Morphogen Gradients: From Generation to Interpretation

The chemical basis of morphogenesis

1952 • 11,233 citations

A theory of biological pattern formation

1972 • 3,055 citations

Positional information and the spatial pattern of cellular differentiation

1969 • 2,957 citations

Directed Differentiation of Embryonic Stem Cells into Motor Neurons

2002 • 1,723 citations

Reaction-Diffusion Model as a Framework for Understanding Biological Pattern Formation

2010 • 1,465 citations

The segment polarity network is a robust developmental module

2000 • 1,177 citations

The Biochemical Basis of an All-or-None Cell Fate Switch in Xenopus Oocytes

1998 • 1,040 citations

The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner

1988 • 1,022 citations

A gradient of bicoid protein in Drosophila embryos

1988 • 1,015 citations

LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling:Arrows point the way

2004 • 990 citations

Evidence for an Expansion-Based Temporal Shh Gradient in Specifying Vertebrate Digit Identities

2004 • 970 citations

Identification and spatial distribution of retinoids in the developing chick limb bud

1987 • 964 citations

Direct and Long-Range Action of a DPP Morphogen Gradient

1996 • 896 citations

Diffusion in Embryogenesis

1970 • 895 citations

Dual Roles for Patched in Sequestering and Transducing Hedgehog

1996 • 889 citations

über Induktion von Embryonalanlagen durch Implantation artfremder Organisatoren

1924 • 817 citations

Direct and Long-Range Action of a Wingless Morphogen Gradient

1996 • 736 citations

The role of localization of bicoid RNA in organizing the anterior pattern of the Drosophila embryo.

1988 • 736 citations

Positional Information in Chick Limb Morphogenesis

1973 • 718 citations

Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network

2008 • 714 citations

Probing the Limits to Positional Information

2007 • 698 citations

Lipoprotein particles are required for Hedgehog and Wingless signalling

2005 • 678 citations

The gradient morphogen bicoid is a concentration-dependent transcriptional activator

1989 • 655 citations

A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo

1989 • 652 citations

Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing

1996 • 629 citations

Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs

1994 • 624 citations

Gradient Formation of the TGF-β Homolog Dpp

2000 • 606 citations

Cytonemes

1999 • 602 citations

Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism

2007 • 602 citations

Positional signalling and specification of digits in chick limb morphogenesis

1975 • 588 citations

WNT and DKK Determine Hair Follicle Spacing Through a Reaction-Diffusion Mechanism

2006 • 586 citations

Dynamic control of positional information in the early Drosophila embryo

2004 • 577 citations

Assigning numbers to the arrows: Parameterizing a gene regulation network by using accurate expression kinetics

2002 • 522 citations

Nodal signaling: developmental roles and regulation

2007 • 513 citations

Stability and Nuclear Dynamics of the Bicoid Morphogen Gradient

2007 • 510 citations

Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate

1990 • 508 citations

A morphogen gradient of Wnt/β-catenin signalling regulates anteroposterior neural patterning inXenopus

2001 • 504 citations

A molecular gradient in early Drosophila embryos and its role in specifying the body pattern

1986 • 504 citations

Target Protectors Reveal Dampening and Balancing of Nodal Agonist and Antagonist by miR-430

2007 • 501 citations

Dynamic Changes in the Response of Cells to Positive Hedgehog Signaling during Mouse Limb Patterning

2004 • 498 citations

Establishment of developmental precision and proportions in the early Drosophila embryo

2002 • 496 citations

Predicting expression patterns from regulatory sequence in Drosophila segmentation

2008 • 495 citations

Responses of embryonic xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm

1992 • 486 citations

decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo

1992 • 480 citations

Eukaryotic Chemotaxis: A Network of Signaling Pathways Controls Motility, Directional Sensing, and Polarity

2010 • 479 citations

The graded distribution of the dorsal morphogen is initiated by selective nuclear transport in Drosophila

