the SMN Protein, and They Colocalize in Novel Nuclear Bodies Induced by Parvovirus Infection

2002 • 67 citations

High Affinity Mimotope of the Polysaccharide Capsule of Cryptococcus neoformans Identified from an Evolutionary Phage Peptide Library

2002 • 67 citations

Aspartic Acid 564 in the Third Cytoplasmic Loop of the Luteinizing Hormone/Choriogonadotropin Receptor Is Crucial for Phosphorylation-independent Interaction with Arrestin2

2002 • 67 citations

A New Consensus Sequence for Phosphatidylserine Recognition by Annexins

2002 • 67 citations

High affinity nucleic acid aptamers for streptavidin incorporated into bi-specific capture ligands

2002 • 66 citations

Apical Loop−Internal Loop Interactions: A New RNA−RNA Recognition Motif Identified through in Vitro Selection against RNA Hairpins of the Hepatitis C Virus mRNA

2002 • 66 citations

Binding of FGF-1 variants to protein kinase CK2 correlates with mitogenicity

2002 • 66 citations

A naturally occurring NAR variable domain binds the Kgp protease from Porphyromonas gingivalis

2002 • 66 citations

A Novel Protein-Protein Interaction between a G Protein-coupled Receptor and the Phosphatase SHP-2 Is Involved in Bradykinin-induced Inhibition of Cell Proliferation

2002 • 66 citations

Multivalent interactions between biotin–polyrotaxane conjugates and streptavidin as a model of new targeting for transporters

2002 • 65 citations

Ca2+-Myristoyl Switch in the Neuronal Calcium Sensor Recoverin Requires Different Functions of Ca2+-binding Sites

2002 • 65 citations

GyrI: a counter‐defensive strategy against proteinaceous inhibitors of DNA gyrase

2002 • 65 citations

Dominant Saccharomyces cerevisiae msh6 Mutations Cause Increased Mispair Binding and Decreased Dissociation from Mispairs by Msh2-Msh6 in the Presence of ATP

2002 • 64 citations

Adaptor Protein Shc Is an Isoform-specific Direct Activator of the Tyrosine Kinase c-Src

2002 • 64 citations

Characteristics of binding of insulin‐like growth factor (IGF)‐I and IGF‐II analogues to the type 1 IGF receptor determined by BIAcore analysis

2002 • 64 citations

Domain Structure of Chondroitin Sulfate E Octasaccharides Binding to Type V Collagen

2002 • 64 citations

HNPCC mutations in hMSH2 result in reduced hMSH2-hMSH6 molecular switch functions

2002 • 63 citations

An engineered IN-1 Fab fragment with improved affinity for the Nogo-A axonal growth inhibitor permits immunochemical detection and shows enhanced neutralizing activity

2002 • 63 citations

Structural characterization of a 2′F-RNA aptamer that binds a HIV-1 SU glycoprotein, gp120

2002 • 63 citations

ERBIN associates with p0071, an armadillo protein, at cell‐cell junctions of epithelial cells

2002 • 63 citations

Subcloning, Expression, Purification, and Characterization of Recombinant Human Leptin-binding Domain

2002 • 62 citations

Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin α3B and α5 chains

2002 • 62 citations

Membrane-immobilized haptoglobin as affinity matrix for a hemoglobin-A1c immunosensor

2002 • 62 citations

On the binding of complement to solid artificial surfaces in vitro

2002 • 62 citations

Distribution of furamidine analogues in tumor cells: targeting of the nucleus or mitochondria depending on the amidine substitution.

2002 • 62 citations

Interaction Properties of the Procollagen C-proteinase Enhancer Protein Shed Light on the Mechanism of Stimulation of BMP-1

2002 • 62 citations

Transcriptional activating regions target a cyclin-dependent kinase

2002 • 61 citations

Surface Plasmon Resonance Study on the Interaction between Lactose-Installed Poly(ethylene glycol)−Poly(<scp>d</scp>,<scp>l</scp>-lactide) Block Copolymer Micelles and Lectins Immobilized on a Gold Surface

2002 • 61 citations

Surfactant Protein A Inhibits Lipopolysaccharide-Induced Immune Cell Activation by Preventing the Interaction of Lipopolysaccharide with Lipopolysaccharide-Binding Protein

2002 • 60 citations

1,1′-Binaphthyl-Substituted Macrocycles as Receptors for Saccharide Recognition

2002 • 60 citations

Epitopic characterization of native bovine β-lactoglobulin

2002 • 60 citations

Matrilin-2 interacts with itself and with other extracellular matrix proteins

2002 • 60 citations

Influence of the Isotype of the Light Chain on the Properties of IgG

2002 • 60 citations

Functional Immobilization of a Ligand-Activated G-Protein-Coupled Receptor

2002 • 60 citations

Soluble CD30 binds to CD153 with high affinity and blocks transmembrane signaling by CD30

2002 • 59 citations

Comparison of CD22 binding to native CD45 and synthetic oligosaccharide

2002 • 59 citations

Phage N15 Telomere Resolution

2002 • 59 citations

Design, production, and characterization of a monomeric streptavidin and its application for affinity purification of biotinylated proteins

2002 • 59 citations

Electrical contacting of glucose dehydrogenase by the reconstitution of a pyrroloquinoline quinone-functionalized polyaniline film associated with an Au-electrode: an in situ electrochemical SPR study

2002 • 59 citations

Minimal Heparin/Heparan Sulfate Sequences for Binding to Fibroblast Growth Factor-1

2002 • 59 citations

Mechanism of the gBP21-mediated RNA/RNA annealing reaction: matchmaking and charge reduction

2002 • 59 citations

Mutational analysis of the interaction between albumin‐binding domain from streptococcal protein G and human serum albumin

2002 • 58 citations

Immunosensors for Pesticide Analysis: Antibody Production and Sensor Development

2002 • 57 citations

Adenovirus Protein Involved in Virus Internalization Recruits Ubiquitin−Protein Ligases

2002 • 57 citations

Determinants of Ligand Specificity in Groups I and IV WW Domains as Studied by Surface Plasmon Resonance and Model Building

2002 • 57 citations

Analysis of Biomolecular Interactions Using a Miniaturized Surface Plasmon Resonance Sensor

2002 • 57 citations

Interaction of Kazal-type Inhibitor Domains with Serine Proteinases: Biochemical and Structural Studies

2002 • 57 citations

High-Avidity, Low-Affinity Multivalent Interactions and the Block to Polyspermy in Xenopus laevis

2002 • 57 citations

Influence of compound structure on affinity, sequence selectivity, and mode of binding to DNA for unfused aromatic dications related to furamidine

2002 • 56 citations

Dimeric Versions of Two Short N-cadherin Binding Motifs (HAVDI and INPISG) Function as N-cadherin Agonists

2002 • 56 citations

Ca2+ sensor S100beta-modulated sites of membrane guanylate cyclase in thephotoreceptor-bipolar synapse

2002 • 56 citations

Regulation of PKCα Activity by C1-C2 Domain Interactions

2002 • 56 citations

A Highly Stable Covalent Conjugated Heparin Biochip for Heparin–Protein Interaction Studies

2002 • 56 citations

Generating p53-specific cytotoxic T lymphocytes by recombinant adenoviral vector-based vaccination in mice, but not man

2002 • 56 citations

Construction and characterization of affibody-Fc chimeras produced in Escherichia coli

2002 • 56 citations

Expression of IL-17B in neurons and evaluation of its possible role in the chromosome 5q-linked form of Charcot–Marie–Tooth disease

2002 • 55 citations

Complex Formation between Tap and p15 Affects Binding to FG-repeat Nucleoporins and Nucleocytoplasmic Shuttling

2002 • 55 citations

Duplicated Binding Sites for (1→3)-β-d-Glucan in the Horseshoe Crab Coagulation Factor G

2002 • 55 citations

YEAF1/RYBP and YAF-2 Are Functionally Distinct Members of a Cofactor Family for the YY1 and E4TF1/hGABP Transcription Factors

2002 • 54 citations

The High Specificities of Phaseolus vulgaris Erythro- and Leukoagglutinating Lectins for Bisecting GlcNAc or β1–6-Linked Branch Structures, Respectively, Are Attributable to Loop B

2002 • 54 citations

Identification of HIV-1 nucleocapsid protein: nucleic acid antagonists with cellular anti-HIV activity

2002 • 54 citations

Novel complexes of mammalian translation elongation factor eEF1A·GDP with uncharged tRNA and aminoacyl‐tRNA synthetase

