Differential dependence of regulatory volume decrease behavior in rabbit corneal epithelial cells on MAPK superfamily activation

An SV40-immortalized human corneal epithelial cell line and its characterization.

1995 • 714 citations

Cell volume regulation: osmolytes, osmolyte transport, and signal transduction

2003 • 362 citations

p38 and ERK1/2 Coordinate Cellular Migration and Proliferation in Epithelial Wound Healing

2003 • 333 citations

Ion Channels in Cell Proliferation and Apoptotic Cell Death

2005 • 322 citations

Modulation of Glioma Cell Migration and Invasion Using Cl⁻and K⁺Ion Channel Blockers

1999 • 295 citations

Tetracycline Repressor, tetR, rather than the tetR–Mammalian Cell Transcription Factor Fusion Derivatives, Regulates Inducible Gene Expression in Mammalian Cells

1998 • 250 citations

Fluid shear stress inhibits TNF-α activation of JNK but not ERK1/2 or p38 in human umbilical vein endothelial cells: Inhibitory crosstalk among MAPK family members

2001 • 224 citations

Dual MAP kinase pathways mediate opposing forms of long-term plasticity at CA3–CA1 synapses

2000 • 223 citations

Ca2+ sensitivity of volume‐regulatory K+ and Cl‐ channels in cultured human epithelial cells.

1988 • 223 citations

K-Cl Cotransport: Properties and Molecular Mechanism

2000 • 215 citations

Volume‐regulatory Cl‐ channel currents in cultured human epithelial cells.

1992 • 185 citations

Mitogen-Activated Protein and Tyrosine Kinases in the Activation of Astrocyte Volume-Activated Chloride Current

1998 • 166 citations

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2002 • 166 citations

Volume-activated Cl− channels

1996 • 163 citations

Stress-induced Inhibition of ERK1 and ERK2 by Direct Interaction with p38 MAP Kinase

2001 • 163 citations

Site and mode of adrenaline action on chloride transport across the rabbit corneal epithelium.

1977 • 163 citations

Tyrosine kinase activation is an immediate and essential step in hypotonic cell swelling-induced ERK activation and c-fos gene expression in cardiac myocytes.

1996 • 152 citations

Cell swelling activates K+ and Cl? channels as well as nonselective, stretch-activated cation channels in ehrlich ascites tumor cells

1992 • 145 citations

The role of MAP kinases in endothelial activation

2002 • 140 citations

p38 Kinase Is a Negative Regulator of Angiotensin II Signal Transduction in Vascular Smooth Muscle Cells

1998 • 131 citations

Activation of extracellular signal-regulated kinases Erk-1 and Erk-2 by cell swelling in H4IIE hepatoma cells

1995 • 129 citations

Ca2+ Signaling, Intracellular pH and Cell Volume in Cell Proliferation

2005 • 125 citations

Volume changes in single N1E-115 neuroblastoma cells measured with a fluorescent probe

1995 • 122 citations

Relative contribution of chloride channels and transporters to regulatory volume decrease in human glioma cells

2005 • 112 citations

Inhibition of p38 MAP Kinase Activity Up-Regulates Multiple MAP Kinase Pathways and Potentiates 1,25-Dihydroxyvitamin D3-Induced Differentiation of Human Leukemia HL60 Cells

2000 • 105 citations

Calcium-dependent activation of Erk-1 and Erk-2 after hypo-osmotic astrocyte swelling

1996 • 104 citations

Hypo‐osmotic cell swelling activates the p38 MAP kinase signalling cascade

1996 • 88 citations

Phosphatase-Mediated Crosstalk Control of ERK and p38 MAPK Signaling in Corneal Epithelial Cells

2006 • 84 citations

Cell Shrinkage Triggers the Activation of Mitogen-activated Protein Kinases by Hypertonicity in the Rat Kidney Medullary Thick Ascending Limb of the Henle's Loop

1999 • 79 citations

Volume‐sensitive chloride channels in mouse cortical neurons: characterization and role in volume regulation

2005 • 68 citations

Sequential Activation of ERK and Repression of JNK by Scatter Factor/Hepatocyte Growth Factor in Madin-Darby Canine Kidney Epithelial Cells

