Autocrine signaling involved in cell volume regulation: The role of released transmitters and plasma membrane receptors

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1997 • 1,550 citations

Cellular mechanotransduction: putting all the pieces together again

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G-protein-coupled receptors and cancer

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Molecular Basis of Mechanotransduction in Living Cells

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THE CELLULAR AND MOLECULAR RESPONSE OF CARDIAC MYOCYTES TO MECHANICAL STRESS

1997 • 876 citations

Molecular Physiology and Pathophysiology of Electroneutral Cation-Chloride Cotransporters

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Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures

1990 • 689 citations

Diversity of the mammalian sodium/proton exchanger SLC9 gene family

2004 • 637 citations

Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4

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Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival

1998 • 574 citations

Mechanisms of Release of Nucleotides and Integration of Their Action as P2X- and P2Y-Receptor Activating Molecules

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Receptor‐mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD)

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G protein-coupled receptors sense fluid shear stress in endothelial cells

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Regulation of Cell Volume in Health and Disease

1995 • 450 citations

Extracellular ATP as a signaling molecule for epithelial cells

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Mechanisms and Significance of Cell Volume Regulation

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Amazing chloride channels: an overview

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Anisosmotic cell volume regulation: a comparative view

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The Na-K-Cl Cotransporter of Secretory Epithelia

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Cytotoxic edema: mechanisms of pathological cell swelling

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Cell volume regulation: osmolytes, osmolyte transport, and signal transduction

2003 • 362 citations

Calcium signaling in cell volume regulation

1992 • 349 citations

The EGF receptor as central transducer of heterologous signalling systems

1999 • 348 citations

Molecular and Functional Characterization of the Melastatin-related Cation Channel TRPM3

2003 • 345 citations

Autocrine signaling through ATP release represents a novel mechanism for cell volume regulation.

1996 • 328 citations

Mechanisms of glutamate release from astrocytes

2007 • 324 citations

The mechanosensitive nature of TRPV channels

2005 • 306 citations

Mechanical stress-initiated signal transductions in vascular smooth muscle cells

2000 • 281 citations

Modulation of membrane traffic by mechanical stimuli

2002 • 270 citations

Cellular and Molecular Pathways of Ischemic Neuronal Death

2002 • 263 citations

Astrocytic swelling in cerebral ischemia as a possible cause of injury and target for therapy

2005 • 257 citations

Physiological significance of volume-regulatory transporters

1999 • 244 citations

Actin remodeling to facilitate membrane fusion

2003 • 242 citations

Cellular volume homeostasis

2004 • 240 citations

P2 receptors: intracellular signaling

2006 • 238 citations

A Role for AQP5 in Activation of TRPV4 by Hypotonicity

2006 • 237 citations

Regulation of solute and water balance and cell volume in the central nervous system.

1992 • 233 citations

Potential for Control of Signaling Pathways via Cell Size and Shape

2006 • 226 citations

Activation of PDGF receptor α in vascular smooth muscle cells by mechanical stress

1998 • 216 citations

TRPM7 is a stretch- and swelling-activated cation channel involved in volume regulation in human epithelial cells

2006 • 213 citations

Volume-Dependent Atp-Conductive Large-Conductance Anion Channel as a Pathway for Swelling-Induced Atp Release

2001 • 212 citations

Protein tyrosine phosphorylation is involved in osmoregulation of ionic conductances.

1993 • 211 citations

TRPV4 exhibits a functional role in cell-volume regulation

2005 • 200 citations

Receptor-mediated glutamate release from volume sensitive channels in astrocytes

2005 • 198 citations

Regulation of a Transient Receptor Potential (TRP) Channel by Tyrosine Phosphorylation

2003 • 197 citations

ATP Released From Astrocytes During Swelling Activates Chloride Channels

2003 • 195 citations

Colocalization of ATP Release Sites and Ecto-ATPase Activity at the Extracellular Surface of Human Astrocytes

2003 • 195 citations

Cystic Fibrosis Transmembrane Conductance Regulator Facilitates ATP Release by Stimulating a Separate ATP Release Channel for Autocrine Control of Cell Volume Regulation

2001 • 195 citations

In defense of cell volume?