2002 • 53 citations

Integrin αvβ3‐targeted therapy for Kaposi's sarcoma with an in vitro‐evolved antibody

2002 • 53 citations

Small molecule modulators of HIV Rev/Rev response element interaction identified by random screening

2002 • 53 citations

Mass Spectrometry after Capture and Small-Volume Elution of Analyte from a Surface Plasmon Resonance Biosensor

2002 • 53 citations

Use of Amide Exchange Mass Spectrometry To Study Conformational Changes within the Endopolygalacturonase II−Homogalacturonan−Polygalacturonase Inhibiting Protein System

2002 • 53 citations

Mass spectrometry and hyphenated techniques in neuropeptide research

2002 • 53 citations

Kinetic and Affinity Predictions of a Protein-Protein Interaction Using Multivariate Experimental Design

2002 • 53 citations

Crystal Structure of an in Vitro Affinity- and Specificity-matured Anti-testosterone Fab in Complex with Testosterone

2002 • 53 citations

Specific inhibition of P-selectin–mediated cell adhesion by phage display–derived peptide antagonists

2002 • 53 citations

Allosteric Communication between Signal Peptides and the SecA Protein DEAD Motor ATPase Domain

2002 • 53 citations

Hepatocyte Growth Factor/Scatter Factor Binds to Small Heparin-derived Oligosaccharides and Stimulates the Proliferation of Human HaCaT Keratinocytes

2002 • 53 citations

On-line detection of sulfamethazine and sulfadiazine in porcine bile using a multi-channel high-throughput SPR biosensor

2002 • 52 citations

Surface plasmon resonance measurement of pH-induced responses of immobilized biomolecules: conformational change or electrostatic interaction effects?

2002 • 52 citations

Uncoupling Kapβ2 Substrate Dissociation and Ran Binding

2002 • 52 citations

Mapping the domains of the cytoadherence ligand Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) that bind to the knob-associated histidine-rich protein (KAHRP)

2002 • 52 citations

Binding Properties of Insulin-Like Growth Factor Binding Protein-3 (IGFBP-3), IGFBP-3 N- and C-Terminal Fragments, and Structurally Related Proteins mac25 and Connective Tissue Growth Factor Measured Using a Biosensor

2002 • 51 citations

The novel Streptomyces olivaceoviridis ABC transporter Ngc mediates uptake of N-acetylglucosamine and N,N'-diacetylchitobiose

2002 • 51 citations

Comparative thermodynamics for monomer and dimer sequence-dependent binding of a heterocyclic dication in the DNA minor groove

2002 • 51 citations

A plasmid system for optimization of Fab′ production in Escherichia coli: importance of balance of heavy chain and light chain synthesis

2002 • 51 citations

Preparation of Multilayers Containing Conjugated Thiophene-Based Polyelectrolytes. Layer-by-Layer Assembly and Viscoelastic Properties

2002 • 51 citations

Evidence for a Copper-Binding Superfamily of the Amyloid Precursor Protein

2002 • 51 citations

Activation-induced Conformational Changes in the I Domain Region of Lymphocyte Function-associated Antigen 1

2002 • 51 citations

Functional Specific Binding of Testosterone toSchistosoma haematobium28-Kilodalton GlutathioneS-Transferase

2002 • 51 citations

Immunogenicity of rDNA-derived pharmaceuticals

2002 • 50 citations

2‘-O-Methyl-RNA Hairpins Generate Loop−Loop Complexes and Selectively Inhibit HIV-1 Tat-Mediated Transcription

2002 • 50 citations

A MecA Paralog, YpbH, Binds ClpC, Affecting both Competence and Sporulation

2002 • 50 citations

PDZ Domains Facilitate Binding of High Temperature Requirement Protease A (HtrA) and Tail-specific Protease (Tsp) to Heterologous Substrates through Recognition of the Small Stable RNA A (ssrA)-encoded Peptide

2002 • 49 citations

Characterization and multiple molecular forms of TorD from Shewanella massilia, the putative chaperone of the molybdoenzyme TorA

2002 • 49 citations

Surface plasmon resonance biosensors

2007 • 49 citations

Dissociation of the Tubulin Dimer Is Extremely Slow, Thermodynamically Very Unfavorable, and Reversible in the Absence of an Energy Source

2002 • 49 citations

Interactions of the Type III Secretion Pathway Proteins LcrV and LcrG from Yersinia pestis Are Mediated by Coiled-Coil Domains

2002 • 49 citations

SITE-SPECIFIC INTERACTION OF BONE MORPHOGENETIC PROTEIN 2 WITH PROCOLLAGEN II

2002 • 49 citations

Small Molecule Ligands Define a Binding Site on the Immune Regulatory Protein B7.1

2002 • 49 citations

Emerging array-based technologies in proteomics

2002 • 49 citations

Suppression of Experimental Autoimmune Encephalomyelitis Using Peptide Mimics of CD28

2002 • 48 citations

Effective Rate Models for Receptors Distributed in a Layer above a Surface: Application to Cells and Biacore

2002 • 48 citations

Stable “zeta” peptides that act as potent antagonists of the high-affinity IgE receptor

2002 • 48 citations

Casein Interactions Studied by the Surface Plasmon Resonance Technique

2002 • 48 citations

Structure-Activity Analysis of the Purine Binding Site of Human Liver Glycogen Phosphorylase

2002 • 48 citations

Interaction of plasminogen activator inhibitor type‐1 (PAI‐1) with vitronectin

2002 • 47 citations

Phage-Display Selection of a Human Single-Chain Fv Antibody Highly Specific for Melanoma and Breast Cancer Cells Using a Chemoenzymatically Synthesized G_M3−Carbohydrate Antigen

2002 • 47 citations

Cortex mori extract induces cancer cell apoptosis through inhibition of microtubule assembly

2002 • 47 citations

Direct Versus Competitive Biosensor Immunoassays for the Detection of (Dihydro)Streptomycin Residues in Milk

2002 • 46 citations

The RuvABC resolvasome

2002 • 46 citations

Surface plasmon resonance-based competition assay to assess the sera reactivity of variants of humanized antibodies

2002 • 46 citations

Evaluation of progesterone-ovalbumin conjugates with different length linkers in enzyme-linked immunosorbant assay and surface plasmon resonance-based immunoassay

2002 • 46 citations

Synthesis and Self-Assembly of Globotriose Derivatives: A Model System for Studies of Carbohydrate−Protein Interactions

2002 • 46 citations

Direct kinetic assay of interactions between small peptides and immobilized antibodies using a surface plasmon resonance biosensor

2002 • 45 citations

Sequence Plasticity in the Antigen-binding Site of a Therapeutic Anti-HER2 Antibody

2002 • 45 citations

Rapid parallel mutation scanning of gene fragments using a microelectronic protein-DNA chip format

2002 • 45 citations

The Solution Structure and Intramolecular Associations of the Tec Kinase Src Homology 3 Domain

2002 • 44 citations

Oligomerization-dependent Association of the SAM Domains from Schizosaccharomyces pombe Byr2 and Ste4

2002 • 44 citations

Molecular immunolabeling with recombinant single-chain variable fragment (scFv) antibodies designed with metal-binding domains

2001 • 44 citations

Loop–loop interaction of HIV-1 TAR RNA with N3′ → P5′ deoxyphosphoramidate aptamers inhibits in vitro Tat-mediated transcription

2002 • 44 citations

Psathyrella velutina Mushroom Lectin Exhibits High Affinity toward Sialoglycoproteins Possessing TerminalN-Acetylneuraminic Acid α2,3-Linked to Penultimate Galactose Residues of Trisialyl N-Glycans

2002 • 44 citations

Characterization and potential function of a novel testis‐specific nucleoporin BS‐63

2001 • 43 citations

An antibody-calmodulin fusion protein reveals a functional dependence between macromolecular isoelectric point and tumor targeting performance

2002 • 43 citations

Identification of a Binding Site for Ganglioside on the Receptor Binding Domain of Tetanus Toxin

2002 • 43 citations

A novel, anchorless streptococcal surface protein that binds to human immunoglobulins

2002 • 43 citations

A single WW domain is the predominant mediator of the interaction between the human ubiquitin-protein ligase Nedd4 and the human epithelial sodium channel

2002 • 43 citations

DNA sequence recognition by the indolocarbazole antitumor antibiotic AT2433-B1 and its diastereoisomer