1989 • 472 citations

The interpretation of morphogen gradients

2006 • 471 citations

Shadow Enhancers as a Source of Evolutionary Novelty

2008 • 467 citations

Robustness of the BMP morphogen gradient in Drosophila embryonic patterning

2002 • 463 citations

Comparative Aspects of Animal Regeneration

2008 • 462 citations

Dpp Gradient Formation in the Drosophila Wing Imaginal Disc

2000 • 453 citations

Wingless gradient formation in the Drosophila wing

2000 • 437 citations

Determination of spatial domains of zygotic gene expression in the Drosophila embryo by the affinity of binding sites for the bicoid morphogen

1989 • 432 citations

Relocalization of the dorsal protein from the cytoplasm to the nucleus correlates with its function

1989 • 431 citations

fgf8 mRNA decay establishes a gradient that couples axial elongation to patterning in the vertebrate embryo

2004 • 420 citations

Long-range action of Wingless organizes the dorsal-ventral axis of the Drosophila wing

1997 • 416 citations

Do Morphogen Gradients Arise by Diffusion?

2002 • 403 citations

Kinetics of Morphogen Gradient Formation

2007 • 398 citations

The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila

1999 • 393 citations

The Decapentaplegic morphogen gradient: from pattern formation to growth regulation

2007 • 377 citations

Regulation of Organogenesis by the Caenorhabditis elegans FoxA Protein PHA-4

2002 • 374 citations

Ordering Genes in a Flagella Pathway by Analysis of Expression Kinetics from Living Bacteria

2001 • 373 citations

Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless

2001 • 370 citations

Hedgehog Movement Is Regulated through tout velu–Dependent Synthesis of a Heparan Sulfate Proteoglycan

1999 • 367 citations

Fgf8 morphogen gradient forms by a source-sink mechanism with freely diffusing molecules

2009 • 367 citations

A Hedgehog-Insensitive Form of Patched Provides Evidence for Direct Long-Range Morphogen Activity of Sonic Hedgehog in the Neural Tube

2001 • 364 citations

Chromatin signature of embryonic pluripotency is established during genome activation

2010 • 364 citations

Dynamics of Dpp Signaling and Proliferation Control

2011 • 355 citations

Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1

1997 • 354 citations

Production of a DPP Activity Gradient in the Early Drosophila Embryo through the Opposing Actions of the SOG and TLD Proteins

1997 • 350 citations

Germ-Layer Specification and Control of Cell Growth by Ectodermin, a Smad4 Ubiquitin Ligase

2005 • 338 citations

Shaping Morphogen Gradients by Proteoglycans

2009 • 338 citations

Wingless Repression of Drosophila frizzled 2 Expression Shapes the Wingless Morphogen Gradient in the Wing

1998 • 331 citations

Morpheus Unbound: Reimagining the Morphogen Gradient

2007 • 329 citations

The zebrafish Nodal signal Squint functions as a morphogen

2001 • 328 citations

Activin signalling and response to a morphogen gradient

1994 • 328 citations

The dorsal gradient morphogen regulates stripes of rhomboid expression in the presumptive neuroectoderm of the Drosophila embryo.

1992 • 324 citations

Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I

2004 • 323 citations

Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen

1993 • 322 citations

The spätzle gene encodes a component of the extracellular signaling pathway establishing the dorsal-ventral pattern of the Drosophila embryo

1994 • 321 citations

Relationship between dose, distance and time in Sonic Hedgehog-mediated regulation of anteroposterior polarity in the chick limb

1997 • 314 citations

Diffusion and scaling during early embryonic pattern formation

2005 • 311 citations

dorsal-twist interactions establish snail expression in the presumptive mesoderm of the Drosophila embryo.

