HHR23A, the Human Homologue of the Yeast Repair Protein RAD23, Interacts Specifically with Vpr Protein and Prevents Cell Cycle Arrest but Not the Transcriptional Effects of Vpr

A novel genetic system to detect protein–protein interactions

1989 • 6,022 citations

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1997 • 2,100 citations

Cell Cycle Checkpoints: Preventing an Identity Crisis

1996 • 2,056 citations

Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

1993 • 1,531 citations

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

1997 • 1,300 citations

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

1995 • 885 citations

The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells.

1994 • 845 citations

rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA.

1989 • 634 citations

The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle

1995 • 518 citations

CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription.

1996 • 414 citations

The human immunodeficiency virus type 1 vpr gene prevents cell proliferation during chronic infection

1995 • 411 citations

AIDS: Etiology, Diagnosis, Treatment, and Prevention.

1985 • 407 citations

Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23.

1994 • 394 citations

Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B

1995 • 382 citations

Incorporation of Vpr into human immunodeficiency virus type 1 virions: requirement for the p6 region of gag and mutational analysis

1993 • 368 citations

Interaction mating reveals binary and ternary connections between Drosophila cell cycle regulators.

1994 • 306 citations

HIV accessory proteins: Leading roles for the supporting cast

1995 • 283 citations

Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr

1995 • 260 citations

Human immunodeficiency virus type 1 cell cycle control: Vpr is cytostatic and mediates G2 accumulation by a mechanism which differs from DNA damage checkpoint control

1996 • 253 citations

Identification of HIV-1 vpr product and function.

1990 • 251 citations

The Saccharomyces cerevisiae DNA repair gene RAD23 encodes a nuclear protein containing a ubiquitin-like domain required for biological function.

1993 • 246 citations

Progression to AIDS in the absence of a gene for vpr or vpx

1995 • 243 citations

Serum Vpr regulates productive infection and latency of human immunodeficiency virus type 1.

1994 • 241 citations

Distinct Effects in Primary Macrophages and Lymphocytes of the Human Immunodeficiency Virus Type 1 Accessory Genes vpr, vpu, and nef: Mutational Analysis of a Primary HIV-1 Isolate

1994 • 237 citations

Evolution of the primate lentiviruses: evidence from vpx and vpr.

1992 • 232 citations

Importance of vpr for infection of rhesus monkeys with simian immunodeficiency virus

1993 • 220 citations

Induction of cell differentiation by human immunodeficiency virus 1 vpr

1993 • 214 citations

The HIV-1 Virion-associated Protein Vpr Is a Coactivator of the Human Glucocorticoid Receptor

1999 • 210 citations

Human immunodeficiency virus type 1 Vpr protein binds to the uracil DNA glycosylase DNA repair enzyme

1996 • 173 citations

Cushing's disease preceded by generalized glucocorticoid resistance: clinical consequences of a novel, dominant-negative glucocorticoid receptor mutation.

1996 • 169 citations

Yeast ubiquitin-like genes are involved in duplication of the microtubule organizing center.

1996 • 165 citations

HHR23B, a Human Rad23 Homolog, Stimulates XPC Protein in Nucleotide Excision Repair In Vitro

1996 • 164 citations

The glucocorticoid receptor type II complex is a target of the HIV-1 vpr gene product.

1995 • 163 citations

The human immunodeficiency virus type 2 vpr gene is essential for productive infection of human macrophages.

1990 • 159 citations

Biochemical mechanism of HIV-I Vpr function. Specific interaction with a cellular protein.

1994 • 131 citations

Uracil DNA glycosylase specifically interacts with Vpr of both human immunodeficiency virus type 1 and simian immunodeficiency virus of sooty mangabeys, but binding does not correlate with cell cycle arrest

1997 • 120 citations

XPC and human homologs of RAD23: intracellular localization and relationship to other nucleotide excision repair complexes

1996 • 117 citations

Requirement of the Pr55gag precursor for incorporation of the Vpr product into human immunodeficiency virus type 1 viral particles

1994 • 113 citations

Conservation and host specificity of Vpr-mediated cell cycle arrest suggest a fundamental role in primate lentivirus evolution and biology

1997 • 102 citations

Human immunodeficiency virus type 1 Vpr interacts with HHR23A, a cellular protein implicated in nucleotide excision DNA repair

1997 • 94 citations

AIDS: Etiology, Diagnosis, Treatment, and Prevention

1997 • 86 citations

Yeast DNA Repair Protein RAD23 Promotes Complex Formation between Transcription Factor TFIIH and DNA Damage Recognition Factor RAD14

1995 • 83 citations

The RAD7, RAD16, and RAD23 Genes of Saccharomyces cerevisiae: Requirement for Transcription-Independent Nucleotide Excision Repair In Vitro and Interactions between the Gene Products

1997 • 81 citations

HIV accessory proteins as therapeutic targets

1997 • 80 citations

Human immunodeficiency virus type 1 vpr gene induces phenotypic effects similar to those of the DNA alkylating agent, nitrogen mustard

1997 • 80 citations

Transcript levels of theSaccharomyes cerevisiaeDNA repair geneRAD23increase in response to UV light andin meiosis but remain constant in the mitotic cell cycle

1990 • 64 citations

Cloning, Comparative Mapping, and RNA Expression of the Mouse Homologues of theSaccharomyces cerevisiaeNucleotide Excision Repair GeneRAD23

1996 • 62 citations

Rad23 Is Required for Transcription-Coupled Repair and Efficient Overall Repair in Saccharomyces cerevisiae

1996 • 61 citations

DNA cloning 2: Expression systems. A practical approach

1996 • 45 citations

Particle assembly and Vpr expression in human immunodeficiency virus type 1-infected cells demonstrated by immunoelectron microscopy

1994 • 31 citations

Deleted Work

1955 • 0 citations