Apoptosis in AIDS.

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1972 • 15,349 citations

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1995 • 4,310 citations

HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time

1996 • 3,496 citations

Viral dynamics in human immunodeficiency virus type 1 infection

1995 • 3,277 citations

Checkpoints: Controls That Ensure the Order of Cell Cycle Events

1989 • 3,036 citations

NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation

1998 • 2,698 citations

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1995 • 2,106 citations

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

1991 • 1,613 citations

The Human Immunodeficiency Virus: Infectivity and Mechanisms of Pathogenesis

1988 • 1,496 citations

Vpr Is Required for Efficient Replication of Human Immunodeficiency Virus Type-1 in Mononuclear Phagocytes

1995 • 1,252 citations

A Novel CDK9-Associated C-Type Cyclin Interacts Directly with HIV-1 Tat and Mediates Its High-Affinity, Loop-Specific Binding to TAR RNA

1998 • 1,213 citations

Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

1996 • 1,041 citations

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes

1998 • 1,012 citations

Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120

1995 • 983 citations

Programmed Death of T Cells in HIV-1 Infection

1992 • 932 citations

Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals.

1992 • 907 citations

Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients

1990 • 899 citations

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

1995 • 885 citations

The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells.

1994 • 845 citations

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

1991 • 760 citations

Membrane and Morphological Changes in Apoptotic Cells Regulated by Caspase-Mediated Activation of PAK2

1997 • 742 citations

Nef induces CD4 endocytosis: Requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

1994 • 701 citations

Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis.

1992 • 689 citations

Molecular Characterization of Human T-Cell Leukemia (Lymphotropic) Virus Type III in the Acquired Immune Deficiency Syndrome

1984 • 639 citations

When Checkpoints Fail

1997 • 622 citations

Induction of Apoptosis in Uninfected Lymphocytes by HIV-1 Tat Protein

1995 • 581 citations

Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4

1992 • 553 citations

Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis

1991 • 548 citations

Long-Term Cultures of HTLV-III—Infected T Cells: a Model of Cytopathology of T-Cell Depletion in AIDS

1986 • 537 citations

The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle

1995 • 518 citations

HIV-1 Vpr increases viral expression by manipulation of the cell cycle: A mechanism for selection of Vpr in vivo

1998 • 506 citations

Endocytosis and targeting of exogenous HIV-1 Tat protein.

1991 • 481 citations

The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release

1990 • 461 citations

The HIV-1 Viral Protein R Induces Apoptosis via a Direct Effect on the Mitochondrial Permeability Transition Pore

2000 • 449 citations

Vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells

1993 • 449 citations

Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes

1992 • 447 citations

Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1.

1991 • 432 citations

The human immunodeficiency virus type 1 vpr gene prevents cell proliferation during chronic infection

1995 • 411 citations

Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4

1998 • 411 citations

Signal Transduction Due to HIV-1 Envelope Interactions with Chemokine Receptors CXCR4 or CCR5

1997 • 394 citations

HIV-1 Tat potentiates TNF-induced NF-kappa B activation and cytotoxicity by altering the cellular redox state.

1995 • 386 citations

Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis

1995 • 385 citations

Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B

1995 • 382 citations

Human immunodeficiency virus vpr product is a virion-associated regulatory protein

1990 • 363 citations

The cytopathic effect of hiv is associated with apoptosis

1991 • 358 citations

Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor

1997 • 357 citations

Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arrest

1997 • 348 citations

Viral protein R regulates nuclear import of the HIV-1 pre-integration complex

1998 • 320 citations

Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes

1996 • 316 citations

The T Cell Activation Factor NF-ATc Positively Regulates HIV-1 Replication and Gene Expression in T Cells

1997 • 313 citations

Constitutive Activation of NF-κB Causes Resistance to Apoptosis in Human Cutaneous T Cell Lymphoma HuT-78 Cells

1998 • 300 citations

Foundations in Cancer Research p53 and ATM: Cell Cycle, Cell Death, and Cancer

1997 • 300 citations

Effects of the human immunodeficiency virus type 1 Tat protein on the expression of inflammatory cytokines

1992 • 289 citations

Human immunodeficiency virus type 1 Nef increases the efficiency of reverse transcription in the infected cell

1995 • 266 citations

Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr

1995 • 260 citations

Coreceptors--Implications for HIV Pathogenesis and Therapy

1997 • 258 citations

Human immunodeficiency virus type 1 cell cycle control: Vpr is cytostatic and mediates G2 accumulation by a mechanism which differs from DNA damage checkpoint control

1996 • 253 citations

Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import

1996 • 253 citations

The expression of the interleukin 6 gene is induced by the human immunodeficiency virus 1 TAT protein.

