Ca2+-mediated Potentiation of the Swelling-induced Taurine Efflux from HeLa Cells: On the Role of Calmodulin and Novel Protein Kinase C Isoforms

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

2012 • 8,865 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Functional Significance of Cell Volume Regulatory Mechanisms

1998 • 1,871 citations

The extended protein kinase C superfamily

1998 • 1,544 citations

International Union of Pharmacology. XIII. Classification of histamine receptors.

1997 • 869 citations

Volume expansion-sensing outward-rectifier Cl- channel: fresh start to the molecular identity and volume sensor

1997 • 652 citations

Cellular and molecular physiology of volume-sensitive anion channels

1996 • 620 citations

Generation of cAMP-Activated Chloride Currents by Expression of CFTR

1991 • 550 citations

Membrane Mechanisms and Intracellular Signalling in Cell Volume Regulation

1995 • 469 citations

Properties of volume-regulated anion channels in mammalian cells

1997 • 357 citations

Calcium signaling in cell volume regulation

1992 • 349 citations

Calmodulin as an Ion Channel Subunit

2002 • 336 citations

The Diversity of Volume Regulatory Mechanisms

1998 • 310 citations

Cell Volume in the Regulation of Cell Proliferation and Apoptotic Cell Death

2000 • 251 citations

Protein kinase D: an intracellular traffic regulator on the move

2002 • 221 citations

Volume-induced increase of K+ and Cl− permeabilities in Ehrlich ascites tumor cells. Role of internal Ca2+

1984 • 211 citations

Protein kinase C-mediated phosphorylation of the human multidrug resistance P-glycoprotein regulates cell volume-activated chloride channels.

1995 • 191 citations

Regulation of the Cellular Content of the Organic Osmolyte Taurine in Mammalian Cells

2003 • 190 citations

Anion channels for amino acids in MDCK cells

1992 • 172 citations

Critical Duration of Intracellular Ca2+ Response Required for Continuous Translocation and Activation of Cytosolic Phospholipase A2

1999 • 172 citations

Anion Permeation in Ca2+-Activated Cl− Channels

2000 • 163 citations

Molecular Basis of the Specific Subcellular Localization of the C2-like Domain of 5-Lipoxygenase

2002 • 162 citations

The Tyrosine Kinase p56lck Mediates Activation of Swelling-induced Chloride Channels in Lymphocytes

1998 • 161 citations

Calcium/Calmodulin-dependent Protein Kinase IIα Mediates Activation of Mitogen-activated Protein Kinase and Cytosolic Phospholipase A2 in Norepinephrine-induced Arachidonic Acid Release in Rabbit Aortic Smooth Muscle Cells

1996 • 154 citations

Activation of extracellular signal-regulated kinases Erk-1 and Erk-2 by cell swelling in H4IIE hepatoma cells

1995 • 129 citations

Cell swelling activates separate taurine and chloride channels in Ehrlich mouse ascites tumor cells

1994 • 111 citations

Guinea Pig Histamine H₁ Receptor. II. Stable Expression in Chinese Hamster Ovary Cells Reveals the Interaction with Three Major Signal Transduction Pathways

1994 • 110 citations

Regulatory volume decrease in cultured astrocytes. I. Potassium- and chloride-activated permeability

1994 • 103 citations

Ion permeation and selectivity in ClC-type chloride channels

2001 • 103 citations

Cellular Function and Control of Volume-Regulated Anion Channels

2001 • 103 citations

Separate taurine and chloride efflux pathways activated during regulatory volume decrease

1999 • 97 citations

The Ca2+-sensing Receptor Activates Cytosolic Phospholipase A2 via a Gqα-dependent ERK-independent Pathway

2001 • 96 citations

Mechanism and regulation of swelling-activated inositol efflux in brain glial cells

1993 • 95 citations

Regulation of taurine transport in Ehrlich ascites tumor cells

1993 • 94 citations

Volume regulation in NIH/3T3 cells not expressing P-glycoprotein. II. Chloride and amino acid fluxes

1997 • 94 citations

Anion selectivity of apical membrane conductance of Calu 3 human airway epithelium

1999 • 93 citations

Influence of Calcium on Regulatory Volume Decrease: Role of Potassium Channels

2000 • 92 citations

Identification of the Calmodulin-binding Domain of Recombinant Calcium-independent Phospholipase A2β

2001 • 92 citations

Dynamic regulation of [Ca2+]iby plasma membrane Ca2+-ATPase and Na+/Ca2+exchange during capacitative Ca2+entry in bovine vascular endothelial cells