1993 • 194 citations

Regulation of the Cellular Content of the Organic Osmolyte Taurine in Mammalian Cells

2003 • 190 citations

Role of calcium in astrocyte volume regulation and in the release of ions and amino acids

1993 • 185 citations

Cell Volume Regulatory Ion Channels in Cell Proliferation and Cell Death

2007 • 184 citations

Brain Volume Regulation in Response to Hypo-osmolality and Its Correction

2006 • 183 citations

Physiological Regulation of ATP Release at the Apical Surface of Human Airway Epithelia

2006 • 183 citations

Voltage-dependent Anion Channel-1 (VDAC-1) Contributes to ATP Release and Cell Volume Regulation in Murine Cells

2004 • 177 citations

Biophysical, pharmacological, and functional characteristics of cloned and native mammalian two-pore domain K+ channels

2007 • 175 citations

Dual role of the TRPV4 channel as a sensor of flow and osmolality in renal epithelial cells

2007 • 174 citations

Functional TRPV4 channels are expressed in human airway smooth muscle cells

2004 • 173 citations

Mechanisms of Ammonia-Induced Astrocyte Swelling

2005 • 171 citations

Activation of the osmo-sensitive chloride conductance involves P21rho and is accompanied by a transient reorganization of the F-actin cytoskeleton.

1996 • 171 citations

New concepts in the mechanism of ammonia-induced astrocyte swelling

2007 • 168 citations

Cell volume regulation and swelling-activated chloride channels

2003 • 166 citations

Mitogen-Activated Protein and Tyrosine Kinases in the Activation of Astrocyte Volume-Activated Chloride Current

1998 • 166 citations

A role for ion channels in glioma cell invasion.

2006 • 166 citations

Hepatocellular ATP-binding Cassette Protein Expression Enhances ATP Release and Autocrine Regulation of Cell Volume

1997 • 165 citations

Src Homology 3 Binding Sites in the P2Y2 Nucleotide Receptor Interact with Src and Regulate Activities of Src, Proline-rich Tyrosine Kinase 2, and Growth Factor Receptors

2004 • 164 citations

A role for ion channels in glioma cell invasion

2005 • 162 citations

The Tyrosine Kinase p56lck Mediates Activation of Swelling-induced Chloride Channels in Lymphocytes

1998 • 161 citations

Astrocytic Swelling Due to Hypotonic or High K⁺Medium Causes Inhibition of Glutamate and Aspartate Uptake and Increases Their Release

1995 • 161 citations

Physiology and pathophysiology of Na⁺/H⁺exchange and Na⁺-K⁺-2Cl⁻cotransport in the heart, brain, and blood

2006 • 159 citations

Cell swelling‐induced ATP release is tightly dependent on intracellular calcium elevations

2004 • 154 citations

The actin cytoskeleton and neurotransmitter release: An overview

2000 • 153 citations

Mechanisms of glutamate release from astrocytes: gap junction “hemichannels”, purinergic receptors and exocytotic release

2004 • 153 citations

Volume-regulated Anion Channels Serve as an Auto/Paracrine Nucleotide Release Pathway in Aortic Endothelial Cells

2002 • 152 citations

Non-neuronal acetylcholine and urinary bladder urothelium

2007 • 152 citations

NAD(P)H Oxidase-derived H2O2 Signals Chloride Channel Activation in Cell Volume Regulation and Cell Proliferation

2004 • 145 citations

Mechanisms of Cell Volume Regulation in Hypo-osmolality

2006 • 144 citations

Potassium homeostasis in the ischemic brain

2005 • 138 citations

The Na/K pump, Cl ion, and osmotic stabilization of cells

2003 • 137 citations

Mechanical stress-initiated signal transduction in vascular smooth muscle cells in vitro and in vivo

2007 • 135 citations

Mechanisms Sensing and Modulating Signals Arising From Cell Swelling

2002 • 133 citations

Ion Channels and Transporters Involved in Cell Volume Regulation and Sensor Mechanisms

2004 • 131 citations

Direct Mechano-Stress Sensitivity of TRPM7 Channel

2007 • 130 citations

Swelling-Induced, Cftr-Independent Atp Release from a Human Epithelial Cell Line

1999 • 130 citations

Ca2+ Signaling, Intracellular pH and Cell Volume in Cell Proliferation

2005 • 125 citations

Isovolumetric regulation of isolated S2 proximal tubules in anisotonic media.

1986 • 125 citations

Roles of two types of anion channels in glutamate release from mouse astrocytes under ischemic or osmotic stress

2006 • 123 citations

Glial diffusion barriers during aging and pathological states

2001 • 121 citations

Membrane Stretch-Induced Activation of a TRPM4-Like Nonselective Cation Channel in Cerebral Artery Myocytes

2007 • 119 citations

Role of prostaglandins and leukotrienes in volume regulation by Ehrlich ascites tumor cells

1987 • 118 citations

ATP potently modulates anion channel-mediated excitatory amino acid release from cultured astrocytes

2002 • 116 citations

Neuronal versus glial cell swelling in the ischaemic retina

2005 • 114 citations

Phosphatidylinositol 3-Kinase Contributes to Cell Volume Regulation through Effects on ATP Release

1998 • 114 citations

Molecular and functional aspects of anionic channels activated during regulatory volume decrease in mammalian cells*