2002 • 43 citations

Identification of Ribosome-binding Protein p34 as an Intracellular Protein That Binds Acidic Fibroblast Growth Factor

2002 • 43 citations

Application of an Absorption-Based Surface Plasmon Resonance Principle to the Development of SPR Ammonium Ion and Enzyme Sensors

2002 • 42 citations

Mechanism of Interaction between Leucine-based Sorting Signals from the Invariant Chain and Clathrin-associated Adaptor Protein Complexes AP1 and AP2

2002 • 42 citations

Biochemical Characterization of the Human RAD51 Protein

2002 • 42 citations

Electrostatic and Hydrophobic Forces Tether the Proximal Region of the Angiotensin II Receptor (AT_1A) Carboxyl Terminus to Anionic Lipids

2002 • 42 citations

Effect of hydrogel matrix on binding kinetics of protein–protein interactions on sensor surface

2002 • 41 citations

Temperature differentially affects encounter and docking thermodynamics of antibody–antigen association

2002 • 41 citations

The impact of protein biochips and microarrays on the drug development process

2002 • 41 citations

A New Antibody Recognizing the vIII Mutation of Human Epidermal Growth Factor Receptor

2002 • 41 citations

Two classes of germline genes both derived from the VH1 family direct the formation of human antibodies that recognize distinct antigenic sites in the C2 domain of factor VIII

2002 • 41 citations

Plasticity in structure and interactions is critical for the action of indolicidin, an antibacterial peptide of innate immune origin

2002 • 41 citations

The cleavage site of C5 from man and animals as a common target for neutralizing human monoclonal antibodies: in vitro and in vivo studies

2002 • 41 citations

Lipid-restricted recognition of mycobacterial lipoglycans by human pulmonary surfactant protein A: a surface-plasmon-resonance study

2002 • 40 citations

Several regions of the repeat domain of theStaphylococcus capraeautolysin, AtlC, are involved in fibronectin binding

2002 • 40 citations

Affinity-capture reagents for protein arrays

2002 • 40 citations

FGF-18 is a neuron-derived glial cell growth factor expressed in the rat brain during early postnatal development

2002 • 40 citations

Miniature surface-plasmon resonance immunosensors - rapid and repetitive procedure

2002 • 40 citations

Cancer-associated Cleavage of Cytokeratin 8/18 Heterotypic Complexes Exposes a Neoepitope in Human Adenocarcinomas

2002 • 40 citations

A Thermodynamic Characterization of the Binding of Thrombin Inhibitors to Human Thrombin, Combining Biosensor Technology, Stopped-Flow Spectrophotometry, and Microcalorimetry

2002 • 40 citations

Analysis of the Role of the Interleukin-2 Receptor γ Chain in Ligand Binding

2002 • 40 citations

Characterization of a Novel and Functional Human Prolactin Receptor Isoform (ΔS1PRLr) Containing Only One Extracellular Fibronectin-Like Domain

2002 • 40 citations

Interaction of POB1, a Downstream Molecule of Small G Protein Ral, with PAG2, a Paxillin-binding Protein, Is Involved in Cell Migration

2002 • 40 citations

Altered Amelogenin Self-assembly Based on Mutations Observed in Human X-linked Amelogenesis Imperfecta (AIH1)

2002 • 40 citations

Two Distinct Domains of Protein 4.1 Critical for Assembly of Functional Nuclei in Vitro

2002 • 40 citations

Transcriptional Regulation by Antitermination. Interaction of RNA with NusB Protein and NusB/NusE Protein Complex of Escherichia coli

2002 • 39 citations

Study of substrate–enzyme interaction between immobilized pyridoxamine and recombinant porcine pyridoxal kinase using surface plasmon resonance biosensor

2002 • 39 citations

Quantification of the Influence of HPrSer46P on CcpA–cre Interaction

2002 • 39 citations

Recognition of Tmiddle dotG mismatched base pairs in DNA by stacked imidazole-containing polyamides: surface plasmon resonance and circular dichroism studies

2002 • 39 citations

Petasiphenol: A DNA Polymerase λ Inhibitor

2002 • 39 citations

Identification and characterization of AGTRAP, a human homolog of murine Angiotensin II Receptor-Associated Protein (Agtrap)

2002 • 38 citations

Formation of Tethered and Streptavidin-Supported Lipid Bilayers on a Microporous Electrode for the Reconstitution of Membranes of Large Surface Area

2002 • 38 citations

Formation of Complexes between Ca2+·Calmodulin and the Synapse-associated Protein SAP97 Requires the SH3 Domain-Guanylate Kinase Domain-connecting HOOK Region

2002 • 38 citations

A directional nucleation-zipping mechanism for triple helix formation

2002 • 38 citations

In Situ Investigation of Adlayer Formation and Adsorption Kinetics of Amphiphilic Surface-Block Dendrimers on Solid Substrates

2002 • 38 citations

Strategic Use of Affinity-Based Mass Spectrometry Techniques in the Drug Discovery Process

2001 • 38 citations

Neoglycoconjugates of Mannan with Bovine Serum Albumin and Their Interaction with Lectin Concanavalin A

2001 • 38 citations

Increased Affinity and Stability of an Anti-HIV-1 Envelope Immunotoxin by Structure-based Mutagenesis

2002 • 38 citations

Characterization of the vascular endothelial growth factor–receptor interaction and determination of the recombinant protein by an optical receptor sensor

2002 • 38 citations

Binding of protegrin-1 to Pseudomonas aeruginosa and Burkholderia cepacia

2002 • 37 citations

Dynamic Localization/Association of Protein Kinase CK2 Subunits in Living Cells

2002 • 37 citations

Surface plasmon resonance and free oscillation rheometry in combination: a useful approach for studies on haemostasis and interactions between whole blood and artificial surfaces

2002 • 37 citations

Biochemical Properties of Single-Stranded DNA-Binding Protein from Mycobacterium smegmatis, a Fast-growing Mycobacterium and Its Physical and Functional Interaction with Uracil DNA Glycosylases

2002 • 37 citations

Probing T cell membrane organization using dimeric MHC–Ig complexes

2002 • 37 citations

High affinity binding of long-chain polysialic acid to antibody, and modulation by divalent cations and polyamines

2002 • 37 citations

Functional Analysis of Cdc42 Residues Required for Guanine Nucleotide Exchange

2002 • 37 citations

A Discrete Domain of the Human TrkB Receptor Defines the Binding Sites for BDNF and NT-4

2002 • 37 citations

Neuropeptide AF and FF Modulation of Adipocyte Metabolism

2002 • 37 citations

FAP52 Regulates Actin Organization via Binding to Filamin

2002 • 37 citations

Epitope mapping of the O‐chain polysaccharide of Legionella pneumophila serogroup 1 lipopolysaccharide by saturation‐transfer‐difference NMR spectroscopy

2002 • 36 citations

Making Sense of the Diverse Ligand Recognition by NKG2D

2002 • 36 citations

Clustered Charged Amino Acids of Human Adenosine Deaminase Comprise a Functional Epitope for Binding the Adenosine Deaminase Complexing Protein CD26/Dipeptidyl Peptidase IV

2002 • 36 citations

Interaction of Hsp90 with 20S proteasome: Thermodynamic and kinetic characterization

2002 • 36 citations

Analysis of_β-Lactam Antibiotics Using a Microbial Receptor Protein-based Biosensor Assay

2002 • 36 citations

FKBP12 Modulation of the Binding of the Skeletal Ryanodine Receptor onto the II-III Loop of the Dihydropyridine Receptor

2002 • 36 citations

The “Cap-Binding Slot” of an mRNA Cap-Binding Protein: Quantitative Effects of Aromatic Side Chain Choice in the Double-Stacking Sandwich with Cap^,

2002 • 36 citations

QSAR studies applied to the prediction of antigen–antibody interaction kinetics as measured by BIACORE

2002 • 36 citations

Development of a biosensor-based method for detection and isotyping of antibody responses to adenoviral-based gene therapy vectors

2002 • 36 citations

Quantifying the Energetics of Cooperativity in a Ternary Protein Complex

2002 • 36 citations

Novel anti-CD30 recombinant immunotoxins containing disulfide-stabilized Fv fragments.