1999 • 88 citations

Swelling-activated anion conductance in skate hepatocytes: regulation by cell Cl- and ATP

1996 • 84 citations

Regulatory Volume Decrease and Intracellular Ca2+ in Murine Neuroblastoma Cells Studied with Fluorescent Probes

1998 • 84 citations

Inhibition of Jurkat-T-lymphocyte Na+/H+-exchanger by CD95(Fas/Apo-1)-receptor stimulation

2000 • 84 citations

Reactive oxygen species are important mediators of taurine release from skeletal muscle cells

2003 • 83 citations

Effects of Cl channel blockers on Ca‐activated chloride and potassium currents in smooth muscle cells from rabbit portal vein

1994 • 79 citations

Swelling-Induced Arachidonic Acid Release via the 85-kDa cPLA₂in Human Neuroblastoma Cells

1998 • 79 citations

Rho family GTP binding proteins are involved in the regulatory volume decrease process in NIH3T3 mouse fibroblasts

2002 • 79 citations

Amino acid current through anion channels in cultured human glial cells

1995 • 78 citations

Reactive Oxygen Species Regulate Swelling-induced Taurine Efflux in NIH3T3 Mouse Fibroblasts

2003 • 77 citations

Volume‐regulatory taurine release from a human lung cancer cell line

1993 • 75 citations

Inhibition of volume-activated I- and taurine efflux from HeLa cells by P-glycoprotein blockers correlates with calmodulin inhibition.

1994 • 71 citations

On the Role of Calcium in the Regulatory Volume Decrease (RVD) Response in Ehrlich Mouse Ascites Tumor Cells

1997 • 70 citations

Short‐term desensitization of the histamine H₁ receptor in human HeLa cells: involvement of protein kinase C dependent and independent pathways

1992 • 67 citations

Anion channel blockers inhibit swelling-activated anion, cation, and nonelectrolyte transport in HeLa cells

1996 • 65 citations

[³H]taurine and<scp>d</scp>-[³H]aspartate release from astrocyte cultures are differently regulated by tyrosine kinases

1999 • 62 citations

Pharmacological characterization of volume‐sensitive, taurine permeable anion channels in rat supraoptic glial cells

2000 • 61 citations

Activation of the volume-sensitive chloride current in vascular endothelial cells requires a permissive intracellular Ca2+ concentration

1996 • 60 citations

Characterization of the Increase in [Ca2+] i During Hypotonic Shock and the Involvement of Ca2+-activated K+ Channels in the Regulatory Volume Decrease in Human Osteoblast-like Cells

2000 • 56 citations

Tyrosine phosphorylation modulates the osmosensitivity of volume‐dependent taurine efflux from glial cells in the rat supraoptic nucleus

2000 • 56 citations

Human cervical cancer cells use Ca²⁺ signalling, protein tyrosine phosphorylation and MAP kinase in regulatory volume decrease

2001 • 55 citations

The involvement of caspases in the CD95(Fas/Apo-1)- but not swelling-induced cellular taurine release from Jurkat T-lymphocytes

2000 • 55 citations

A swelling‐activated chloride current in rat sympathetic neurones

1997 • 54 citations

Serotonin uptake inhibitors modulate intracellular Ca2+ mobilization in platelets

1995 • 54 citations

Ca2+ oscillations induced by histamine H1 receptor stimulation in HeLa cells: Fura-2 and patch clamp analysis

1991 • 50 citations

Isosmotic modulation of cell volume and intracellular ion activities during stimulation of single exocrine cells

1994 • 47 citations

Modulation by extracellular Cl- of volume-activated organic osmolyte and halide permeabilities in HeLa cells

1997 • 46 citations

Regulatory volume decrease and associated osmolyte fluxes in cerebellar granule neurons are calcium independent

1997 • 46 citations

Activation of the volume-sensitive chloride current in vascular endothelial cells requires a permissive intracellular Ca

1996 • 46 citations

The Role of P2Y1 Purinergic Receptors and Cytosolic Ca2+ in Hypotonically Activated Osmolyte Efflux from a Rat Hepatoma Cell Line

2002 • 45 citations

Osmotic Swelling‐Induced Changes in Cytosolic Calcium Do Not Affect Regulatory Volume Decrease in Rat Cultured Suspended Cerebellar Astrocytes

1998 • 41 citations

Effect of osmolality and anion channel inhibitors on myo-inositol efflux in cultured astrocytes

