Checkpoints: Controls That Ensure the Order of Cell Cycle Events

The Molecular Genetics of Cancer

1987 • 1,729 citations

Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli

1984 • 1,608 citations

The SOS regulatory system of Escherichia coli

1982 • 1,491 citations

The RAD9 Gene Controls the Cell Cycle Response to DNA Damage in Saccharomyces cerevisiae

1988 • 1,174 citations

The molecular biology of the yeast saccharomyces

1982 • 1,165 citations

The Chromosomal Basis of Human Neoplasia

1983 • 1,121 citations

Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog

1987 • 1,004 citations

Radiosensitivity in ataxia-telangiectasia: a new explanation.

1980 • 784 citations

Dominoes and Clocks: the Union of Two Views of the Cell Cycle

1989 • 750 citations

DNA topoisomerase II is required at the time of mitosis in yeast

1985 • 747 citations

A role for the nuclear envelope in controlling DNA replication within the cell cycle

1988 • 605 citations

Mini-F plasmid genes that couple host cell division to plasmid proliferation.

1983 • 544 citations

Growth in cell length in the fission yeast Schizosaccharomyces pombe

1985 • 466 citations

A glimpse at chromosomal order

1987 • 423 citations

Duplication of Spindle Plaques and Integration of the Yeast Cell Cycle

1974 • 419 citations

Parameters controlling transcriptional activation during early drosophila development

1986 • 377 citations

Diverse effects of beta-tubulin mutations on microtubule formation and function.

1988 • 373 citations

KAR1, a gene required for function of both intranuclear and extranuclear microtubules in yeast

1987 • 372 citations

S Phase of the Cell Cycle

1989 • 366 citations

A cytoplasmic clock with the same period as the division cycle in Xenopus eggs.

1980 • 358 citations

THE NUCLEUS: STRUCTURE, FUNCTION, AND DYNAMICS

1987 • 333 citations

Caffeine-Induced Uncoupling of Mitosis from the Completion of DNA Replication in Mammalian Cells

1986 • 328 citations

Yeast gene required for spindle pole body duplication: homology of its product with Ca2+-binding proteins.

1986 • 321 citations

The Consequences of Chromosome Imbalance

1986 • 314 citations

The events of the midblastula transition in Xenopus are regulated by changes in the cell cycle

1987 • 312 citations

Mechanism by which caffeine potentiates lethality of nitrogen mustard.

1982 • 294 citations

Centriole cycle in Chinese hamster ovary cells as determined by whole-mount electron microscopy.

1981 • 271 citations

The Chromosome Cycle and the Centrosome Cycle in the Mitotic Cycle

1987 • 263 citations

Saccharomyces cerevisiae cell cycle mutant cdc9 is defective in DNA ligase

1978 • 260 citations

Form-determining function of the genes required for the assembly of the head of bacteriophage T4

1970 • 260 citations

Yeast chromosome replication and segregation

1988 • 250 citations

Spindle formation and chromatin condensation in cells blocked at interphase by mutation of a negative cell cycle control gene

1988 • 235 citations

Virus Structure and Assembly

1985 • 232 citations

MECHANISMS OF X-CHROMOSOME REGULATION

1988 • 222 citations

Nuclear and cytoplasmic mitotic cycles continue in Drosophila embryos in which DNA synthesis is inhibited with aphidicolin.

1988 • 222 citations

Genetic control of the cell division cycle in yeast

1971 • 214 citations

Microtubule Dynamics and Kinetochore Function in Mitosis

1988 • 208 citations

Aneuploidy: Etiology and mechanisms

1987 • 204 citations

The dissociation of nuclear and centrosomal division in gnu, a mutation causing giant nuclei in Drosophila

1986 • 186 citations

Formation of nascent DNA molecules during inhibition of replicon initiation in mammalian cells

1976 • 173 citations

Histone H2B repression causes cell-cycle-specific arrest in yeast: Effects on chromosomal segregation, replication, and transcription

1987 • 164 citations

The Action of Caffeine on X-Irradiated HeLa Cells: III. Enhancement of X-Ray-Induced Killing during G 2 Arrest

1978 • 160 citations

DNA polymerase III, a second essential DNA polymerase, is encoded by the S. cerevisiae CDC2 gene

1989 • 154 citations

A yeast gene essential for regulation of spindle pole duplication.