1992 • 309 citations

Drosophila Dpp Morphogen Movement Is Independent of Dynamin-Mediated Endocytosis but Regulated by the Glypican Members of Heparan Sulfate Proteoglycans

2004 • 297 citations

Evidence that Fold-Change, and Not Absolute Level, of β-Catenin Dictates Wnt Signaling

2009 • 295 citations

Canalization of Gene Expression in the Drosophila Blastoderm by Gap Gene Cross Regulation

2009 • 293 citations

Self-Enhanced Ligand Degradation Underlies Robustness of Morphogen Gradients

2003 • 292 citations

Multiple steps in the localization of bicoid RNA to the anterior pole of the Drosophila oocyte

1989 • 291 citations

Facilitated Transport of a Dpp/Scw Heterodimer by Sog/Tsg Leads to Robust Patterning of the Drosophila Blastoderm Embryo

2005 • 291 citations

Morphogen Gradient Formation

2009 • 289 citations

The Whereabouts of a Morphogen: Direct Evidence for Short- and Graded Long-Range Activity of Hedgehog Signaling Peptides

2001 • 288 citations

Expression of the caudal gene in the germ line of Drosophila: Formation of an RNA and protein gradient during early embryogenesis

1987 • 282 citations

ThreeDrosophilaEXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans

2003 • 274 citations

Dynamic Filopodia Transmit Intermittent Delta-Notch Signaling to Drive Pattern Refinement during Lateral Inhibition

2010 • 270 citations

A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube

2005 • 270 citations

Nodal signaling patterns the organizer

2000 • 261 citations

Hedgehog regulates smoothened activity by inducing a conformational switch

2007 • 258 citations

Chromatin decouples promoter threshold from dynamic range

2008 • 257 citations

Synchronous and Stochastic Patterns of Gene Activation in the Drosophila Embryo

2009 • 252 citations

Regulation of ADMP and BMP2/4/7 at Opposite Embryonic Poles Generates a Self-Regulating Morphogenetic Field

2005 • 247 citations

Regeneration

1901 • 247 citations

Dorsoventral Axis Formation in the Drosophila Embryo—Shaping and Transducing a Morphogen Gradient

2005 • 245 citations

Nodal Morphogens

2009 • 245 citations

Secretion and movement of wingless protein in the epidermis of the Drosophila embryo

1991 • 244 citations

The Xenopus Dorsalizing Factor noggin Ventralizes Drosophila Embryos by Preventing DPP from Activating Its Receptor

1996 • 242 citations

Establishment of the Mesoderm-Neuroectoderm Boundary in the Drosophila Embryo

1991 • 241 citations

Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning

2008 • 239 citations

Isolation of caudal , a Drosophila homeo box-containing gene with maternal expression, whose transcripts form a concentration gradient at the pre-blastoderm stage

1985 • 238 citations

Specificity of Drosophila Cytonemes for Distinct Signaling Pathways

2011 • 237 citations

Complex Regulation of cyp26a1 Creates a Robust Retinoic Acid Gradient in the Zebrafish Embryo

2007 • 234 citations

Scaling of the BMP activation gradient in Xenopus embryos

2008 • 230 citations

Dally regulates Dpp morphogen gradient formation in theDrosophilawing

2003 • 223 citations

Establishing and Interpreting Graded Sonic Hedgehog Signaling during Vertebrate Neural Tube Patterning: The Role of Negative Feedback

2009 • 221 citations

Drosophilaglypicans Dally and Dally-like shape the extracellular Wingless morphogen gradient in the wing disc

2005 • 216 citations

Drosophila hedgehog acts as a morphogen in cellular patterning

1994 • 215 citations

The BMP Signaling Gradient Patterns Dorsoventral Tissues in a Temporally Progressive Manner along the Anteroposterior Axis

2008 • 214 citations

A self-organizing system of repressor gradients establishes segmental complexity in Drosophila

2003 • 213 citations

Regulated Endocytic Routing Modulates Wingless Signaling in Drosophila Embryos

2001 • 211 citations

Spatial bistability of Dpp–receptor interactions during Drosophila dorsal–ventral patterning

2005 • 207 citations

Dependence of Drosophila wing imaginal disc cytonemes on Decapentaplegic

2005 • 205 citations

The Interpretation of Position in a Morphogen Gradient as Revealed by Occupancy of Activin Receptors

1998 • 205 citations

Dpp receptor levels contribute to shaping the Dpp morphogen gradient in the Drosophila wing imaginal disc

