Identification of the Nef-associated kinase as p21-activated kinase 2

Caspases: the executioners of apoptosis

1997 • 4,674 citations

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

1991 • 1,613 citations

Absence of Intact nef Sequences in a Long-Term Survivor with Nonprogressive HIV-1 Infection

1995 • 1,008 citations

Membrane and Morphological Changes in Apoptotic Cells Regulated by Caspase-Mediated Activation of PAK2

1997 • 742 citations

Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4.

1995 • 557 citations

Interaction of the Nck Adapter Protein with p21-activated Kinase (PAK1)

1996 • 309 citations

Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck

1997 • 259 citations

The p21Rac/Cdc42-activated kinases (PAKs)

1998 • 190 citations

Human immunodeficiency virus type 1 Nef associates with a member of the p21-activated kinase family

1996 • 154 citations

Activation of PAK by HIV and SIV Nef: importance for AIDS in rhesus macaques

1996 • 142 citations

CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1

1996 • 137 citations

Multisite Autophosphorylation of p21-activated Protein Kinase γ-PAK as a Function of Activation

1999 • 114 citations

SH3-Domain Binding Function of HIV-1 Nef Is Required for Association with a PAK-Related Kinase

1998 • 102 citations

Immunological variation and immunohistochemical localization of HIV-1 Nef demonstrated with monoclonal antibodies

1992 • 52 citations

Nef and the Nef-associated kinase

1997 • 18 citations