2002 • 36 citations

Transport and Kinetic Processes Underlying Biomolecular Interactions in the BIACORE Optical Biosensor

2002 • 35 citations

Platelet-derived Growth Factor-BB and Basic Fibroblast Growth Factor Directly Interact in Vitro with High Affinity

2002 • 35 citations

Mapping of a hapten-binding site: molecular modeling and site-directed mutagenesis study of an anti-atrazine antibody

2002 • 35 citations

Confined and Vented Ethylene/Air Deflagrations at Initially Elevated Pressures and Turbulence Levels

2002 • 35 citations

Fab-scFv fusion protein: an efficient approach to production of bispecific antibody fragments

2002 • 35 citations

Determination of ivermectin in bovine liver by optical immunobiosensor

2002 • 35 citations

Structural Plasticity and Noncovalent Substrate Binding in the GroEL Apical Domain

2002 • 35 citations

Replacement of the Intervening Amino Acid Sequence of a Syk-Binding Diphosphopeptide by a Nonpeptide Spacer with Preservation of High Affinity

2002 • 35 citations

Interactions between the juxtamembrane domain of the EGFR and calmodulin measured by surface plasmon resonance

2002 • 34 citations

A Branched Peptide Mimotope of the Nicotinic Receptor Binding Site Is a Potent Synthetic Antidote against the Snake Neurotoxin α-Bungarotoxin

2002 • 34 citations

Targeting of Human Breast Cancer by a Bispecific Antibody Directed against Two Tumour-Associated Antigens: ErbB-2 and Carcinoembryonic Antigen

2002 • 34 citations

Biological Properties of N-Acyl and N-Haloacetyl Neuraminic Acids: Processing by Enzymes of Sialic Acid Metabolism, and Interaction with Influenza Virus

2002 • 34 citations

Characterization of oxidoreductase–redox polymer electrostatic film assembly on gold by surface plasmon resonance spectroscopy and Fourier transform infrared–external reflection spectroscopy

2002 • 34 citations

Structural Requirements for High-Affinity Heparin Binding: Alanine Scanning Analysis of Charged Residues in the C-Terminal Domain of Human Extracellular Superoxide Dismutase

2002 • 34 citations

Crystal Structure of the Ly49I Natural Killer Cell Receptor Reveals Variability in Dimerization Mode Within the Ly49 Family

2002 • 34 citations

Identification of the Disulfide Bonds in the Recombinant Somatomedin B Domain of Human Vitronectin

2002 • 34 citations

Analysis of the binding of bispecific monoclonal antibodies with immobilized antigens (human IgG and horseradish peroxidase) using a resonant mirror biosensor

2002 • 33 citations

Characterization and Comparative Evaluation of a Novel PAI-1 Inhibitor

2002 • 33 citations

Studies on the relevance of the glycan at Asn-52 of the α-subunit of human chorionic gonadotropin in the αβ dimer

2002 • 33 citations

Preparation of recombinant MK-1/Ep-CAM and establishment of an ELISA system for determining soluble MK-1/Ep-CAM levels in sera of cancer patients

2002 • 33 citations

Effects of deletion of streptokinase residues 48–59 on plasminogen activation

2002 • 33 citations

Porcine Pancreatic α-Amylase Shows Binding Activity towardN-Linked Oligosaccharides of Glycoproteins

2002 • 33 citations

Engineering-Specific Pharmacological Binding Sites for Peptidyl Inhibitors of Potassium Channels into KcsA

2002 • 33 citations

Molecular Structure and Novel DNA Binding Sites Located in Loops of Flap Endonuclease-1 from Pyrococcus horikoshii

2002 • 33 citations

The size, shape and specificity of the sugar-binding site of the jacalin-related lectins is profoundly affected by the proteolytic cleavage of the subunits

2002 • 33 citations

Mechanism of the regulation of type IB phosphoinositide 3OH-kinase byG-protein βγ subunits

2002 • 33 citations

Grafting of “Abbreviated” Complementarity-Determining Regions Containing Specificity-Determining Residues Essential for Ligand Contact to Engineer a Less Immunogenic Humanized Monoclonal Antibody

2002 • 33 citations

The Chaperone Activity of Protein Disulfide Isomerase Is Affected Cyclophilin B and Cyclosporin A In Vitro

2002 • 32 citations

Cutting Edge: The Minor Histocompatibility Antigen H60 Peptide Interacts with Both H-2Kb and NKG2D

2002 • 32 citations

Evidence that Phospholipids Play a Key Role in Pre-β ApoA-I Formation and High-Density Lipoprotein Remodeling^†

2002 • 32 citations

Structure of an Anti-blood Group A Fv and Improvement of Its Binding Affinity without Loss of Specificity

2002 • 32 citations

Improved method for pepsinolysis of mouse IgG1 molecules to F(ab′)2 fragments

2002 • 32 citations

Isolation of receptor–ligand pairs by capture of long-lived multivalent interaction complexes

2002 • 32 citations

Type I collagen contains at least 14 cryptic fibronectin binding sites of similar affinity

2002 • 32 citations

Does fusion of domains from unrelated proteins affect their folding pathways and the structural changes involved in their function? A case study with the diphtheria toxin T domain

2002 • 32 citations

Ligands for murine NKG2D display heterogeneous binding behavior

2002 • 32 citations

Rational design of green fluorescent protein mutants as biosensor for bacterial endotoxin

2002 • 32 citations

Deletions in the loop surrounding the iron–sulfur cluster of adrenodoxin severely affect the interactions with its native redox partners adrenodoxin reductase and cytochrome P450scc (CYP11A1)

2002 • 32 citations

A single WW domain is the predominant mediator of the interaction between the human ubiquitin-protein ligase Nedd4 and the human epithelial sodium channel

2002 • 32 citations

Genomic Effects of Polyamide/DNA Interactions on mRNA Expression

2002 • 31 citations

Equilibrium and Kinetic Analyses of the Interactions between Vitamin B12 Binding Proteins and Cobalamins by Surface Plasmon Resonance

2002 • 31 citations

Prohibitin and prohibitone are contained in high-molecular weight complexes and interact with α-actinin and annexin A2

2002 • 31 citations

Characterization of a Conformationally Sensitive Murine Monoclonal Antibody Directed to the Metal Ion-Dependent Adhesion Site Face of Integrin CD11b

2002 • 31 citations

Identification of Human Mannose Binding Lectin (MBL) Recognition Sites for Novel Inhibitory Antibodies

2002 • 31 citations

A Human Immunoglobulin G1 Antibody Originating from an in Vitro-Selected Fab Phage Antibody Binds Avidly to Tumor-Associated MUC1 and Is Efficiently Internalized

2002 • 31 citations

Kinetic study of various binding modes between human DNA polymerase β and different DNA substrates by surface-plasmon-resonance biosensor

2002 • 31 citations

Designed, Folded Polypeptide Scaffolds That Combine Key Biosensing Events of Recognition and Reporting

2002 • 31 citations

Rapid Progression to Simian AIDS Can Be Accompanied by Selection of CD4-Independent gp120 Variants with Impaired Ability To Bind CD4

2002 • 31 citations

Cell membrane hybrid bilayers containing the G-protein-coupled receptor CCR5

2002 • 31 citations

Spatial and Temporal Regulation of Tenascin-R Glycosylation in the Cerebellum

2002 • 30 citations

The Connecting Segment between Both Epidermal Growth Factor-like Domains in Blood Coagulation Factor IX Contributes to Stimulation by Factor VIIIa and Its Isolated A2 Domain

2002 • 30 citations

Supramolecular Formation of Antibodies with Viologen Dimers: Utilization for Amplification of Methyl Viologen Detection Signals in Surface Plasmon Resonance Sensor

2002 • 30 citations

Characterization of heparin binding by a peptide from amyloid P component using capillary electrophoresis, surface plasmon resonance and isothermal titration calorimetry

2002 • 30 citations

Use of biosensors to monitor the immune response.