2002 • 114 citations

Stretch of β1 Integrin Activates an Outwardly Rectifying Chloride Current via FAK and Src in Rabbit Ventricular Myocytes

2003 • 113 citations

ATP regulates anion channel-mediated organic osmolyte release from cultured rat astrocytes via multiple Ca²⁺-sensitive mechanisms

2004 • 111 citations

Cyclic stretch activates ERK1/2 via G proteins and EGFR in alveolar epithelial cells

2002 • 111 citations

Diffusion properties of the brain in health and disease

2004 • 110 citations

Diversity of Cl− Channels

2005 • 110 citations

TNF-α and insulin, alone and synergistically, induce plasminogen activator inhibitor-1 expression in adipocytes

1999 • 109 citations

Release of ATP from retinal pigment epithelial cells involves both CFTR and vesicular transport

2004 • 107 citations

Cultured astrocytes express proteins involved in vesicular glutamate release

1997 • 106 citations

Pharmacological characterization of swelling-induced<scp>d</scp>-[³H]aspartate release from primary astrocyte cultures

1998 • 106 citations

Parathyroid Hormone-activated Volume-sensitive Calcium Influx Pathways in Mechanically Loaded Osteocytes

2000 • 105 citations

Adenosine and Adenine Nucleotides as Regulators of Cerebral Blood Flow: Roles of Acidosis, Cell Swelling, and KATP Channels

2004 • 104 citations

Swelling‐activated ion channels: functional regulation in cell‐swelling, proliferation and apoptosis

2006 • 103 citations

Involvement of Integrins in Osmosensing and Signaling toward Autophagic Proteolysis in Rat Liver

2003 • 103 citations

Volume-sensitive purinergic signaling in human hepatocytes

2000 • 103 citations

Cellular Function and Control of Volume-Regulated Anion Channels

2001 • 103 citations

Involvement of Rho‐kinase and tyrosine kinase in hypotonic stress‐induced ATP release in bovine aortic endothelial cells

2001 • 102 citations

The regulation of neurotransmitter secretion by protein kinase C

1998 • 101 citations

Cell swelling-induced ATP release and gadolinium-sensitive channels

2002 • 97 citations

Glutamate release by neurons evokes a purinergic inhibitory mechanism of osmotic glial cell swelling in the rat retina: Activation by neuropeptide Y

2006 • 97 citations

Regulation of taurine transport in Ehrlich ascites tumor cells

1993 • 94 citations

Influence of Calcium on Regulatory Volume Decrease: Role of Potassium Channels

2000 • 92 citations

Disruption of ionic and cell volume homeostasis in cerebral ischemia: The perfect storm

2007 • 89 citations

Swelling‐activated, cystic fibrosis transmembrane conductance regulator‐augmented ATP release and Cl⁻ conductances in murine C127 cells

2000 • 88 citations

IK channels are involved in the regulatory volume decrease in human epithelial cells

2003 • 87 citations

The role of volume-sensitive ion transport systems in regulation of epithelial transport

2006 • 86 citations

Na⁺/H⁺ exchangers and the regulation of volume

2006 • 86 citations

Mechanisms Counteracting Swelling in Brain Cells During Hyponatremia

2002 • 83 citations

EGFR Kinase Regulates Volume-sensitive Chloride Current Elicited by Integrin Stretch via PI-3K and NADPH Oxidase in Ventricular Myocytes

2006 • 83 citations

Increased Vesicle Recycling in Response to Osmotic Cell Swelling

2003 • 82 citations

The role of the neutral amino acid transporter SNAT2 in cell volume regulation

2006 • 81 citations

Defining pathways of loss and secretion of chemical messengers from astrocytes

2004 • 80 citations

Amino acid current through anion channels in cultured human glial cells

1995 • 78 citations

The elusive sizer

2005 • 76 citations

Modulation of spontaneous quantal release of neurotransmitters in the hippocampus

2001 • 76 citations

Ca²⁺‐dependent ATP release from A549 cells involves synergistic autocrine stimulation by coreleased uridine nucleotides

2007 • 75 citations

Cholesterol modulates the volume-regulated anion current in Ehrlich-Lettre ascites cells via effects on Rho and F-actin

2006 • 75 citations

Modulation of Aqueous Humor Outflow by Ionic Mechanisms Involved in Trabecular Meshwork Cell Volume Regulation

2004 • 72 citations

Effect of arachidonic acid, fatty acids, prostaglandins, and leukotrienes on volume regulation in Ehrlich ascites tumor cells

1987 • 69 citations

Differential Effects of Tyrosine Kinase Inhibitors on Volume-sensitive Chloride Current in Human Atrial Myocytes

2004 • 68 citations

Vesicular exocytosis contributes to volume-sensitive ATP release in biliary cells

2004 • 68 citations

Astrocyte swelling leads to membrane unfolding, not membrane insertion

2006 • 67 citations

Cytotoxic Edema

2007 • 67 citations

Receptor-Mediated Facilitation of Cell Volume Regulation by Swelling-Induced ATP Release in Human Epithelial Cells.

