Responses of embryonic xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm

Positional information and the spatial pattern of cellular differentiation

1969 • 2,957 citations

Appendix G: In Situ Hybridization: An Improved Whole-Mount Method for Xenopus Embryos

1991 • 2,082 citations

Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos

1992 • 1,176 citations

Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryos

1991 • 1,103 citations

Expression of a xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction

1991 • 980 citations

Mesoderm induction in early Xenopus embryos by heparin-binding growth factors

1987 • 953 citations

Synergistic induction of mesoderm by FGF and TGF-β and the identification of an mRNA coding for FGF in the early xenopus embryo

1987 • 883 citations

Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid

1991 • 799 citations

Identification of a potent Xenopus mesoderm-inducing factor as a homologue of activin A

1990 • 660 citations

Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing center

1991 • 651 citations

Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures

1990 • 600 citations

Vital dye mapping of the gastrula and neurula of Xenopus laevis

1976 • 576 citations

Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development

1992 • 573 citations

Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate

1990 • 508 citations

Injected Wnt RNA induces a complete body axis in Xenopus embryos

1991 • 501 citations

DVR-4 (Bone Morphogenetic Protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction

1992 • 488 citations

The formation of the mesoderm in urodelean amphibians

1969 • 472 citations

A community effect in animal development

1988 • 388 citations

The LIM domain-containing homeo box gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos.

1992 • 371 citations

The Presence of Fibroblast Growth Factor in the Frog Egg: Its Role as a Natural Mesoderm Inducer

1988 • 367 citations

Monoclonal antibodies identify blastemal cells derived from dedifferentiating muscle in newt limb regeneration

1984 • 353 citations

Organizer-Specific Homeobox Genes in Xenopus laevis Embryos

1991 • 349 citations

Mix.1, a homeobox mRNA inducible by mesoderm inducers, is expressed mostly in the presumptive endodermal cells of Xenopus embryos

1989 • 316 citations

Regional specification within the mesoderm of early embryos of Xenopus laevis

1987 • 286 citations

Mesoderm induction and mesoderm-inducing factors in early amphibian development

1989 • 274 citations

Dorsalization and neural induction: properties of the organizer in Xenopus laevis.

1983 • 267 citations

Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos

1989 • 264 citations

The formation of the mesoderm in urodelean amphibians

1973 • 247 citations

A novel, activin-inducible, blastopore lip-specific gene of Xenopus laevis contains a fork head DNA-binding domain.

1992 • 236 citations

Localized enhancement and repression of the activity of the TGF-P family member, decapentaplegic, is necessary for dorsal-ventral pattern formation in the Drosophila embryo

1992 • 222 citations

Retinoic acid modifies mesodermal patterning in early Xenopus embryos.

1991 • 221 citations

The biological effects of XTC-MIF: quantitative comparison with Xenopus bFGF

1990 • 220 citations

Differential activation of Xenopus homeo box genes by mesoderm-inducing growth factors and retinoic acid.

1990 • 199 citations

Pre-existent pattern in Xenopus animal pole cells revealed by induction with activin

1991 • 194 citations

Bone morphogenetic protein 4 (BMP-4), a member of the TGF-β family, in early embryos of Xenopus laevis: analysis of mesoderm inducing activity

1991 • 167 citations

Bimodal and graded expression of theXenopushomeobox geneXhox3during embryonic development

1989 • 161 citations

Xwnt-8 modifies the character of mesoderm induced by bFGF in isolated Xenopus ectoderm.

1992 • 155 citations

Presence of activin (erythroid differentiation factor) in unfertilized eggs and blastulae of Xenopus laevis.

1991 • 151 citations

Chapter 20 Assays for Gene Function in Developing Xenopus Embryos

1991 • 149 citations

Presence of basic fibroblast growth factor in the early Xenopus embryo

1989 • 144 citations

Transcription of muscle-specific actin genes in early xenopus development: Nuclear transplantation and cell dissociation

1984 • 127 citations

The Xenopus XIHbox 6 homeo protein, a marker of posterior neural induction, is expressed in proliferating neurons

1990 • 126 citations

Growth Factors in Early Embryogenesis

1989 • 119 citations

Scale of body pattern adjusts to available cell number in amphibian embryos

1981 • 117 citations

Biochemical specificity of Xenopus notochord

1985 • 116 citations

The organization of mesodermal pattern inXenopus laevis:experiments using aXenopusmesoderm-inducing factor

1987 • 110 citations

ventral ectoderm of Xenopus forms neural tissue, including hindbrain, in response to activin

1992 • 105 citations

Mesoderm induction in Xenopus laevis: a quantitative study using a cell lineage label and tissue-specific antibodies

1985 • 105 citations

A labile period in the determination of the anterior-posterior axis during early neural development in Xenopus

1992 • 103 citations

The Use of Polyacrylamide as an Embedding Medium for Immunohistochemical Studies of Embryonic Tissues

1981 • 87 citations

Growth factors as morphogens: do gradients and thresholds establish body plan?

1991 • 86 citations

Epidermal growth factor and transforming growth factor-alpha in the development of epithelial-mesenchymal organs of the mouse.

1990 • 77 citations

Transcriptional regulation of a Xenopus embryonic epidermal keratin gene

1989 • 73 citations

Une conception nouvelle des bases physiologiques de la morphogénèse

1937 • 67 citations

Nuclear translocation of fibroblast growth factor during Xenopus mesoderm induction

1991 • 59 citations

Secretory and inductive properties of Drosophila wingless protein in Xenopus oocytes and embryos

1992 • 53 citations

A mesoderm-inducing factor produced by WEHI-3 murine myelomonocytic leukemia cells is activin A

1990 • 51 citations

Mesoderm-inducing factors and Spemann’s organiser phenomenon in amphibian development

1989 • 45 citations

9 The Role of Growth Factors in Embryonic Induction in Amphibians

1990 • 42 citations

Xenopushomeobox-containing cDNAs expressed in early development

1988 • 42 citations

Axis Determination in Insect Embryos

2007 • 42 citations

A third striated muscle actin gene is expressed during early development in the amphibian Xenopus laevis

1988 • 37 citations

Expression of the Xhox3 Homeobox Protein in Xenopus Embryos: Blocking Its Early Function Suggests the Requirement of Xhox3 for Normal Posterior Development

1991 • 35 citations

Ciba Foundation Symposium 144 ‐ Cellular Basis of Morphogenesis

2007 • 1 citations

Deleted Work

1955 • 0 citations