Interactions of β and γENaC with Nedd4 Can Be Facilitated by an ERK-mediated Phosphorylation

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2001 • 3,897 citations

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1997 • 1,154 citations

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome.

1996 • 828 citations

Epithelial sodium channel regulated by aldosterone-induced protein sgk

1999 • 728 citations

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na+ channel cell surface expression

2001 • 699 citations

Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination

1997 • 696 citations

Function of WW Domains as Phosphoserine- or Phosphothreonine-Binding Modules

1999 • 663 citations

Extracellular-signal-regulated kinase signalling in neurons

1999 • 554 citations

The Kidney: Physiology and Pathophysiology

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sgk Is an Aldosterone-induced Kinase in the Renal Collecting Duct

1999 • 452 citations

Serum and Glucocorticoid-regulated Kinase Modulates Nedd4-2-mediated Inhibition of the Epithelial Na+Channel

2002 • 451 citations

Identification of substrate recognition determinants for human ERK1 and ERK2 protein kinases.

1991 • 446 citations

Role of Ras and Mapks in TGFβ signaling

2000 • 430 citations

Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: A quantitative approach

1996 • 418 citations

Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome.

1996 • 397 citations

Identification of multiple epidermal growth factor-stimulated protein serine/threonine kinases from Swiss 3T3 cells.

1990 • 336 citations

Solution structure of a Nedd4 WW domain-ENaC peptide complex.

2001 • 221 citations

The C2 Domain of the Ubiquitin Protein Ligase Nedd4 Mediates Ca2+-dependent Plasma Membrane Localization

1997 • 199 citations

In vivo phosphorylation of the epithelial sodium channel

1998 • 168 citations

Characterization of early aldosterone-induced RNAs identified in A6 kidney epithelia

1997 • 133 citations

Phosphorylation-dependent targeting of cAMP response element binding protein to the ubiquitin/proteasome pathway in hypoxia

2000 • 132 citations

Phosphoinositide 3-kinase is required for aldosterone-regulated sodium reabsorption

1999 • 132 citations

Electrophysiological Characterization of the Rat Epithelial Na+ Channel (rENaC) Expressed in MDCK Cells

1998 • 126 citations

All Three WW Domains of Murine Nedd4 Are Involved in the Regulation of Epithelial Sodium Channels by Intracellular Na+

1999 • 123 citations

Aldosterone induces Ras methylation in A6 epithelia

2000 • 108 citations

Osmotic pressure regulates αβγ-rENaC expressed inXenopus oocytes

1998 • 93 citations

Raf‐1 is activated by the p38 mitogen‐activated protein kinase inhibitor, SB203580

1999 • 86 citations

Ras Pathway Activates Epithelial Na⁺Channel and Decreases Its Surface Expression inXenopusOocytes

1998 • 82 citations

Amiloride-sensitive Na channels

1998 • 82 citations

Human Nedd4 interacts with the human epithelial Na+ channel: WW3 but not WW1 binds to Na+-channel subunits

2000 • 54 citations

The Amiloride-sensitive Epithelial Sodium Channel α-Subunit Is Transcriptionally Down-regulated in Rat Parotid Cells by the Extracellular Signal-regulated Protein Kinase Pathway

1998 • 52 citations

Differential Activation of Mitogen-activated Protein Kinase and S6 Kinase Signaling Pathways by 12-O-Tetradecanoylphorbol-13-acetate (TPA) and Insulin

1995 • 49 citations

The Gene Expression of the Amiloride-sensitive Epithelial Sodium Channel α-Subunit Is Regulated by Antagonistic Effects between Glucocorticoid Hormone and Ras Pathways in Salivary Epithelial Cells

1999 • 36 citations

Human Nedd4 interacts with the human epithelial Na+ channel: WW3 but not WW1 binds to Na+-channel subunits

2000 • 34 citations

Characterization of Interactions between Nedd4 and β and γENaC Using Surface Plasmon Resonance

2001 • 28 citations