Colocalization of ATP Release Sites and Ecto-ATPase Activity at the Extracellular Surface of Human Astrocytes

Receptors for Purines and Pyrimidines

2012 • 4,065 citations

Molecular Physiology of P2X Receptors

2002 • 2,845 citations

Structure and Function of Sphingolipid- and Cholesterol-rich Membrane Rafts

2000 • 2,321 citations

Proteinase-activated Receptors

2006 • 1,166 citations

Extracellular metabolism of ATP and other nucleotides

2000 • 973 citations

Molecular mechanisms of platelet activation.

1989 • 903 citations

Intercellular Calcium Signaling in Astrocytes via ATP Release through Connexin Hemichannels

2002 • 836 citations

Connexins regulate calcium signaling by controlling ATP release

1998 • 767 citations

Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster

2002 • 715 citations

Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation

1999 • 554 citations

Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture

2001 • 530 citations

Absence of the P2X7 Receptor Alters Leukocyte Function and Attenuates an Inflammatory Response

2002 • 492 citations

Storage and Release of ATP from Astrocytes in Culture

2003 • 489 citations

Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice

1999 • 422 citations

Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family

2003 • 412 citations

Reduced vas deferens contraction and male infertility in mice lacking P2X1 receptors

2000 • 391 citations

TRANSPORTERS OF NUCLEOTIDE SUGARS, ATP, AND NUCLEOTIDE SULFATE IN THE ENDOPLASMIC RETICULUM AND GOLGI APPARATUS

1998 • 377 citations

The cystic fibrosis transmembrane conductance regulator is a dual ATP and chloride channel.

1994 • 354 citations

Pharmacological characterization of recombinant human and rat P2X receptor subtypes

1999 • 328 citations

Properties and regulation of gap junctional hemichannels in the plasma membranes of cultured cells.

1996 • 327 citations

Intercellular calcium signaling mediated by point-source burst release of ATP

2002 • 316 citations

Constitutive Release of ATP and Evidence for Major Contribution of Ecto-nucleotide Pyrophosphatase and Nucleoside Diphosphokinase to Extracellular Nucleotide Concentrations

2000 • 313 citations

Detection of local ATP release from activated platelets using cell surface-attached firefly luciferase

1999 • 300 citations

Direct Demonstration of Mechanically Induced Release of Cellular UTP and Its Implication for Uridine Nucleotide Receptor Activation

1997 • 286 citations

Nucleotide Pyrophosphatases/Phosphodiesterases on the Move

2000 • 283 citations

Response of Schwann Cells to Action Potentials in Development

2000 • 267 citations

Evidence That Release of Adenosine Triphosphate From Endothelial Cells During Increased Shear Stress Is Vesicular

2001 • 264 citations

Bioluminescence detection of ATP release mechanisms in epithelia

1998 • 242 citations

Involvement of astrocytes in purine‐mediated reparative processes in the brain

2001 • 234 citations

Volume-Dependent Atp-Conductive Large-Conductance Anion Channel as a Pathway for Swelling-Induced Atp Release

2001 • 212 citations

Two novel families of ectonucleotidases: molecular structures, catalytic properties and a search for function

1999 • 203 citations

Cystic Fibrosis Transmembrane Conductance Regulator Facilitates ATP Release by Stimulating a Separate ATP Release Channel for Autocrine Control of Cell Volume Regulation

2001 • 195 citations

Intercellular Communication in Spinal Cord Astrocytes: Fine Tuning between Gap Junctions and P2 Nucleotide Receptors in Calcium Wave Propagation

2000 • 192 citations

Cellular Release of and Response to ATP as Key Determinants of the Set-Point of Signal Transduction Pathways

2000 • 190 citations

Effect of Loss of P2Y2 Receptor Gene Expression on Nucleotide Regulation of Murine Epithelial Cl−Transport

1999 • 183 citations

Ecto 5′-Nucleotidase and Nonspecific Alkaline Phosphatase

2003 • 177 citations

Activation of inositol phospholipid breakdown in HL60 cells by P2-purinergic receptors for extracellular ATP. Evidence for mediation by both pertussis toxin-sensitive and pertussis toxin-insensitive mechanisms.

