SPECIFICITY AND VERSATILITY IN TGF-β SIGNALING THROUGH SMADS

Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus

2003 • 5,611 citations

Smad-dependent and Smad-independent pathways in TGF-β family signalling

2003 • 5,052 citations

Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling

1997 • 1,774 citations

Making sense of latent TGFβ activation

2002 • 1,579 citations

The Two-Handed E Box Binding Zinc Finger Protein SIP1 Downregulates E-Cadherin and Induces Invasion

2001 • 1,351 citations

The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling

1997 • 1,328 citations

Smad7 Binds to Smurf2 to Form an E3 Ubiquitin Ligase that Targets the TGFβ Receptor for Degradation

2000 • 1,299 citations

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

2003 • 1,115 citations

Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors

2002 • 1,088 citations

Smad6 inhibits signalling by the TGF-β superfamily

1997 • 1,026 citations

Integration of Smad and Forkhead Pathways in the Control of Neuroepithelial and Glioblastoma Cell Proliferation

2004 • 1,008 citations

A mechanism of repression of TGFbeta / Smad signaling by oncogenic Ras

1999 • 1,004 citations

SARA, a FYVE Domain Protein that Recruits Smad2 to the TGFβ Receptor

1998 • 952 citations

Human Smad3 and Smad4 Are Sequence-Specific Transcription Activators

1998 • 916 citations

Betaglycan presents ligand to the TGFβ signaling receptor

1993 • 887 citations

Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1

1997 • 867 citations

Identification and Functional Characterization of Distinct Critically Important Bone Morphogenetic Protein-specific Response Elements in the Id1 Promoter

2002 • 849 citations

Smurf1 Interacts with Transforming Growth Factor-β Type I Receptor through Smad7 and Induces Receptor Degradation

2001 • 828 citations

Inhibition of transforming growth factor-β/SMAD signalling by the interferon-γ/STAT pathway

1999 • 800 citations

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcription

1998 • 789 citations

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

1998 • 714 citations

Integration of TGF-β/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition

2004 • 710 citations

Crystal Structure of a Smad MH1 Domain Bound to DNA

1998 • 709 citations

Ras and TGFβ cooperatively regulate epithelial cell plasticity and metastasis

2002 • 693 citations

Myc suppression of the p21Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

2002 • 676 citations

Activin Receptor-like Kinase (ALK)1 Is an Antagonistic Mediator of Lateral TGFβ/ALK5 Signaling

2003 • 657 citations

Endoglin promotes endothelial cell proliferation and TGF-β/ALK1 signal transduction

2004 • 622 citations

Smad4 and FAST-1 in the assembly of activin-responsive factor

1997 • 567 citations

A Self-Enabling TGFβ Response Coupled to Stress Signaling

2003 • 539 citations

Interdependent SMAD and JNK Signaling in Transforming Growth Factor-β-mediated Transcription

1999 • 534 citations

The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for Smad3 in TGF-β-induced transcriptional activation

1998 • 527 citations

Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic

1997 • 524 citations

TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation

2001 • 514 citations

Smad2 and Smad3 Positively and Negatively Regulate TGFβ-Dependent Transcription through the Forkhead DNA-Binding Protein FAST2

1998 • 513 citations

SIP1, a Novel Zinc Finger/Homeodomain Repressor, Interacts with Smad Proteins and Binds to 5′-CACCT Sequences in Candidate Target Genes

1999 • 492 citations

Cyclin-dependent kinases regulate the antiproliferative function of Smads

2004 • 485 citations

TGFβ influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b

2001 • 479 citations

E2F4/5 and p107 as Smad Cofactors Linking the TGFβ Receptor to c-myc Repression

2002 • 475 citations

Specific Activation of Smad1 Signaling Pathways by the BMP7 Type I Receptor, ALK2

1998 • 472 citations

The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling

1999 • 471 citations

Interaction between Wnt and TGF-β signalling pathways during formation of Spemann's organizer

2000 • 467 citations

A structural basis for mutational inactivation of the tumour suppressor Smad4

1997 • 459 citations

A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA.

