Feedback regulation ofDrosophilaBMP signaling by the novel extracellular protein Larval Translucida

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

DEVELOPMENT IN DROSOPHILA MELANOGASTER

1927 • 2,909 citations

Mosaic Analysis with a Repressible Cell Marker for Studies of Gene Function in Neuronal Morphogenesis

1999 • 2,521 citations

Analysis of genetic mosaics in developing and adult Drosophila tissues

1993 • 2,029 citations

Bone morphogenetic proteins: multifunctional regulators of vertebrate development.

1996 • 1,959 citations

Fibroblast growth factors.

2001 • 1,946 citations

Hedgehog Signaling in Development and Cancer

2008 • 1,013 citations

Minutes: Mutants of Drosophila autonomously affecting cell division rate

1975 • 940 citations

Direct and Long-Range Action of a DPP Morphogen Gradient

1996 • 896 citations

Organizing activity of wingless protein in Drosophila

1993 • 852 citations

A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family

1987 • 756 citations

Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster.

1995 • 672 citations

Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing

1996 • 629 citations

Gradient Formation of the TGF-β Homolog Dpp

2000 • 606 citations

Induction of Drosophila eye development by Decapentaplegic

1997 • 567 citations

Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing

1995 • 489 citations

Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling

1999 • 474 citations

Dpp Gradient Formation in the Drosophila Wing Imaginal Disc

2000 • 453 citations

Daughters against dpp modulates dpp organizing activity in Drosophila wing development

1997 • 426 citations

Kinetics of Morphogen Gradient Formation

2007 • 398 citations

The Decapentaplegic morphogen gradient: from pattern formation to growth regulation

2007 • 377 citations

Production of a DPP Activity Gradient in the Early Drosophila Embryo through the Opposing Actions of the SOG and TLD Proteins

1997 • 350 citations

The Drosophila rhomboid gene mediates the localized formation of wing veins and interacts genetically with components of the EGF-R signaling pathway.

1993 • 320 citations

Characterization and relationship of dpp receptors encoded by the saxophone and thick veins genes in Drosophila

1994 • 317 citations

Drosophila Dpp Morphogen Movement Is Independent of Dynamin-Mediated Endocytosis but Regulated by the Glypican Members of Heparan Sulfate Proteoglycans

2004 • 297 citations

Drosophila Dpp signaling is mediated by the punt gene product: A dual ligand-binding type II receptor of the TGFβ receptor family

1995 • 275 citations

Notch signaling in development and disease

2004 • 261 citations

Potent Ectopic Bone-Inducing Activity of Bone Morphogenetic Protein-4/7 Heterodimer

1995 • 259 citations

spalt encodes an evolutionarily conserved zinc finger protein of novel structure which provides homeotic gene function in the head and tail region of the Drosophila embryo.

1994 • 246 citations

HSPG Modification by the Secreted Enzyme Notum Shapes the Wingless Morphogen Gradient

2002 • 238 citations

Drosophilaglypicans control the cell-to-cell movement of Hedgehog by a dynamin-independent process

2004 • 237 citations

A gene complex acting downstream of dpp in Drosophila wing morphogenesis

1996 • 232 citations

The Fgf Families in Humans, Mice, and Zebrafish: Their Evolutional Processes and Roles in Development, Metabolism, and Disease

2007 • 217 citations

Control of the Gene optomotor-blind in Drosophila Wing Development by decapentaplegic and wingless

1996 • 206 citations

The extracellular regulation of bone morphogenetic protein signaling

2009 • 199 citations

Pattern formation in the Drosophila wing: The development of the veins

2003 • 194 citations

Dally regulates Dpp morphogen gradient formation by stabilizing Dpp on the cell surface

2007 • 190 citations

Extrusion and Death of DPP/BMP-Compromised Epithelial Cells in the Developing Drosophila Wing

2005 • 187 citations

Wing formation in Drosophila melanogaster requires decapentaplegic gene function along the anterior-posterior compartment boundary

1990 • 170 citations

The BMP-Binding Protein Crossveinless 2 Is a Short-Range, Concentration-Dependent, Biphasic Modulator of BMP Signaling in Drosophila

