Regulation of tyrosine hydroxylase by stress‐activated protein kinases

Specificity and mechanism of action of some commonly used protein kinase inhibitors

2000 • 4,109 citations

Specificity and mechanism of action of some commonly used protein kinase inhibitors

2000 • 3,002 citations

Interaction of 14-3-3 with Signaling Proteins Is Mediated by the Recognition of Phosphoserine

1996 • 1,371 citations

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activationofCREB

1998 • 975 citations

[37] Protein phosphatase-1 and protein phosphatase-2A from rabbit skeletal muscle

1988 • 418 citations

PRAK, a novel protein kinase regulated by the p38 MAP kinase

1998 • 327 citations

Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

1999 • 326 citations

Pterin-Dependent Amino Acid Hydroxylases

1996 • 318 citations

Brain 14‐3‐3 protein is an activator protein that activates tryptophan 5‐monooxygenase and tyrosine 3‐monooxygenase in the presence of Ca²⁺,calmodulin‐dependent protein kinase II

1987 • 275 citations

Identification of four phosphorylation sites in the N-terminal region of tyrosine hydroxylase.

1986 • 243 citations

A new activator protein that activates tryptophan 5-monooxygenase and tyrosine 3-monooxygenase in the presence of Ca2+-, calmodulin-dependent protein kinase. Purification and characterization.

1981 • 234 citations

Serine 727 Phosphorylation and Activation of Cytosolic Phospholipase A2 by MNK1-related Protein Kinases

2000 • 228 citations

Phosphorylation of tyrosine hydroxylase in situ at serine 8, 19, 31, and 40.

1990 • 224 citations

A rapid and sensitive assay for tyrosine-3-monooxygenase based upon the release of 3H2O and adsorption of [3H]-tyrosine by charcoal

1986 • 203 citations

Phosphorylation and activation of human tyrosine hydroxylase in vitro by mitogen‐activated protein (MAP) kinase and MAP‐kinase‐activated kinases 1 and 2

1993 • 175 citations

[29] Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf

1995 • 163 citations

Tyrosine hydroxylase in rat brain dopaminergic nerve terminals. Multiple-site phosphorylation in vivo and in synaptosomes.

1991 • 155 citations

Phosphorylation of tyrosine hydroxylase by calmodulin-dependent multiprotein kinase.

1984 • 152 citations

Distinct forms of the protein kinase-dependent activator of tyrosine and tryptophan hydroxylases

1991 • 108 citations

Recombinant human tyrosine hydroxylase isozymes

1991 • 106 citations

MAPKAPK5, a Novel Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinase, Is a Substrate of the Extracellular-Regulated Kinase (ERK) and p38 Kinase

1998 • 105 citations

Depolarization‐stimulated catecholamine biosynthesis: involvement of protein kinases and tyrosine hydroxylase phosphorylation sites in situ

2001 • 101 citations

Stimulus-Coupled Interaction of Tyrosine Hydroxylase with 14-3-3 Proteins

1999 • 96 citations

Characterization of the sites phosphorylated on tyrosine hydroxylase by Ca²⁺ and phospholipid‐dependent protein kinase, calmodulin‐dependent multiprotein kinase and cyclic AMP‐dependent protein kinase

1985 • 95 citations

Regulation of recombinant human tyrosine hydroxylase isozymes by catecholamine binding and phosphorylation

1992 • 87 citations

Activation of extracellular signal‐regulated kinases 1 and 2 by depolarization stimulates tyrosine hydroxylase phosphorylation and dopamine synthesis in rat brain

2002 • 84 citations

Phosphorylation of Ser19 Alters the Conformation of Tyrosine Hydroxylase to Increase the Rate of Phosphorylation of Ser40

2001 • 81 citations

Stoichiometry of Tyrosine Hydroxylase Phosphorylation in the Nigrostriatal and Mesolimbic Systems In Vivo

2000 • 77 citations

Interaction of phosphorylated tyrosine hydroxylase with 14‐3‐3 proteins: evidence for a phosphoserine 40‐dependent association

2001 • 71 citations

Role of Serine‐19 Phosphorylation in Regulating Tyrosine Hydroxylase Studied with Site‐ and Phosphospecific Antibodies and Site‐Directed Mutagenesis

1998 • 66 citations

Regulation of Tyrosine Hydroxylase Activity and Phosphorylation at Ser¹⁹ and Ser⁴⁰ via Activation of Glutamate NMDA Receptors in Rat Striatum

2000 • 61 citations

Participation of a Stress‐Activated Protein Kinase Cascade in the Activation of Tyrosine Hydroxylase in Chromaffin Cells

1997 • 59 citations

Increased Site-Specific Phosphorylation of Tyrosine Hydroxylase Accompanies Stimulation of Enzymatic Activity Induced by Cessation of Dopamine Neuronal Activity

1999 • 48 citations

Site-directed mutagenesis of tyrosine hydroxylase. Role of serine 40 in catalysis.

1992 • 38 citations

Thermal Stability and CD Analysis of Rat Tyrosine Hydroxylase

1995 • 34 citations

Conformation and interaction of phenylalanine with the divalent cation at the active site of human recombinant tyrosine hydroxylase as determined by proton NMR

1993 • 30 citations

The binding of tyrosine hydroxylase to negatively charged lipid bilayers involves the N‐terminal region of the enzyme

2002 • 20 citations

Phosphorylation of Tyrosine Hydroxylase in Isolated Mice Adrenal Glands

2002 • 16 citations

Determination of Phosphorylation Levels of Tyrosine Hydroxylase by Electrospray Mass Spectrometry

2000 • 8 citations