2000 • 64 citations

Autocrine/paracrine stimulation of purinergic receptors in osteoblasts: Contribution of vesicular ATP release

2005 • 64 citations

Cell Volume-Regulated Cation Channels

2006 • 63 citations

Volume-dependent taurine release from cultured astrocytes requires permissive [Ca²⁺]_iand calmodulin

1999 • 63 citations

Regulation of swelling-activated Cl- current by angiotensin II signalling and NADPH oxidase in rabbit ventricle

2007 • 63 citations

Role of Phosphoinositide Hydrolysis in Astrocyte Volume Regulation

1993 • 62 citations

αVβ3 Integrin ligands enhance volume-sensitive calcium influx in mechanically stretched osteocytes

2006 • 61 citations

Modeling cell volume regulation in nonexcitable cells: the roles of the Na⁺ pump and of cotransport systems

1998 • 61 citations

Activation of the volume-sensitive chloride current in vascular endothelial cells requires a permissive intracellular Ca2+ concentration

1996 • 60 citations

The influence of cell volume changes on tumour cell proliferation

2003 • 59 citations

Cell Volume-Sensitive Chloride Channels: Phenotypic Properties and Molecular Identity

2006 • 59 citations

ATP-Conducting Maxi-Anion Channel: A New Player in Stress-Sensory Transduction

2004 • 59 citations

Osmotic cell swelling-induced ATP release mediates the activationof extracellular signal-regulated protein kinase (Erk)-1/2 but not the activation of osmo-sensitive anion channels

1999 • 58 citations

Evidence for Multidrug Resistance-1 P-Glycoprotein-dependent Regulation of Cellular ATP Permeability

2001 • 58 citations

Evidence for two mechanisms of amino acid osmolyte release from hippocampal slices

2001 • 57 citations

Cell swelling, seizures and spreading depression: An impedance study

2006 • 56 citations

Characterization of the hypo-osmolarity-induced Ca2+ response in cultured rat astrocytes

1997 • 56 citations

Human cervical cancer cells use Ca²⁺ signalling, protein tyrosine phosphorylation and MAP kinase in regulatory volume decrease

2001 • 55 citations

TRPM7 channel is sensitive to osmotic gradients in human kidney cells

2007 • 55 citations

Hypoosmolar conditions reduce extracellular volume fraction and enhance epileptiform activity in the CA3 region of the immature rat hippocampus

2006 • 55 citations

Sensors and Signal Transduction in the Activation of Cell Volume Regulatory Ion Transport Systems

1998 • 55 citations

Stress kinase p38 mediates EGFR transactivation by hyperosmolar concentrations of sorbitol

2002 • 54 citations

Sensors and Signal Transduction Pathways in Vertebrate Cell Volume Regulation

2006 • 52 citations

Evidence for Gd³⁺inhibition of membrane ATP permeability and purinergic signaling

1999 • 52 citations

Swelling-induced taurine release without chloride channel activity in Xenopus laevis oocytes expressing anion channels and transporters

2000 • 52 citations

Direct Demonstration of Exocytosis and Endocytosis in Single Mouse Juxtaglomerular Cells

1999 • 52 citations

Volume Expansion Stimulates p72 and p56 in Skate Erythrocytes

1999 • 52 citations

Pyruvate prevents hydrogen peroxide-induced apoptosis

1998 • 51 citations

Osmosensitive release of neurotransmitter amino acids: relevance and mechanisms.

2002 • 51 citations

Characterization of volume-sensitive taurine- and Cl(-)-permeable channels

1997 • 50 citations

Thrombin potently enhances swelling‐sensitive glutamate efflux from cultured astrocytes

2007 • 50 citations

Structure and pharmacology of swelling‐sensitive chloride channels, I_Cl,swell

2003 • 50 citations

Molecular basis of renal disease. Mechanisms and clinical significance of cell volume regulation

1998 • 50 citations

Control and maintenance of mammalian cell size.