2000 • 455 citations

Interaction and Functional Cooperation of PEBP2/CBF with Smads

1999 • 449 citations

Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-β and Wnt pathways

2000 • 444 citations

Convergence of Transforming Growth Factor-β and Vitamin D Signaling Pathways on SMAD Transcriptional Coactivators

1999 • 442 citations

Multiple Tumor Suppressor Pathways Negatively Regulate Telomerase

2003 • 433 citations

OAZ Uses Distinct DNA- and Protein-Binding Zinc Fingers in Separate BMP-Smad and Olf Signaling Pathways

2000 • 428 citations

Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction

2003 • 411 citations

A mechanism of suppression of TGF–β/SMAD signaling by NF-κB/RelA

2000 • 397 citations

Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15Ink4B transcription in response to TGF-β

2000 • 392 citations

Role of Smad Proteins and Transcription Factor Sp1 in p21Waf1/Cip1 Regulation by Transforming Growth Factor-β

2000 • 389 citations

Akt interacts directly with Smad3 to regulate the sensitivity to TGF-β-induced apoptosis

2004 • 384 citations

TGF-β inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3

2001 • 383 citations

Differential Roles for Bone Morphogenetic Protein (BMP) Receptor Type IB and IA in Differentiation and Specification of Mesenchymal Precursor Cells to Osteoblast and Adipocyte Lineages

1998 • 379 citations

Nodal Signals to Smads through Cripto-Dependent and Cripto-Independent Mechanisms

2001 • 377 citations

Synergistic Cooperation between Hypoxia and Transforming Growth Factor-β Pathways on Human Vascular Endothelial Growth Factor Gene Expression

2001 • 374 citations

Links between Tumor Suppressors

2003 • 372 citations

PKB/Akt modulates TGF-β signalling through a direct interaction with Smad3

2004 • 369 citations

The oncoprotein Evi-1 represses TGF-β signalling by inhibiting Smad3

1998 • 369 citations

Control of Smad7 Stability by Competition between Acetylation and Ubiquitination

2002 • 366 citations

Determinants of specificity in TGF-β signal transduction

1998 • 364 citations

Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins

2003 • 364 citations

The TGFβ Receptor Activation Process

2001 • 360 citations

Cross-talk between the Notch and TGF-β signaling pathways mediated by interaction of the Notch intracellular domain with Smad3

2003 • 360 citations

ATF-2 Is a Common Nuclear Target of Smad and TAK1 Pathways in Transforming Growth Factor-β Signaling

1999 • 347 citations

Identification of Type I and Type II Serine/Threonine Kinase Receptors for Growth/Differentiation Factor-5

1996 • 336 citations

Repression of Runx2 function by TGF-β through recruitment of class II histone deacetylases by Smad3

2005 • 334 citations

Positive and negative regulation of TGF-β signaling

2000 • 333 citations

A RUNX2/PEBP2 αA/ CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia

2000 • 333 citations

Negative Regulation of BMP/Smad Signaling by Tob in Osteoblasts

2000 • 326 citations

Vascular MAD s: Two novel MAD -related genes selectively inducible by flow in human vascular endothelium

1997 • 325 citations

Smads bind directly to the Jun family of AP-1 transcription factors

1999 • 324 citations

Transforming Growth Factor-β Inhibits Adipocyte Differentiation by Smad3 Interacting with CCAAT/Enhancer-binding Protein (C/EBP) and Repressing C/EBP Transactivation Function

2003 • 322 citations

Defective repression of c- myc in breast cancer cells: A loss at the core of the transforming growth factor β growth arrest program

2001 • 320 citations

Cooperative Inhibition of Bone Morphogenetic Protein Signaling by Smurf1 and Inhibitory Smads

