A Branched Peptide Mimotope of the Nicotinic Receptor Binding Site Is a Potent Synthetic Antidote against the Snake Neurotoxin α-Bungarotoxin

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

2001 • 1,736 citations

Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system.

1988 • 1,241 citations

A glia-derived acetylcholine-binding protein that modulates synaptic transmission

2001 • 564 citations

Synthetic multivalent ligands in the exploration of cell-surface interactions

2000 • 518 citations

Nicotinic receptors in the brain: correlating physiology with function

1999 • 450 citations

Nicotinic acetylcholine receptors in health and disease

1997 • 446 citations

Human neuronal nicotinic receptors

1997 • 418 citations

Brain nicotinic receptors: structure and regulation, role in learning and reinforcement

1998 • 314 citations

A Trivalent System from Vancomycin· <scp>d</scp> -Ala- <scp>d</scp> -Ala with Higher Affinity Than Avidin·Biotin

1998 • 313 citations

Multivalent Protein−Carbohydrate Interactions. A New Paradigm for Supermolecular Assembly and Signal Transduction

2001 • 287 citations

Spanning binding sites on allosteric proteins with polymer-linked ligand dimers

1998 • 277 citations

Snake venom α‐neurotoxins and other ‘three‐finger’ proteins

1999 • 272 citations

Designing a polyvalent inhibitor of anthrax toxin

2001 • 272 citations

Anatomy of the antigenic structure of a large memberane autoantigen, the muscle‐type nicotinic acetylcholine receptor

1998 • 194 citations

Recent advances in multiple antigen peptides

1996 • 150 citations

Current view on the structure-function relationship of postsynaptic neurotoxins from snake venoms

1987 • 147 citations

Topology of ligand binding sites on the nicotinic acetylcholine receptor

1997 • 142 citations

Analysis of ligand binding to the synthetic dodecapeptide 185-196 of the acetylcholine receptor alpha subunit.

1986 • 130 citations

The Binding Site of Acetylcholine Receptor as Visualized in the X-Ray Structure of a Complex between α-Bungarotoxin and a Mimotope Peptide

2001 • 129 citations

Ligand recognition by influenza virus. The binding of bivalent sialosides.

1991 • 112 citations

A β-hairpin structure in a 13-mer peptide that binds α-bungarotoxin with high affinity and neutralizes its toxicity

2001 • 64 citations

The α-bungarotoxin binding site on the nicotinic acetylcholine receptor: Analysis using a phage–epitope library

1997 • 56 citations

Design and synthesis of peptides that bind α-bungarotoxin with high affinity

2001 • 49 citations

Mimotopes of the Nicotinic Receptor Binding Site Selected by a Combinatorial Peptide Library

2001 • 39 citations

Peptide-protein interactions studied by surface plasmon and nuclear magnetic resonances

2001 • 27 citations

Differential Binding of Nicotine and .alpha.-Bungarotoxin to Residues 173-204 of the Nicotinic Acetylcholine Receptor .alpha.1 Subunit

1995 • 26 citations

NMR Structure of α-Bungarotoxin Free and Bound to a Mimotope of the Nicotinic Acetylcholine Receptor

2002 • 26 citations

Identification of sequence segments forming the alpha-bungarotoxin binding sites on two nicotinic acetylcholine receptor alpha subunits from the avian brain

1991 • 25 citations

An .alpha.-Bungarotoxin-Binding Sequence on the Torpedo Nicotinic Acetylcholine Receptor .alpha.-Subunit: Conservative Amino Acid Substitutions Reveal Side-Chain Specific Interactions

1994 • 23 citations

A cyclic peptide with high affinity to α-bungarotoxin protects mice from the lethal effect of the toxin

2001 • 5 citations