2004 • 49 citations

Hypotonicity stimulates renal epithelial sodium transport by activating JNK via receptor tyrosine kinases

2007 • 48 citations

Extracellular ATP stimulates volume decrease inNecturus red blood cells

1999 • 48 citations

Cell Volume Regulatory Ion Transport in the Regulation of Cell Migration

2006 • 48 citations

Volume regulation following hypotonic shock in isolated crypts of mouse distal colon

1999 • 47 citations

Isosmotic modulation of cell volume and intracellular ion activities during stimulation of single exocrine cells

1994 • 47 citations

Regulation of Hormone Secretion by Acute Cell Volume Changes: Ca&lt;sup&gt;2+&lt;/sup&gt;-Independent Hormone Secretion

2000 • 47 citations

Efflux of osmolyte amino acids during isovolumic regulation in hippocampal slices

2000 • 47 citations

Reduction of phospholemman expression decreases osmosensitive taurine efflux in astrocytes

2001 • 46 citations

Regulatory volume decrease and associated osmolyte fluxes in cerebellar granule neurons are calcium independent

1997 • 46 citations

Activation of the volume-sensitive chloride current in vascular endothelial cells requires a permissive intracellular Ca

1996 • 46 citations

The Role of P2Y1 Purinergic Receptors and Cytosolic Ca2+ in Hypotonically Activated Osmolyte Efflux from a Rat Hepatoma Cell Line

2002 • 45 citations

Protein tyrosine kinase and protein phosphatase signaling pathways regulate volume-sensitive chloride currents in a nonpigmented ciliary epithelial cell line.

2002 • 45 citations

Hydrogen Peroxide Potentiates Volume-sensitive Excitatory Amino Acid Release via a Mechanism Involving Ca2+/Calmodulin-dependent Protein Kinase II

2004 • 45 citations

Regulatory volume decrease by cultured non-pigmented ciliary epithelial cells

1992 • 45 citations

Role of LTD 4 in the Regulatory Volume Decrease Response in Ehrlich Ascites Tumor Cells

1996 • 44 citations

Autocrine Regulation of Volume-sensitive Anion Channels in Airway Epithelial Cells by Adenosine

1999 • 42 citations

Osmotic Swelling Activates Intermediate-Conductance Cl- Channels in Human Intestinal Epithelial Cells.

1994 • 42 citations

Volume sensitive efflux of taurine in HEK293 cells overexpressing phospholemman

2000 • 41 citations

Osmotic Swelling‐Induced Changes in Cytosolic Calcium Do Not Affect Regulatory Volume Decrease in Rat Cultured Suspended Cerebellar Astrocytes

1998 • 41 citations

Characterization of electrically evoked [3H]-d-aspartate release from hippocampal slices

2001 • 40 citations

Water induces autocrine stimulation of tumor cell killing through ATP release and P2 receptor binding

2004 • 40 citations

Regulation of ClC-2 chloride channels in T84 cells by TGF-α

2001 • 39 citations

VRACs CARVe a Path for Novel Mechanisms of Communication in the CNS

2006 • 39 citations

Hypotonic treatment evokes biphasic ATP release across the basolateral membrane of cultured renal epithelia (A6)

2002 • 39 citations

Ca2+- and Volume-sensitive Chloride Currents Are Differentially Regulated by Agonists and Store-operated Ca2+ Entry

2005 • 39 citations

Osmolytes and Mechanisms Involved in Regulatory Volume Decrease Under Conditions of Sudden or Gradual Osmolarity Decrease

2003 • 38 citations

Exocytosis upon osmotic swelling in human epithelial cells

1992 • 38 citations

Calcium/calmodulin-modulated chloride and taurine conductances in cultured rat astrocytes

2002 • 37 citations

Epidermal growth factor receptor is activated by hyposmolarity and is an early signal modulating osmolyte efflux pathways in Swiss 3T3 fibroblasts

2004 • 37 citations

Activation of muscarinic cholinergic receptors enhances the volume‐sensitive efflux of myo‐inositol from SH‐SY5Y neuroblastoma cells

2003 • 37 citations

Purinergic signaling underlies CFTR control of human airway epithelial cell volume

2004 • 36 citations

Feed Forward Cycle of Hypotonic Stress-induced ATP Release, Purinergic Receptor Activation, and Growth Stimulation of Prostate Cancer Cells

2005 • 36 citations

Potentiation of the osmosensitive taurine release and cell volume regulation by cytosolic Ca²⁺ rise in cultured cerebellar astrocytes

2003 • 36 citations

Depolarization, exocytosis and amino acid release evoked by hyposmolarity from cortical synaptosomes

2004 • 36 citations

Early cellular swelling during cerebral ischemia in vivo is mediated by excitatory amino acids released from nerve terminals

1992 • 36 citations

Epidermal Growth Factor Receptor is a Common Element in the Signaling Pathways Activated by Cell Volume Changes in Isosmotic, Hyposmotic or Hyperosmotic Conditions

2005 • 35 citations

Participation Of Atp In Cell Volume Regulation In The Endothelium After Hypotonic Stress

