ATP regulates anion channel-mediated organic osmolyte release from cultured rat astrocytes via multiple Ca²⁺-sensitive mechanisms

Receptors for Purines and Pyrimidines

2012 • 4,065 citations

Functional Significance of Cell Volume Regulatory Mechanisms

1998 • 1,871 citations

Glutamate-mediated astrocyte–neuron signalling

1994 • 1,688 citations

Glia: listening and talking to the synapse

2001 • 1,401 citations

Functional Hemichannels in Astrocytes: A Novel Mechanism of Glutamate Release

2003 • 697 citations

Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures

1990 • 689 citations

Volume expansion-sensing outward-rectifier Cl- channel: fresh start to the molecular identity and volume sensor

1997 • 652 citations

Cellular and molecular physiology of volume-sensitive anion channels

1996 • 620 citations

Receptor‐mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD)

2001 • 523 citations

P2X₇Receptor-Mediated Release of Excitatory Amino Acids from Astrocytes

2003 • 479 citations

Properties of volume-regulated anion channels in mammalian cells

1997 • 357 citations

Volume-sensitive anion channels mediate swelling-activated inositol and taurine efflux

1993 • 331 citations

Autocrine signaling through ATP release represents a novel mechanism for cell volume regulation.

1996 • 328 citations

Cytosolic calcium oscillations in astrocytes may regulate exocytotic release of glutamate.

2001 • 283 citations

Cytosolic Calcium Oscillations in Astrocytes May Regulate Exocytotic Release of Glutamate

2001 • 264 citations

Reciprocal communication systems between astrocytes and neurones

2000 • 236 citations

Agonist action of taurine on glycine receptors in rat supraoptic magnocellular neurones: possible role in osmoregulation

1997 • 214 citations

Protein tyrosine phosphorylation is involved in osmoregulation of ionic conductances.

1993 • 211 citations

Inhibition of Ischemia-Induced Glutamate Release in Rat Striatum by Dihydrokinate and an Anion Channel Blocker

1999 • 202 citations

ATP Released From Astrocytes During Swelling Activates Chloride Channels

2003 • 195 citations

Osmotic regulation of neuronal activity: a new role for taurine and glial cells in a hypothalamic neuroendocrine structure

2000 • 193 citations

Dissociation of neonatal rat brain by dispase for preparation of primary astrocyte cultures

1984 • 174 citations

Anion channels for amino acids in MDCK cells

1992 • 172 citations

Mitogen-Activated Protein and Tyrosine Kinases in the Activation of Astrocyte Volume-Activated Chloride Current

1998 • 166 citations

The volume-sensitive organic osmolyte-anion channel VSOAC is regulated by nonhydrolytic ATP binding

1994 • 156 citations

Swelling-Induced, Cftr-Independent Atp Release from a Human Epithelial Cell Line

1999 • 130 citations

Properties and glial origin of osmotic‐dependent release of taurine from the rat supraoptic nucleus

1998 • 130 citations

Mechanisms of cell volume regulation and possible nature of the cell volume sensor

2001 • 116 citations

ATP potently modulates anion channel-mediated excitatory amino acid release from cultured astrocytes

2002 • 116 citations

Release of [³H]-d-Aspartate from Primary Astrocyte Cultures in Response to Raised External Potassium

1996 • 112 citations

Osmoregulation of Vasopressin Secretion via Activation of Neurohypophysial Nerve Terminals Glycine Receptors by Glial Taurine

2001 • 112 citations

Cell swelling activates separate taurine and chloride channels in Ehrlich mouse ascites tumor cells

1994 • 111 citations

Acute treatment with tamoxifen reduces ischemic damage following middle cerebral artery occlusion

2000 • 109 citations

Pharmacological characterization of swelling-induced<scp>d</scp>-[³H]aspartate release from primary astrocyte cultures

1998 • 106 citations

Inhibition by anion channel blockers of ischemia-evoked release of excitotoxic and other amino acids from rat cerebral cortex

1997 • 105 citations

Calcium-dependent activation of Erk-1 and Erk-2 after hypo-osmotic astrocyte swelling

1996 • 104 citations

Cellular Function and Control of Volume-Regulated Anion Channels

2001 • 103 citations

FUNCTIONAL PROPERTIES AND PHYSIOLOGICAL ROLES OF ORGANIC SOLUTE CHANNELS

1998 • 99 citations

Membrane Capacitance of Cortical Neurons and Glia During Sleep Oscillations and Spike-Wave Seizures

1999 • 89 citations

Rho family GTP binding proteins are involved in the regulatory volume decrease process in NIH3T3 mouse fibroblasts

2002 • 79 citations

Amino acid current through anion channels in cultured human glial cells

1995 • 78 citations

Phloretin differentially inhibits volume‐sensitive and cyclic AMP‐activated, but not Ca‐activated, Cl⁻ channels

2001 • 78 citations

PKC-δ and CaMKII-δ₂ mediate ATP-dependent activation of ERK1/2 in vascular smooth muscle

2004 • 72 citations

Alteration in Fatty Acid Composition of Adult Rat Brain Capillaries and Choroid Plexus Induced by a Diet Deficient in n‐3 Fatty Acids: Slow Recovery After Substitution with a Nondeficient Diet

1988 • 69 citations

Volume-sensitive chloride current in pigmented ciliary epithelial cells: role of phospholipases

1997 • 65 citations

Volume-dependent taurine release from cultured astrocytes requires permissive [Ca²⁺]_iand calmodulin

1999 • 63 citations

[³H]taurine and<scp>d</scp>-[³H]aspartate release from astrocyte cultures are differently regulated by tyrosine kinases

1999 • 62 citations

Activation of the volume-sensitive chloride current in vascular endothelial cells requires a permissive intracellular Ca2+ concentration

1996 • 60 citations

Three different Cl‐ channels in the bovine ciliary epithelium activated by hypotonic stress.

