Unravelling Carbohydrate Interactions with Biosensors Using Surface Plasmon Resonance (SPR) Detection

Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors

1998 • 3,843 citations

Immobilization of proteins to a carboxymethyldextran-modified gold surface for biospecific interaction analysis in surface plasmon resonance sensors

1991 • 1,263 citations

Advances in surface plasmon resonance biosensor analysis

2000 • 627 citations

Experimental design for kinetic analysis of protein-protein interactions with surface plasmon resonance biosensors

1997 • 556 citations

Surface plasmon resonance analysis of dynamic biological interactions with biomaterials

2000 • 501 citations

Specific interaction between Lex and Lex Determinants

1989 • 450 citations

Binding Strength Between Cell Adhesion Proteoglycans Measured by Atomic Force Microscopy

1995 • 419 citations

Functional Role of Glycosphingolipids in Cell Recognition and Signaling

1995 • 393 citations

Effect of N-linked glycosylation on glycopeptide and glycoprotein structure

1999 • 383 citations

Cholera Toxin Binding Affinity and Specificity for Gangliosides Determined by Surface Plasmon Resonance

1996 • 335 citations

Stromal Cell-derived Factor-1α Associates with Heparan Sulfates through the First β-Strand of the Chemokine

1999 • 322 citations

Comparison of the carbohydrate-binding specificities of cholera toxin and Escherichia coli heat-labile enterotoxins LTh-I, LT-IIa, and LT-IIb

1988 • 269 citations

Probing Low Affinity and Multivalent Interactions with Surface Plasmon Resonance: Ligands for Concanavalin A

1998 • 268 citations

Selective Inhibition of Aβ Fibril Formation

1996 • 229 citations

Detection of antigen—antibody interactions by surface plasmon resonance. Application to Epitope Mapping

1990 • 225 citations

Binding of Multivalent Carbohydrates to Concanavalin A andDioclea grandiflora Lectin

2000 • 211 citations

Affinity and Kinetic Analysis of P-selectin Binding to P-selectin Glycoprotein Ligand-1

1998 • 209 citations

Quantitative Analysis of Bacterial Toxin Affinity and Specificity for Glycolipid Receptors by Surface Plasmon Resonance

1997 • 206 citations

Nonstatistical binding of a protein to clustered carbohydrates

1999 • 201 citations

Nature of the interaction of heparin with acidic fibroblast growth factor

1993 • 192 citations

Thermodynamics of intersubunit interactions in cholera toxin upon binding to the oligosaccharide portion of its cell surface receptor, ganglioside GM1

1989 • 177 citations

Electrospray ionization mass spectrometry for the study of non-covalent complexes: an emerging technology

1998 • 162 citations

Analysis of affinity and structural selectivity in the binding of proteins to glycosaminoglycans: development of a sensitive electrophoretic approach.

1991 • 153 citations

Sensitivity enhancement of optical immunosensors by the use of a surface plasmon resonance fluoroimmunoassay

1991 • 148 citations

Analysis by Surface Plasmon Resonance of the Influence of Valence on the Ligand Binding Affinity and Kinetics of an Anti-carbohydrate Antibody

1996 • 135 citations

Polystyrene‐Adsorbed Gangliosides for Investigation of the Structure of the Tetanus‐Toxin Receptor

1980 • 132 citations

Interaction of Lipoprotein Lipase with Heparin Fragments and with Heparan Sulfate: Stoichiometry, Stabilization, and Kinetics

1996 • 128 citations

Surface plasmon resonance analysis at a supported lipid monolayer

1998 • 122 citations

Further studies on cell adhesion based on Lex-Lex interaction, with new approaches: embryoglycan aggregation of F9 teratocarcinoma cells, and adhesion of various tumour cells based on Lex expression

1994 • 122 citations

Lectin-Based Affinity Capture for MALDI-MS Analysis of Bacteria

1999 • 111 citations

Kinetic measurement of the interaction between an oligosaccharide and lectins by a biosensor based on surface plasmon resonance

1994 • 111 citations

Specificity of C-Glycoside Complexation by Mannose/Glucose Specific Lectins

1996 • 110 citations

Characterization of the Carbohydrate Binding Specificity and Kinetic Parameters of Lectins by Using Surface Plasmon Resonance

1999 • 109 citations

Delineation and comparison of ganglioside-binding epitopes for the toxins of Vibrio cholerae, Escherichia coli, and Clostridium tetani: evidence for overlapping epitopes.

1994 • 109 citations

Free and protein-bound carbohydrate structures

1999 • 107 citations

Selection of antibody single-chain variable fragments with improved carbohydrate binding by phage display

1994 • 92 citations

Identification of Extracellular Matrix Ligands for the Heparan Sulfate Proteoglycan Agrin

1999 • 92 citations

Chemical Structure, Molecular Conformation, and Bioactivity of Endotoxins

1999 • 88 citations

Interaction of Human Macrophage C-type Lectin withO-Linked N-Acetylgalactosamine Residues on Mucin Glycopeptides

1999 • 84 citations

Characterization of a novel pyruvylated carbohydrate unit implicated in the cell aggregation of the marine sponge Microciona prolifera

1993 • 82 citations

Fuc-GM1 ganglioside mimics the receptor function of GM1 for cholera toxin

1992 • 82 citations

Characterization of protein-glycolipid recognition at the membrane bilayer

1999 • 80 citations

Characterization of a Novel Sulfated Carbohydrate Unit Implicated in the Carbohydrate-Carbohydrate-mediated Cell Aggregation of the Marine Sponge Microciona prolifera

1995 • 77 citations

Interaction of Lipoproteins with Heparan Sulfate Proteoglycans and with Lipoprotein Lipase. Studies by Surface Plasmon Resonance Technique