2001 • 35 citations

Potentiation of regulatory volume decrease by P2U purinoceptors in HSG-PA cells

1996 • 35 citations

Extracellular ATP Activates a P2 Receptor in Necturus Erythrocytes During Hypotonic Swelling

2001 • 34 citations

Purinergic-independent Calcium Signaling Mediates Recovery from Hepatocellular Swelling

2001 • 34 citations

Secretagogue-induced RVD in HSY cells is due to K+ channels activated by Ca2+ and protein kinase C

1993 • 34 citations

Chloride Channels Regulate HIT Cell Volume but Cannot Fully Account for Swelling-Induced Insulin Secretion

2001 • 34 citations

Influence of protein kinases on the osmosensitive release of taurine from cerebellar granule neurons

2001 • 33 citations

Ca(2+)-mobilizing hormones potentiate hypotonicity-induced activation of ionic conductances in Intestine 407 cells

1994 • 33 citations

Hypotonic activation of volume-sensitive outwardly rectifying chloride channels in cultured PASMCs is modulated by SGK

2004 • 33 citations

The role of integrins in the modulation of neurotransmitter release from motor nerve terminals by stretch and hypertonicity

2003 • 32 citations

Substantia nigra osmoregulation: taurine and ATP involvement

2007 • 32 citations

Amino acids as osmolytes in the retina.

1999 • 31 citations

Activation of H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt;-Induced VSOR Cl&lt;sup&gt;-&lt;/sup&gt; Currents in HTC Cells Require Phospholipase Cγ1 Phosphorylation and Ca&lt;sup&gt;2+&lt;/sup&gt; Mobilisation

2007 • 31 citations

Calcium Mobilization Evoked by Hepatocellular Swelling Is Linked to Activation of Phospholipase Cγ

2002 • 31 citations

Volume changes and whole cell membrane currents activated during gradual osmolarity decrease in C6 glioma cells: contribution of two types of K⁺ channels

2004 • 30 citations

Calcium-dependent chloride current activated by hyposmotic stress in rat lacrimal acinar cells

1993 • 30 citations

ATP Release Triggered by Activation of the Ca²⁺-Activated K⁺ Channel in Human Airway Calu-3 Cells

2003 • 30 citations

Stimulation by caveolin-1 of the hypotonicity-induced release of taurine and ATP at basolateral, but not apical, membrane of Caco-2 cells

2005 • 30 citations

Ca²⁺‐sensing receptor‐mediated regulation of volume‐sensitive Cl⁻ channels in human epithelial cells

2000 • 29 citations

Neuronal swelling and surface area regulation: elevated intracellular calcium is not a requirement

1998 • 29 citations

Antagonistic regulation of swelling-activated Cl⁻current in rabbit ventricle by Src and EGFR protein tyrosine kinases

2005 • 29 citations

Problems in the understanding of cell volume regulation

1994 • 29 citations

Src Regulates Distinct Pathways for Cell Volume Control through Vav andPhospholipaseCγ

2005 • 29 citations

Upregulation of Swelling‐Activated Cl⁻ Channel Sensitivity to Cell Volume by Activation of EGF Receptors in Murine Mammary Cells

2003 • 29 citations

Leukotriene-D4 induced cell shrinkage in Ehrlich ascites tumor cells

1989 • 29 citations

Vesicular Exocytosis under Hypotonic Conditions Shows Two Distinct Populations of Dense Core Vesicles in Bovine Chromaffin Cells

2007 • 29 citations

Tyrosine kinases and amino acid efflux under hyposmotic and ischaemic conditions in the chicken retina

2002 • 29 citations

Mechanosensitive activation of K⁺ channel via phospholipase C‐induced depletion of phosphatidylinositol 4,5‐bisphosphate in B lymphocytes

2007 • 29 citations

Swelling-induced catecholamine secretion recorded from single chromaffin cells

1995 • 28 citations

Inhibition of volume-stimulated taurine efflux and tyrosine kinase activity in the skate red blood cell

2000 • 27 citations

Control of Brain Volume during Hypoosmolality and Hyperosmolality

2006 • 27 citations

Chloride and taurine effluxes occur by different pathways in skate erythrocytes

1996 • 27 citations

Isovolumetric regulation of C6 rat glioma cells in hyperosmotic media

1997 • 27 citations

Cell swelling increases intracellular calcium in Necturuserythrocytes

2002 • 27 citations

Osmotic swelling-provoked release of organic osmolytes in human intestinal epithelial cells

2004 • 27 citations

Hyposmotic shock stimulates insulin secretion by two distinct mechanisms. Studies with the βHC9 cell

2002 • 27 citations

Regulation of cardiac volume-sensitive chloride channel by focal adhesion kinase and Src kinase

