Smad1 Interacts with Homeobox DNA-binding Proteins in Bone Morphogenetic Protein Signaling

TGF-β signalling from cell membrane to nucleus through SMAD proteins

1997 • 3,650 citations

Molecular Mechanisms Mediating Proliferation/Differentiation Interrelationships During Progressive Development of the Osteoblast Phenotype

1993 • 1,021 citations

Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways

1996 • 899 citations

Receptor-associated Mad homologues synergize as effectors of the TGF-β response

1996 • 874 citations

MADR1, a MAD-Related Protein That Functions in BMP2 Signaling Pathways

1996 • 710 citations

Purification and characterization of other distinct bone-inducing factors.

1988 • 621 citations

Smad4 and FAST-1 in the assembly of activin-responsive factor

1997 • 567 citations

Smad2 and Smad3 Positively and Negatively Regulate TGFβ-Dependent Transcription through the Forkhead DNA-Binding Protein FAST2

1998 • 513 citations

Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb

1994 • 465 citations

Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene

1992 • 364 citations

Expression of Human Bone Morphogenetic Proteins-2 or -4 in Murine Mesenchymal Progenitor C3H10T½ Cells Induces Differentiation into Distinct Mesenchymal Cell Lineages

1993 • 340 citations

Smad5 and DPC4 Are Key Molecules in Mediating BMP-2-induced Osteoblastic Differentiation of the Pluripotent Mesenchymal Precursor Cell Line C2C12

1998 • 319 citations

Synergistic cooperation of TFE3 and Smad proteins in TGF-β-induced transcription of the plasminogen activator inhibitor-1 gene

1998 • 288 citations

Specific and redundant functions of the paralogous Hoxa-9 and Hoxd-9 genes in forelimb and axial skeleton patterning

1996 • 259 citations

Ectopic expression of Hoxb-8 causes duplication of the ZPA in the forelimb and homeotic transformation of axial structures

1994 • 245 citations

PARALOGOUS HOX GENES: Function and Regulation

1996 • 226 citations

Epithelial-mesenchymal interactions are required formsx 1andmsx 2gene expression in the developing murine molar tooth

1993 • 224 citations

Hox9 genes and vertebrate limb specification

1997 • 214 citations

Transcriptional Repression by Msx-1 Does Not Require Homeodomain DNA-Binding Sites

1995 • 172 citations

The murine gene encoding secreted phosphoprotein 1 (osteopontin): promoter structure, activity, and induction in vivo by estrogen and progesterone

1991 • 169 citations

Regulation of Msx-1, Msx-2, Bmp-2 and Bmp-4 during foetal and postnatal mammary gland development

1996 • 164 citations

Xom: a Xenopus homeobox gene that mediates the early effects of BMP-4

1996 • 159 citations

BMP-4-responsive regulation of dorsal–ventral patterning by the homeobox protein Mix.1

1996 • 152 citations

Hox genes in evolution: protein surfaces and paralog groups

1997 • 134 citations

Comparison of MSX-1 and MSX-2 suggests a molecular basis for functional redundancy

1996 • 131 citations

Cloning of the promoter for the avian integrin beta 3 subunit gene and its regulation by 1,25-dihydroxyvitamin D3.

1993 • 127 citations

Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development.

1987 • 123 citations

Retinoid signaling is required for the establishment of a ZPA and for the expression of Hoxb-8, a mediator of ZPA formation

1997 • 109 citations

The Tlx-2 homeobox gene is a downstream target of BMP signalling and is required for mouse mesoderm development

1998 • 106 citations

Loss of Function of the Homeobox Gene Hoxa-9 Perturbs Early T-Cell Development and Induces Apoptosis in Primitive Thymocytes

1998 • 100 citations

Activity of the rat osteocalcin basal promoter in osteoblastic cells is dependent upon homeodomain and CP1 binding motifs.

1994 • 98 citations

Evidence for regulation of cartilage differentiation by the homeobox gene Hoxc-8

1998 • 96 citations

Conservation of a functional hierarchy between mammalian and insect Hox/HOM genes.

1994 • 78 citations

Pattern of transcription of the homeo gene Hox-3.1 in the mouse embryo.

1988 • 72 citations

Detection of a Novel Cell Cycle-regulated Kinase Activity That Associates with the Amino Terminus of the Retinoblastoma Protein in G2/M Phases

1995 • 50 citations

Hematopoietic progenitor cell abnormalities in Hoxc-8 null mutant mice

1999 • 32 citations

The HOX-11 (TCL-3) homeobox proto-oncogene encodes a nuclear protein that undergoes cell cycle-dependent regulation.

1993 • 16 citations