2002 • 30 citations

Functional epitope of common γ chain for interleukin‐4 binding

2002 • 30 citations

Complex role of the β2-β3 Loop in the Interaction of U1A with U1 Hairpin II RNA

2002 • 30 citations

Ligand Binding Sites of Inducible Costimulator and High Avidity Mutants with Improved Function

2002 • 30 citations

DNA Binding and Topoisomerase I Poisoning Activities of Novel Disaccharide Indolocarbazoles

2002 • 30 citations

Structural Requirements of Anticoagulant Protein S for Its Binding to the Complement Regulator C4b-binding Protein

2002 • 30 citations

Influence of mannan epitopes in glycoproteins–Concanavalin A interaction. Comparison of natural and synthetic glycosylated proteins

2002 • 30 citations

A Surface Plasmon Resonance Analysis of the Interaction between the Antibiotic Moenomycin A and Penicillin-Binding Protein 1b

2002 • 30 citations

High Affinity Xenoreactive TCR:MHC Interaction Recruits CD8 in Absence of Binding to MHC

2003 • 29 citations

Artificial DNA-Bending Six-Zinc Finger Peptides with Different Charged Linkers: Distinct Kinetic Properties of DNA Bindings

2002 • 29 citations

An RNA Complex of the HIV-1 A-Loop and tRNA^Lys,3 Is Stabilized by Nucleoside Modifications

2002 • 29 citations

Structural Requirements for Interactions between Leucine-sorting Signals and Clathrin-associated Adaptor Protein Complex AP3

2002 • 29 citations

Involvement of a Nine-residue Loop of Streptokinase in the Generation of Macromolecular Substrate Specificity by the Activator Complex through Interaction with Substrate Kringle Domains

2002 • 29 citations

Kinetic Analysis of the Interactions between Troponin C and the C-terminal Troponin I Regulatory Region and Validation of a New Peptide Delivery/Capture System used for Surface Plasmon Resonance

2002 • 28 citations

Rapid analysis of protein interactions: On-chip micropurification of recombinant protein expressed in Esherichia coli

2002 • 28 citations

Human vascular endothelial growth factor B: Characterization of recombinant isoforms and generation of neutralizing monoclonal antibodies

2002 • 28 citations

Mutations in the CCGTTCACA DnaA Box of Mycobacterium tuberculosis oriC That Abolish Replication of oriC Plasmids Are Tolerated on the Chromosome

2002 • 28 citations

Peptide-Independent Folding and CD8αα Binding by the Nonclassical Class I Molecule, Thymic Leukemia Antigen

2002 • 28 citations

The GTP-Dependent Restriction Enzyme McrBC fromEscherichia coliForms High-Molecular Mass Complexes with DNA and Produces a Cleavage Pattern with a Characteristic 10-Base Pair Repeat

2002 • 28 citations

A novel mechanism for inhibition of HIV-1 reverse transcriptase

2002 • 28 citations

A SURFACE PLASMON RESONANCE BIOSENSOR FOR THE DETERMINATION OF THE AFFINITY OF DRUGS FOR NUCLEIC ACIDS

2002 • 28 citations

Essential Amino Acid Residues in the Single-stranded DNA-binding Protein of Bacteriophage T7

2002 • 28 citations

The characterization of biomolecular secondary structures by surface plasmon resonance

2002 • 28 citations

Surface Plasmon Resonance Biosensors

2002 • 28 citations

Peptide-protein interactions studied by surface plasmon and nuclear magnetic resonances

2001 • 27 citations

Activation of microsomal epoxide hydrolase by interaction with cytochromes P450: kinetic analysis of the association and substrate-specific activation of epoxide hydrolase function

2002 • 27 citations

Modular Arrangement and Secretion of a Multidomain Serine Protease

2002 • 27 citations

A New Family of Phosphotransferases with a P-loop Motif

2002 • 27 citations

Functional Promiscuity of Squirrel Monkey Growth Hormone Receptor Toward both Primate and Nonprimate Growth Hormones

2002 • 27 citations

In Vivo Modifications of Small GTPase Rac and Cdc42 by Bordetella Dermonecrotic Toxin

2002 • 27 citations

β-Turn Phe in HIV-1 Env Binding Site of CD4 and CD4 Mimetic Miniprotein Enhances Env Binding Affinity but Is Not Required for Activation of Co-Receptor/17b Site

2002 • 26 citations

Analysis of Cre–loxP interaction by surface plasmon resonance: Influence of spermidine on cooperativity

2002 • 26 citations

Reversible Surface Thiol Immobilization of Carboxyl Group Containing Haptens to a BIAcore Biosensor Chip Enabling Repeated Usage of a Single Sensor Surface

2002 • 26 citations

Oligolysine-based saccharide clusters: synthesis and specificity

2002 • 26 citations

Identification of Key Amino Acid Residues in the Assembly of Enzymes into the Pyruvate Dehydrogenase Complex of Bacillus stearothermophilus: A Kinetic and Thermodynamic Analysis

2002 • 26 citations

Surface plasmon resonance of electrochemically deposited Au-black

2002 • 26 citations

Arg–Cys and Arg–cysteamine adsorbed on gold and the G-protein–adsorbate interaction

2002 • 26 citations

A Novel Fluorescent Protein-Based Biosensor for Gram-Negative Bacteria

2002 • 25 citations

Covalent modification of proteins by cocaine

2002 • 25 citations

Role of Zymogenicity-Determining Residues of Coagulation Factor VII/VIIa in Cofactor Interaction and Macromolecular Substrate Recognition

2002 • 25 citations

Biochemical Characterization of Two Analogues of the Apoptosis-linked Gene 2 Protein in Dictyostelium discoideumand Interaction with a Physiological Partner in Mammals, Murine Alix

2002 • 25 citations

Early-glycation of apolipoprotein E: effect on its binding to LDL receptor, scavenger receptor A and heparan sulfates

2002 • 25 citations

Ciglitazone Inhibits Plasmin-Induced Proinflammatory Monocyte Activation via Modulation of p38 MAP Kinase Activity

2002 • 25 citations

Immobilized Small Deoxyribozyme to Distinguish RNA Secondary Structures

2002 • 25 citations

Affinity analysis of lectin interaction with immobilized C- and O- gylcosides studied by surface plasmon resonance assay

2002 • 25 citations

Polydispersity of Bacillus thuringiensis Cry1 toxins in solution and its effect on receptor binding kinetics

2002 • 25 citations

Biosensor analysis of dynamics of interleukin 5 receptor subunit βc interaction with IL5:IL5Rα complexes

2002 • 25 citations

Evidence against a Simple Tethering Model for Enhancement of Herpes Simplex Virus DNA Polymerase Processivity by Accessory Protein UL42

2002 • 25 citations

Arginine Operator Binding by Heterologous and Chimeric ArgR Repressors from Escherichia coli and Bacillus stearothermophilus

2002 • 25 citations

Development of a confined wall-jet flow-through cell for simultaneous electrochemical and surface plasmon resonance applications

2002 • 24 citations

Analysis of glycoproteins in cell culture supernatants using a lectin immunosensor technique

2002 • 24 citations

Enhanced surface plasmon resonance immunoassay for human complement factor 4

2002 • 24 citations

Identification of extrinsic blood coagulation pathway inhibitors from the tick Ornithodoros savignyi (Acari: Argasidae)

2002 • 24 citations

The Helix-Turn-Helix Motif of the Coliphage 186 Immunity Repressor Binds to Two Distinct Recognition Sequences

2002 • 24 citations

Single-chain Vascular Endothelial Growth Factor Variant with Antagonist Activity

2002 • 24 citations

A Surface Plasmon Resonance Analysis of the Interaction between the Antibiotic Moenomycin A and Penicillin‐Binding Protein 1b

2002 • 24 citations

Evolutionary Affinity and Selectivity Optimization of a Pesticide-Selective Antibody Utilizing a Hapten-Selective Immunoglobulin Repertoire

2002 • 24 citations

Necessity of the stalk region for immunoglobulin E interaction with CD23

2002 • 23 citations

Reduction of Sample Matrix Effects - The Analysis of Benzimidazole Residues in Serum by Immunobiosensor

2002 • 23 citations

Metabolic Channeling of Carbamoyl Phosphate, a Thermolabile Intermediate

2002 • 23 citations

A de Novo Designed Template for Generating Conformation-specific Antibodies That Recognize α-Helices in Proteins

2002 • 23 citations

The 99 and 170 Loop-modified Factor VIIa Mutants Show Enhanced Catalytic Activity without Tissue Factor

2002 • 23 citations

Assay and screening methods for bioactive substances based on cellular signaling pathways

2002 • 23 citations

Mapping the Epitope of an Inhibitory Monoclonal Antibody to the C-terminal DNA-binding Domain of HIV-1 Integrase

2002 • 22 citations

Biosensor Immunoassay of Ivermectin in Bovine Milk

2002 • 22 citations

The α-Chains of C4b-binding Protein Mediate Complex Formation with Low Density Lipoprotein Receptor-related Protein

2002 • 22 citations

Characterization of the Interaction between DNA Gyrase Inhibitor and DNA Gyrase of Escherichia coli