2003 • 316 citations

Crystal structure of the BMP-2–BRIA ectodomain complex

2000 • 314 citations

TGFβ receptor internalization into EEA1-enriched early endosomes

2002 • 298 citations

Crystal Structure of a Phosphorylated Smad2

2001 • 295 citations

Casein Kinase I

1998 • 294 citations

Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type β signaling

2001 • 291 citations

Smad2 transduces common signals from receptor serine–threonine and tyrosine kinases

1998 • 291 citations

Structural Basis of Smad2 Recognition by the Smad Anchor for Receptor Activation

2000 • 291 citations

Smad6 Is a Smad1/5-induced Smad Inhibitor

2000 • 277 citations

Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif

2000 • 277 citations

Opposing functions of ZEB proteins in the regulation of the TGFbeta/BMP signaling pathway

2003 • 275 citations

Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells

2001 • 270 citations

The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors

1998 • 265 citations

The BMP7/ActRII Extracellular Domain Complex Provides New Insights into the Cooperative Nature of Receptor Assembly

2003 • 264 citations

SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor β signaling

1999 • 252 citations

Cross-talk between Transforming Growth Factor-β and Estrogen Receptor Signaling through Smad3

2001 • 250 citations

The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway

2001 • 246 citations

Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation

2003 • 245 citations

ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling

2003 • 241 citations

c-myc Is a Downstream Target of the Smad Pathway

2002 • 238 citations

Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells

2004 • 236 citations

Alternatively Spliced Variant of Smad2 Lacking Exon 3

1999 • 235 citations

The corepressor CtBP interacts with Evi-1 to repress transforming growth factor β signaling

2001 • 230 citations

Characterization of Human FAST-1, a TGFβ and Activin Signal Transducer

1998 • 230 citations

Direct Interaction of c-Myc with Smad2 and Smad3 to Inhibit TGF-β-Mediated Induction of the CDK Inhibitor p15Ink4B

2002 • 224 citations

The N domain of Smad7 is essential for specific inhibition of transforming growth factor-β signaling

2001 • 221 citations

Transforming Growth Factor β-Mediated Transcriptional Repression of c-myc Is Dependent on Direct Binding of Smad3 to a Novel Repressive Smad Binding Element

2004 • 219 citations

The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse

2001 • 219 citations

Smad1 Recognition and Activation by the ALK1 Group of Transforming Growth Factor-β Family Receptors

1999 • 219 citations

DRAGON, a Bone Morphogenetic Protein Co-receptor

2005 • 218 citations

Crystal structure of the human TβR2 ectodomain–TGF-β3 complex

2002 • 215 citations

Ski and SnoN: negative regulators of TGF-β signaling

2003 • 215 citations

Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation

2003 • 205 citations

Molecular recognition of BMP-2 and BMP receptor IA

2004 • 205 citations

Structural Mechanism of Smad4 Recognition by the Nuclear Oncoprotein Ski

2002 • 204 citations

A kinase subdomain of transforming growth factor-β (TGF-β) type I receptor determines the TGF-β intracellular signaling specificity

1997 • 203 citations

FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse

2001 • 201 citations

Smad4 and β-Catenin Co-activators Functionally Interact with Lymphoid-enhancing Factor to Regulate Graded Expression of Msx2

2003 • 201 citations

Smurf1 Regulates the Inhibitory Activity of Smad7 by Targeting Smad7 to the Plasma Membrane

2002 • 195 citations

SMAD3 represses androgen receptor-mediated transcription.

2001 • 194 citations

Structural Basis of Heteromeric Smad Protein Assembly in TGF-β Signaling

2004 • 194 citations

The Androgen Receptor Represses Transforming Growth Factor-β Signaling through Interaction with Smad3

2002 • 189 citations

Foxh1 Is Essential for Development of the Anterior Heart Field

2004 • 188 citations

Smad1 Interacts with Homeobox DNA-binding Proteins in Bone Morphogenetic Protein Signaling