1994 • 250 citations

Induction of Fas Ligand Expression by HIV Involves the Interaction of Nef with the T Cell Receptor ζ Chain

1999 • 242 citations

Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals

1993 • 242 citations

HIV-1 Vpr suppresses immune activation and apoptosis through regulation of nuclear factor κB

1997 • 240 citations

An Endogenous Inhibitor of Human Immunodeficiency Virus in Human Lymphocytes Is Overcome by the Viral Vif Protein

1998 • 238 citations

Distinct Effects in Primary Macrophages and Lymphocytes of the Human Immunodeficiency Virus Type 1 Accessory Genes vpr, vpu, and nef: Mutational Analysis of a Primary HIV-1 Isolate

1994 • 237 citations

Human immunodeficiency virus type 1 Nef associateswith a cellular serine kinase in T lymphocytes.

1994 • 227 citations

Cross-linking of CD4 molecules upregulates Fas antigen expression in lymphocytes by inducing interferon-gamma and tumor necrosis factor- alpha secretion

1994 • 220 citations

Tat protein of human immunodeficiency virus type 1 represses expression of manganese superoxide dismutase in HeLa cells.

1993 • 212 citations

Membrane Expression of HIV Envelope Glycoproteins Triggers Apoptosis in CD4 Cells

1993 • 210 citations

Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the chain of adaptor complexes

1998 • 209 citations

CXCR4 and CD4 mediate a rapid CD95-independent cell death in CD4⁺T cells

1998 • 202 citations

Evasion of Cytotoxic T Lymphocyte (CTL) Responses by Nef-dependent Induction of Fas Ligand (CD95L) Expression on Simian Immunodeficiency Virus–infected Cells

1997 • 194 citations

The Human Immunodeficiency Virus Type 1 (HIV-1) Vpu Protein Interferes with an Early Step in the Biosynthesis of Major Histocompatibility Complex (MHC) Class I Molecules

1997 • 193 citations

Vpr-induced cell cycle arrest is conserved among primate lentiviruses

1996 • 192 citations

Human Immunodeficiency Virus Type 1 Tat Induces Apoptosis and Increases Sensitivity to Apoptotic Signals by Up-Regulating FLICE/Caspase-8

1999 • 191 citations

Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef

1995 • 191 citations

Vpu protein of human immunodeficiency virus type 1 enhances the release of capsids produced by gag gene constructs of widely divergent retroviruses.

1993 • 189 citations

Cell-dependent requirement of human immunodeficiency virus type 1 Vif protein for maturation of virus particles

1993 • 188 citations

Mutational analysis of the human immunodeficiency virus vpr open reading frame

1989 • 183 citations

Interaction of the Human Immunodeficiency Virus Type 1 Vpr Protein with the Nuclear Pore Complex

1998 • 175 citations

Human immunodeficiency virus type 1 Vpr protein binds to the uracil DNA glycosylase DNA repair enzyme

1996 • 173 citations

Monocytes express Fas ligand upon CD4 cross-linking and induce CD4+ T cells apoptosis: a possible mechanism of bystander cell death in HIV infection.

1997 • 167 citations

The Interaction of Vpr with Uracil DNA Glycosylase Modulates the Human Immunodeficiency Virus Type 1 In Vivo Mutation Rate

2000 • 162 citations

Human Immunodeficiency Virus Type 1 Vpr Induces Apoptosis through Caspase Activation

2000 • 157 citations

Interactions of HIV-1 NEF with cellular signal transducing proteins

2000 • 156 citations

Human immunodeficiency virus type 1 Nef associates with a member of the p21-activated kinase family

1996 • 154 citations

Activation of transcription factor NF-kappaB by the Tat protein of human immunodeficiency virus type 1

1996 • 149 citations

Dual role of HIV Tat in regulation of apoptosis in T cells.

1997 • 142 citations

The Growth Advantage Conferred by HIV-1 nef Is Determined at the Level of Viral DNA Formation and Is Independent of CD4 Downregulation

1995 • 141 citations

Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry

1995 • 140 citations

The HIV-1 vpr Protein Acts as a Negative Regulator of Apoptosis in a Human Lymphoblastoid T Cell Line: Possible Implications for the Pathogenesis of AIDS

1998 • 136 citations

Identification of the Nef-associated kinase as p21-activated kinase 2

1999 • 132 citations

A domain of human immunodeficiency virus type 1 Vpr containing repeated H(S/F)RIG amino acid motifs causes cell growth arrest and structural defects.

