Upregulation of Swelling‐Activated Cl⁻ Channel Sensitivity to Cell Volume by Activation of EGF Receptors in Murine Mammary Cells

Growth factor signaling by receptor tyrosine kinases

1992 • 1,450 citations

Protein Tyrosine Kinase Structure and Function

2000 • 1,117 citations

PC12 Pheochromocytoma Cultures in Neurobiological Research

1982 • 728 citations

Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis

2000 • 707 citations

Volume expansion-sensing outward-rectifier Cl- channel: fresh start to the molecular identity and volume sensor

1997 • 652 citations

Cellular and molecular physiology of volume-sensitive anion channels

1996 • 620 citations

Receptor‐mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD)

2001 • 523 citations

CFTR Is a Conductance Regulator as well as a Chloride Channel

1999 • 436 citations

Mouse cells transformed by bovine papillomavirus contain only extrachromosomal viral DNA sequences.

1981 • 387 citations

Properties of volume-regulated anion channels in mammalian cells

1997 • 357 citations

Extracellular signal-regulated kinase and c-Jun NH2-terminal kinase activation by mechanical stretch is integrin-dependent and matrix-specific in rat cardiac fibroblasts.

1998 • 330 citations

Helper-independent transformation by unintegrated Harvey sarcoma virus DNA

1978 • 277 citations

Selective platelet-derived growth factor receptor kinase blockers reverse sis-transformation.

1994 • 272 citations

Tyrphostins. II. Heterocyclic and .alpha.-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases

1991 • 260 citations

Activation of the platelet-derived growth factor receptor by the bovine papillomavirus E5 transforming protein.

1991 • 224 citations

Ca2+ sensitivity of volume‐regulatory K+ and Cl‐ channels in cultured human epithelial cells.

1988 • 223 citations

Protein tyrosine phosphorylation is involved in osmoregulation of ionic conductances.

1993 • 211 citations

Volume‐regulatory Cl‐ channel currents in cultured human epithelial cells.

1992 • 185 citations

The bovine papillomavirus E5 transforming protein can stimulate the transforming activity of EGF and CSF-1 receptors

1989 • 176 citations

Activation of the osmo-sensitive chloride conductance involves P21rho and is accompanied by a transient reorganization of the F-actin cytoskeleton.

1996 • 171 citations

Mitogen-Activated Protein and Tyrosine Kinases in the Activation of Astrocyte Volume-Activated Chloride Current

1998 • 166 citations

The Tyrosine Kinase p56lck Mediates Activation of Swelling-induced Chloride Channels in Lymphocytes

1998 • 161 citations

Regulation of a swelling‐activated chloride current in bovine endothelium by protein tyrosine phosphorylation and G proteins

1998 • 160 citations

Differential expression of volume‐regulated anion channels during cell cycle progression of human cervical cancer cells

2000 • 160 citations

Tyrosine kinase activation is an immediate and essential step in hypotonic cell swelling-induced ERK activation and c-fos gene expression in cardiac myocytes.

1996 • 152 citations

Blockers of volume-activated Cl? currents inhibit endothelial cell proliferation

1995 • 134 citations

Blocking swelling‐activated chloride current inhibits mouse liver cell proliferation

2001 • 129 citations

K⁺ channel block‐induced mammalian neuroblastoma cell swelling: a possible mechanism to influence proliferation

1998 • 129 citations

Inhibition by mibefradil, a novel calcium channel antagonist, of Ca²⁺‐ and volume‐activated Cl⁻ channels in macrovascular endothelial cells

1997 • 123 citations

Stoichiometry of recombinant cystic fibrosis transmembrane conductance regulator in epithelial cells and its functional reconstitution into cells in vitro.

1994 • 122 citations

CFTR: Interacting With Everything?