1999 • 187 citations

A Novel Mechanism for Regulating Transforming Growth Factor β (TGF-β) Signaling

2001 • 186 citations

Characterization of a Bone Morphogenetic Protein-responsive Smad-binding Element

2000 • 182 citations

Regulation of Smad signaling by protein kinase C

2001 • 179 citations

The Smad4 Activation Domain (SAD) Is a Proline-rich, p300-dependent Transcriptional Activation Domain

2000 • 177 citations

Hgs (Hrs), a FYVE Domain Protein, Is Involved in Smad Signaling through Cooperation with SARA

2000 • 176 citations

MEKK-1, a Component of the Stress (Stress-activated Protein Kinase/c-Jun N-terminal Kinase) Pathway, Can Selectively Activate Smad2-mediated Transcriptional Activation in Endothelial Cells

1999 • 171 citations

STRAP and Smad7 Synergize in the Inhibition of Transforming Growth Factor β Signaling

2000 • 171 citations

Glucocorticoid receptor inhibits transforming growth factor-β signaling by directly targeting the transcriptional activation function of Smad3

1999 • 169 citations

The Cardiac Determination Factor, Nkx2-5, Is Activated by Mutual Cofactors GATA-4 and Smad1/4 via a Novel Upstream Enhancer

2004 • 163 citations

Nuclear Factor YY1 Inhibits Transforming Growth Factor β- and Bone Morphogenetic Protein-Induced Cell Differentiation

2003 • 160 citations

Axin Facilitates Smad3 Activation in the Transforming Growth Factor β Signaling Pathway

2001 • 159 citations

A component of the ARC/Mediator complex required for TGFβ/Nodal signalling

2002 • 158 citations

Interferon-γ Interferes with Transforming Growth Factor-β Signaling through Direct Interaction of YB-1 with Smad3

2003 • 157 citations

Physical and Functional Interaction of Murine and Xenopus Smad7 with Bone Morphogenetic Protein Receptors and Transforming Growth Factor-β Receptors

1998 • 156 citations

Efficient TGF-β Induction of the Smad7 Gene Requires Cooperation between AP-1, Sp1, and Smad Proteins on the Mouse Smad7 Promoter

2000 • 155 citations

Specificity in transforming growth factor β-induced transcription of the plasminogen activator inhibitor-1 gene: Interactions of promoter DNA, transcription factor μE3, and Smad proteins

1999 • 155 citations

Smad6 as a Transcriptional Corepressor

2000 • 152 citations

Smad and AML Proteins Synergistically Confer Transforming Growth Factor β1 Responsiveness to Human Germ-line IgA Genes

2000 • 148 citations

Interaction of Smad3 and SRF-associated complex mediates TGF-β1 signals to regulate SM22 transcription during myofibroblast differentiation

2003 • 144 citations

Early Endosomal Regulation of Smad-dependent Signaling in Endothelial Cells

2002 • 143 citations

The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization.

2001 • 141 citations

TGF-β-activated Smad3 represses MEF2-dependent transcription in myogenic differentiation

2004 • 140 citations

Transcriptional activating activity of Smad4: Roles of SMAD hetero-oligomerization and enhancement by an associating transactivator

1998 • 139 citations

Smad3 allostery links TGF-β receptor kinase activation to transcriptional control

2002 • 136 citations

A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction.

2000 • 132 citations

Transcriptional Regulation of the Transforming Growth Factor-β-inducible Mouse Germ Line Ig α Constant Region Gene by Functional Cooperation of Smad, CREB, and AML Family Members

2000 • 132 citations

A Flexible Activin Explains the Membrane-Dependent Cooperative Assembly of TGF-β Family Receptors

2004 • 126 citations

Ski represses bone morphogenic protein signaling inXenopusand mammalian cells

2000 • 125 citations

Identification of Important Regions in the Cytoplasmic Juxtamembrane Domain of Type I Receptor That Separate Signaling Pathways of Transforming Growth Factor-β

1996 • 125 citations

A novel Smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-β signal transduction

2000 • 121 citations

Schnurri mediates Dpp-dependent repression of brinker transcription

2000 • 119 citations

Distinct Oligomeric States of SMAD Proteins in the Transforming Growth Factor-β Pathway

