Cell membrane hybrid bilayers containing the G-protein-coupled receptor CCR5

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1977 • 8,485 citations

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1996 • 4,184 citations

Identification of a major co-receptor for primary isolates of HIV-1

1996 • 3,649 citations

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

1996 • 3,189 citations

CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1

1996 • 2,735 citations

Adsorption of bifunctional organic disulfides on gold surfaces

1983 • 2,242 citations

Supported Membranes: Scientific and Practical Applications

1996 • 2,116 citations

Single bilayer liposomes prepared without sonication

1973 • 1,301 citations

G Protein-coupled Receptors

1998 • 1,292 citations

Uncovering Molecular Mechanisms Involved in Activation of G Protein-Coupled Receptors

2000 • 1,199 citations

CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5

1996 • 1,181 citations

A biosensor that uses ion-channel switches

1997 • 1,090 citations

High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment

1984 • 898 citations

Expression of a synthetic bovine rhodopsin gene in monkey kidney cells.

1987 • 444 citations

Monoclonal antibodies to rhodopsin: characterization, cross-reactivity, and application as structural probes

1983 • 392 citations

Antigen-Antibody Binding and Mass Transport by Convection and Diffusion to a Surface: A Two-Dimensional Computer Model of Binding and Dissociation Kinetics

1993 • 363 citations

SPR Studies of the Nonspecific Adsorption Kinetics of Human IgG and BSA on Gold Surfaces Modified by Self-Assembled Monolayers (SAMs)

1997 • 345 citations

Supported Hybrid Bilayer Membranes as Rugged Cell Membrane Mimics

1999 • 334 citations

Heptahelical Receptor Signaling: Beyond the G Protein Paradigm

1999 • 323 citations

Surface Plasmon Resonance Detection and Multispot Sensing for Direct Monitoring of Interactions Involving Low-Molecular-Weight Analytes and for Determination of Low Affinities

1995 • 278 citations

Micropatterned immobilization of a G protein–coupled receptor and direct detection of G protein activation

1999 • 276 citations

A single amino acid substitution in rhodopsin (lysine 248—-leucine) prevents activation of transducin.

1988 • 260 citations

Interpretation of Deviations from Pseudo-First-Order Kinetic Behavior in the Characterization of Ligand Binding by Biosensor Technology

1996 • 242 citations

Differential immunogold-dextran labeling of bovine and frog rod and cone cells using monoclonal antibodies against bovine rhodopsin

1986 • 224 citations

Incorporation of Rhodopsin in Laterally Structured Supported Membranes: Observation of Transducin Activation with Spatially and Time-Resolved Surface Plasmon Resonance

1998 • 173 citations

Using Receptor Conformational Change To Detect Low Molecular Weight Analytes by Surface Plasmon Resonance

2001 • 138 citations

Charge transport by ion translocating membrane proteins on solid supported membranes

1993 • 137 citations

Monocyte Chemotactic Protein-2 Activates CCR5 and Blocks CD4/CCR5-mediated HIV-1 Entry/Replication

1998 • 137 citations

Enhanced Expression, Native Purification, and Characterization of CCR5, a Principal HIV-1 Coreceptor

1999 • 134 citations

Identification and Optimization of Regeneration Conditions for Affinity-Based Biosensor Assays. A Multivariate Cocktail Approach

1999 • 121 citations

A biosensor assay for studying ligand-membrane receptor interactions: Binding of antibodies and HIV-1 Env to chemokine receptors

2000 • 109 citations

Self assembly driven by hydrophobic interactions at alkanethiol monolayers: mechanism of formation of hybrid bilayer membranes

1998 • 94 citations

Biotechnological applications of surface plasmon resonance

1997 • 94 citations

Light-stable rhodopsin. I. A rhodopsin analog reconstituted with a nonisomerizable 11-cis retinal derivative.

1992 • 91 citations

CCR5 Has an Expanded Ligand-Binding Repertoire and Is the Primary Receptor Used by MCP-2 on Activated T Cells

1998 • 87 citations

A non-covalent method of attaching antibodies to liposomes

1987 • 72 citations

Coupling of proton translocation through ATPase incorporated into supported lipid bilayers to an electrochemical process

1997 • 71 citations

Synthesis and Characterization of Self-Assembled Monolayers of Alkylated 1-Thiahexa(ethylene oxide) Compounds on Gold

1998 • 56 citations

Structural determinants of CCR5 recognition and HIV-1 blockade in RANTES.

2001 • 49 citations

Characterization of biomimetic surfaces formed from cell membranes

1997 • 44 citations

Sulphur-bearing lipids for the covalent attachment of supported lipid bilayers to gold surfaces: a detailed characterisation and analysis

1996 • 29 citations

Detection of porphyrin using a short peptide immobilized on a surface plasmon resonance sensor chip

2001 • 19 citations