2001 • 122 citations

Modulation of the Kv1.3 Potassium Channel by Receptor Tyrosine Kinases

1997 • 121 citations

Tyrosine protein kinase inhibitors prevent activation of cardiac swelling-induced chloride current

1995 • 105 citations

Golgi Alkalinization by the Papillomavirus E5 Oncoprotein

2000 • 103 citations

Growth Factor Receptor Tyrosine Kinases Acutely Regulate Neuronal Sodium Channels through the Src Signaling Pathway

1998 • 99 citations

Acute Suppression of Inwardly Rectifying Kir2.1 Channels by Direct Tyrosine Kinase Phosphorylation

1998 • 93 citations

Swelling‐activated, cystic fibrosis transmembrane conductance regulator‐augmented ATP release and Cl⁻ conductances in murine C127 cells

2000 • 88 citations

Specific interaction between the bovine papillomavirus E5 transforming protein and the beta receptor for platelet-derived growth factor in stably transformed and acutely transfected cells

1994 • 87 citations

Transformation-specific interaction of the bovine papillomavirus E5 oncoprotein with the platelet-derived growth factor receptor transmembrane domain and the epidermal growth factor receptor cytoplasmic domain

1993 • 81 citations

Single-channel properties of a volume-sensitive anion conductance. Current activation occurs by abrupt switching of closed channels to an open state.

1995 • 78 citations

Phloretin differentially inhibits volume‐sensitive and cyclic AMP‐activated, but not Ca‐activated, Cl⁻ channels

2001 • 78 citations

The bovine papillomavirus type 1 E5 transforming protein specifically binds and activates the beta-type receptor for the platelet-derived growth factor but not other related tyrosine kinase-containing receptors to induce cellular transformation

1994 • 71 citations

Platelet-derived growth factor receptor can mediate tumorigenic transformation by the bovine papillomavirus E5 protein.

1993 • 70 citations

Glibenclamide blocks volume-sensitive Cl⁻ channels by dual mechanisms

1998 • 69 citations

The tyrosine kinase p60c-src regulates the fast gate of the cystic fibrosis transmembrane conductance regulator chloride channel

1996 • 65 citations

Volume-regulated chloride conductance in the LNCaP human prostate cancer cell line

2000 • 64 citations

Osmosignalling in C6 glioma cells

1997 • 58 citations

Inhibition of volume‐regulated anion channels by expression of the cystic fibrosis transmembrane conductance regulator

1999 • 57 citations

Human cervical cancer cells use Ca²⁺ signalling, protein tyrosine phosphorylation and MAP kinase in regulatory volume decrease

2001 • 55 citations

Modulation of a voltage-activated potassium channel by peptide growth factor receptors

1994 • 48 citations

Modulation of volume-regulated anion channels by extra- and intracellular pH

1998 • 48 citations

Epidermal Growth Factor Activates Store-Operated Calcium Channels in Human Glomerular Mesangial Cells

2001 • 44 citations

Osmotic Swelling Activates Intermediate-Conductance Cl- Channels in Human Intestinal Epithelial Cells.

1994 • 42 citations

The EGFR Gene Family in Embryonic Cell Activities

1997 • 37 citations

Down-regulation of volume-sensitive Cl - channels by CFTR is mediated by the second nucleotide-binding domain

2002 • 36 citations

The platelet-derived growth factor ß receptor as a target of the bovine papillomavirus E5 protein

2000 • 35 citations

Extra- and Intracellular Proton-Binding Sites of Volume-Regulated Anion Channels

2000 • 34 citations

Ca(2+)-mobilizing hormones potentiate hypotonicity-induced activation of ionic conductances in Intestine 407 cells

1994 • 33 citations

Synergetic activation of outwardly rectifying Cl⁻ currents by hypotonic stress and external Ca²⁺ in murine osteoclasts

1999 • 33 citations

Platelet-Derived Growth Factor Receptor Can Mediate Tumorigenic Transformation by the Bovine Papillomavirus E5 Protein

1993 • 31 citations

Expression of Human Uterine Tissue-Type Plasminogen Activator in Mouse Cells Using BPV Vectors

1987 • 27 citations

Analysis of Mutant Platelet-Derived Growth Factor Receptors Expressed in PC12 Cells Identifies Signals Governing Sodium Channel Induction during Neuronal Differentiation

1997 • 24 citations

Dual role of ATP in supporting volume-regulated chloride channels in mouse fibroblasts

2000 • 24 citations

Probing the water permeability of ROMK1 and amphotericin B channels using Xenopus oocytes

1998 • 13 citations

Swelling and Ca 2+ -activated Anion Conductances in C127 Epithelial Cells Expressing WT and ΔF508-CFTR

1996 • 8 citations

Epidermal Growth Factor Reduces L-Type Voltage-Activated Calcium Current Density in GH<sub>4</sub>C<sub>1</sub> Rat Pituitary Cells

1997 • 7 citations