Complex Regulation of cyp26a1 Creates a Robust Retinoic Acid Gradient in the Zebrafish Embryo

Stages of embryonic development of the zebrafish

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Patterning the Vertebrate Neuraxis

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Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos

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Retinoic acid causes an anteroposterior transformation in the developing central nervous system

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Cloning of the zebrafishkrox-20gene (krx-20) and its expression during hindbrain development

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Chapter 6 Positional Information and Pattern Formation

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Positional Information and Pattern Formation

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The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures

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A morphogen gradient of Wnt/β-catenin signalling regulates anteroposterior neural patterning inXenopus

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Robustness of the BMP morphogen gradient in Drosophila embryonic patterning

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Retinoic acid alters hindbrain Hox code and induces transformation of rhombomeres 2/3 into a 4/5 identity

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Expression of the zebrafish paired box gene pax[zf-b] during early neurogenesis

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The retinoic acid-inactivating enzyme CYP26 is essential for establishing an uneven distribution of retinoic acid along the anterio-posterior axis within the mouse embryo

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Do Morphogen Gradients Arise by Diffusion?

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Retinoic acid synthesis and hindbrain patterning in the mouse embryo

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The zebrafishnecklessmutation reveals a requirement forraldh2in mesodermal signals that pattern the hindbrain

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Identification of a retinoic acid-sensitive period during primary axis formation in Xenopus laevis.

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Vitamin A-deficient quail embryos have half a hindbrain and other neural defects

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Positional information revisited

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Regulation of Retinoic Acid Distribution Is Required for Proximodistal Patterning and Outgrowth of the Developing Mouse Limb

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Self-Enhanced Ligand Degradation Underlies Robustness of Morphogen Gradients

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Caudalization of neural fate by tissue recombination and bFGF

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CYP306A1, a Cytochrome P450 Enzyme, Is Essential for Ecdysteroid Biosynthesis in the Prothoracic Glands of Bombyx and Drosophila

2004 • 288 citations

Distinct roles for Fgf, Wnt and retinoic acid in posteriorizing the neural ectoderm

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Initiation of Rhombomeric Hoxb4 Expression Requires Induction by Somites and a Retinoid Pathway

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Retinoid X receptors: X-ploring their (patho)physiological functions

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Retinoic acid signalling links left–right asymmetric patterning and bilaterally symmetric somitogenesis in the zebrafish embryo

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Zebrafish hox genes: genomic organization and modified colinear expression patterns in the trunk

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Retinoids and Hox genes

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Dynamic Patterns of Retinoic Acid Synthesis and Response in the Developing Mammalian Heart

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Specification of the Anteroposterior Neural Axis through Synergistic Interaction of the Wnt Signaling Cascade withnogginandfollistatin

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Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development

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Hindbrain patterning involves graded responses to retinoic acid signalling

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Pre-Steady-State Decoding of the Bicoid Morphogen Gradient

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A caudorostral wave of RALDH2 conveys anteroposterior information to the cardiac field

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The DHR96 nuclear receptor regulates xenobiotic responses in Drosophila

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Vitamin A Deficiency Results in the Dose-Dependent Acquisition of Anterior Character and Shortening of the Caudal Hindbrain of the Rat Embryo

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Retinoic Acid-Mediated Gene Expression in Transgenic Reporter Zebrafish

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Shifting boundaries of retinoic acid activity control hindbrain segmental gene expression

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Xenopus Sprouty2 inhibits FGF-mediated gastrulation movements but does not affect mesoderm induction and patterning

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Feedback mechanisms regulate retinoic acid production and degradation in the zebrafish embryo

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Sharp developmental thresholds defined through bistability by antagonistic gradients of retinoic acid and FGF signaling

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The control of morphogen signalling: Regulation of the synthesis and catabolism of retinoic acid in the developing embryo

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Consequences of Hox gene duplication in the vertebrates: an investigation of the zebrafish Hox paralogue group 1 genes

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Retinoic acid-metabolizing enzyme Cyp26a1 is essential for determining territories of hindbrain and spinal cord in zebrafish

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Cyp12a4 confers lufenuron resistance in a natural population of Drosophila melanogaster

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Dynamic and sequential patterning of the zebrafish posterior hindbrain by retinoic acid

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Retinoic acid signaling and the evolution of chordates

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Endocytosis Controls Spreading and Effective Signaling Range of Fgf8 Protein

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Multiple points of interaction between retinoic acid and FGF signaling during embryonic axis formation

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Retinoids regulate the anterior expression boundaries of 5' Hoxb genes in posterior hindbrain

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Hindbrain respecification in the retinoid-deficient quail

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Characterization of concentration gradients of a morphogenetically active retinoid in the chick limb bud.

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Requirement of mesodermal retinoic acid generated by Raldh2 for posterior neural transformation

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Initial anteroposterior pattern of the zebrafish central nervous system is determined by differential competence of the epiblast

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Inhibition of mouse cytosolic aldehyde dehydrogenase by 4-(diethylamino)benzaldehyde

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Beyond the neckless phenotype: influence of reduced retinoic acid signaling on motor neuron development in the zebrafish hindbrain

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Morphogen gradients in vertebrate limb development

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Structure-activity and dose-response relationships in the neural and behavioral teratogenesis of retinoids

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Graded retinoid responses in the developing hindbrain

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FGF signal regulates gastrulation cell movements and morphology through its target NRH

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Travelling gradients in interacting morphogen systems

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Accurate Reading of Morphogen Concentrations by Nuclear Receptors: a Formal Model of Complex Transduction Pathways

1996 • 22 citations

High Albumin Levels Restrict the Kinetics of 13-cis Retinoic Acid Uptake and Intracellular Isomerization to All-trans Retinoic Acid and Inhibit its Anti-Proliferative Effect on SZ95 Sebocytes

2002 • 21 citations

Retinoid Signaling in Vertebrate Limb Developmenta

1996 • 16 citations

Aggregation of a Distributed Source in Morphogen Gradient Formation

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Inhibition of Mouse and Human Class 1 Aldehyde Dehydrogenase by 4-(N,N-Dialkylamino)Benzaldehyde Compounds

1996 • 11 citations