1999 • 38 citations

Involvement of PKC‐α in regulatory volume decrease responses and activation of volume‐sensitive chloride channels in human cervical cancer HT‐3 cells

1998 • 37 citations

Tyrosine Kinases Open Lymphocyte Chloride Channels

2000 • 37 citations

Studies on Human Porin XXII: Cell Membrane Integrated Human Porin Channels Are Involved in Regulatory Volume Decrease (RVD) of HeLa Cells

2000 • 36 citations

Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases

1999 • 35 citations

Influence of protein kinases on the osmosensitive release of taurine from cerebellar granule neurons

2001 • 33 citations

Synergetic activation of outwardly rectifying Cl⁻ currents by hypotonic stress and external Ca²⁺ in murine osteoclasts

1999 • 33 citations

Swelling-activated Taurine and Creatine Effluxes from Rat Cortical Astrocytes are Pharmacologically Distinct

2002 • 31 citations

Increases in Intracellular pH and Ca 2+ are Essential for K + Channel Activation After Modest `Physiological' Swelling in Villus Epithelial Cells

1999 • 31 citations

Leukotriene D 4 (LTD 4 ) activates charybdotoxin-sensitive and -insensitive K + channels in Ehrlich ascites tumor cells

1999 • 30 citations

Regulation of the Taurine Content in Ehrlich Ascites Tumour Cells

1998 • 30 citations

Swelling-induced changes in cytosolic [Ca2+] in insulin-secreting cells: a role in regulatory volume decrease?

2001 • 29 citations

Neuronal swelling and surface area regulation: elevated intracellular calcium is not a requirement

1998 • 29 citations

Desensitization of histamine H₁ receptor‐mediated inositol phosphate production in HeLa cells

1993 • 27 citations

Chloride and taurine effluxes occur by different pathways in skate erythrocytes

1996 • 27 citations

Increased Cytosolic Ca2+ Concentration in Endothelial Cells by Calmodulin Antagonists

1999 • 24 citations

Single-channel and Fura-2 analysis of internal Ca2+ oscillations in HeLa cells: contribution of the receptor-evoked Ca2+ influx and effect of internal pH

1990 • 24 citations

Further evidence for the existence of a volume‐activated taurine efflux pathway in rat mammary tissue independent from volume‐sensitive Cl^– channels

2000 • 23 citations

Gadolinium as an opener of the outwardly rectifying Cl - channel (ORCC). Is there relevance for cystic fibrosis therapy?

2001 • 22 citations

Intracellular signalling involved in activation of the volume-sensitive K+ current in Ehrlich ascites tumour cells

2001 • 21 citations

Calcium-induced calcium release participates in cell volume regulation of rabbit TALH cells

2002 • 21 citations

HeLa cells have histamine H1-receptors which mediate activation of the K+ conductance

1985 • 21 citations

Methylmercury-induced inhibition of regulatory volume decrease in astrocytes: characterization of osmoregulator efflux and its reversal by amiloride

1998 • 20 citations

Lysophosphatidylcholine Induces Taurine Release from HeLa Cells

2000 • 20 citations

Cardiac Swelling-Induced Chloride Current is Enhanced by Endothelin

2000 • 19 citations

Volume regulation in NIH/3T3 cells not expressing P-glycoprotein. I. Regulatory volume decrease

1997 • 19 citations

Ca2+ mobilization induced by W-7 in MG63 human osteosarcoma cells

2000 • 18 citations

Swelling-Induced Taurine Efflus from Hela Cells: Cell Volume Regulation

2002 • 17 citations

Properties of Volume-activated Taurine and Iodide Efflux from Term Human Placental Tissue

1999 • 13 citations

Protein Kinase C and Regulatory Volume Decrease in Mudpuppy Red Blood Cells

1998 • 12 citations

The Calmodulin Antagonist W-7 Depletes Intracellular Calcium Stores in FRTL-5 Thyroid Cells

1993 • 10 citations

Regulatory changes in the K+, Cl− and water contents of HeLa cells incubated in an isosmotic high K+-medium

1991 • 9 citations

The effect of N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) on muscarinic receptor-induced Ca2+ mobilization in a human salivary epithelial cell line

1990 • 9 citations

Calcium Modulates Osmosensitive Taurine Efflux in HeLa Cells

2003 • 8 citations

The Role of Calcium in the Control of Volume-Regulatory Transport Pathways

2020 • 5 citations

Histamine-stimulated Cl- transport in HeLa cells

1995 • 1 citations