Structural Basis of Smad2 Recognition by the Smad Anchor for Receptor Activation

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

TGF-β SIGNAL TRANSDUCTION

1998 • 7,582 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

AMoRe: an automated package for molecular replacement

1994 • 4,990 citations

TGF-β signalling from cell membrane to nucleus through SMAD proteins

1997 • 3,650 citations

Mechanism of activation of the TGF-β receptor

1994 • 2,298 citations

SARA, a FYVE Domain Protein that Recruits Smad2 to the TGFβ Receptor

1998 • 952 citations

Crystal structure of the p27Kip1 cyclin-dependent-kinase inibitor bound to the cyclin A–Cdk2 complex

1996 • 889 citations

The Transforming Growth Factor-βs

1990 • 741 citations

A transcriptional partner for MAD proteins in TGF-β signalling

1996 • 699 citations

GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex.

1995 • 682 citations

A structural basis for mutational inactivation of the tumour suppressor Smad4

1997 • 459 citations

Crystal Structure of the Cytoplasmic Domain of the Type I TGF β Receptor in Complex with FKBP12

1999 • 433 citations

Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasis

1999 • 430 citations

Determinants of specificity in TGF-β signal transduction

1998 • 364 citations

The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors

1998 • 265 citations

A kinase subdomain of transforming growth factor-β (TGF-β) type I receptor determines the TGF-β intracellular signaling specificity

1997 • 203 citations

Transforming Growth Factor-β (TGF-β)-induced Down-regulation of Cyclin A Expression Requires a Functional TGF-β Receptor Complex

1995 • 154 citations

Formation and activation by phosphorylation of activin receptor complexes.

1996 • 97 citations

FAST-2 Is a Mammalian Winged-Helix Protein Which Mediates Transforming Growth Factor β Signals

1999 • 88 citations