2008 • 163 citations

Crossveinless 2 contains cysteine-rich domains and is required for high levels of BMP-like activity during the formation of the cross veins in Drosophila

2000 • 163 citations

Cellular Trafficking of the Glypican Dally-like Is Required for Full-Strength Hedgehog Signaling and Wingless Transcytosis

2008 • 155 citations

Evolution of the Wnt Pathways

2008 • 154 citations

Extrusion of Cells with Inappropriate Dpp Signaling from Drosophila Wing Disc Epithelia

2005 • 152 citations

The glypican Dally-like is required for Hedgehog signalling in the embryonic epidermis ofDrosophila

2003 • 142 citations

Early origin of the bilaterian developmental toolkit

2009 • 136 citations

Control of Dpp morphogen signalling by a secreted feedback regulator

2010 • 136 citations

The Core Protein of Glypican Dally-Like Determines Its Biphasic Activity in Wingless Morphogen Signaling

2009 • 107 citations

Growth regulation by Dpp: an essential role for Brinker and a non-essential role for graded signaling levels

2008 • 107 citations

Processing of the Drosophila Sog protein creates a novel BMP inhibitory activity

2000 • 103 citations

Biglycan is a new extracellular component of the Chordin–BMP4 signaling pathway

2005 • 99 citations

Tsukushi Functions as an Organizer Inducer by Inhibition of BMP Activity in Cooperation with Chordin

2004 • 99 citations

A conserved activation element in BMP signaling during Drosophila development

2009 • 97 citations

The crossveinless gene encodes a new member of the Twisted gastrulation family of BMP-binding proteins which, with Short gastrulation, promotes BMP signaling in the crossveins of the Drosophila wing

2005 • 93 citations

Behind the Official Optimism, Flawed Projections

1996 • 89 citations

Lumenal Transmission of Decapentaplegic in Drosophila Imaginal Discs

2002 • 87 citations

Genetic Analysis of the Bone Morphogenetic Protein-Related Gene, gbb, Identifies Multiple Requirements During Drosophila Development

1999 • 84 citations

Dpp and Gbb exhibit different effective ranges in the establishment of the BMP activity gradient critical for Drosophila wing patterning

2006 • 82 citations

Long-range Dpp signaling is regulated to restrict BMP signaling to a crossvein competent zone

2005 • 81 citations

Repression of Dpp Targets by Binding of Brinker to Mad Sites

2001 • 76 citations

Matching catalytic activity to developmental function: Tolloid-related processes Sog in order to help specify the posterior crossvein in theDrosophilawing

2005 • 74 citations

The Drosophila DPP signal is produced by cleavage of its proprotein at evolutionary diversified furin-recognition sites

2009 • 64 citations

Interactions between the Notch, EGFR, and decapentaplegic signaling pathways regulate vein differentiation during Drosophila pupal wing development

2005 • 63 citations

mtv shapes the activity gradient of the Dpp morphogen through regulation of thickveins

2001 • 62 citations

Dpp-responsive Silencers Are Bound by a Trimeric Mad-Medea Complex

2005 • 59 citations

crossveinless defines a new family of Twisted‐gastrulation‐like modulators of bone morphogenetic protein signalling

2005 • 44 citations

Drosophila Tbx6-related gene, Dorsocross, mediates high levels of Dpp and Scw signal required for the development of amnioserosa and wing disc primordium

2003 • 41 citations

Interplay between Drosophila Bloom's syndrome helicase and Ku autoantigen during nonhomologous end joining repair of P element-induced DNA breaks

2004 • 36 citations

The Drosophila LEM-domain protein MAN1 antagonizes BMP signaling at the neuromuscular junction and the wing crossveins

2009 • 25 citations

Bio-intensive Farming and Community Animation for Food Security and Sustainable Livelihoods

2001 • 20 citations

CaSpeR5, a family of Drosophila transgenesis and shuttle vectors with improved multiple cloning sites

2007 • 20 citations

Kekkon5 is an extracellular regulator of BMP signaling

2008 • 19 citations