2000 • 65 citations

Volume-sensitive KCl cotransport associated with human cervical carcinogenesis

2000 • 63 citations

Osmotic regulation of the heat shock response in primary rat hepatocytes

1998 • 58 citations

Cell Swelling Activates Stress-Activated Protein Kinases, p38 MAP Kinase and JNK, in Renal Epithelial A6 Cells

1999 • 58 citations

Human cervical cancer cells use Ca²⁺ signalling, protein tyrosine phosphorylation and MAP kinase in regulatory volume decrease

2001 • 55 citations

Regulatory Volume Decrease by SV40-transformed Rabbit Corneal Epithelial Cells Requires Ryanodine-sensitive Ca 2+ -induced Ca 2+ Release

1997 • 53 citations

Regulation of cloned, Ca2+-activated K+ channels by cell volume changes

2002 • 52 citations

Regulatory volume increase is associated with p38 kinase-dependent actin cytoskeleton remodeling in rat kidney MTAL

2003 • 52 citations

The Mitogen-Activated Protein Kinase p38-2 Is Necessary for the Inhibition of N-Type Calcium Current by Bradykinin

1998 • 49 citations

Osmotic stress, a proinflammatory signal in Caco-2 cells

2004 • 47 citations

Regulation of Hormone Secretion by Acute Cell Volume Changes: Ca<sup>2+</sup>-Independent Hormone Secretion

2000 • 47 citations

Characterization of Regulatory Volume Behavior by Fluorescence Quenching in Human Corneal Epithelial Cells

2005 • 43 citations

Role of p38<sup>MAPK</sup> in Cell Volume Regulation of Perfused Rat Liver

2001 • 42 citations

Hypoosmotic Stress Activates p38, ERK 1 and 2, and SAPK/JNK in Rat Hepatocytes

2000 • 40 citations

Involvement of regulatory volume decrease in the migration of nasopharyngeal carcinoma cells

2005 • 39 citations

Hypertonicity-induced p38MAPK Activation Elicits Recovery of Corneal Epithelial Cell Volume and Layer Integrity

2003 • 38 citations

Adaptation by Corneal Epithelial Cells to Chronic Hypertonic Stress Depends on Upregulation of Na:K:2Cl Cotransporter Gene and Protein Expression and Ion Transport Activity

2000 • 36 citations

Single calcium-activated potassium channel in cultured mammary epithelial cells

1989 • 34 citations

Control of SV-40 transformed RCE cell proliferation by growth-factor-induced cell cycle progression

2001 • 29 citations

Fate of hypertonicity-stressed corneal epithelial cells depends on differential MAPK activation and p38MAPK/Na–K–2Cl cotransporter1 interaction

2006 • 25 citations

Swelling-Activated Cl⁻Channels Support Cl⁻Secretion by Bovine Ciliary Epithelium

2006 • 25 citations

Activation of extracellular signal-regulated kinase ERK after hypo-osmotic stress in renal epithelial A6 cells

2004 • 21 citations

Functional and Molecular Characterization of a Volume-activated Chloride Channel in Rabbit Corneal Epithelial Cells

2004 • 21 citations

Cardiac Swelling-Induced Chloride Current is Enhanced by Endothelin

2000 • 19 citations

p38MAPK Inhibition Enhances Basal and Norepinephrine-Stimulated p42/44MAPK Phosphorylation in Rat Pinealocytes**This work was supported by grants from the Medical Research Council of Canada.

2000 • 18 citations

Functional and molecular characterization of multiple K–Cl cotransporter isoforms in corneal epithelial cells

2007 • 13 citations

Reduction of water permeability by anisotonic solutions in frog corneal epithelium.

1998 • 9 citations

Swelling of rat mesangial cells induces a Ca2+-dependent Cl− conductance

1996 • 8 citations

p38MAPK Inhibition Enhances Basal and Norepinephrine-Stimulated p42/44MAPK Phosphorylation in Rat Pinealocytes

2000 • 6 citations

Volume-sensitive Cl− Current in Bovine Adrenocortical Cells: Comparison with the ACTH-induced Cl− Current

2004 • 2 citations