1988 • 166 citations

Photoliberating inositol-1,4,5-trisphosphate triggers ATP release that is blocked by the connexin mimetic peptide gap 26

2003 • 154 citations

A plethora of presynaptic proteins associated with ATP-storing organelles in cultured astrocytes

1999 • 154 citations

Volume-regulated Anion Channels Serve as an Auto/Paracrine Nucleotide Release Pathway in Aortic Endothelial Cells

2002 • 152 citations

The evidence for two opposite, ATP-generating and ATP-consuming, extracellular pathways on endothelial and lymphoid cells

2002 • 151 citations

Extracellular ATP signaling and P2X nucleotide receptors in monolayers of primary human vascular endothelial cells

2002 • 144 citations

ABC transporter-facilitated ATP conductive transport

1999 • 139 citations

Primary structure of rat liver 5'-nucleotidase deduced from the cDNA. Presence of the COOH-terminal hydrophobic domain for possible post-translational modification by glycophospholipid.

1990 • 134 citations

Swelling-Induced, Cftr-Independent Atp Release from a Human Epithelial Cell Line

1999 • 130 citations

Activated Cardiac Adenosine A1 Receptors Translocate Out of Caveolae

2000 • 120 citations

Brefeldin A Block of Integrin-dependent Mechanosensitive ATP Release from Xenopus Oocytes Reveals a Novel Mechanism of Mechanotransduction

2001 • 116 citations

An Ecto‐Nucleotide Pyrophosphatase Is One of the Main Enzymes Involved in the Extracellular Metabolism of ATP in Rat C6 Glioma

1999 • 105 citations

Involvement of Rho‐kinase and tyrosine kinase in hypotonic stress‐induced ATP release in bovine aortic endothelial cells

2001 • 102 citations

A study of the mechanism of the release of ATP from rat cortical astroglial cells evoked by activation of glutamate receptors

1999 • 101 citations

Palmitoylation Targets CD39/Endothelial ATP Diphosphohydrolase to Caveolae

2000 • 90 citations

Swelling‐activated, cystic fibrosis transmembrane conductance regulator‐augmented ATP release and Cl⁻ conductances in murine C127 cells

2000 • 88 citations

Loss of Nucleotide Regulation of Epithelial Chloride Transport in the Jejunum of P2Y₄-Null Mice

2003 • 88 citations

Requirement for Rho-mediated Myosin Light Chain Phosphorylation in Thrombin-stimulated Cell Rounding and Its Dissociation from Mitogenesis

1998 • 84 citations

The Lipid Products of Phosphoinositide 3-Kinase Contribute to Regulation of Cholangiocyte ATP and Chloride Transport

1999 • 79 citations

Anion inhibition of firefly luciferase

1970 • 77 citations

Coupling of the thrombin receptor to G12 may account for selective effects of thrombin on gene expression and DNA synthesis in 1321N1 astrocytoma cells.

1996 • 76 citations

Changes in P2X receptor responses of sensory neurons from P2X₃‐deficient mice

2001 • 71 citations

Real‐time measurements of acetylcholine‐induced release of ATP from bovine medullary chromaffin cells

1985 • 67 citations

Evidence supporting the Nucleotide Axis Hypothesis: ATP release and metabolism by coronary endothelium

2001 • 63 citations

Endotoxin Activation of Macrophages Does Not Induce ATP Release and Autocrine Stimulation of P2 Nucleotide Receptors

2000 • 53 citations

CD39 as a Caveolar-Associated Ectonucleotidase

1999 • 48 citations

Functional Compartmentation of Endothelial P2Y Receptor Signaling

2002 • 44 citations

Release of ATP induced by hypertonic solutions in Xenopus oocytes

2003 • 33 citations

Release of ATP induced by hypertonic solutions in Xenopus oocytes

2002 • 28 citations

β,γ‐Methylene ATP‐induced cAMP formation in C6Bu‐1 cells: involvement of local metabolism and subsequent stimulation of adenosine A_2B receptor

2001 • 26 citations

Adenine Nucleotide-Induced Activation of Adenosine A_2BReceptors Expressed inXenopus laevisOocytes: Involvement of a Rapid and Localized Adenosine Formation by Ectonucleotidases

2002 • 22 citations

Release of Dopamine and ATP from PC12 Cells Treated with Dexamethasone, Reserpine and Bafilomycin A1.

2001 • 19 citations

ATP Compartmentation in Neuroendocrine Secretory Vesicles

1990 • 19 citations