Methods of Analysis for Chemicals that Promote/Disrupt Cellular Signaling

Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase

2000 • 1,411 citations

Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation

2000 • 662 citations

Estrogen-induced activation of mitogen-activated protein kinase requires mobilization of intracellular calcium

1999 • 336 citations

Enhancement of uphill transport by a double carrier membrane system

1988 • 320 citations

Cloning of the human oestrogen receptor cDNA

1986 • 299 citations

Fluorescent indicators for imaging protein phosphorylation in single living cells

2002 • 278 citations

Split Luciferase as an Optical Probe for Detecting Protein−Protein Interactions in Mammalian Cells Based on Protein Splicing

2001 • 250 citations

Ion-channel sensors

1987 • 188 citations

A Fluorescent Indicator for Detecting Protein−Protein Interactions in Vivo Based on Protein Splicing

2000 • 130 citations

Fluorescent Indicators for Cyclic GMP Based on Cyclic GMP-Dependent Protein Kinase Iα and Green Fluorescent Proteins

2000 • 125 citations

Electrochemical Detection of a One-Base Mismatch in an Oligonucleotide Using Ion-Channel Sensors with Self-Assembled PNA Monolayers

2000 • 88 citations

Imaging of Conformational Changes of Proteins with a New Environment-Sensitive Fluorescent Probe Designed for Site-Specific Labeling of Recombinant Proteins in Live Cells

2001 • 86 citations

Ion channel sensors for glutamic acid

1991 • 81 citations

Protein Splicing-Based Reconstitution of Split Green Fluorescent Protein for Monitoring Protein−Protein Interactions in Bacteria: Improved Sensitivity and Reduced Screening Time

2001 • 77 citations

Voltammetric Detection of the Polycation Protamine by the Use of Electrodes Modified with Self-Assembled Monolayers of Thioctic Acid

1999 • 73 citations

Ion-Channel-Mimetic Sensing of Hydrophilic Anions Based on Monolayers of a Hydrogen Bond-Forming Receptor

1999 • 66 citations

Chemical Sensing with Chemically Modified Electrodes that Mimic Gating at Biomembranes Incorporating Ion-Channel Receptors

1998 • 63 citations

17β-Estradiol regulation of protein kinase C activity in chondrocytes is sex-dependent and involves nongenomic mechanisms

1998 • 61 citations

An SPR-Based Screening Method for Agonist Selectivity for Insulin Signaling Pathways Based on the Binding of Phosphotyrosine to Its Specific Binding Protein

1999 • 57 citations

Sodium(1+)/D-glucose cotransporter based bilayer lipid membrane sensor for D-glucose

1993 • 57 citations

Detection of protein–protein interactions in vivo based on protein splicing

2001 • 54 citations

Design and Application of Ion-Channel Sensors Based on Biological and Artificial Receptors

2002 • 53 citations

How Can Ca²⁺Selectively Activate Recoverin in the Presence of Mg²⁺? Surface Plasmon Resonance and FT-IR Spectroscopic Studies

2000 • 49 citations

Estradiol rapidly inhibits soluble guanylyl cyclase expression in rat uterus

2001 • 49 citations

In Vitro Analysis of Xenoestrogens by Enzyme Linked Receptor Assays (ELRA)

1998 • 40 citations

Biosensor Development with a Glutamate Receptor Ion-Channel Reconstituted in a Lipid Bilayer

1990 • 35 citations

Metal ion selectivity for formation of the calmodulin–metal–target peptide ternary complex studied by surface plasmon resonance spectroscopy

1999 • 34 citations

A Fluorescent Indicator for Tyrosine Phosphorylation-Based Insulin Signaling Pathways

1999 • 34 citations

Electrochemical evaluation of chemical selectivity of glutamate receptor ion channel proteins with a multi-channel sensor

1997 • 32 citations

Uphill transport membrane electrodes

1986 • 26 citations

Assay and screening methods for bioactive substances based on cellular signaling pathways

2002 • 23 citations

Evaluation of agonist selectivity for the NMDA receptor ion channel in bilayer lipid membranes based on integrated single-channel currents

2000 • 23 citations

An Optical Method for Evaluating Ion Selectivity for Calcium Signaling Pathways in the Cell

1997 • 21 citations

An Assay Method for Evaluating Chemical Selectivity of Agonists for Insulin Signaling Pathways Based on Agonist-Induced Phosphorylation of a Target Peptide

1998 • 13 citations

AN EVALUATION OF SIGNAL AMPLIFICATION BY THE ION CHANNEL SEBSIR BASED ON A GLUTAMATE RECEPTOR ION CHANNEL PROTEIN

1991 • 13 citations

Screening method for antagonists that inhibit the binding of calmodulin to a target peptide using surface plasmon resonance

2001 • 13 citations

A method for evaluating chemical selectivity of agonists for glutamate receptor channels incorporated in liposomes based on an agonist-induced ion flux measured by ion-selective electrodes

1999 • 10 citations

Concentration of Dopamine by Proton-Driven Uphill Transport Using Lasalocid A as the Carrier

1996 • 8 citations

Enhancement of Analyte Concentration Based on a Feed/Receiving Volume Effect in Uphill Membrane Transport

1991 • 8 citations

A Screening Method for Antigen-Specific IgE Using Mast Cells Based on Intracellular Calcium Signaling

2000 • 5 citations

Methods of analysis.

2000 • 3 citations