2000 • 118 citations

Oncogenic Ras Represses Transforming Growth Factor-β/Smad Signaling by Degrading Tumor Suppressor Smad4

2001 • 115 citations

The transcriptional co-activator P/CAF potentiates TGF-beta/Smad signaling

2000 • 112 citations

Smad Transcriptional Corepressors in TGFβ Family Signaling

2001 • 109 citations

Interaction and Functional Cooperation of NF-κB with Smads

2000 • 109 citations

The Functional Interaction between the Paired Domain Transcription Factor Pax8 and Smad3 Is Involved in Transforming Growth Factor-β Repression of the Sodium/Iodide Symporter Gene

2004 • 109 citations

fast1 is required for the development of dorsal axial structures in zebrafish

2000 • 109 citations

Smad6 Recruits Transcription Corepressor CtBP To Repress Bone Morphogenetic Protein-Induced Transcription

2003 • 107 citations

Smad-Dependent Recruitment of a Histone Deacetylase/Sin3A Complex Modulates the Bone Morphogenetic Protein-Dependent Transcriptional Repressor Activity of Nkx3.2

2003 • 107 citations

Smad4 as a Transcription Corepressor for Estrogen Receptor α

2003 • 106 citations

Structural Basis of Smad1 Activation by Receptor Kinase Phosphorylation

2001 • 106 citations

Structural and Functional Characterization of the Transforming Growth Factor-β-induced Smad3/c-Jun Transcriptional Cooperativity

2000 • 105 citations

Differential Modulation of Androgen Receptor-mediated Transactivation by Smad3 and Tumor Suppressor Smad4

2002 • 105 citations

A Nuclear Antagonistic Mechanism of Inhibitory Smads in Transforming Growth Factor-β Signaling

2002 • 104 citations

Physical and Functional Interaction between GATA-3 and Smad3 Allows TGF-β Regulation of GATA Target Genes

2002 • 98 citations

Smad1, β-catenin and Tcf4 associate in a molecular complex with the Myc promoter in dysplastic renal tissue and cooperate to control Myc transcription

2004 • 94 citations

The Murine Gastrin Promoter Is Synergistically Activated by Transforming Growth Factor-β/Smad and Wnt Signaling Pathways

2004 • 93 citations

Different Smad2 partners bind a common hydrophobic pocket in Smad2 via a defined proline-rich motif

2002 • 91 citations

Repression of Bone Morphogenetic Protein and Activin-inducible Transcription by Evi-1

2005 • 91 citations

Stoichiometry of Active Smad-Transcription Factor Complexes on DNA

2002 • 90 citations

SMIF, a Smad4-interacting protein that functions as a co-activator in TGFβ signalling

2002 • 90 citations

Cross-Talk between Bone Morphogenic Proteins and Estrogen Receptor Signaling

2002 • 88 citations

GATA- and Smad1-Dependent Enhancers in the Smad7 Gene Differentially Interpret Bone Morphogenetic Protein Concentrations

2003 • 88 citations

Ubiquitination and Proteolysis of Cancer-Derived Smad4 Mutants by SCF^Skp2

2004 • 85 citations

Formation of a Stable Heterodimer between Smad2 and Smad4

2001 • 85 citations

Ski-interacting Protein Interacts with Smad Proteins to Augment Transforming Growth Factor-β-dependent Transcription

2001 • 80 citations

Retinoic acid receptors interfere with the TGF-β/Smad signaling pathway in a ligand-specific manner

2003 • 79 citations

A Direct Intersection between p53 and Transforming Growth Factor β Pathways Targets Chromatin Modification and Transcription Repression of the α-Fetoprotein Gene

2005 • 78 citations

SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6-dependent chickNkx2.5enhancer

2004 • 76 citations

Interplay between the tumor suppressor p53 and TGFβ signaling shapes embryonic body axes inXenopus

