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The Protein Data Bank

2000 • 35,287 citations

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1993 • 12,640 citations

Amino acid substitution matrices from protein blocks.

1992 • 5,998 citations

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1991 • 5,267 citations

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2001 • 3,629 citations

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1992 • 3,317 citations

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2000 • 1,494 citations

Lipids of mitochondria

1985 • 842 citations

C2-domains, Structure and Function of a Universal Ca2+-binding Domain

1998 • 835 citations

The C2 domain calcium‐binding motif: Structural and functional diversity

1996 • 784 citations

Asymmetrical Lipid Bilayer Structure for Biological Membranes

1972 • 606 citations

The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity

1997 • 436 citations

5-LIPOXYGENASE

1994 • 357 citations

Translocation of the 85-kDa Phospholipase A2 from Cytosol to the Nuclear Envelope in Rat Basophilic Leukemia Cells Stimulated with Calcium Ionophore or IgE/Antigen

1995 • 331 citations

Ca2+ bridges the C2 membrane-binding domain of protein kinase Cα directly to phosphatidylserine

1999 • 321 citations

Signaling and Subcellular Targeting by Membrane-Binding Domains

2000 • 259 citations

Electrostatic Control of the Membrane Targeting of C2 Domains

2002 • 222 citations

Membrane Targeting by C1 and C2 Domains

2001 • 218 citations

Role of Phosphorylation Sites and the C2 Domain in Regulation of Cytosolic Phospholipase A2

1999 • 207 citations

Structure of the key toxin in gas gangrene

1998 • 203 citations

The N-terminal Domain of 5-Lipoxygenase Binds Calcium and Mediates Calcium Stimulation of Enzyme Activity

2000 • 172 citations

Differential Roles of Ionic, Aliphatic, and Aromatic Residues in Membrane−Protein Interactions: A Surface Plasmon Resonance Study on Phospholipases A₂

2001 • 150 citations

Lipid-protein interactions in monolayers

1982 • 145 citations

A Structure-Function Study of the C2 Domain of Cytosolic Phospholipase A2

1999 • 137 citations

Independent Folding and Ligand Specificity of the C2 Calciumdependent Lipid Binding Domain of Cytosolic Phospholipase A2

1998 • 127 citations

Mapping the Phospholipid-binding Surface and Translocation Determinants of the C2 Domain from Cytosolic Phospholipase A2

1999 • 125 citations

Intracellular compartmentalization of leukotriene synthesis: unexpected nuclear secrets

2001 • 124 citations

Membrane Binding Assays for Peripheral Proteins

2001 • 123 citations

The N-terminal “β-Barrel” Domain of 5-Lipoxygenase Is Essential for Nuclear Membrane Translocation

2001 • 122 citations

Ca²⁺-Signaling Cycle of a Membrane-Docking C2 Domain

1997 • 117 citations

C2 Domains from Different Ca²⁺ Signaling Pathways Display Functional and Mechanistic Diversity

2001 • 112 citations

Membrane Targeting of C2 Domains of Phospholipase C-δ Isoforms

2002 • 91 citations

Cell Biology of the 5-Lipoxygenase Pathway

1998 • 86 citations

Interfacial membrane docking of cytosolic phospholipase A ₂ C2 domain using electrostatic potential-modulated spin relaxation magnetic resonance

1999 • 80 citations

Differential Membrane-Binding and Activation Mechanisms of Protein Kinase C-α and -ε

1998 • 79 citations

Location of the Membrane-Docking Face on the Ca²⁺-Activated C2 Domain of Cytosolic Phospholipase A₂

1998 • 79 citations

5-Lipoxygenase Binds Calcium

1999 • 73 citations

Characterisation of the calcium-binding C-terminal domain of Clostridium perfringens alpha-toxin 1 1Edited by A Klug

1999 • 62 citations

Roles of calcium ions in the membrane binding of C2 domains

2001 • 59 citations

Electrospray ionization mass spectrometry analyses of nuclear membrane phospholipid loss after reperfusion of ischemic myocardium

2000 • 51 citations

Roles of calcium ions in the membrane binding of C2 domains

2001 • 50 citations

Human 5-lipoxygenase associates with phosphatidylcholine liposomes and modulates LTA4 synthetase activity

1994 • 41 citations