Activation of PDGF receptor α in vascular smooth muscle cells by mechanical stress

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

1989 • 4,279 citations

The MAPK signaling cascade

1995 • 3,300 citations

The stress-activated protein kinase subfamily of c-Jun kinases

1994 • 2,616 citations

The Regulation of AP-1 Activity by Mitogen-activated Protein Kinases

1995 • 2,441 citations

The mitogen-activated protein kinase signal transduction pathway

1993 • 2,174 citations

GROWTH FACTOR RECEPTOR TYROSINE KINASES

1988 • 1,841 citations

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

1990 • 1,592 citations

Flow Effects on Prostacyclin Production by Cultured Human Endothelial Cells

1985 • 1,237 citations

Activation of Mitogen-activated Protein Kinase by H2O2

1996 • 1,202 citations

Parallel signal processing among mammalian MAPKs

1995 • 1,015 citations

Haemodynamic shear stress activates a K+ current in vascular endothelial cells

1988 • 1,003 citations

Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element.

1993 • 638 citations

Integrin transmembrane signaling and cytoskeletal control

1995 • 616 citations

Isolation of a Novel Receptor cDNA Establishes the Existence of Two PDGF Receptor Genes

1989 • 610 citations

Hemodynamic forces are complex regulators of endothelial gene expression

1995 • 547 citations

Cell proliferation in human coronary arteries.

1990 • 532 citations

PDGF B-chain in neurons of the central nervous system, posterior pituitary, and in a transgenic model

1991 • 410 citations

A new vacuum-operated stress-providing instrument that applies static or variable duration cyclic tension or compression to cells in vitro

1985 • 402 citations

Mechanical strain induces growth of vascular smooth muscle cells via autocrine action of PDGF.

1993 • 368 citations

Age-related Decline in Mitogen-activated Protein Kinase Activity in Epidermal Growth Factor-stimulated Rat Hepatocytes

1996 • 351 citations

Role of integrins in cellular responses to mechanical stress and adhesion

1997 • 335 citations

Stimulation of Transcription Factors NFκB and AP1 in Endothelial Cells Subjected to Shear Stress

1994 • 271 citations

PDGF alpha- and beta-receptors activate unique and common signal transduction pathways.

1992 • 259 citations

Cyclic Strain–Induced Monocyte Chemotactic Protein-1 Gene Expression in Endothelial Cells Involves Reactive Oxygen Species Activation of Activator Protein 1

1997 • 246 citations

Control of hypertrophic versus hyperplastic growth of vascular smooth muscle cells

1989 • 223 citations

Human platelet-derived growth factor (PDGF): purification of PDGF-I and PDGF-II and separation of their reduced subunits.

1981 • 211 citations

Acute hypertension activates mitogen-activated protein kinases in arterial wall.

1996 • 200 citations

Activation of Mitogen-Activated Protein Kinases (ERK/JNK) and AP-1 Transcription Factor in Rat Carotid Arteries After Balloon Injury

1997 • 171 citations

Physical forces and the mammalian cell

1993 • 158 citations

Endothelial control of the cardiovascular system: recent advances

1996 • 151 citations

Nitric oxide induces heat-shock protein 70 expression in vascular smooth muscle cells via activation of heat shock factor 1.

1997 • 144 citations

Fluid shear stress stimulates platelet-derived growth factor expression in endothelial cells

1993 • 119 citations

Acute Hypertension Induces Heat-Shock Protein 70 Gene Expression in Rat Aorta

1995 • 113 citations

Culturing cells in a mechanically active environment.

1990 • 112 citations

Signal transduction in arteriosclerosis: mechanical stress-activated MAP kinases in vascular smooth muscle cells (review).

1998 • 98 citations

Activation of JNK/SAPK and ERK by Mechanical Strain in Vascular Smooth Muscle Cells Depends on Extracellular Matrix Composition

1997 • 98 citations

Shear Stress and Cyclic Strain Modulation of Gene Expression in Vascular Endothelial Cells

1995 • 92 citations

Antisense oligonucleotides for PDGF-B and its receptor inhibit mechanical strain-induced fetal lung cell growth

1995 • 86 citations

New perspectives in hypertension research. Potentials of vascular biology.

1994 • 81 citations

Phosphorylation of Tyrosine 720 in the Platelet-Derived Growth Factor α Receptor Is Required for Binding of Grb2 and SHP-2 but Not for Activation of Ras or Cell Proliferation

1996 • 69 citations

Discordant Activation of Stress-activated Protein Kinases or c-Jun NH2-terminal Protein Kinases in Tissues of Heat-stressed Mice

1997 • 67 citations

Vasopressin-induced heat shock protein expression in renal tubular cells.

1996 • 32 citations

Integration of hypertension research in the era of molecular biology

1995 • 16 citations

Behavioural medicine in cardiovascular disorders

1989 • 7 citations