1995 • 129 citations

Human immunodeficiency virus type 1 Tat protein protects lymphoid, epithelial, and neuronal cell lines from death by apoptosis.

1993 • 128 citations

HIV-1 envelope induces activation of caspase-3 and cleavage of focal adhesion kinase in primary human CD4⁺T cells

2000 • 128 citations

Extracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-kappa B binding and protein kinase C activity in primary human astrocytes

1996 • 127 citations

Human Immunodeficiency VirusvprGene Encodes a Virion-Associated Protein

1990 • 126 citations

The human immunodeficiency virus type-1 Tat protein upregulates Bcl-2 gene expression in Jurkat T-cell lines and primary peripheral blood mononuclear cells

1995 • 122 citations

Uracil DNA glycosylase specifically interacts with Vpr of both human immunodeficiency virus type 1 and simian immunodeficiency virus of sooty mangabeys, but binding does not correlate with cell cycle arrest

1997 • 120 citations

Human immunodeficiency virus type 1 Vif does not influence expression or virion incorporation of gag-, pol-, and env-encoded proteins

1996 • 116 citations

HIV-1 Tat Induces the Expression of the Interleukin-6 (IL6) Gene by Binding to the IL6 Leader RNA and by Interacting with CAAT Enhancer-binding Protein β (NF-IL6) Transcription Factors

1997 • 116 citations

Human Immunodeficiency Virus Type 1 Nef Protein Sensitizes CD4+ T Lymphoid Cells to Apoptosis via Functional Upregulation of the CD95/CD95 Ligand Pathway

1999 • 116 citations

HIV-Tat Protein Activates c-Jun N-Terminal Kinase and Activator Protein-1

1998 • 116 citations

Cell Cycle- and Vpr-Mediated Regulation of Human Immunodeficiency Virus Type 1 Expression in Primary and Transformed T-Cell Lines

1999 • 115 citations

Cooperative Interaction between HIV-1 Regulatory Proteins Tat and Vpr Modulates Transcription of the Viral Genome

2000 • 113 citations

Molecular Ordering in HIV-induced Apoptosis

1998 • 113 citations

Indirect mechanisms of HIV pathogenesis: how does HIV kill T cells?

1994 • 112 citations

HIV-1 tat gene induces tumor necrosis factor-beta (lymphotoxin) in a human B-lymphoblastoid cell line

1990 • 111 citations

Caspase-Dependent Apoptosis of Cells Expressing the Chemokine Receptor CXCR4 Is Induced by Cell Membrane-Associated Human Immunodeficiency Virus Type 1 Envelope Glycoprotein (gp120)

2000 • 107 citations

Inhibition of NF-kappa B activity in human T lymphocytes induces caspase-dependent apoptosis without detectable activation of caspase-1 and -3.

1999 • 105 citations

Human Immunodeficiency Virus Type 1 Tat Protein Activates Transcription Factor NF-κB through the Cellular Interferon-Inducible, Double-Stranded RNA-Dependent Protein Kinase, PKR

1999 • 104 citations

p21-Activated Kinase 1 Plays a Critical Role in Cellular Activation by Nef

2000 • 104 citations

Expression of human immunodeficiency virus type I tat results in down-regulation of bcl-2 and induction of apoptosis in hematopoietic cells.

1996 • 103 citations

HIV-1 gp120- and gp160-induced apoptosis in cultured endothelial cells is mediated by caspases

2000 • 103 citations

SH3-Domain Binding Function of HIV-1 Nef Is Required for Association with a PAK-Related Kinase

1998 • 102 citations

Activation of Transcription Factors NF-κB and NF-IL-6 by Human Immunodeficiency Virus Type 1 Protein R (Vpr) Induces Interleukin-8 Expression

2000 • 100 citations

Association of simian immunodeficiency virus Nef with the T-cell receptor (TCR) zeta chain leads to TCR down-modulation.

