Osmotic swelling-provoked release of organic osmolytes in human intestinal epithelial cells

Functional Significance of Cell Volume Regulatory Mechanisms

1998 • 1,871 citations

The extended protein kinase C superfamily

1998 • 1,544 citations

The superfamily of organic anion transporting polypeptides

2002 • 859 citations

Ion Channels and Their Functional Role in Vascular Endothelium

2001 • 850 citations

Cellular and molecular physiology of volume-sensitive anion channels

1996 • 620 citations

The role of cellular hydration in the regulation of cell function

1996 • 571 citations

Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter

1998 • 376 citations

Molecular basis of osmotic regulation

1995 • 371 citations

Excitatory amino acids directly depolarize rat brain astrocytes in primary culture

1984 • 358 citations

Volume-sensitive anion channels mediate swelling-activated inositol and taurine efflux

1993 • 331 citations

Protein tyrosine phosphorylation is involved in osmoregulation of ionic conductances.

1993 • 211 citations

Activation of the osmo-sensitive chloride conductance involves P21rho and is accompanied by a transient reorganization of the F-actin cytoskeleton.

1996 • 171 citations

The Tyrosine Kinase p56lck Mediates Activation of Swelling-induced Chloride Channels in Lymphocytes

1998 • 161 citations

Validation of the determination of amino acids in plasma by high-performance liquid chromatography using automated pre-column derivatization with o-phthaldialdehyde

1995 • 160 citations

The volume-sensitive organic osmolyte-anion channel VSOAC is regulated by nonhydrolytic ATP binding

1994 • 156 citations

Molecular Pharmacology of Organic Cation Transporters in Kidney

1999 • 153 citations

The organic anion transporter family: from physiology to ontogeny and the clinic

2001 • 153 citations

Role of Rho and Rho kinase in the activation of volume‐regulated anion channels in bovine endothelial cells

1999 • 140 citations

Swelling-Induced, Cftr-Independent Atp Release from a Human Epithelial Cell Line

1999 • 130 citations

Amino acid transport and cell volume regulation in Ehrlich ascites tumour cells.

1983 • 125 citations

Membrane transporters

2000 • 124 citations

Release of non‐neuronal acetylcholine from the isolated human placenta is mediated by organic cation transporters

2001 • 118 citations

Intracellular ionic strength regulates the volume sensitivity of a swelling-activated anion channel

1998 • 112 citations

Vascular effects of LPS in mice deficient in expression of the gene for inducible nitric oxide synthase

1998 • 105 citations

Cellular Function and Control of Volume-Regulated Anion Channels

2001 • 103 citations

Separate taurine and chloride efflux pathways activated during regulatory volume decrease

1999 • 97 citations

Amino Acid Osmolytes in Regulatory Volume Decrease and Isovolumetric Regulation in Brain Cells: Contribution and Mechanisms

2000 • 96 citations

Perspective: Molecular Identity of the Outwardly Rectifying, Swelling-activated Anion Channel: Time to Reevaluate pICln

1998 • 90 citations

Volume‐regulatory taurine release from a human lung cancer cell line

1993 • 75 citations

RhoA exerts a permissive effect on volume-regulated anion channels in vascular endothelial cells

2002 • 70 citations

Swelling-Activated Release of Excitatory Amino Acids in the Brain: Relevance for Pathophysiology

1998 • 69 citations

Taurine efflux and the regulation of cell volume in incubated slices of rat cerebral cortex

1994 • 67 citations

Swelling-activated efflux of taurine and other organic osmolytes in endothelial cells

1997 • 66 citations

Function and regulation of ATP-binding cassette transport proteins involved in hepatobiliary transport

2000 • 65 citations

Volume-dependent taurine release from cultured astrocytes requires permissive [Ca²⁺]_iand calmodulin

1999 • 63 citations

Osmotic cell swelling-induced ATP release mediates the activationof extracellular signal-regulated protein kinase (Erk)-1/2 but not the activation of osmo-sensitive anion channels

1999 • 58 citations

Evidence for two mechanisms of amino acid osmolyte release from hippocampal slices

2001 • 57 citations

Tyrosine phosphorylation modulates the osmosensitivity of volume‐dependent taurine efflux from glial cells in the rat supraoptic nucleus

2000 • 56 citations

Organic osmolyte channels in cell volume regulation in vertebrates

1999 • 47 citations

Organic cation transporter mRNA and function in the rat superior cervical ganglion

2002 • 45 citations

The Endothelial Volume-Regulated Anion Channel, VRAC

2000 • 44 citations

Osmotically regulated taurine content in rat renal inner medulla

1991 • 43 citations

Function and regulation of ATP-binding cassette transport proteins involved in hepatobiliary transport

2001 • 43 citations

How tonicity regulates gene expression.

1992 • 42 citations

Regulation of I _Cl,swell in neuroblastoma cells by G protein signaling pathways

2001 • 41 citations

Ca2+ and cAMP activate different chloride efflux pathways in HT-29.cl19A colonic epithelial cell line

1991 • 41 citations

Osmotic Swelling‐Induced Changes in Cytosolic Calcium Do Not Affect Regulatory Volume Decrease in Rat Cultured Suspended Cerebellar Astrocytes

1998 • 41 citations

Association of the Band 3 Protein with a Volume-Activated, Anion and Amino Acid Channel: A Molecular Approach

1997 • 39 citations

Organic osmolyte channels in cell volume regulation in vertebrates

1999 • 37 citations

Calcium/calmodulin-modulated chloride and taurine conductances in cultured rat astrocytes

2002 • 37 citations

Influence of protein kinases on the osmosensitive release of taurine from cerebellar granule neurons

2001 • 33 citations

Ca(2+)-mobilizing hormones potentiate hypotonicity-induced activation of ionic conductances in Intestine 407 cells

1994 • 33 citations

Intracellular ATP depletion inhibits swelling-induced d-[3H]aspartate release from primary astrocyte cultures

1999 • 32 citations

Amino acids and cell regulation.

1979 • 32 citations

Evidence that the rate of phosphatidylcholine catabolism is regulated in cultured rat hepatocytes

1991 • 27 citations

Characterization of volume-sensitive organic osmolyte efflux and anion current in Xenopus oocytes

1997 • 25 citations

Osmotic cell swelling-induced ATP release mediates the activationof extracellular signal-regulated protein kinase (Erk)-1/2 but not the activation of osmo-sensitive anion channels

1999 • 19 citations

Analysis of the gene structure of the human (SLC22A3) and murine (Slc22a3) extraneuronal monoamine transporter

2000 • 17 citations

Voltage-dependent chloride channels: Invertebrates to man

1996 • 15 citations

Identification of the Volume-Sensitive Organic Osmolyte/Anion Channel in Human Glial Cells

1997 • 13 citations

Effects of calcium, calmodulin, protein kinase C and protein tyrosine kinases on volume‐activated taurine efflux in human erythroleukemia cells

2001 • 12 citations