1997 • 58 citations

Osmotic cell swelling-induced ATP release mediates the activationof extracellular signal-regulated protein kinase (Erk)-1/2 but not the activation of osmo-sensitive anion channels

1999 • 58 citations

Role of cell volume and protein kinase C in regulation of a Cl‐ conductance in single proximal tubule cells of Rana temporaria.

1994 • 57 citations

Activation of protein kinase C? couples cell volume to membrane Cl? permeability in HTC hepatoma and Mz-ChA-1 cholangiocarcinoma cells

1998 • 56 citations

Tyrosine phosphorylation modulates the osmosensitivity of volume‐dependent taurine efflux from glial cells in the rat supraoptic nucleus

2000 • 56 citations

Organic Osmolyte Channels: A Comparative View

2000 • 49 citations

Activation of NMDA receptors is necessary for the induction of associative long‐term potentiation in area CA1 of the rat hippocampal slice

1997 • 48 citations

Expression and translocation of protein kinase C isoforms in rat microglial and astroglial cultures

1999 • 47 citations

Binding inhibition of angiogenic factors by heparan sulfate proteoglycans in aqueous humor: potential mechanism for maintenance of an avascular environment

2003 • 47 citations

Activation of the volume-sensitive chloride current in vascular endothelial cells requires a permissive intracellular Ca

1996 • 46 citations

The Role of P2Y1 Purinergic Receptors and Cytosolic Ca2+ in Hypotonically Activated Osmolyte Efflux from a Rat Hepatoma Cell Line

2002 • 45 citations

Vasopressin‐induced taurine efflux from rat pituicytes: a potential negative feedback for hormone secretion

2003 • 42 citations

Osmotic Swelling‐Induced Changes in Cytosolic Calcium Do Not Affect Regulatory Volume Decrease in Rat Cultured Suspended Cerebellar Astrocytes

1998 • 41 citations

Myosin light chain phosphorylation‐dependent modulation of volume‐regulated anion channels in macrovascular endothelium

2000 • 41 citations

Phospholipase C, Protein Kinase C, Ca²⁺/Calmodulin‐Dependent Protein Kinase II, and Tyrosine Phosphorylation Are Involved in Carbachol‐Induced Phospholipase D Activation in Chinese Hamster Ovary Cells Expressing Muscarinic Acetylcholine Receptor of Caenorhabditis elegans

2000 • 39 citations

Peroxynitrite enhances astrocytic volume‐sensitive excitatory amino acid release via a src tyrosine kinase‐dependent mechanism

2002 • 39 citations

Calcium/calmodulin-modulated chloride and taurine conductances in cultured rat astrocytes

2002 • 37 citations

Activation of muscarinic cholinergic receptors enhances the volume‐sensitive efflux of myo‐inositol from SH‐SY5Y neuroblastoma cells

2003 • 37 citations

Potentiation of the osmosensitive taurine release and cell volume regulation by cytosolic Ca²⁺ rise in cultured cerebellar astrocytes

2003 • 36 citations

Protein kinase C-independent correlation between P-glycoprotein expression and volume sensitivity of Cl− channel

1997 • 36 citations

Inhibition of Release of Taurine and Excitatory Amino Acids in Ischemia and Neuroprotection

2003 • 35 citations

Astrocytic Swelling in Neuropathology

2004 • 34 citations

Purinergic-independent Calcium Signaling Mediates Recovery from Hepatocellular Swelling

2001 • 34 citations

Intracellular ATP depletion inhibits swelling-induced d-[3H]aspartate release from primary astrocyte cultures

1999 • 32 citations

Regulation of volume-sensitive outwardly rectifying anion channels in pulmonary arterial smooth muscle cells by PKC

2002 • 32 citations

Increases in Intracellular pH and Ca 2+ are Essential for K + Channel Activation After Modest `Physiological' Swelling in Villus Epithelial Cells

1999 • 31 citations

Myosin light chain kinase is expressed in neurons and glia: immunoblotiing and immunocytochemical studies

1992 • 28 citations

Calmodulin Kinase II in Pure Cultured Astrocytes

1988 • 27 citations

Ca 2+ /Calmodulin Kinase II and Decreases in Intracellular pH are Required to Activate K + Channels After Substantial Swelling in Villus Epithelial Cells

1999 • 27 citations

Calmodulin Is a Phospholipase C-β Interacting Protein

2003 • 25 citations

Modulation of delayed rectifier potassium current by angiotensin II in CATH.a cells

2003 • 22 citations

Osmotic cell swelling-induced ATP release mediates the activationof extracellular signal-regulated protein kinase (Erk)-1/2 but not the activation of osmo-sensitive anion channels

1999 • 19 citations

Heterogeneity of Volume-sensitive Chloride Channels in Basolateral Membranes of A6 Epithelial Cells in Culture

1996 • 17 citations

Volume‐regulated anion conductance in cultured rat cerebral astrocytes requires calmodulin activity

2004 • 13 citations

Ca2+/Calmodulin Inhibition and Phospholipase C-Linked Ca2+ Signaling in Clonalβ -Cells1

1999 • 11 citations

Ca2+/Calmodulin Inhibition and Phospholipase C-Linked Ca2+ Signaling in Clonal -Cells

1999 • 3 citations