2005 • 26 citations

Hypotonicity and Thrombin Activate Taurine Efflux in BC3H1 and C2C12Myoblasts That Is Down Regulated during Differentiation

1997 • 26 citations

Ca2+-activated IK1 Channels Associate with Lipid Rafts upon Cell Swelling and Mediate Volume Recovery

2007 • 26 citations

Subnanomolar Concentrations of Thrombin Enhance the Volume-Sensitive Efflux of Taurine from Human 1321N1 Astrocytoma Cells

2005 • 26 citations

Tyrosine kinases and osmolyte fluxes during hyposmotic swelling

2006 • 25 citations

Effect of somatostatin on cell volume, Cl- currents, and transepithelial Cl- transport in rat distal colon

1994 • 25 citations

Signal transduction mechanisms of K⁺‐Cl⁻ cotransport regulation and relationship to disease

2006 • 25 citations

Calcium regulates the mode of exocytosis induced by hypotonic shock in isolated neuronal presynaptic endings

2004 • 24 citations

Regulation of Volume-Sensitive Osmolyte Efflux from Human SH-SY5Y Neuroblastoma Cells following Activation of Lysophospholipid Receptors

2006 • 24 citations

The leukotriene D4 receptor blocker, SK&amp;F 104353, inhibits volume regulation in isolated crypts from the rat distal colon

1993 • 23 citations

Effects of extracellular nucleotides and their hydrolysis products on regulatory volume decrease of trout hepatocytes

2004 • 23 citations

Agonist-induced cytoplasmic volume changes in cultured rabbit parietal cells

2000 • 23 citations

Further evidence for the existence of a volume‐activated taurine efflux pathway in rat mammary tissue independent from volume‐sensitive Cl^– channels

2000 • 23 citations

KCNQ channels are involved in the regulatory volume decrease response in primary neonatal rat cardiomyocytes

2007 • 23 citations

Evidence for swelling-induced adenosine and adenine nucleotide release in rat cerebral cortex exposed to monocarboxylate-containing or hypotonic artificial cerebrospinal fluids

2002 • 22 citations

Stimulus-secretion coupling of hypotonicity-induced insulin release in BRIN-BD11 cells

2006 • 22 citations

Osmolarity-induced renin secretion from kidneys: evidence for readily releasable renin pools

2005 • 22 citations

The Role of Calcium in the Volume Regulation of Rat Lacrimal Acinar Cells

1998 • 22 citations

Ca2+-mediated Potentiation of the Swelling-induced Taurine Efflux from HeLa Cells: On the Role of Calmodulin and Novel Protein Kinase C Isoforms

2004 • 22 citations

Extracellular pH alkalinization by Cl⁻/HCO₃⁻exchanger is crucial for TASK2 activation by hypotonic shock in proximal cell lines from mouse kidney

2006 • 21 citations

Receptor Regulation of the Volume-Sensitive Efflux of Taurine and Iodide from Human SH-SY5Y Neuroblastoma Cells: Differential Requirements for Ca²⁺ and Protein Kinase C

2006 • 21 citations

Intracellular signalling involved in activation of the volume-sensitive K+ current in Ehrlich ascites tumour cells

2001 • 21 citations

Hyposmolarity‐induced ErbB4 phosphorylation and its influence on the non‐receptor tyrosine kinase network response in cultured cerebellar granule neurons

2005 • 21 citations

Effects of hypo‐osmotic stress on ATP release in isolated turbot (Scophthalmus maximus) hepatocytes

2006 • 21 citations

Cell Volume Induced Hormone Secretion: Studies on Signal Transduction and Specificity

2003 • 20 citations

Influence of protein tyrosine kinases on cell volume changeinduced taurine release

2002 • 20 citations

Reduced aspartate release from rat hippocampal synaptosomes loaded with Clostridial toxin light chain by electroporation: Evidence for an exocytotic mechanism

2006 • 20 citations

Extracellular ATP Activates Chloride and Taurine Conductances in Cultured Hippocampal Neurons

2003 • 19 citations

Thrombin potentiates volume-activated chloride currents in pulmonary artery endothelial cells

1997 • 19 citations

The effect of a hyposmotic shock and purinergic agonists on K+(Rb+) efflux from cultured human breast cancer cells

2005 • 18 citations

Involvement Of B‐50 (GAP‐43) Phosphorylation In The Modulation Of Transmitter Release By Protein Kinase C

2001 • 18 citations

Cell Volume and Peptide Hormone Secretion

2006 • 18 citations

Differential dependence of regulatory volume decrease behavior in rabbit corneal epithelial cells on MAPK superfamily activation

2007 • 18 citations

Role of Calcium in Volume-Activated Chloride Currents in a Mouse Cholangiocyte Cell Line