1998 • 202 citations

Different Levels of the C. elegans growth factor LIN-3 promote distinct vulval precursor fates

1995 • 200 citations

Generation of Robust Left-Right Asymmetry in the Mouse Embryo Requires a Self-Enhancement and Lateral-Inhibition System

2006 • 200 citations

Pre-Steady-State Decoding of the Bicoid Morphogen Gradient

2007 • 200 citations

The extracellular regulation of bone morphogenetic protein signaling

2009 • 199 citations

Dynamic Assignment and Maintenance of Positional Identity in the Ventral Neural Tube by the Morphogen Sonic Hedgehog

2010 • 197 citations

Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1

2000 • 195 citations

Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube

2010 • 191 citations

Dally regulates Dpp morphogen gradient formation by stabilizing Dpp on the cell surface

2007 • 190 citations

Experimental studies on the development of the eye in amphibia. I. On the origin of the lens. Rana palustris

1904 • 190 citations

Delta-promoted filopodia mediate long-range lateral inhibition in Drosophila

2003 • 181 citations

Cooperative DNA-binding by Bicoid provides a mechanism for threshold-dependent gene activation in the Drosophila embryo

1998 • 180 citations

The Formation of the Bicoid Morphogen Gradient Requires Protein Movement from Anteriorly Localized mRNA

2011 • 178 citations

Geometric and viscous components of the tortuosity of the extracellular space in the brain

1998 • 178 citations

Gradients in the Insect Segment: The Orientation of Hairs in the Milkweed Bug Oncopeltus Fasciatus

1966 • 178 citations

The role of binding site cluster strength in Bicoid-dependent patterning in Drosophila

2005 • 177 citations

From Signals to Patterns: Space, Time, and Mathematics in Developmental Biology

2008 • 168 citations

Lipoprotein-Heparan Sulfate Interactions in the Hh Pathway

2007 • 166 citations

The BMP-Binding Protein Crossveinless 2 Is a Short-Range, Concentration-Dependent, Biphasic Modulator of BMP Signaling in Drosophila

2008 • 163 citations

Lefty Proteins Are Long-Range Inhibitors of Squint-Mediated Nodal Signaling

2002 • 162 citations

Modelling the Bicoid gradient

2010 • 157 citations

Cellular Trafficking of the Glypican Dally-like Is Required for Full-Strength Hedgehog Signaling and Wingless Transcytosis

2008 • 155 citations

Hox Control of Organ Size by Regulation of Morphogen Production and Mobility

2006 • 154 citations

A quantitative model of transcription factor–activated gene expression

2008 • 152 citations

Scaling of morphogen gradients by an expansion-repression integral feedback control

2010 • 151 citations

Direct and continuous assessment by cells of their position in a morphogen gradient

1995 • 150 citations

Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog inDrosophilaepithelia

2006 • 148 citations

Formation of thebicoidmorphogen gradient: an mRNA gradient dictates the protein gradient

2009 • 147 citations

Precision of the Dpp gradient

2008 • 143 citations

Nanoscale Organization of Hedgehog Is Essential for Long-Range Signaling

2008 • 142 citations

Hedgehog lipid modifications are required for Hedgehog stabilization in the extracellular matrix

2006 • 139 citations

Bicoid Determines Sharp and Precise Target Gene Expression in the Drosophila Embryo

2005 • 136 citations

Control of Dpp morphogen signalling by a secreted feedback regulator

2010 • 136 citations

Multiple roles for lipids in the Hedgehog signalling pathway

2008 • 134 citations

Directionality of Wingless protein transport influences epidermal patterning in the Drosophila embryo

1999 • 133 citations

Extended exposure to Sonic hedgehog is required for patterning the posterior digits of the vertebrate limb

2007 • 131 citations

In vivo diffusion of lactoferrin in brain extracellular space is regulated by interactions with heparan sulfate

2008 • 127 citations

Segmentation gene expression in the housefly Musca domestica

1991 • 127 citations

Time-dependent patterning of the mesoderm and endoderm by Nodal signals in zebrafish

