SARA, a FYVE Domain Protein that Recruits Smad2 to the TGFβ Receptor

TGF-β signalling from cell membrane to nucleus through SMAD proteins

1997 • 3,650 citations

Mechanism of activation of the TGF-β receptor

1994 • 2,298 citations

Signaling Through Scaffold, Anchoring, and Adaptor Proteins

1997 • 2,268 citations

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

1998 • 1,101 citations

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

1997 • 1,023 citations

Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways

1996 • 899 citations

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcription

1998 • 789 citations

MADR2 Is a Substrate of the TGFβ Receptor and Its Phosphorylation Is Required for Nuclear Accumulation and Signaling

1996 • 740 citations

MADR1, a MAD-Related Protein That Functions in BMP2 Signaling Pathways

1996 • 710 citations

A transcriptional partner for MAD proteins in TGF-β signalling

1996 • 699 citations

A Mammalian Scaffold Complex That Selectively Mediates MAP Kinase Activation

1998 • 653 citations

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase.

1997 • 569 citations

Smad4 and FAST-1 in the assembly of activin-responsive factor

1997 • 567 citations

The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules.

1995 • 556 citations

Smad2 and Smad3 Positively and Negatively Regulate TGFβ-Dependent Transcription through the Forkhead DNA-Binding Protein FAST2

1998 • 513 citations

TGF-β-stimulated cooperation of Smad proteins with the coactivators CBP/p300

1998 • 503 citations

Phosphatidylinositol(3)-Phosphate Signaling Mediated by Specific Binding to RING FYVE Domains

1998 • 497 citations

Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors

1992 • 495 citations

SMADs: mediators and regulators of TGF-β signaling

1998 • 476 citations

Specific Activation of Smad1 Signaling Pathways by the BMP7 Type I Receptor, ALK2

1998 • 472 citations

MP1: A MEK Binding Partner That Enhances Enzymatic Activation of the MAP Kinase Cascade

1998 • 471 citations

TβRI Phosphorylation of Smad2 on Ser465 and Ser467 Is Required for Smad2-Smad4 Complex Formation and Signaling

1997 • 470 citations

Dual role of the Smad4/DPC4 tumor suppressor in TGFβ-inducible transcriptional complexes

1997 • 439 citations

Phosphorylation of Ser465 and Ser467 in the C Terminus of Smad2 Mediates Interaction with Smad4 and Is Required for Transforming Growth Factor-β Signaling

1997 • 383 citations

Transforming growth factor β-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells

1997 • 357 citations

Vascular MAD s: Two novel MAD -related genes selectively inducible by flow in human vascular endothelium

1997 • 325 citations

Smad5 and DPC4 Are Key Molecules in Mediating BMP-2-induced Osteoblastic Differentiation of the Pluripotent Mesenchymal Precursor Cell Line C2C12

1998 • 319 citations

The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function

1997 • 317 citations

Molecular Glue: Kinase Anchoring and Scaffold Proteins

1996 • 264 citations

Characterization of Human FAST-1, a TGFβ and Activin Signal Transducer

1998 • 230 citations

The Interpretation of Position in a Morphogen Gradient as Revealed by Occupancy of Activin Receptors

1998 • 205 citations

The types II and III transforming growth factor-beta receptors form homo-oligomers.

1994 • 199 citations

Mads and Smads in TGFβ signalling

1998 • 194 citations

Smad8 mediates the signaling of the receptor serine kinase

1997 • 155 citations

Oligomeric Structure of Type I and Type II Transforming Growth Factor β Receptors: Homodimers Form in the ER and Persist at the Plasma Membrane

1998 • 139 citations