Intranasal immunization with recombinant antigens associated with new cationic particles induces strong mucosal as well as systemic antibody and CTL responses

Correlates of Immune Protection Induced by Live, Attenuated, Cold‐Adapted, Trivalent, Intranasal Influenza Virus Vaccine

2000 • 408 citations

HIV-specific mucosal and cellular immunity in HIV-seronegative partners of HIV-seropositive individuals

1997 • 403 citations

DNA-based immunization induces continuous secretion of hepatitis B surface antigen and high levels of circulating antibody

1993 • 401 citations

HIV-1-Specific Mucosal CD8+ Lymphocyte Responses in the Cervix of HIV-1-Resistant Prostitutes in Nairobi

2000 • 379 citations

Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-gamma-dependent and -independent pathways.

1997 • 365 citations

Cutting Edge: The Mucosal Adjuvant Cholera Toxin Redirects Vaccine Proteins into Olfactory Tissues

2000 • 365 citations

Macrophagic myofasciitis lesions assess long-term persistence of vaccine-derived aluminium hydroxide in muscle

2001 • 353 citations

Cholera toxin induces maturation of human dendritic cells and licences them for Th2 priming

2000 • 285 citations

CpG DNA is a potent enhancer of systemic and mucosal immune responses against hepatitis B surface antigen with intranasal administration to mice.

1998 • 266 citations

Mucosal Delivery of Inactivated Influenza Vaccine Induces B-Cell-Dependent Heterosubtypic Cross-Protection against Lethal Influenza A H5N1 Virus Infection

2001 • 252 citations

Mucosal and Plasma IgA from HIV-1-Exposed Uninfected Individuals Inhibit HIV-1 Transcytosis Across Human Epithelial Cells

2000 • 245 citations

Cutting Edge: CpG DNA Is a Potent Enhancer of Systemic and Mucosal Immune Responses Against Hepatitis B Surface Antigen with Intranasal Administration to Mice

1998 • 223 citations

Intranasal Immunization with CpG Oligodeoxynucleotides as an Adjuvant Dramatically Increases IgA and Protection Against Herpes Simplex Virus-2 in the Genital Tract

2001 • 215 citations

T Lymphocytes Are Required for Protection of the Vaginal Mucosae and Sensory Ganglia of Immune Mice Against Reinfection with Herpes Simplex Virus Type 2

1998 • 194 citations

Secretory IgA Specific for a Conserved Epitope on gp41 Envelope Glycoprotein Inhibits Epithelial Transcytosis of HIV-1

2001 • 193 citations

A recombinant Salmonella typhimurium vaccine induces local immunity by four different routes of immunization

1995 • 179 citations

Immunization with a soluble recombinant HIV protein entrapped in biodegradable microparticles induces HIV-specific CD8+ cytotoxic T lymphocytes and CD4+ Th1 cells

1995 • 168 citations

Immunization with soluble hepatitis B virus surface protein elicits murine H-2 class I-restricted CD8+ cytotoxic T lymphocyte responses in vivo.

1994 • 165 citations

A mucosal vaccine against diphtheria: formulation of cross reacting material (CRM197) of diphtheria toxin with chitosan enhances local and systemic antibody and Th2 responses following nasal delivery

2000 • 154 citations

Mucosal Immunity to Influenza Without IgA: An IgA Knockout Mouse Model

1999 • 141 citations

Antibody-Independent Protective Mucosal Immunity to Gastric Helicobacter Infection in Mice

1999 • 140 citations

Lack of J Chain Inhibits the Transport of Gut IgA and Abrogates the Development of Intestinal Antitoxic Protection

1999 • 137 citations

A novel bioadhesive intranasal delivery system for inactivated influenza vaccines

2001 • 133 citations

IgA Deficiency**This article was accepted for publication on 17 January 1997.

