Back to search

A changing morphogen gradient is interpreted by continuous transduction flow

Data up to Jan 2025

Published2002
Citations62
References39

Total Citations Per Year

Abstract

References (39)

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders

2000 • 2,354 citations

How cells read TGF-β signals

2000 • 1,843 citations

Controlling TGF-beta signaling.

2000 • 1,806 citations

Controlling TGF-β signaling

2000 • 1,522 citations

Expression of a xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction

1991 • 980 citations

Morphogen gradient interpretation

2001 • 738 citations

A transcriptional partner for MAD proteins in TGF-β signalling

1996 • 699 citations

Smad4 and FAST-1 in the assembly of activin-responsive factor

1997 • 567 citations

Responses of embryonic xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm

1992 • 486 citations

Dpp Gradient Formation in the Drosophila Wing Imaginal Disc

2000 • 453 citations

Xenopus Mad Proteins Transduce Distinct Subsets of Signals for the TGFβ Superfamily

1996 • 432 citations

Ubiquitin-dependent degradation of TGF-β-activated Smad2

1999 • 343 citations

Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif

2000 • 277 citations

Transforming Growth Factor β-Independent Shuttling of Smad4 between the Cytoplasm and Nucleus

2000 • 266 citations

Endogenous patterns of TGFβ superfamily signaling during early Xenopus development

2000 • 256 citations

Nodal Signaling in Early Vertebrate Embryos

2001 • 243 citations

Eomesodermin, a Key Early Gene in Xenopus Mesoderm Differentiation

1996 • 241 citations

Activation of muscle-specific actin genes in xenopus development by an induction between animal and vegetal cells of a blastula

1985 • 238 citations

The Interpretation of Position in a Morphogen Gradient as Revealed by Occupancy of Activin Receptors

1998 • 205 citations

Maternal β-catenin establishes a ‘dorsal signal’ in early Xenopus embryos

1996 • 191 citations

Efficient Hormone-Inducible Protein Function in Xenopus laevis

1995 • 190 citations

The development of animal cap cells in Xenopus: a measure of the start of animal cap competence to form mesoderm

1987 • 187 citations

Mode of action of VegT in mesoderm and endoderm formation

1999 • 186 citations

Problems and paradigms: Morphogens and pattern formation

1997 • 184 citations

Direct and continuous assessment by cells of their position in a morphogen gradient

1995 • 150 citations

Morphogen gradients: new insights from DPP

1999 • 116 citations

Timing of endogenous activin-like signals and regional specification of theXenopusembryo

2001 • 112 citations

The Role of FAST-1 and Smads in Transcriptional Regulation by Activin during Early Xenopus Embryogenesis

1999 • 111 citations

Chapter 16 Regulation of Protein Activities by Fusion to Steroid Binding Domains

1994 • 96 citations

Xenopus Smad4β Is the Co-Smad Component of Developmentally Regulated Transcription Factor Complexes Responsible for Induction of Early Mesodermal Genes

1999 • 92 citations

A quantitative analysis of signal transduction from activin receptor to nucleus and its relevance to morphogen gradient interpretation

1999 • 90 citations

TGF-β signalling pathways in early Xenopus development

2001 • 86 citations

The ALK-2 and ALK-4 activin receptors transduce distinct mesoderm-inducing signals during earlyXenopusdevelopment but do not co-operate to establish thresholds

1997 • 83 citations

Single cells can sense their position in a morphogen gradient

1999 • 77 citations

XSmad2 directly activates the activin-inducible, dorsal mesoderm gene XFKH1 in Xenopus embryos

1997 • 67 citations

Measurement of developmental time by cells of early embryos

1990 • 53 citations

The initiation of new gene transcription during Xenopus gastrulation requires immediately preceding protein synthesis

1987 • 47 citations

Xenopus Smad3 is specifically expressed in the chordoneural hinge, notochord and in the endocardium of the developing heart

2001 • 26 citations

Cited By (0)

Loading...
A changing morphogen gradient is interpreted by continuous transduction flow (2002) – Development | Metascience Observatory Explorer