2007 • 18 citations

Activation of volume‐regulated Cl⁻ channels by ACh and ATP in Xenopus follicles

2000 • 18 citations

Neural control of hepatic osmolytes and parenchymal cell hydration

2004 • 18 citations

Pivotal role of integrin 0'5H1 in hypotonic stress‐ induced responses of human endothelium

2006 • 17 citations

Influence of CA2+ on K+ efflux during regulatory volume decrease in cultured astrocytes

1999 • 17 citations

Cytoplasmic localization and efflux of endogenous d-aspartate in pheochromocytoma 12 cells

2006 • 17 citations

Involvement of stretch-activated cation channels in hypotonically induced insulin secretion in rat pancreatic β-cells

2006 • 17 citations

Mechanisms of the ATP potentiation of hyposmotic taurine release in Swiss 3T3 fibroblasts

2004 • 17 citations

Isovolumetric regulation of rat glial cells during development and correction of hypo-osmolality

2000 • 16 citations

Extracellular adenosine modulates a volume-sensitive-like chloride conductance in immortalized rabbit DC1 cells

2001 • 16 citations

Properties of volume-sensitive Cl- channels in a human epithelial cell line.

1994 • 16 citations

Hypotonic stress activates BK channels in clonal kidney cells via purinergic receptors, presumably of the P2Y₁ subtype

2006 • 15 citations

Hyposmolarity evokes norepinephrine efflux from synaptosomes by a depolarization‐ and Ca²⁺‐dependent exocytotic mechanism

2005 • 14 citations

Activation of phospholipase D by osmotic cell swelling

2004 • 12 citations

Osmomechanical Regulation of Membrane Trafficking in Polarized Cells

2000 • 11 citations

Thrombin increases hyposmotic taurine efflux and accelerates % MathType!Translator!2!1!AMS LaTeX.tdl!TeX -- AMS-LaTeX! % MathType!MTEF!2!1!+- % feaaeaart1ev0aaatCvAUfeBSjuyZL2yd9gzLbvyNv2CaerbbjxAHX % garmWu51MyVXgatuuDJXwAK1uy0HwmaeHbfv3ySLgzG0uy0Hgip5wz % aebbnrfifHhDYfgasaacH8qrps0lbbf9q8WrFfeuY-Hhbbf9v8qqaq % Fr0xc9pk0xbba9q8WqFfea0-yr0RYxir-Jbba9q8aq0-yq-He9q8qq % Q8frFve9Fve9Ff0dmeaabaqaciGacaGaaeqabaWaaeWaeaaakeaaca % qGjbGaae4qaiaabMeadaqhaaWcbaGaae4CaiaabEhacaqGLbGaaeiB % …

2007 • 11 citations

Taurine in Submandibular Gland of the Rat: Effect of Muscarinic Drugs

2002 • 11 citations

Astrocyte Cellular Swelling

2004 • 11 citations

The Effect of Swelling on TRH and Oxytocin Secretion From Hypothalamic Structures

2006 • 11 citations

Hypotonicity-Induced ATP Release Is Potentiated by Intracellular Ca2+ and Cyclic AMP in Cultured Human Bronchial Cells

2003 • 10 citations

Osmoregulation of Taurine Efflux from Cultured Human Breast Cancer Cells: Comparison with Volume Activated Cl&lt;sup&gt;-&lt;/sup&gt; Efflux and Regulation by Extracellular ATP

2006 • 10 citations

Activation of Kinases upon Volume Changes: Role in Cellular Homeostasis

2006 • 9 citations

Prostanoid Receptors Regulate the Volume-Sensitive Efflux of Osmolytes from Murine Fibroblasts via a Cyclic AMP-Dependent Mechanism

2006 • 9 citations

Permissive role of calcium on regulatory volume decrease in freshly isolated mouse cholangiocytes

2007 • 8 citations

Modulators of Ion Channels Activated by Hypotonic Swelling in Cardiomyocytes: New Perspectives for Pharmacological Treatment of Life-Threatening Arrhythmias

2005 • 7 citations

Osmosensitive taurine release: does taurine share the same efflux pathway with chloride and other amino acid osmolytes?

2003 • 6 citations

Osmosensitive Taurine Release

2003 • 6 citations

Sensitizing effect of lysophosphatidic acid on Ca2+ response to hypotonic stress in cultured lens epithelial cells

1999 • 5 citations

Role of Calcium in Exocytosis Induced by Hypotonic Swelling

2005 • 5 citations

Histamine-Mediated Hyposmotic Stimulation of Gastric Acid Secretion

1989 • 4 citations

Role of actin microfilament in hyposmotic membrane stretch-induced increase in muscarinic current of guinea-pig gastric myocytes.

2003 • 3 citations