ATP-Conducting Maxi-Anion Channel: A New Player in Stress-Sensory Transduction

Extracellular ATP: effects, sources and fate

1986 • 1,666 citations

Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides

1993 • 1,259 citations

Structure and Function of the CFTR Chloride Channel

1999 • 977 citations

Paracrine regulation of the renal microcirculation

1996 • 740 citations

Volume expansion-sensing outward-rectifier Cl- channel: fresh start to the molecular identity and volume sensor

1997 • 652 citations

CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP

1995 • 647 citations

Cellular and molecular physiology of volume-sensitive anion channels

1996 • 620 citations

Receptor‐mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD)

2001 • 523 citations

Purinergic signalling: ATP release.

2001 • 505 citations

Extracellular ATP as a signaling molecule for epithelial cells

2003 • 448 citations

Signalling via ATP in the nervous system

1994 • 441 citations

Amazing chloride channels: an overview

2003 • 401 citations

Physiological Basis of Cystic Fibrosis: A Historical Perspective

1999 • 400 citations

Cell-to-cell spread of calcium signals mediated by ATP receptors in mast cells

1992 • 373 citations

The multidrug resistance (mdr1) gene product functions as an ATP channel.

1993 • 372 citations

Cell volume regulation: osmolytes, osmolyte transport, and signal transduction

2003 • 362 citations

Properties of volume-regulated anion channels in mammalian cells

1997 • 357 citations

The cystic fibrosis transmembrane conductance regulator is a dual ATP and chloride channel.

1994 • 354 citations

Synaptic corelease of ATP and GABA in cultured spinal neurons

1999 • 352 citations

ATP: an extracellular signaling molecule between neurons and glia

2000 • 338 citations

VDAC channels mediate and gate the flow of ATP: implications for the regulation of mitochondrial function

1997 • 337 citations

On the association between transmitter secretion and the release of adenine nucleotides from mammalian motor nerve terminals.

1975 • 333 citations

Autocrine signaling through ATP release represents a novel mechanism for cell volume regulation.

1996 • 328 citations

Deformation-induced ATP release from red blood cells requires CFTR activity

1998 • 288 citations

Macula densa cell signaling involves ATP release through a maxi anion channel

2003 • 274 citations

Adenosine 5′-Triphosphate: a P2-Purinergic Agonist in the Myocardium

2001 • 267 citations

CFTR-independent ATP release from epithelial cells triggered by mechanical stimuli

1997 • 263 citations

Cell to Cell Communication in Response to Mechanical Stress via Bilateral Release of Atp and Utp in Polarized Epithelia

2000 • 248 citations

Bioluminescence detection of ATP release mechanisms in epithelia

1998 • 242 citations

A release mechanism for stored ATP in ocular ciliary epithelial cells

1998 • 233 citations

Juxtaglomerular cell complex in the regulation of renal salt excretion

1998 • 230 citations

Volume-Dependent Atp-Conductive Large-Conductance Anion Channel as a Pathway for Swelling-Induced Atp Release

2001 • 212 citations

ATP Released From Astrocytes During Swelling Activates Chloride Channels

2003 • 195 citations

Cystic Fibrosis Transmembrane Conductance Regulator Facilitates ATP Release by Stimulating a Separate ATP Release Channel for Autocrine Control of Cell Volume Regulation

2001 • 195 citations

Failure of the Cystic Fibrosis Transmembrane Conductance Regulator to Conduct ATP

1996 • 184 citations

ATP as a Signaling Molecule: the Exocrine Focus

2003 • 180 citations

Hepatocellular ATP-binding Cassette Protein Expression Enhances ATP Release and Autocrine Regulation of Cell Volume

1997 • 165 citations

Cystic Fibrosis Transmembrane Conductance Regulator

2000 • 165 citations

Cystic Fibrosis Transmembrane Regulator-independent Release of ATP

1998 • 162 citations

Hf-W Isotopic Evidence for Rapid Accretion and Differentiation in the Early Solar System

1996 • 157 citations

Volume-regulated Anion Channels Serve as an Auto/Paracrine Nucleotide Release Pathway in Aortic Endothelial Cells

2002 • 152 citations

ATP Transport Through a Single Mitochondrial Channel, VDAC, Studied by Current Fluctuation Analysis

1998 • 148 citations

Cell surface measurements of ATP release from single pancreatic β cells using a novel biosensor technique

1998 • 147 citations

Mechanical strain-induced Ca²⁺waves are propagated via ATP release and purinergic receptor activation

2000 • 143 citations

ABC transporter-facilitated ATP conductive transport

1999 • 139 citations

Cloning and in situ localization of a brain-derived porin that constitutes a large-conductance anion channel in astrocytic plasma membranes.

