A gradient of bicoid protein in Drosophila embryos

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Mutations affecting segment number and polarity in Drosophila

1980 • 4,280 citations

A theory of biological pattern formation

1972 • 3,055 citations

Positional information and the spatial pattern of cellular differentiation

1969 • 2,957 citations

Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis

1986 • 2,566 citations

The embryonic development of Drosophila melanogaster

1938 • 2,188 citations

Derivation of specific antibody‐producing tissue culture and tumor lines by cell fusion

1976 • 1,926 citations

Models of biological pattern formation

1982 • 1,851 citations

Production of monoclonal antibodies: Strategy and tactics

1980 • 1,594 citations

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster

1984 • 1,546 citations

Rapid and sensitive colorimetric method for visualizing biotin-labeled DNA probes hybridized to DNA or RNA immobilized on nitrocellulose: Bio-blots.

1983 • 1,075 citations

A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes

1984 • 1,066 citations

Studies of nuclear and cytoplasmic behaviour during the five mitotic cycles that precede gastrulation in Drosophila embryogenesis

1983 • 1,034 citations

The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner

1988 • 1,022 citations

Identification and spatial distribution of retinoids in the developing chick limb bud

1987 • 964 citations

Diffusion in Embryogenesis

1970 • 895 citations

A maternal mRNA localized to the vegetal hemisphere in xenopus eggs codes for a growth factor related to TGF-β

1987 • 747 citations

The role of localization of bicoid RNA in organizing the anterior pattern of the Drosophila embryo.

1988 • 736 citations

Fusion between immunoglobulin‐secreting and nonsecreting myeloma cell lines

1976 • 729 citations

Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins

1984 • 686 citations

Determination of Anteroposterior Polarity in Drosophila

1987 • 651 citations

Easy identification of cDNA clones.

1983 • 587 citations

A molecular gradient in early Drosophila embryos and its role in specifying the body pattern

1986 • 504 citations

Structure of the segmentation gene paired and the Drosophila PRD gene set as part of a gene network

1986 • 496 citations

Vitamin A and pattern formation in the regenerating limb

1982 • 463 citations

Abdominal segmentation, pole cell formation, and embryonic polarity require the localized activity of oskar, a maternal gene in drosophila

1986 • 463 citations

Specification of the Basic Body Pattern in Insect Embryogenesis

1976 • 436 citations

GCN4, a eukaryotic transcriptional activator protein, binds as a dimer to target DNA.

1987 • 395 citations

THE MECHANICS OF SEA URCHIN DEVELOPMENT, STUDIED BY OPERATIVE METHODS

1939 • 388 citations

The Drosophila developmental gene, engrailed, encodes a sequence-specific DNA binding activity

1985 • 387 citations

Organization of anterior pattern in the Drosophila embryo by the maternal gene bicoid

1986 • 386 citations

Regulation of the Drosophila segmentation gene hunchback by two maternal morphogenetic centres

1988 • 366 citations

The embryonic development of Drosophila melanogaster

1986 • 339 citations

Identification and immunochemical analysis of biologically active Drosophila P element transposase

1986 • 318 citations

Localization of the fushi tarazu protein during Drosophila embryogenesis

1985 • 290 citations

hunchback, a gene required for segmentation of an anterior and posterior region of the Drosophila embryo

1987 • 289 citations

Expression of the caudal gene in the germ line of Drosophila: Formation of an RNA and protein gradient during early embryogenesis

1987 • 282 citations

Thresholds in development

1977 • 247 citations

Isolation of caudal , a Drosophila homeo box-containing gene with maternal expression, whose transcripts form a concentration gradient at the pre-blastoderm stage

1985 • 238 citations

Diffusion of a small molecule in the cytoplasm of mammalian cells.

1984 • 228 citations

Analysis of Krüppel protein distribution during early Drosophila development reveals posttranscriptional regulation

1987 • 222 citations

Mobility of microinjected rhodamine actin within living chicken gizzard cells determined by fluorescence photobleaching recovery

1982 • 206 citations

Maternal Effect Mutations that Alter the Spatial Coordinates of the Embryo of Drosophila melanogaste

1979 • 193 citations

Isolation and amino acid sequence of a morphogenetic peptide from hydra

1981 • 180 citations

Gradients in the Insect Segment: The Orientation of Hairs in the Milkweed Bug Oncopeltus Fasciatus

1966 • 178 citations

Diffusion of injected macromolecules within the cytoplasm of living cells.

1981 • 174 citations

Hierarchical Inductions of Cell States: A Model for Segmentation in Drosophila

1986 • 157 citations

DETERMINANTS OF SPATIAL ORGANIZATION

1979 • 157 citations

A model of pattern formation in insect embryogenesis

1977 • 154 citations

In vitro activation of Drosophila eggs

1983 • 141 citations

Individuality in organisms

1915 • 110 citations

Analyse des ooplasmatischen Reaktionssystems vonEuscelis plebejus Fall (Cicadina) durch Isolieren und Kombinieren von Keimteilen

1960 • 107 citations

Maternal genes required for the anterior localization of bicoid activity in the embryo of Drosophila

1987 • 105 citations

Analyse des ooplasmatischen Reaktionssystems vonEuscelis plebejus Fall. (Cicadina) durch Isolieren und Kombinieren von Keimteilen

1959 • 89 citations

Histochemical and autoradiographic study of the cultured rat visceral yolk sac

1986 • 75 citations

Über Selbstdifferenzierung und Induktion bei dem Seeigelkeim

1929 • 73 citations

Über gefälleabhängige Bildungen des Insektensegmentes

1966 • 39 citations

Developmental expression and tissue distribution of the lethal (2) giant larvae protein of Drosophila melanogaster.

1986 • 38 citations

A model of gradient interpretation based on morphogen binding

1978 • 24 citations

The mechanics of sea urchin development.

1950 • 22 citations

Individuality in organisms

1915 • 20 citations

Isolation and amino acid sequence of a morphogenetic peptide from hydra

1982 • 20 citations