1997 • 77 citations

[15] Determination of rate and equilibrium binding constants for macromolecular interactions by surface plasmon resonance

1994 • 75 citations

Elucidation of the mechanism enhancing the avidity of lectin with oligosaccharides on the solid phase surface

1997 • 74 citations

Carbohydrate-carbohydrate interactions in adhesion

1996 • 73 citations

Comparison of the glycolipid-binding specificities of cholera toxin and porcineEscherichia coli heat-labile enterotoxin: identification of a receptor-active non-ganglioside glycolipid for the heat-labile toxin in infant rabbit small intestine

1994 • 69 citations

Interaction of Immobilized Recombinant Mouse C-Type Macrophage Lectin with Glycopeptides and Oligosaccharides

1994 • 69 citations

Interaction between collagens and glycosaminoglycans investigated using a surface plasmon resonance biosensor

1999 • 69 citations

Antigen Binding Properties of Purified Immunoglobulin A and Reconstituted Secretory Immunoglobulin A Antibodies

1996 • 68 citations

Effects of Solute Multivalence on the Evaluation of Binding Constants by Biosensor Technology: Studies with Concanavalin A and Interleukin-6 as Partitioning Proteins

1995 • 64 citations

Conformational Epitope of the Type III Group B Streptococcus Capsular Polysaccharide

1999 • 62 citations

Carbohydrate–Carbohydrate Recognition between Lewis ^X Glycoconjugates

1999 • 56 citations

Alternative Splicing Determines the Binding of Platelet-Derived Growth Factor (PDGF-AA) to Glycosaminoglycans

1996 • 55 citations

Carbohydrate-Carbohydrate Recognition between LewisX Glycoconjugates

1999 • 55 citations

Interaction of heparin with annexin V

1999 • 53 citations

Fatty acid trafficking in the adipocyte

1999 • 50 citations

Continuous weak-affinity immunosensing

2000 • 49 citations

Kinetic measurements of binding of galectin 3 to a laminin substratum.

1999 • 48 citations

Studies of interactions with weak affinities and low-molecular-weight compounds using surface plasmon resonance technology

1998 • 48 citations

NMR study of a LewisX pentasaccharide derivative: solution structure and interaction with cations

1999 • 45 citations

Detection and characterization of weak affinity antibody antigen recognition with biomolecular interaction analysis

1997 • 45 citations

Calreticulin Binding Affinity for Glycosylated Laminin

1996 • 43 citations

The murine lymphocyte receptor for IgE. II. Characterization of the multivalent nature of the B lymphocyte receptor for IgE.

1984 • 38 citations

The Role of Homophilic Binding in Anti-tumor Antibody R24 Recognition of Molecular Surfaces

1999 • 37 citations

Characterization of Glycoprotein Oligosaccharides Using Surface Plasmon Resonance

1994 • 37 citations

Glycation of apolipoprotein E impairs its binding to heparin: identification of the major glycation site

1999 • 37 citations

Molecular modelling of theDolichos biflorus seed lectin and its specific interactions with carbohydrates: ?-D-N-acetyl-galactosamine, Forssman disaccharide and blood group A trisaccharide

1994 • 37 citations

Homophilic binding of mouse monoclonal antibodies against GD3 ganglioside.

1990 • 36 citations

Lectins: From obscurity into the limelight

1998 • 36 citations

Characterization of Heparin Binding of Human Extracellular Superoxide Dismutase

1999 • 34 citations

The effect of the chain length of heparin on its interaction with lipoprotein lipase

1983 • 34 citations

Interaction of the Sarcin/Ricin Domain of 23 S Ribosomal RNA with Proteins L3 and L6

1999 • 31 citations

Interaction of soluble and surface‐bound heparin binding growth‐associated molecule with heparin

1999 • 28 citations

Low-Mr heparin is as potent as conventional heparin in releasing lipoprotein lipase, but is less effective in preventing hepatic clearance of the enzyme

1991 • 27 citations

A role for sulfated polysaccharide recognition in sponge cell aggregation

1987 • 26 citations

Kinetics of apolipoprotein E isoforms‐binding to the major glycosaminoglycans of the extracellular matrix

1999 • 26 citations

Analysis of Interaction between Lectin and Carbohydrate by Surface Plasmon Resonance

1999 • 25 citations

Surface Plasmon Resonance Measurement of the Binding of Low-Density Lipoprotein at a Heparin Surface

1999 • 24 citations

Kinetics of the interaction between the human factor VIIIa subunits: effects of pH, ionic strength, Ca2+ concentration, heparin, and activated protein C-catalyzed proteolysis

1995 • 23 citations

A kinetics approach to the characterization of an IgM specific for the glycolipid asialo-GM1

1998 • 22 citations

Co-operative binding of concanavalin A to A glycoprotein in lipid bilayers

1982 • 21 citations

Dynamics of carbohydrate residues of α1-acid glycoprotein (orosomucoid) followed by red-edge excitation spectra and emission anisotropy studies of Calcofluor White

1999 • 20 citations

Synthesis and conjugation of a sulfated disaccharide involved in the aggregation process of the marine sponge Microciona prolifera

2000 • 15 citations

Analysis of human serum antibody–carbohydrate interaction using biosensor based on surface plasmon resonance

1999 • 14 citations

Kinetic Analysis of the Binding of Ulex europeas Agglutinin 1 (UEA 1) to H-Antigenic Fucolipid

2000 • 12 citations

[17] Practical aspects of kinetic analysis

1992 • 6 citations

Probing Carbohydrate-Protein Interactions by High-Resolution NMR Spectroscopy

1998 • 4 citations

Atomic Force Microscopy Measurements of Intermolecular Binding Strength

2003 • 3 citations