2007 • 126 citations

The Drosophila morphogenetic protein Bicoid binds DNA cooperatively

1996 • 124 citations

Endocytosis Controls Spreading and Effective Signaling Range of Fgf8 Protein

2004 • 122 citations

Positional information and patterning revisited

2010 • 121 citations

The Bicoid Morphogen System

2010 • 120 citations

Scale of body pattern adjusts to available cell number in amphibian embryos

1981 • 117 citations

Sog/Chordin is required for ventral-to-dorsal Dpp/BMP transport and head formation in a short germ insect

2006 • 115 citations

Nodal Signaling Recruits the Histone Demethylase Jmjd3 to Counteract Polycomb-Mediated Repression at Target Genes

2010 • 114 citations

Bicoid cooperative DNA binding is critical for embryonic patterning in Drosophila

2005 • 113 citations

Graded Dorsal and Differential Gene Regulation in the Drosophila Embryo

2009 • 113 citations

High Mobility of Bicoid Captured by Fluorescence Correlation Spectroscopy: Implication for the Rapid Establishment of Its Gradient

2010 • 112 citations

Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface.

1995 • 109 citations

Reading the Hedgehog morphogen gradient by measuring the ratio of bound to unbound Patched protein

2004 • 109 citations

Physical properties of Tld, Sog, Tsg and Dpp protein interactions are predicted to help create a sharp boundary in Bmp signals during dorsoventral patterning of theDrosophilaembryo

2003 • 109 citations

The cell-surface proteins Dally-like and Ihog differentially regulate Hedgehog signaling strength and range during development

2010 • 108 citations

The Core Protein of Glypican Dally-Like Determines Its Biphasic Activity in Wingless Morphogen Signaling

2009 • 107 citations

Analyse des ooplasmatischen Reaktionssystems vonEuscelis plebejus Fall (Cicadina) durch Isolieren und Kombinieren von Keimteilen

1960 • 107 citations

The evolution of dorsal–ventral patterning mechanisms in insects

2011 • 106 citations

The Long-Range Activity of Hedgehog Is Regulated in the Apical Extracellular Space by the Glypican Dally and the Hydrolase Notum

2010 • 106 citations

Dpp gradient formation by dynamin-dependent endocytosis: receptor trafficking and the diffusion model

2004 • 104 citations

Robust Stability of the Embryonic Axial Pattern Requires a Secreted Scaffold for Chordin Degradation

2008 • 103 citations

Drosophila embryonic pattern repair: how embryos respond to bicoid dosage alteration

1997 • 102 citations

Probing Intrinsic Properties of a Robust Morphogen Gradient in Drosophila

2008 • 99 citations

Scale-invariance in reaction-diffusion models of spatial pattern formation.

1980 • 98 citations

Anterior-posterior positional information in the absence of a strong Bicoid gradient

2009 • 97 citations

The role of megalin (LRP-2/Gp330) during development

2006 • 96 citations

Models for the Generation and Interpretation of Gradients

2009 • 94 citations

Patched, the receptor of Hedgehog, is a lipoprotein receptor

2008 • 92 citations

The time to measure positional information: maternal Hunchback is required for the synchrony of the Bicoid transcriptional response at the onset of zygotic transcription

2010 • 91 citations

Organism-Scale Modeling of Early Drosophila Patterning via Bone Morphogenetic Proteins

2010 • 90 citations

A quantitative analysis of signal transduction from activin receptor to nucleus and its relevance to morphogen gradient interpretation

1999 • 90 citations

Positional information and pattern regulation in regeneration of hydra.