2003 • 74 citations

The Zinc Finger Protein Schnurri Acts as a Smad Partner in Mediating the Transcriptional Response to Decapentaplegic

2000 • 72 citations

Decorin suppresses transforming growth factor-β-induced expression of plasminogen activator inhibitor-1 in human mesangial cells through a mechanism that involves Ca2+-dependent phosphorylation of Smad2 at serine-240

2002 • 70 citations

Synergism between Transcription Factors TFE3 and Smad3 in Transforming Growth Factor-β-induced Transcription of theSmad7 Gene

2000 • 69 citations

Transforming Growth Factor β/Smad3 Signaling Regulates IRF-7 Function and Transcriptional Activation of the Beta Interferon Promoter

2004 • 69 citations

Roles for the MH2 Domain of Smad7 in the Specific Inhibition of Transforming Growth Factor-β Superfamily Signaling

2004 • 66 citations

Smad Proteins Suppress CCAAT/Enhancer-binding Protein (C/EBP) β- and STAT3-mediated Transcriptional Activation of the Haptoglobin Promoter

2001 • 65 citations

Recognition of Phosphorylated-Smad2-Containing Complexes by a Novel Smad Interaction Motif

2004 • 63 citations

Tob proteins enhance inhibitory Smad-receptor interactions to repress BMP signaling

2003 • 61 citations

Regulation of transforming growth factor‐β and bone morphogenetic protein signalling by transcriptional coactivator GCN5

2004 • 59 citations

In the Absence of Type III Receptor, the Transforming Growth Factor (TGF)-β Type II-B Receptor Requires the Type I Receptor to Bind TGF-β2

2004 • 57 citations

The 1.1 Å Crystal Structure of Human TGF-β Type II Receptor Ligand Binding Domain

2002 • 53 citations

Phosphorylation of Smad7 at Ser-249 Does Not Interfere with Its Inhibitory Role in Transforming Growth Factor-β-dependent Signaling but Affects Smad7-dependent Transcriptional Activation

2001 • 51 citations

The Smad3 linker region contains a transcriptional activation domain

2005 • 51 citations

Mechanism of a Transcriptional Cross Talk between Transforming Growth Factor-β–regulated Smad3 and Smad4 Proteins and Orphan Nuclear Receptor Hepatocyte Nuclear Factor-4

2003 • 51 citations

The rasGAP-binding protein, Dok-1, mediates activin signaling via serine/threonine kinase receptors

2002 • 49 citations

Homeoprotein DLX-1 interacts with Smad4 and blocks a signaling pathway from activin A in hematopoietic cells

2003 • 47 citations

Casein Kinase Iϵ Plays a Functional Role in the Transforming Growth Factor-β Signaling Pathway

2004 • 45 citations

Swift Is a Novel BRCT Domain Coactivator of Smad2 in Transforming Growth Factor β Signaling

2001 • 44 citations

Both Max and TFE3 Cooperate with Smad Proteins to Bind the Plasminogen Activator Inhibitor-1 Promoter, but They Have Opposite Effects on Transcriptional Activity

2003 • 42 citations

An Essential Role for Mad Homology Domain 1 in the Association of Smad3 with Histone Deacetylase Activity*

2001 • 39 citations

Interaction between TGFβ Signaling Proteins and C/EBP Controls Basal and Tat-Mediated Transcription of HIV-1 LTR in Astrocytes

2002 • 38 citations

The interaction of BMP-7 and ActRII implicates a new mode of receptor assembly

2003 • 33 citations

Identification of novel Smad binding proteins

2003 • 30 citations

Cross-Talk between Bone Morphogenic Proteins and Estrogen Receptor Signaling

2002 • 24 citations

bcn-1 Element-dependent Activation of the Laminin γ1 Chain Gene by the Cooperative Action of Transcription Factor E3 (TFE3) and Smad Proteins

2002 • 17 citations

A molecular basis for Smad specificity

1999 • 14 citations

A molecular basis for Smad specificity

1999 • 10 citations