1998 • 98 citations

Human immunodeficiency virus type 1 Vpr interacts with HHR23A, a cellular protein implicated in nucleotide excision DNA repair

1997 • 94 citations

Expression kinetics and subcellular localization of HIV-1 regulatory proteins Nef, Tat and Rev in acutely and chronically infected lymphoid cell lines

1994 • 93 citations

A Conserved Dileucine-Containing Motif in p6 ^gag Governs the Particle Association of Vpx and Vpr of Simian Immunodeficiency Viruses SIV _mac and SIV _agm

1999 • 90 citations

Apoptosis induced in CD4+ cells expressing gp160 of human immunodeficiency virus type 1

1994 • 89 citations

T cell activation-induced and HIV Tat-enhanced CD95(APO-1 / Fas) ligand transcription involves NF-κB

2000 • 88 citations

Cyclin T1 domains involved in complex formation with tat and TAR RNA are critical for tat-activation

1999 • 88 citations

Pleiotropic effects of immobilized versus soluble recombinant HIV-1 Tat protein on CD3-mediated activation, induction of apoptosis, and HIV-1 long terminal repeat transactivation in purified CD4+ T lymphocytes.

1996 • 86 citations

Modulation of Bcl-2 Protein by CD4 Cross-Linking: A Possible Mechanism for Lymphocyte Apoptosis in Human Immunodeficiency Virus Infection and for Rescue of Apoptosis by Interleukin-2

1997 • 85 citations

The implication of the chemokine receptor CXCR4 in HIV-1 envelope protein-induced apoptosis is independent of the G protein-mediated signalling

1999 • 82 citations

HIV Type 1 Tat Protein Induces Apoptosis and Death in Jurkat Cells

1995 • 82 citations

Human immunodeficiency virus type 1 Vpu protein induces degradation of chimeric envelope glycoproteins bearing the cytoplasmic and anchor domains of CD4: role of the cytoplasmic domain in Vpu-induced degradation in the endoplasmic reticulum

1993 • 81 citations

Human immunodeficiency virus type 1 vpr gene induces phenotypic effects similar to those of the DNA alkylating agent, nitrogen mustard

1997 • 80 citations

Apoptotic cell death upon contact of CD4+ T lymphocytes with HIV glycoprotein-expressing cells is mediated by caspases but bypasses CD95 (Fas/Apo-1) and TNF receptor 1.

1997 • 79 citations

Mutational Analysis of Vpr-Induced G ₂ Arrest, Nuclear Localization, and Cell Death in Fission Yeast

1999 • 78 citations

CD4+ blood lymphocytes are rapidly killed in vitro by contact with autologous human immunodeficiency virus-infected cells.

1995 • 78 citations

Extracellular HIV‐1 Tat protein activates phosphatidylinositol 3‐ and Akt/PKB kinases in CD4⁺ T lymphoblastoid Jurkat cells

1997 • 77 citations

Susceptibility of HIV-1-TAT transfected cells to undergo apoptosis. Biochemical mechanisms

1999 • 76 citations

Priming of human CD4+ antigen-specific T cells to undergo apoptosis by HIV-infected monocytes. A two-step mechanism involving the gp120 molecule.

1997 • 75 citations

Zeta Chain of the T-Cell Receptor Interacts with nef of Simian Immunodeficiency Virus and Human Immunodeficiency Virus Type 2

1998 • 74 citations

Reciprocal Modulatory Interaction between Human Immunodeficiency Virus Type 1 Tat and Transcription Factor NFAT1

1999 • 72 citations

Roles of p53 and Caspases in the Induction of Cell Cycle Arrest and Apoptosis by HIV-1 vpr

1999 • 70 citations

Genetic Studies with the Fission Yeast Schizosaccharomyces pombe Suggest Involvement of Wee1, Ppa2, and Rad24 in Induction of Cell Cycle Arrest by Human Immunodeficiency Virus Type 1 Vpr

2000 • 67 citations

CD4 T lymphocytes are primed to express Fas ligand by CD4 cross-linking and to contribute to CD8 T-cell apoptosis via Fas/FasL death signaling pathway

2000 • 66 citations

The HIV‐1 Vpr displays strong anti‐apoptotic activity

1998 • 65 citations

Transcomplementation of VIF- HIV-1 Mutants in CEM Cells Suggests That VIF Affects Late Steps of the Viral Life Cycle

1993 • 61 citations

Dual Role of the HIV-1 Vpr Protein in the Modulation of the Apoptotic Response of T Cells

2000 • 60 citations

Arginine Residues in the C-terminus of HIV-1 Vpr Are Important for Nuclear Localization and Cell Cycle Arrest

1998 • 59 citations

Caspase-mediated activation of PAK2 during apoptosis: proteolytic kinase activation as a general mechanism of apoptotic signal transduction?

1998 • 58 citations

Fas (CD95) expression and death-mediating function are induced by CD4 cross-linking on CD4+ T cells.