1971 • 87 citations

Eomesodermin Is a Localized Maternal Determinant Required for Endoderm Induction in Zebrafish

2005 • 86 citations

Canalization of segmentation and its evolution in Drosophila

2007 • 86 citations

Extracellular regulation of BMP signaling

2010 • 86 citations

The Measure of Success: Constraints, Objectives, and Tradeoffs in Morphogen-mediated Patterning

2009 • 86 citations

Visualisation and Quantification of Morphogen Gradient Formation in the Zebrafish

2009 • 85 citations

Sulfated glycosaminoglycans are necessary for Nodal signal transmission from the node to the left lateral plate in the mouse embryo

2007 • 85 citations

Robust Generation and Decoding of Morphogen Gradients

2009 • 84 citations

Shape and function of the Bicoid morphogen gradient in dipteran species with different sized embryos

2008 • 84 citations

Mechanism by which Cells estimate their Location within the Body

1966 • 83 citations

A homeodomain feedback circuit underlies step-function interpretation of a Shh morphogen gradient during ventral neural patterning

2010 • 83 citations

Morphogen Transport along Epithelia, an Integrated Trafficking Problem

2002 • 82 citations

Dynamic Interpretation of Hedgehog Signaling in the Drosophila Wing Disc

2009 • 81 citations

Embryonic pattern scaling achieved by oppositely directed morphogen gradients

2006 • 79 citations

Antagonistic action of Bicoid and the repressor Capicua determines the spatial limits of Drosophila head gene expression domains

2009 • 76 citations

Morphogen gradient interpretation by a regulated trafficking step during ligand–receptor transduction

2005 • 74 citations

Antagonistic Growth Regulation by Dpp and Fat Drives Uniform Cell Proliferation

2011 • 74 citations

Temporal dynamics of patterning by morphogen gradients

2009 • 73 citations

Fates-shifted is an F-box protein that targets Bicoid for degradation and regulates developmental fate determination in Drosophila embryos

2010 • 68 citations

Scaling of the Bicoid morphogen gradient by a volume-dependent production rate

2011 • 68 citations

Drosophila heparan sulfate 6-O endosulfatase regulates Wingless morphogen gradient formation

2010 • 65 citations

A changing morphogen gradient is interpreted by continuous transduction flow

2002 • 62 citations

TheUltrabithoraxHox gene ofDrosophilacontrols haltere size by regulating the Dpp pathway

2006 • 62 citations

Multiple modes of dorsal-bHLH transcriptional synergy in the Drosophila embryo.

1995 • 60 citations

Rapid differential transport of Nodal and Lefty on sulfated proteoglycan-rich extracellular matrix regulates left-right asymmetry inXenopus

2011 • 56 citations

Interpretation of the FGF8 morphogen gradient is regulated by endocytic trafficking

2011 • 55 citations

Interpretation of the Wingless Gradient Requires Signaling-Induced Self-Inhibition

2009 • 55 citations

The control of size in animals: insights from selector genes

2008 • 53 citations

Smad Affinity Can Direct Distinct Readouts of the Embryonic Extracellular Dpp Gradient in Drosophila

2004 • 50 citations

Hedgehog morphogen: from secretion to reception

2011 • 50 citations

Precision and scaling in morphogen gradient read‐out

2010 • 48 citations

The Decapentaplegic morphogen gradient: a precise definition

2008 • 48 citations

A translational block to HSPG synthesis permits BMP signaling in the earlyDrosophilaembryo

2008 • 46 citations

Gradients and the Specification of Planar Polarity in the Insect Cuticle

2009 • 44 citations

Form and Causality in Early Development

1939 • 44 citations

Form and Causality in Early Development

1940 • 43 citations

Feedback regulation ofDrosophilaBMP signaling by the novel extracellular protein Larval Translucida

2011 • 41 citations

Lipid-modified morphogens: functions of fats

2009 • 40 citations

Syndecan-1 regulates BMP signaling and dorso-ventral patterning of the ectoderm during early Xenopus development

2009 • 32 citations

When it pays to rush: interpreting morphogen gradients prior to steady-state

2009 • 31 citations

Robustness of positional specification by the Hedgehog morphogen gradient

2010 • 24 citations

11.4 Entwicklungsprobleme

2013 • 19 citations

Egg ligation alter the Bcd protein gradient and segmentation gene expression in embryos of Drosophila

1993 • 13 citations

Generation and interpretation of morphogen gradients : a subject collection from Cold Spring Harbor perspectives in biology

2010 • 8 citations

EGF receptor signaling — a quantitative view

2007 • 5 citations