2002 • 22 citations

Holliday junction binding and processing by the RuvA protein of Mycoplasma pneumoniae

2002 • 22 citations

Moenomycin-Mediated Affinity Purification of Penicillin-Binding Protein 1b

2002 • 22 citations

Human milk oligosaccharides: an enzymatic protection step simplifies the synthesis of 3′- and 6′-O-sialyllactose and their analogues

2002 • 22 citations

Use of a purified and functional recombinant calcium-channel β4 subunit in surface-plasmon resonance studies

2002 • 22 citations

Comparative properties of two peptide–antibody interactions as deduced from epitope delineation

2002 • 22 citations

Escherichia coli single‐stranded DNA‐binding protein, a molecular tool for improved sequence quality in pyrosequencing

2002 • 22 citations

Mycobacterium tuberculosis RecA Intein Possesses a Novel ATP-dependent Site-specific Double-stranded DNA Endonuclease Activity

2002 • 22 citations

Biophysical Characterization of Proteins in the Post-genomic Era of Proteomics

2002 • 22 citations

Bioengineering and characterization of DNA–protein assemblies floating on supported membranes

2001 • 21 citations

Ionic interaction of the HIV-1 V3 domain with CCR5 and deregulation of T lymphocyte function

2002 • 21 citations

Experimental and Calculated Shift in p K a upon Binding of Phosphotyrosine Peptide to the SH2 Domain of p56 lck

2002 • 21 citations

Design of buffer exchange surfaces and sensor chips for biosensor chip mass spectrometry

2002 • 21 citations

Characterization of von Willebrand Factor Interaction with Collagens in Real Time Using Surface Plasmon Resonance

2002 • 21 citations

A Spectroscopic and Surface Plasmon Resonance Study of Oleic Acid/DNA Complexes

2002 • 21 citations

The phosphotransferase system of Streptomyces coelicolor

2002 • 21 citations

Single-chain antibodies produced by phage display against the C-terminal 19 kDa region of merozoite surface protein-1 of Plasmodium yoelii reduce parasite growth following challenge

2002 • 21 citations

Electrochemical enzyme immunoassay using immobilized antibody on gold film with monitoring of surface plasmon resonance signal

2002 • 21 citations

Characterisation of antibodies and analytes by surface plasmon resonance for the optimisation of a competitive immunoassay based on energy transfer

2002 • 21 citations

A Three-domain Structure for the δ Subunit of the DNA Polymerase III Holoenzyme δ Domain III Binds δ′ and Assembles into the DnaX Complex

2002 • 21 citations

Purification and Characterization of Arginine Carboxypeptidase Produced by Porphyromonas gingivalis

2002 • 21 citations

N-Glycans Stabilize Human Erythropoietin through Hydrophobic Interactions with the Hydrophobic Protein Surface: Studies by Surface Plasmon Resonance Analysis

2002 • 21 citations

In vivo and in vitro evidence that cross-reactive antibodies to C-terminus of hypervariable region 1 do not neutralize heterologous hepatitis C virus

2002 • 20 citations

Interaction of glycophorin A with lectins as measured by surface plasmon resonance (SPR).

2002 • 20 citations

Effect of heparin chain length on the interaction with tissue factor pathway inhibitor (TFPI)

2002 • 20 citations

Characterization and epitope mapping of two monoclonal antibodies against human CD99

2002 • 20 citations

Intracellular Single-Chain Variable Fragments Directed to the Src Homology 2 Domains of Syk Partially Inhibit FcεRI Signaling in the RBL-2H3 Cell Line

2002 • 20 citations

Dissociation of the GroEL−GroES Asymmetric Complex Is Accelerated by Increased Cooperativity in ATP Binding to the GroEL Ring Distal to GroES

2002 • 20 citations

A talin fragment as an actin trap visualizing actin flow in chemotaxis, endocytosis, and cytokinesis

2002 • 20 citations

Production and characterisation of a recombinant scFv reactive with human gastrointestinal carcinomas

2002 • 20 citations

Detection and characterization of pediatric serum antibody to the OMP P5-homologous adhesin of nontypeable Haemophilus influenzae during acute otitis media

2002 • 20 citations

Bi-functional, Substrate Mimicking RNA Inhibits MSK1-mediated cAMP-response Element-binding Protein Phosphorylation and Reveals Magnesium Ion-dependent Conformational Changes of the Kinase

2002 • 20 citations

Electrochemical Deprotection for Site-Selective Immobilization of Biomolecules

2002 • 20 citations

Substitution in the Murine Nectin1 Receptor of a Single Conserved Amino Acid at a Position Distal from the Herpes Simplex Virus gD Binding Site Confers High-Affinity Binding to gD

2002 • 20 citations

Haptens and Monoclonal Antibodies for Immunoassay of Imidazolinone Herbicides

2002 • 20 citations

A divalent antibody format is required for neutralization of human cytomegalovirus via antigenic domain 2 on glycoprotein B

2002 • 20 citations

The binding of BmK abT, a unique neurotoxin, to mammal brain and insect Na+ channels using biosensor

2002 • 20 citations

Use of Optical Biosensor Technology to Study Immunological Cross-Reactivity between Different Sulfonamide Drugs

2002 • 19 citations

Transcriptional Regulation of the Rat Bradykinin B2 Receptor Gene: Identification of a Silencer Element

2002 • 19 citations

Novel Assays and Sensor Platforms for the Detection of Aflatoxins

2002 • 19 citations

Functional aspects of co‐variant surface charges in an antibody fragment

2002 • 19 citations

Protein Ser/Thr phosphatases PPEF interact with calmodulin

2002 • 19 citations

Interaction of Human DNA Topoisomerase II α with DNA: Quantification by Surface Plasmon Resonance

2002 • 19 citations

An In-Line Flow Injection Optical Biosensor for Real-Time Bioprocess Monitoring

2002 • 19 citations

An Alternative Method To Quantify Surface Plasmon Resonance Measurements of Adsorption on Flat Surfaces

2002 • 19 citations

Expression, mutagenesis and kinetic analysis of recombinant K1E endosialidase to define the site of proteolytic processing and requirements for catalysis

2002 • 19 citations

High-throughput screening in the diagnostics industry

2002 • 18 citations

Antibodies to Factor XII Are Distinct from Antibodies to Prothrombin in Patients with the Anti-phospholipid Syndrome

2002 • 18 citations

Escherichia coli single-stranded DNA-binding protein, a molecular tool for improved sequence quality in pyrosequencing.

2002 • 18 citations

Elimination of Ingredients Effect to Improve the Detection of Anti HIV-1 p24 Antibody in Human Serum Using SPR Apparatus

2002 • 18 citations

Differential clinical efficacy of anti-CD4 monoclonal antibodies in rat adjuvant arthritis is paralleled by differential influence on NF-κB binding activity and TNF-α secretion of T cells

2002 • 18 citations

Preparation of refractive index matching polymer film alternative to oil for use in a portable surface-plasmon resonance phenomenon-based chemical sensor method

2002 • 18 citations

A Mathematical Analysis Using Fractals for Binding Interactions of Nuclear Estrogen Receptors Occurring on Biosensor Surfaces

2002 • 18 citations

Functional Consequences of Insertions and Deletions in the Complementarity-determining Regions of Human Antibodies

2002 • 18 citations

The inhibitory region of troponin‐I alters the ability of F‐actin to interact with different segments of myosin

2002 • 18 citations

Development of Novel Tumor Imaging Agents with Phage-Display Combinatorial Peptide Libraries

2002 • 18 citations

Methods for generation of monoclonal antibodies to the very small drug hapten, 5-benzimidazolecarboxylic acid

2002 • 18 citations

Dematin interacts with the Ras‐guanine nucleotide exchange factor Ras‐GRF2 and modulates mitogen‐activated protein kinase pathways

2002 • 18 citations

Interaction of bovine coagulation factor X and its glutamic‐acid‐containing fragments with phospholipid membranes

2002 • 18 citations

Novel CD8+ T Cell Antagonists Based on β2-Microglobulin

2002 • 18 citations

Stimulation of Ca2+/calmodulin-dependent protein kinase phosphatase by polycations

2002 • 18 citations

Compensation for Loss of Ligand Activity in Surface Plasmon Resonance Experiments

2002 • 17 citations

Procollagen with Skipping of α1(I) Exon 41 Has Lower Binding Affinity for α1(I) C-telopeptide, Impaired in Vitro Fibrillogenesis, and Altered Fibril Morphology