1996 • 56 citations

An Autocrine Loop of HIV Type-1 Tat Protein Responsible for the Improved Survival/Proliferation Capacity of Permanently Tat-Transfected Cells and Required for Optimal HIV-1 LTR Transactivating Activity

1995 • 55 citations

HHR23A, the Human Homologue of the Yeast Repair Protein RAD23, Interacts Specifically with Vpr Protein and Prevents Cell Cycle Arrest but Not the Transcriptional Effects of Vpr

1998 • 54 citations

Human immunodeficiency virus type 1 Vpr localization: nuclear transport of a viral protein modulated by a putative amphipathic helical structure and its relevance to biological activity

1998 • 54 citations

Differential Requirement for p56lck in HIV-tat Versus TNF-Induced Cellular Responses: Effects on NF-κB, Activator Protein-1, c-Jun N-Terminal Kinase, and Apoptosis

2000 • 54 citations

Direct binding to nucleic acids by Vpr of human immunodeficiency virus type 1

1998 • 52 citations

Degradation of CD4 Induced by Human Immunodeficiency Virus Type 1 Vpu Protein: A Predicted Alpha-Helix Structure in the Proximal Cytoplasmic Region of CD4 Contributes to Vpu Sensitivity

1995 • 48 citations

Micronuclei formation and aneuploidy induced byVpr, an accessory gene of human immunodeficiency virus type 1

1999 • 46 citations

Induction of M-Phase Arrest and Apoptosis after HIV-1 Vpr Expression through Uncoupling of Nuclear and Centrosomal Cycle in HeLa Cells

2000 • 44 citations

Micronuclei formation with chromosome breaks and gene amplification caused by Vpr, an accessory gene of human immunodeficiency virus.

1999 • 43 citations

Activation of the PAK-Related Kinase by Human Immunodeficiency Virus Type 1 Nef in Primary Human Peripheral Blood Lymphocytes and Macrophages Leads to Phosphorylation of a PIX-p95 Complex

1999 • 43 citations

HIV Type 1 Glycoprotein 120 Amplifies Tumor Necrosis Factor-Induced NF-kB Activation in Jurkat Cells

1996 • 43 citations

HIV type 1 Tat protein enhances activation-but not Fas (CD95)-induced peripheral blood T cell apoptosis in healthy individuals

1997 • 41 citations

HIV‐1 protein Vpr causes gross mitochondrial dysfunction in the yeast Saccharomyces cerevisiae

1997 • 41 citations

The T-Cell Receptor ζ Chain Contains Two Homologous Domains with Which Simian Immunodeficiency Virus Nef Interacts and Mediates Down-Modulation

2000 • 38 citations

Induction of Fas Ligand Expression by an Acutely Lethal Simian Immunodeficiency Virus, SIVsmmPBj14

1998 • 34 citations

Engagement of CD4 Before TCR Triggering Regulates Both Bax- and Fas (CD95)-Mediated Apoptosis

2000 • 31 citations

Regulatory functions of Cdk9 and of cyclin T1 in HIV Tat transactivation pathway gene expression

1999 • 30 citations

Differential apoptosis effects of primate lentiviral Vpr and Vpx in mammalian cells

2000 • 25 citations

Activation of Bcl-2 Promoter-Directed Gene Expression by the Human Immunodeficiency Virus Type-1 Tat Protein

1999 • 23 citations

Multiple Centrosome Formation Induced by the Expression of Vpr Gene of Human Immunodeficiency Virus

1999 • 22 citations

The CD4 molecule transmits biochemical information important in the regulation of T lymphocyte activity

1990 • 21 citations

Role of the Conserved Dipeptide Gly75 and Cys76 on HIV-1 Vpr Function

1995 • 17 citations

Grb3-3 Is Up-regulated in HIV-1-infected T-cells and Can Potentiate Cell Activation through NFATc

2000 • 17 citations

Fas/FasL Interaction Is Not Involved in Apoptosis of Activated CD4+ T Cells Upon HIV-1 Infection in Vitro

1998 • 16 citations

Residues within the HFRIGC Sequence of HIV-1 Vpr Involved in Growth Arrest Activities

1999 • 15 citations

The Cell Death-Inducing Ability of Glycoprotein 120 from Different HIV Strains Correlates with Their Ability to Induce CD4 Lateral Association with CD95 on CD4+ T Cells

1999 • 14 citations

A Novel Kinase Activity Associated with Nef Derived from Neurovirulent Simian Immunodeficiency Virus

1998 • 9 citations

Human Immunodeficiency Virus Type 1-Associated Cd4 Downmodulation

1994 • 7 citations