1994 • 139 citations

Cystic Fibrosis and the Salt Controversy

1999 • 135 citations

Macula Densa Cell Signaling

2003 • 134 citations

Swelling-Induced, Cftr-Independent Atp Release from a Human Epithelial Cell Line

1999 • 130 citations

Evidence for secretory pathway localization of a voltage-dependent anion channel isoform

2000 • 130 citations

CFTR Cl- channel and CFTR-associated ATP channel: distinct pores regulated by common gates

1998 • 125 citations

Purified Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Does Not Function as an ATP Channel

1996 • 115 citations

Phosphatidylinositol 3-Kinase Contributes to Cell Volume Regulation through Effects on ATP Release

1998 • 114 citations

Cystic Fibrosis Transmembrane Conductance Regulator–associated ATP Release Is Controlled by a Chloride Sensor

1998 • 109 citations

Extracellular ATP and cAMP as Paracrine and Interorgan Regulators of Renal Function ATP Release Mechanisms, ATP Receptors and Purinergic Signalling along the Nephron

2001 • 103 citations

Involvement of Rho‐kinase and tyrosine kinase in hypotonic stress‐induced ATP release in bovine aortic endothelial cells

2001 • 102 citations

The increase in the intracellular Ca2+ concentration induced by mechanical stimulation is propagated via release of pyrophosphorylated nucleotides in mammary epithelial cells

1994 • 98 citations

CFTR Channels Expressed in CHO Cells Do Not Have Detectable ATP Conductance

1996 • 95 citations

Cystic Fibrosis Transmembrane Conductance Regulator-associated ATP and Adenosine 3′-Phosphate 5′-Phosphosulfate Channels in Endoplasmic Reticulum and Plasma Membranes

1997 • 90 citations

Cellular ATP release by the cystic fibrosis transmembrane conductance regulator

1996 • 89 citations

Swelling‐activated, cystic fibrosis transmembrane conductance regulator‐augmented ATP release and Cl⁻ conductances in murine C127 cells

2000 • 88 citations

Electrodiffusional ATP movement through the cystic fibrosis transmembrane conductance regulator

1998 • 82 citations

The effect of systemic hypoxia on interstitial and blood adenosine, AMP, ADP and ATP in dog skeletal muscle

2001 • 79 citations

Phloretin differentially inhibits volume‐sensitive and cyclic AMP‐activated, but not Ca‐activated, Cl⁻ channels

2001 • 78 citations

DNA transposition: From a black box to a color monitor

1995 • 75 citations

Regulation of an ATP‐conductive large‐conductance anion channel and swelling‐induced ATP release by arachidonic acid

2002 • 74 citations

“The Force Be with You”: ATP in Gut Mechanosensory Transduction

2003 • 71 citations

Mechanical stress induces release of ATP from Ehrlich ascites tumor cells

1999 • 67 citations

VDAC Channels Differentiate between Natural Metabolites and Synthetic Molecules

2002 • 67 citations

Acetylcholine and ATP are coreleased from the electromotor nerve terminals of Narcine brasiliensis by an exocytotic mechanism.

1990 • 64 citations

Plasma Membrane Voltage-dependent Anion Channel Mediates Antiestrogen-activated Maxi Cl– Currents in C1300 Neuroblastoma Cells

2003 • 63 citations

Osmotic cell swelling-induced ATP release mediates the activationof extracellular signal-regulated protein kinase (Erk)-1/2 but not the activation of osmo-sensitive anion channels

1999 • 58 citations

Evidence for Multidrug Resistance-1 P-Glycoprotein-dependent Regulation of Cellular ATP Permeability

2001 • 58 citations

Sensitivity of volume-sensitive Cl- conductance in human epithelial cells to extracellular nucleotides

1996 • 54 citations

Is the multidrug resistance an ATP channel? Abraham EH, Prat AG, Gerweck L, Seneveratne T, Arceci RJ, Kramer R, Guidotti G, Cantiello HF. The multidrug resistance (mdr1) gene product functions as an ATP channel. Proc Natl Acad Sci USA 1993;90: 312–316

1993 • 54 citations

Evidence for Gd³⁺inhibition of membrane ATP permeability and purinergic signaling

1999 • 52 citations

Extracellular ATP stimulates volume decrease inNecturus red blood cells

1999 • 48 citations

Autocrine Regulation of Volume-sensitive Anion Channels in Airway Epithelial Cells by Adenosine

1999 • 42 citations

Electrodiffusional ATP movement through CFTR and other ABC transporters

2001 • 39 citations

Voltage-dependent anion channel localises to the plasma membrane and peripheral but not perinuclear mitochondria

2003 • 37 citations

cAMP activates an ATP-permeable pathway in neonatal rat cardiac myocytes

2000 • 35 citations

Expression of Drosophila melanogaster P-glycoproteins is associated with ATP channel activity

1996 • 35 citations

Extra- and Intracellular Proton-Binding Sites of Volume-Regulated Anion Channels

2000 • 34 citations

CHARACTERISTICS OF MEMBRANE TRANSPORT PROCESSES OF MACULA DENSA CELLS

1997 • 32 citations

Upregulation of Swelling‐Activated Cl⁻ Channel Sensitivity to Cell Volume by Activation of EGF Receptors in Murine Mammary Cells

2003 • 29 citations

Effect of cAMP on intracellular and extracellular ATP content of Cl- -secreting epithelia and 3T3 fibroblasts.

1994 • 25 citations

Evidence for secretory pathway localization of a voltage-dependent anion channel isoform

2000 • 25 citations

cAMP-activated anion conductance is associated with expression of CFTR in neonatal mouse cardiac myocytes

2000 • 24 citations

CFTR Expression in C127 Cells Is Associated with Enhanced Cell Shrinkage and ATP Extrusion in Cl−-Free Medium

1996 • 20 citations

Osmotic cell swelling-induced ATP release mediates the activationof extracellular signal-regulated protein kinase (Erk)-1/2 but not the activation of osmo-sensitive anion channels

1999 • 19 citations

Anion Permeability and Conduction of Adenine Nucleotides Through a Chloride Channel in Cardiac Sarcoplasmic Reticulum

1999 • 17 citations