Tumor targeting properties of monoclonal antibodies with different affinity for target antigen CD44V6 in nude mice bearing head‐and‐neck cancer xenografts

A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells

1991 • 1,685 citations

CD44 and Its Interaction with Extracellular Matrix

1993 • 1,082 citations

High affinity restricts the localization and tumor penetration of single-chain fv antibody molecules.

2001 • 599 citations

CD44 variant exon epitopes in primary breast cancer and length of survival

1995 • 363 citations

A modeling analysis of monoclonal antibody percolation through tumors: a binding-site barrier.

1990 • 343 citations

Prevention of tumor metastasis formation by anti-variant CD44.

1993 • 339 citations

CD44H regulates tumor cell migration on hyaluronate-coated substrate.

1992 • 334 citations

Colorectal cancer prognosis and expression of exon-v6-containing CD44 proteins

1994 • 319 citations

LFA-3, CD44, and CD45: Physiologic Triggers of Human Monocyte TNF and IL-1 Release

1990 • 300 citations

Human Immune Respone to Monoclonal Antibodies

1994 • 297 citations

Increased affinity leads to improved selective tumor delivery of single-chain Fv antibodies.

1998 • 234 citations

CD44 variant isoforms in non-Hodgkin's lymphoma: a new independent prognostic factor

1995 • 230 citations

Radioimmunolocalization of human carcinoma xenografts with B72.3 second generation monoclonal antibodies.

1988 • 140 citations

Molecular Cloning and Expression of Human and Rat Tumor Necrosis Factor Receptor Chain (p60) and Its Soluble Derivative, Tumor Necrosis Factor-Binding Protein

1990 • 135 citations

Therapeutic advantage of high-affinity anticarcinoma radioimmunoconjugates.

1992 • 127 citations

The Core Protein of Epican, a Heparan Sulfate Proteoglycan on Keratinocytes, Is an Alternative Form of CD44

1992 • 78 citations

Characterization of a high-affinity monoclonal antibody specific for CD44v6 as candidate for immunotherapy of squamous cell carcinomas

1996 • 77 citations

Safety and biodistribution of 99mTechnetium-labeled anti-CD44v6 monoclonal antibody BIWA 1 in head and neck cancer patients.

2000 • 73 citations

Monoclonal antibodies labeled with rhenium-186 using the MAG3 chelate: relationship between the number of chelated groups and biodistribution characteristics.

1996 • 70 citations

Iodination of monoclonal antibodies for diagnosis and radiotherapy using a convenient one vial method.

1986 • 58 citations

Radioimmunoscintigraphy and biodistribution of technetium-99m-labeled monoclonal antibody U36 in patients with head and neck cancer.

1995 • 52 citations

The Core Protein of Epican, a Heparan Sulfate Proteoglycan on Keratinocytes, Is an Alternative Form of CD44

1992 • 52 citations

Comparative dual label study of first and second generation antitumor-associated glycoprotein-72 monoclonal antibodies in colorectal cancer patients.

1993 • 50 citations

Comparisons between two monoclonal antibodies that bind to the same antigen but have differing affinities: uptake kinetics and 125I-antibody therapy efficacy in multicell spheroids.

1992 • 45 citations

Monoclonal antibody U36, a suitable candidate for clinical immunotherapy of squamous-cell carcinoma, recognizes a CD44 isoform

1996 • 42 citations

Comparison of the monoclonal antibodies 17-1A and 323/A3: the influence of the affinity on tumour uptake and efficacy of radioimmunotherapy in human ovarian cancer xenografts

1996 • 32 citations

Evaluation of soluble CD44v6 as a potential serum marker for head and neck squamous cell carcinoma.

1999 • 30 citations

Tumor Retention of ¹⁸⁶Re-MAG3, ¹¹¹In-DTPA and ¹²⁵I Labeled Monoclonal Antibody G250 in Nude Mice with Renal Cell Carcinoma Xenografts

1998 • 29 citations

Immunotherapy with low and high affinity monoclonal antibodies 17-1A and 323/A3 in a nude mouse xenograft carcinoma model.

1995 • 28 citations

Rapid blood clearance of immunoglobulin G2a and immunoglobulin G2b in nude mice.

1991 • 28 citations

Comparison of the biodistribution and the efficacy of monoclonal antibody labeled with either 131I or 186Re in human ovarian cancer xenografts

1997 • 23 citations

CD44 Isoforms, Including the CD44 V3 Variant, Are Expressed on Endothelium, Suggesting a Role for CD44 in the Immobilization of Growth Factors and the Regulation of the Local Immune Response

1998 • 23 citations

Rapid elimination of mouse/human chimeric monoclonal antibodies in nude mice

1997 • 15 citations