1997 • 133 citations

Intranasal Monoclonal IgA Antibody to Respiratory Syncytial Virus Protects Rhesus Monkeys against Upper and Lower Respiratory Tract Infection

1996 • 130 citations

Monophosphoryl lipid A enhances mucosal and systemic immunity to vaccine antigens following intranasal administration

2000 • 130 citations

HIV-1 Neutralizing Antibodies in the Genital and Respiratory Tracts of Mice Intranasally Immunized with Oligomeric gp160

1998 • 112 citations

Bacterial Toxins as Mucosal Adjuvants

1999 • 102 citations

The induction of systemic and mucosal immune responses to antigen-adjuvant compositions administered into the skin: alterations in the migratory properties of dendritic cells appears to be important for stimulating mucosal immunity

2000 • 100 citations

IgA Immunodeficiency Leads to Inadequate Th Cell Priming and Increased Susceptibility to Influenza Virus Infection

2001 • 88 citations

Role of Mucosal Immunity in Herpes Simplex Virus Infection

1998 • 86 citations

Protection of the Villus Epithelial Cells of the Small Intestine from Rotavirus Infection Does Not Require Immunoglobulin A

2000 • 81 citations

Novel intranasal immunization techniques for antibody induction and protection of mice against gastric Helicobacter felis infection

1997 • 79 citations

Priming of cytotoxic T lymphocytes by five heat‐aggregated antigens in vivo: Conditions, efficiency, and relation to antibody responses

1997 • 75 citations

Protective Mucosal Immunity to Ocular Herpes Simplex Virus Type 1 Infection in Mice by UsingEscherichia coliHeat-Labile Enterotoxin B Subunit as an Adjuvant

2001 • 73 citations

Design, characterization and preclinical efficacy of a cationic lipid adjuvant for influenza split vaccine

2001 • 72 citations

Secretory Anti–Human Immunodeficiency Virus (HIV) Antibodies in Colostrum and Breast Milk Are Not a Major Determinant of the Protection of Early Postnatal Transmission of HIV

2000 • 70 citations

Intranasal immunization with liposome-formulated Yersinia pestis vaccine enhances mucosal immune responses

2000 • 69 citations

Genetically Manipulated Bacterial Toxin as a New Generation Mucosal Adjuvant

2001 • 68 citations

A Controlled Clinical Study of the Effect of Nasal Immunization with aStreptococcus mutansAntigen Alone or Incorporated into Liposomes on Induction of Immune Responses

1999 • 65 citations

Intranasal immunisation with influenza-ISCOM induces strong mucosal as well as systemic antibody and cytotoxic T-lymphocyte responses

2001 • 61 citations

Immunoglobulin A (IgA) Responses and IgE-Associated Inflammation along the Respiratory Tract after Mucosal but Not Systemic Immunization

2001 • 59 citations

Impairment of Mucosal Immunity by Total Parenteral Nutrition: Requirement for IgA in Murine Nasotracheal Anti-Influenza Immunity

2001 • 54 citations

Immunity to vaginal HSV‐2 infection in immunoglobulin A knockout mice

1998 • 53 citations

Characterisation and phase behaviour of phospholipid bilayers adsorbed on spherical polysaccharidic nanoparticles

1997 • 51 citations

Synthetic biomimetic supra molecular Biovector™ (SMBV™) particles for nasal vaccine delivery

2001 • 51 citations

Secretory Immunoglobulin A: from Mucosal Protection to Vaccine Development

1999 • 45 citations

Mucosal Immunology of the Upper Airways: An Overview^a

1997 • 39 citations

Mucosal and Systemic Immune Responses to Chimeric Fimbriae Expressed bySalmonella entericaSerovar Typhimurium Vaccine Strains

2000 • 36 citations

Alkyl–polyacrylate esters are strong mucosal adjuvants

2000 • 35 citations

Mucosal immunity and viral infections

2001 • 33 citations

Mucosal Immunity in the Genital Tract: Prospects for Vaccines Against Sexually Transmitted Diseases—A Review

1999 • 33 citations

Interleukin 12 and innate molecules for enhanced mucosal immunity

1999 • 32 citations

Characterization of Haemophilus influenzae Isolates from the Respiratory Tract of Patients with Primary Antibody Deficiencies: Evidence for Persistent Colonizations

1995 • 31 citations

Enhancement of immune response to intranasal influenza HA vaccine by microparticle resin

1998 • 28 citations

A combination of interleukin-2 and 60 nm cationic supramolecular biovectors for the treatment of established tumours by subcutaneous or intranasal administration

2001 • 21 citations

CD8⁺T Cells Have an Essential Role in Pulmonary Clearance of NontypeableHaemophilus influenzaefollowing Mucosal Immunization

2001 • 18 citations

The comparison of the effect of LTR72 and MF59 adjuvants on mouse humoral response to intranasal immunisation with human papillomavirus type 6b (HPV-6b) virus-like particles

2000 • 17 citations

Innate Defences and Resistance to Gram Negative Mucosal Infection

2005 • 16 citations