Antagonistic action of Bicoid and the repressor Capicua determines the spatial limits of Drosophila head gene expression domains

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

Positional information and the spatial pattern of cellular differentiation

1969 • 2,957 citations

An optimized transgenesis system for Drosophila using germ-line-specific φC31 integrases

2007 • 1,874 citations

The origin of pattern and polarity in the Drosophila embryo

1992 • 1,367 citations

The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner

1988 • 1,022 citations

A gradient of bicoid protein in Drosophila embryos

1988 • 1,015 citations

Morphogen gradient interpretation

2001 • 738 citations

The role of localization of bicoid RNA in organizing the anterior pattern of the Drosophila embryo.

1988 • 736 citations

The gradient morphogen bicoid is a concentration-dependent transcriptional activator

1989 • 655 citations

Gal4 in the Drosophila female germline

1998 • 641 citations

Transcription Factors Bind Thousands of Active and Inactive Regions in the Drosophila Blastoderm

2008 • 495 citations

Predicting expression patterns from regulatory sequence in Drosophila segmentation

2008 • 495 citations

Determination of spatial domains of zygotic gene expression in the Drosophila embryo by the affinity of binding sites for the bicoid morphogen

1989 • 432 citations

Fusion between CIC and DUX4 up-regulates PEA3 family genes in Ewing-like sarcomas with t(4;19)(q35;q13) translocation

2006 • 422 citations

Organization of anterior pattern in the Drosophila embryo by the maternal gene bicoid

1986 • 386 citations

Regulation of the Drosophila segmentation gene hunchback by two maternal morphogenetic centres

1988 • 366 citations

Cis- acting sequences responsible for anterior localization of bicoid mRNA in Drosophila embryos

1988 • 346 citations

DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila

1998 • 309 citations

From gradients to stripes in Drosophila embryogenesis: filling in the gaps

1996 • 260 citations

Transcriptional Control in the Segmentation Gene Network of Drosophila

2004 • 254 citations

Relief of gene repression by Torso RTK signaling: role of capicua in Drosophila terminal and dorsoventral patterning

2000 • 231 citations

Activation of posterior gap gene expression in the Drosophila blastoderm

1995 • 201 citations

The role of binding site cluster strength in Bicoid-dependent patterning in Drosophila

2005 • 177 citations

Interactions of the Drosophila gap gene giant with maternal and zygotic pattern-forming genes

1991 • 152 citations

Formation of thebicoidmorphogen gradient: an mRNA gradient dictates the protein gradient

2009 • 147 citations

The Dichaete gene of Drosophila melanogaster encodes a SOX-domain protein required for embryonic segmentation

1996 • 142 citations

Isolation, structure, and expression of labial, a homeotic gene of the Antennapedia Complex involved in Drosophila head development.

1989 • 132 citations

A MAPK docking site is critical for downregulation of Capicua by Torso and EGFR RTK signaling

2007 • 122 citations

bicoid and the terminal system activate tailless expression in the early Drosophila embryo

1992 • 121 citations

The torso response element binds GAGA and NTF-1/Elf-1, and regulates tailless by relief of repression.

1995 • 118 citations

Down-regulation of the Drosophila morphogen bicoid by the torso receptor-mediated signal transduction cascade

1993 • 116 citations

Bicoid cooperative DNA binding is critical for embryonic patterning in Drosophila

2005 • 113 citations

Three maternal coordinate systems cooperate in the patterning of the Drosophila head

1994 • 105 citations

Molecular structure and spatial expression of a homeobox gene from the labial region of the Antennapedia-complex.

1988 • 104 citations

Anterior-posterior positional information in the absence of a strong Bicoid gradient

2009 • 97 citations

Nuclear Trapping Shapes the Terminal Gradient in the Drosophila Embryo

2008 • 88 citations

Targeting gene expression to the head: the Drosophila orthodenticle gene is a direct target of the Bicoid morphogen

1998 • 86 citations

NEW EMBO MEMBER'S REVIEW: In and out of Torso RTK signalling

2003 • 85 citations

Torso signalling regulates terminal patterning in Drosophila by antagonising Groucho-mediated repression

1997 • 84 citations

orthodenticle regulation during embryonic head development in Drosophila

1996 • 63 citations

Functions and mechanisms of receptor tyrosine kinase Torso signaling: Lessons from Drosophila embryonic terminal development

2005 • 55 citations

Trans- and cis-acting requirements for blastodermal expression of the head gap gene buttonhead

1995 • 50 citations

Phosphorylation of Bicoid on MAP-kinase sites: contribution to its interaction with the torso pathway

2000 • 46 citations

Identical transacting factor requirement for knirps and knirps-related gene expression in the anterior but not in the posterior region of the Drosophila embryo

1994 • 45 citations

Drosophila goosecoid participates in neural development but not in body axis formation.

1996 • 43 citations

Interaction of gap genes in the Drosophila head: tailless regulates expression of empty spiracles in early embryonic patterning and brain development

2001 • 33 citations

Homeobrain, a novel paired-like homeobox gene is expressed in the Drosophila brain

2000 • 30 citations

High Bicoid levels render the terminal system dispensable for Drosophila head development

2000 • 27 citations

Drosophila female sterile (1) homeotic is a multifunctional transcriptional regulator that is modulated by Ras signaling

2008 • 26 citations

Neither the homeodomain nor the activation domain of Bicoid is specifically required for its down-regulation by the Torso receptor tyrosine kinase cascade

1996 • 26 citations

Tramtrack69 is required for the early repression of tailless expression

2002 • 25 citations

Genetic regulation of CNC expression in the pharnygeal primordia ofDrosophila blastoderm embryos

1993 • 22 citations