1988 • 137 citations

Cloning and sequence analysis of the Saccharomyces cerevisiae RAD9 gene and further evidence that its product is required for cell cycle arrest induced by DNA damage.

1989 • 134 citations

A gene required for the separation of chromosomes on the spindle apparatus in yeast

1986 • 130 citations

DNA replication.

1988 • 130 citations

Radiation Effects on DNA Chain Growth in Mammalian Cells

1974 • 128 citations

INDEPENDENCE OF CENTRIOLE FORMATION AND DNA SYNTHESIS

1973 • 125 citations

daughterless-abo-like, a Drosophila maternal-effect mutation that exhibits abnormal centrosome separation during the late blastoderm divisions

1990 • 119 citations

An investigation of the capacity for cleavage and differentiation in Rana pipiens eggs lacking “functional” chromosomes

1951 • 116 citations

Chromosome error propagation and cancer

1989 • 114 citations

Cine-micrographic studies on mitosis in endosperm

1955 • 114 citations

SOS-independent coupling between DNA replication and cell division in Escherichia coli

1986 • 112 citations

The reproduction of centrosomes: nuclear versus cytoplasmic controls.

1986 • 109 citations

Temperature-sensitive mutations in the yeast DNA polymerase I gene.

1987 • 108 citations

Drastic G 2 Arrest in Mammalian Cells after Irradiation with Heavy-Ion Beams

1979 • 108 citations

The Structure of Sister Minichromosome DNA Before Anaphase in Saccharomyces Cerevisiae

1987 • 104 citations

Restricted number of chromosomal regions implicated in aetiology of human cancer and leukaemia

1984 • 102 citations

Direct cell lineage analysis in Drosophila melanogaster by time-lapse, three-dimensional optical microscopy of living embryos.

1989 • 102 citations

Ultraviolet-Microbeam Irradiation of Newt-Cell Cytoplasm: Spindle Destruction, False Anaphase, and Delay of True Anaphase

1970 • 99 citations

The effects of cold and colchicine on mitosis in the newt

1943 • 80 citations

Control of cell-cycle timing in early embryos of Caenorhabditis elegans

1985 • 74 citations

Cytogenetics of Bloom's syndrome

1986 • 70 citations

The synthesis of protein(S) for chromosome condensation may be regulated by a post‐transcriptional mechanism

1981 • 64 citations

Studies of mammalian chromosome replication

1981 • 52 citations

SOME EFFECTS OF X-RADIATION ON THE NEUROBLAST CHROMOSOMES OF THE GRASSHOPPER, CHORTOPHAGA VIRIDIFASCIATA

1938 • 51 citations

An improved assay for DNA ligase reveals temperature-sensitive activity in cdc9 mutants of Saccharomyces cerevisiae

1985 • 46 citations

X-Ray-Induced Division Delay of Individual Yeast Cells

1956 • 46 citations

Localization of Inhibition of replicon initiation to damaged regions of DNA

1977 • 45 citations

Production of cells without deoxyribonucleic acid during thymidine starvation of lexA- cultures of Escherichia coli K-12

1975 • 40 citations

Dosage compensation in Drosophila

1986 • 38 citations

Molecular and Cell Biology of Yeasts

1992 • 30 citations

Mitotic delay and repair in human lymphocytes

1983 • 26 citations

Further studies on a mutant mammalian cell line defective in mitosis

1976 • 25 citations

Cytologische Untersuchung der Embryonalentwicklung von Drosophila Melanogaster Nach Röntgenbestrahlung in Frühen Entwicklungsstadien

2009 • 22 citations

In vitro phenotype of ataxia-telangiectasia (AT) fibroblast strains: clues to the nature of the "AT DNA lesion" and the molecular defect in AT.

1985 • 22 citations

Synthesis of a trans-Acting Inhibitor of DNA Maturation by Prohead Mutants of Phage Λ

1987 • 20 citations

Cytologische Untersuchung der Embryonalentwicklung vonDrosophila MelanogasterNach Röntgenbestrahlung in Frühen Entwicklungsstadien

1966 • 15 citations

Altered DNA synthesis in irradiated and unirradiated ataxia-telangiectasia cells.

1985 • 15 citations

Effects of aphidicolin on premature condensation of sperm chromosomes in fertilized sea urchin eggs

1985 • 7 citations