2002 • 17 citations

Real-Time Analysis of Molecular Interaction of Retinoid Receptors and Receptor-Interacting Protein 140 (RIP140)

2002 • 17 citations

Characterization of autoantibodies from patients with Goodpasture's disease using a resonant mirror biosenso

2002 • 17 citations

A strategy for inducing an immune response against Androctonus australis scorpion venom toxin I in mice. Production of high-affinity monoclonal antibodies and their use in a sensitive two-site immunometric assay

2002 • 17 citations

Phage Display Based Cloning of Proteins Interacting with the Cytoplasmic Tail of Membrane Immunoglobulins

2002 • 17 citations

Targeting immune effector molecules to human tumor cells through genetic delivery of 5T4-specific scFv fusion proteins

2002 • 17 citations

Receptor-Based Antidote for Diphtheria

2002 • 17 citations

Structure-Based Design of a Leucine Zipper Protein with New DNA Contacting Region

2002 • 17 citations

Quantitation of intracellular recombinant human superoxide dismutase using surface plasmon resonance

2002 • 17 citations

Isoenzyme-directed selection and characterization of anti-creatine kinase single chain Fv antibodies from a human phage display library

2002 • 17 citations

Conformational solution studies of neuropeptide γ using CD and NMR spectroscopy

2002 • 17 citations

A novel aldehyde dextran sulfonate matrix for affinity biosensors

2002 • 16 citations

Analysis of the interaction between the aspartic peptidase inhibitor SQAPI and aspartic peptidases using surface plasmon resonance

2002 • 16 citations

Mimicry of Tandem Repeat Peptides against Cell Surface Carbohydrates

2002 • 16 citations

Species Specificity of Simian Virus 40 DNA Replication in Vitro Requires Multiple Functions of Human DNA Polymerase α

2002 • 16 citations

Differentiation of human serum samples by surface plasmon resonance monitoring of the integral glycoprotein interaction with a lectin panel

2002 • 16 citations

RNA Recognition by Transcriptional Antiterminators of the BglG/SacY Family: Mapping of SacY RNA Binding Site

2002 • 16 citations

Antiplasmin Activity of a Peptide That Binds to the Receptor-binding Site of Angiogenin

2002 • 16 citations

Examination of the kinetic mechanism of mitogen-activated protein kinase activated protein kinase-2

2002 • 16 citations

Unravelling Carbohydrate Interactions with Biosensors Using Surface Plasmon Resonance (SPR) Detection

2001 • 15 citations

Cloning, functional expression and kinetic characterization of pesticide-selective F ab fragment variants derived by molecular evolution of variable antibody genes

2002 • 15 citations

The N-terminal Epidermal Growth Factor-like Domain of Coagulation Factor IX

2002 • 15 citations

Array Optimization and Preprocessing Techniques for Chemical Sensing Microsystems

2002 • 15 citations

Expression and characterization of recombinant soluble human CD3 molecules: presentation of antigenic epitopes defined on the native TCR–CD3 complex

2002 • 15 citations

Inhibition of crotoxin phospholipase A2 activity by manoalide associated with inactivation of crotoxin toxicity and dissociation of the heterodimeric neurotoxic complex

2002 • 15 citations

Application of the small-angle x-ray scattering technique for the study of two-step equilibrium enzyme-substrate interactions

1998 • 15 citations

Elucidating Kinetic and Thermodynamic Constants for Interaction of G Protein Subunits and Receptors by Surface Plasmon Resonance Spectroscopy

2002 • 15 citations

Ca2+-dependent and phospholipid-independent binding of annexin 2 and annexin 5

2002 • 14 citations

Antibody Evolution from the Centre to the Periphery: Applied to a Human Antibody Fragment Recognising the Tumour-associated Antigen Mucin-1

2002 • 14 citations

The integrin β1 subunit cytoplasmic tail forms oligomers: a potential role in β1 integrin clustering

2002 • 14 citations

Genetic Organization of the Vibrio harveyi dnaA Gene Region and Analysis of the Function of the V. harveyi DnaA Protein in Escherichia coli

2002 • 14 citations

Dithio-Phospholipids for Biospecific Immobilization of Proteins on Gold Surfaces

2002 • 14 citations

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2002 • 14 citations

Testing the validity of the effective rate constant approximation for surface reaction with transport

2002 • 14 citations

In vitro molecular evolution of antibody genes mimicking receptor revision

2002 • 14 citations

Immunoassay for Serum Glutamine Synthetase in Serum: Development, Reference Values, and Preliminary Study in Dementias

2002 • 14 citations

Affinity of Stat2 for the Subunits of the Interferon Alpha Receptor

2002 • 14 citations

Interaction of Diocleinae Lectins with Glycoproteins Based in Surface Plasmon Resonance

2002 • 14 citations

Real-Time Kinetic Analyses of the Interaction of Ricin Toxin A-Chain with Ribosomes Prove a Conformational Change Involved in Complex Formation

2002 • 14 citations

Hydrophobic modifications at 1-phosphate of inositol 1,4,5-Trisphosphate analogues enhance receptor binding

2002 • 14 citations

Enhancing the Anticoagulant Potency of Soluble Tissue Factor Mutants by Increasing their Affinity to Factor VIIa

2002 • 14 citations

Characteristics of a Surface Plasmon Resonance Sensor Combined with a Poly(vinyl chloride) Film-based Ionophore Technique for Metal Ion Analyses

2002 • 14 citations

Novel peptide inhibitors for Grb2 SH2 domain and their detection by surface plasmon resonance

2002 • 13 citations

Molecular Motion of Electrically Stimulated Self-Assembled Monolayers on Gold Surface

2002 • 13 citations

Use of thiazolidine-mediated ligation for site specific biotinylation of mouse EGF for biosensor immobilisation

2001 • 13 citations

Functional mapping of conserved, surface‐exposed charges of antibody variable domains

2002 • 13 citations

Translation initiation and surface plasmon resonance: new technology applied to old questions

2002 • 13 citations

Cross communication between components of carbon catabolite repression of Lactobacillus casei and Bacillus megaterium.

2002 • 13 citations

Small ligands interacting with the phosphotyrosine binding pocket of the Src SH2 protein

2002 • 13 citations

Liver Targeting Liposomes Containing .BETA.-Sitosterol Glucoside with Regard to Penetration-Enhancing Effect on HepG2 Cells.

2002 • 13 citations

Positively Charged Amino Acids Are Essential for Electron Transfer and Protein−Protein Interactions in the Soluble Methane Monooxygenase Complex from Methylococcus capsulatus (Bath)

2002 • 13 citations

Focal Adhesion Protein FAP52 Self-Associates through a Sequence Conserved among the Members of the PCH Family Proteins

2002 • 12 citations

Probing functionalized gold colloids for single particle tracking experiments

2002 • 12 citations

Application of a Surface Plasmon Resonance Sensor to Analyses of Amine Compounds with the Use of a Polymer Film and an Acid-base Reaction

2002 • 12 citations

Development and characterization of a monoclonal antibody with cross-reactivity towards uracil and thymine, and its potential use in screening patients treated with 5-fluorouracil for possible risks

2002 • 12 citations

Methods of Analysis for Chemicals that Promote/Disrupt Cellular Signaling

2002 • 12 citations

Triterpenoid saponins stimulate the sugar taste receptor cell through a G protein-mediated mechanism in the blowfly, Phormia regina

2002 • 12 citations

Characterization of the Sperm Receptor for Acrosome Reaction-Inducing Substance of the Starfish, Asterias Amurensis

2002 • 12 citations

Amplification of Detection Signals for Methyl Viologen by Using Supramolecular Formation of Antibody with Viologen Dimer in Surface Plasmon Resonance Sensor

2002 • 12 citations

Peptides corresponding to gelsolin derived amyloid of the Finnish type (AGel_FIN) adopt two distinct forms in solution of which only one can polymerize into amyloid fibrils and form complexes with apoE

2002 • 12 citations

Determination of the turnover number of the restriction endonuclease EcoRI using evanescent wave technology

2002 • 11 citations

Insights into the Functioning of Bacillus subtilis HPr Kinase/Phosphatase: Affinity for Its Protein Substrates and Role of Cations and Phosphate

2002 • 11 citations

RAGE engagement and vascular cell derangement by short chain sugar-derived advanced glycation end products

2002 • 11 citations

Importance of an N-terminal extension in ribonuclease HII from Bacillus stearothermophilus for substrate binding

