Swift Is a Novel BRCT Domain Coactivator of Smad2 in Transforming Growth Factor β Signaling

TGF-β SIGNAL TRANSDUCTION

1998 • 7,582 citations

Mammalian Ras interacts directly with the serine/threonine kinase raf

1993 • 1,983 citations

NEW EMBO MEMBERS REVIEW: Transcriptional control by the TGF-beta/Smad signaling system

2000 • 1,935 citations

GAL4-VP16 is an unusually potent transcriptional activator

1988 • 1,379 citations

Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos

1992 • 1,176 citations

Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryos

1991 • 1,103 citations

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

2000 • 960 citations

A transcriptional partner for MAD proteins in TGF-β signalling

1996 • 699 citations

Smad3 Mutant Mice Develop Metastatic Colorectal Cancer

1998 • 677 citations

Smad4 and FAST-1 in the assembly of activin-responsive factor

1997 • 567 citations

Regulation of Cell–Cell Adhesion by Rac and Rho Small G Proteins in MDCK Cells

1997 • 555 citations

A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos

1992 • 538 citations

The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for Smad3 in TGF-β-induced transcriptional activation

1998 • 527 citations

From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair

1997 • 525 citations

Smad2 and Smad3 Positively and Negatively Regulate TGFβ-Dependent Transcription through the Forkhead DNA-Binding Protein FAST2

1998 • 513 citations

Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate

1990 • 508 citations

TGF-β-stimulated cooperation of Smad proteins with the coactivators CBP/p300

1998 • 503 citations

Responses of embryonic xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm

1992 • 486 citations

The p300/CBP family: integrating signals with transcription factors and chromatin

1997 • 482 citations

Xenopus Mad Proteins Transduce Distinct Subsets of Signals for the TGFβ Superfamily

1996 • 432 citations

Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1

1997 • 354 citations

Physical and Functional Interaction of SMADs and p300/CBP

1998 • 351 citations

Regulation of Wnt Signaling by Sox Proteins

1999 • 342 citations

Activin signalling and response to a morphogen gradient

1994 • 328 citations

Inhibition of Xbra transcription activation causes defects in mesodermal patterning and reveals autoregulation of Xbra in dorsal mesoderm

1996 • 280 citations

Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif

2000 • 277 citations

Endogenous patterns of TGFβ superfamily signaling during early Xenopus development

2000 • 256 citations

Active repression of transcription by the engrailed homeodomain protein.

1991 • 248 citations

Eomesodermin, a Key Early Gene in Xenopus Mesoderm Differentiation

1996 • 241 citations

Characterization of Human FAST-1, a TGFβ and Activin Signal Transducer

1998 • 230 citations

Mesoderm induction by activin requires FGF-mediated intracellular signals

1994 • 225 citations

Mixer , a Homeobox Gene Required for Endoderm Development

1998 • 206 citations

FAST-1 is a key maternal effector of mesoderm inducers in the early Xenopus embryo

1999 • 118 citations

Activin has direct long-range signalling activity and can form a concentration gradient by diffusion

1997 • 107 citations

cDNAs with long CAG trinucleotide repeats from human brain

1997 • 103 citations

A quantitative analysis of signal transduction from activin receptor to nucleus and its relevance to morphogen gradient interpretation

1999 • 90 citations

A novel Xenopus Mix-like gene milk involved in the control of the endomesodermal fates

1998 • 89 citations

Neural induction in Xenopus laevis: evidence for the default model

1997 • 83 citations

The ALK-2 and ALK-4 activin receptors transduce distinct mesoderm-inducing signals during earlyXenopusdevelopment but do not co-operate to establish thresholds

1997 • 83 citations

Dominant-Negative Smad2 Mutants Inhibit Activin/Vg1 Signaling and Disrupt Axis Formation in Xenopus

1999 • 77 citations

PTIP, a novel BRCT domain-containing protein interacts with Pax2 and is associated with active chromatin

2000 • 76 citations

Conservation of Glutamine-Rich Transactivation Function between Yeast and Humans

2000 • 67 citations

XBMPRII, a novel Xenopus type II receptor mediating BMP signaling in embryonic tissues

1998 • 61 citations

Neuralization of the Xenopus embryo by inhibition of p300/ CREB-binding protein function.

1999 • 38 citations

Neuralization of theXenopusEmbryo by Inhibition of p300/ CREB-Binding Protein Function

1999 • 31 citations

A transcriptional partner for MAD proteins in TGF-β signalling

1997 • 19 citations

Cell-Free Assay System for Ras- and Rap1 -Dependent Activation of MAP-Kinase Cascade

2003 • 2 citations