2002 • 11 citations

A kinetic study of analyte–receptor binding and dissociation for biosensor applications: a fractal analysis for cholera toxin and peptide–protein interactions

2002 • 11 citations

Surface plasmon resonance

2002 • 11 citations

Transition State Stabilization by the N-terminal Anticodon-binding Domain of Lysyl-tRNA Synthetase

2002 • 11 citations

Mutagenesis Within Human FcεRIα Differentially Affects Human and Murine IgE Binding

2002 • 11 citations

Binding Properties of Insulin-Like Growth Factor Binding Protein-3 (IGFBP-3), IGFBP-3 N- and C-Terminal Fragments, and Structurally Related Proteins mac25 and Connective Tissue Growth Factor Measured Using a Biosensor

2002 • 11 citations

Design and characterization of non-Phosphopeptide inhibitors for Src family SH2 domains

2002 • 10 citations

Comparative studies with surface plasmon resonance and free oscillation rheometry on the inhibition of platelets with cytochalasin E and monoclonal antibodies towards GPIIb/IIIa

2002 • 10 citations

Development and Applications of Surface Plasmon Resonance-Based von Willebrand Factor– Collagen Binding Assay

2002 • 10 citations

Involvement of carbohydrate molecules on zona pellucida in human fertilization

2002 • 10 citations

Analysis of Crystallin-Crystallin Interactions by Surface Plasmon Resonance.

2002 • 10 citations

Properties of cellulose-binding modules in endoglucanase F fromFibrobacter succinogenesS85 by means of surface plasmon resonance

2002 • 9 citations

The Resonant Mirror Optical Biosensor

2002 • 9 citations

Self-assembly of electron transport protein using oligonucleotide hybridization

2002 • 9 citations

Facile synthesis of stable lipid analogues possessing a range of alkyl groups: application to artificial glycolipids

2002 • 9 citations

Selection of human antibody fragments on the basis of stabilization of the variable domain in the presence of target antigens

2002 • 9 citations

Selection and characterisation of a phage-displayed human antibody (Fab) reactive to the lung resistance-related major vault protein

2002 • 9 citations

Characterization of monoclonal antibodies against Escherichia coli core RNA polymerase

2002 • 9 citations

In Vitro Scanning-Saturation Mutagenesis

2002 • 9 citations

Substrate-Induced Conformation of an Artificial Receptor with Two Receptor Sites

2002 • 9 citations

Specific interactions between cryogel components: role of extra domain A containing fibronectin in cryogelation

2002 • 9 citations

Molecular basis for different ability of low-density and high-density lipoproteins to support activity of the intrinsic Xase complex

2002 • 8 citations

Quantitative Estimation of Interaction between Carbohydrates and Concanavalin A by Surface Plasmon Resonance Biosensor.

2002 • 8 citations

On the Interaction of Ribosomal Protein L5 with 5S rRNA

2002 • 8 citations

Development of human antibody fragments directed towards synaptic acetylcholinesterase using a semi-synthetic phage display library

2002 • 8 citations

Biosensor detection of triplex formation by modified oligonucleotides

2002 • 8 citations

Development of monoclonal antibodies against creatine kinase MB2

2002 • 8 citations

Recombinant antibody Fab against the hypervariable region 1 of hepatitis C virus blocks the virus adsorption to susceptible cells in vitro

2002 • 8 citations

Surface plasmon resonance for measuring TBP–promoter interaction

2002 • 8 citations

Monoclonal anti‐diuron antibodies prevent inhibition of photosynthesis by diuron

2002 • 7 citations

Coiled coil miniprotein randomization on phage leads to charge pattern mimicry of the receptor recognition determinant of interleukin 5

2002 • 7 citations

Kinetics and Mechanism of Substitution Reactions between Myoglobin and Activated Self-Assembled Monolayers Investigated Using Surface Plasmon Resonance

2002 • 7 citations

A novel chemosensor system using surface plasmon resonance taste sensor and metal oxide odor sensor for quality control of vinegar

2002 • 7 citations

Binding of a C-Terminal Fragment (Residues 369 to 435) of Vitamin D-Binding Protein to Actin

2002 • 7 citations

The oligomeric state, complex formation, and chaperoning activity of Hsp70 and Hsp80 ofNeurospora crassa

2002 • 7 citations

Inhibition of angiogenesis by a monoclonal antibody to kininogen as well as by kininostatin which block proangiogenic high molecular weight kininogen

2002 • 7 citations

Distamycin A affects the stability of NF‐κB p50‐DNA complexes in a sequence‐dependent manner

2002 • 7 citations

A Single Amino Acid Difference between Human and Monkey Interleukin (IL)-1β Dictates Effective Binding to Soluble Type II IL-1 Receptor

2002 • 7 citations

Monoclonal antibodies raised against Xenopus p53 interact with human p73

2002 • 6 citations

Requirement for C-terminal Extension to the RNA Binding Domain for Efficient RNA Binding by Ribosomal Protein L2

2002 • 6 citations

Development of a new method to characterize (SMBV™) antigen formulations using surface plasmon resonance technology

2002 • 6 citations

Kinetic analysis of the interaction between the QutA and QutR transcription‐regulating proteins

2002 • 6 citations

Self-assembled plasmid DNA network prepared through both triple-helix formation and streptavidin–biotin interaction

2002 • 6 citations

Tissue Factor Alters the pK_a Values of Catalytically Important Factor VIIa Residues

2002 • 5 citations

Amplified Immunoassay of Human IgG Using Real‐time Biomolecular Interaction Analysis (BIA) Technology

2002 • 5 citations

Synthesis of tools for raising antibodies against moenomycin epitopes and initial immunological studies

2002 • 5 citations

Mutational Analysis of the Kinetics and Thermodynamics of Transcription Factor NF-κB Homodimerisation

2002 • 5 citations

Bivalency of plasminogen monoclonal antibodies is required for plasminogen bridging to fibrin and enhanced plasmin formation

2002 • 5 citations

Probing degeneracy in antigen–antibody recognition at the immunodominant site of foot‐and‐mouth disease virus

2002 • 5 citations

In vitro selection of RNA aptamers that bind to domain II of HCV IRES

2002 • 5 citations

Sequence-simplification and chimeric assembly: new models of peptide antigen modification

2002 • 5 citations

Cloning, expression, secondary structure characterization of HMG box 1 of hUBF from E. coli and its binding to DNA

2002 • 4 citations

A kinetic study of analyte–receptor binding and dissociation for biosensor applications: a fractal analysis for two different DNA systems

2002 • 4 citations

Understanding the puzzle of ‘well-characterized biotechnology products’

2002 • 4 citations

Determination of tyrosinase mRNA in melanoma by reverse transcription-PCR and optical mirror resonance biosensor

2002 • 4 citations

Identification of a novel AGE-capturable soluble variant of the RAGE in human sera

2002 • 3 citations

Importance of an N-Terminal Extension in Ribonuclease HII from Bacillus stearothermophilus for Substrate Binding

2002 • 3 citations

Structural analysis of chick ephrin-A2 by function-blocking and non-blocking monoclonal antibodies

2002 • 3 citations

Surface Plasmon Resonance of Calcium-Binding Proteins

2003 • 3 citations

Adding function to characterization: Combining mass spectrometry with surface plasmon resonance

2002 • 3 citations

DETECTION OF PYROGENS IN ULTRA-PURE WATER BY A SURFACE PLASMON RESONANCE BIOSENSOR

2002 • 3 citations

Selection of Antibodies Based on Antibody Kinetic Binding Properties

2003 • 2 citations

The Function of Dimeric Structure of Soluble Intercellular Adhesion Molecule-1 (sICAM-1)

2002 • 1 citations

Selective binding of nucleotide probes by eosinophilic cationic protein during in situ hybridisation.

2002 • 1 citations

Biosensors in the pharmaceutical and biomedical sciences

2002 • 1 citations

Real—time Analysis of the Interaction between Calmodulin and Melittin by SPR Spectroscopy

2002 • 1 citations

Binding analysis between naphthyridine dimers and GG mismatch DNA

2002 • 1 citations

[A structure-activity study of a catalytic antiidiotypic antibody to the human erythrocyte acetylcholinesterase].

2002 • 1 citations

Competence of Vimentin Mutants Having Deletion or Amino Acid Substitutions to Assemble into Intermediate Filaments

2002 • 1 citations

Deleted Work

1955 • 0 citations