TRANSCRIPTIONAL REGULATION OF T LYMPHOCYTE DEVELOPMENT AND FUNCTION

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

Functional diversity of helper T lymphocytes

1996 • 4,512 citations

TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function

1997 • 2,571 citations

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

1989 • 2,486 citations

The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells

1997 • 2,317 citations

Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow

1997 • 2,205 citations

Signal transduction by lymphocyte antigen receptors

1994 • 2,145 citations

Structure, Regulation and Function of NF-kappaB

1994 • 2,110 citations

Phosphorylated CREB binds specifically to the nuclear protein CBP

1993 • 2,039 citations

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

1995 • 1,849 citations

TRANSCRIPTIONAL RESPONSES TO POLYPEPTIDE LIGANDS: The JAK-STAT Pathway

1995 • 1,826 citations

JAKS AND STATS: Biological Implications

1998 • 1,788 citations

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.

1995 • 1,739 citations

Stat6 Is Required for Mediating Responses to IL-4 and for the Development of Th2 Cells

1996 • 1,618 citations

Acquisition of Lymphokine-Producing Phenotype by CD4+ T Cells

1994 • 1,573 citations

Essential role of Stat6 in IL-4 signalling

1996 • 1,563 citations

Requirement of Transcription Factor PU.1 in the Development of Multiple Hematopoietic Lineages

1994 • 1,506 citations

INDUCTION OF TH1 AND TH2 CD4⁺T CELL RESPONSES:The Alternative Approaches

1997 • 1,464 citations

Nuclear protein CBP is a coactivator for the transcription factor CREB

1994 • 1,447 citations

Control of IκB-α Proteolysis by Site-Specific, Signal-Induced Phosphorylation

1995 • 1,443 citations

An early haematopoietic defect in mice lacking the transcription factor GATA-2

1994 • 1,412 citations

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

1991 • 1,321 citations

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene

1996 • 1,304 citations

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

1990 • 1,300 citations

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

1996 • 1,277 citations

NF-κB: A lesson in family values

1995 • 1,266 citations

Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses

1995 • 1,184 citations

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

1996 • 1,182 citations

Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.

1997 • 1,138 citations

Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB

1993 • 1,129 citations

Contingent Genetic Regulatory Events in T Lymphocyte Activation

1989 • 1,108 citations

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

1991 • 1,054 citations

Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation.

1993 • 1,047 citations

GATA4 transcription factor is required for ventral morphogenesis and heart tube formation.

1997 • 1,031 citations

Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli.

1995 • 1,010 citations

The ikaros gene is required for the development of all lymphoid lineages

1994 • 976 citations

Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice.

1994 • 969 citations

Identification of a Putative Regulator of Early T Cell Activation Genes

1988 • 933 citations

Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells

1989 • 931 citations

A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence

1989 • 914 citations

Differential Requirements for Survival and Proliferation of CD8 Naïve or Memory T Cells

1997 • 875 citations

Signals and signs for lymphocyte responses

1994 • 868 citations

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

1992 • 865 citations

T CELL MEMORY

1998 • 863 citations

An Interleukin-4-Induced Transcription Factor: IL-4 Stat

1994 • 856 citations

Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family

1995 • 810 citations

Expression of relB is required for the development of thymic medulla and dendritic cells

1995 • 794 citations

IκB-β regulates the persistent response in a biphasic activation of NF-κB

1995 • 780 citations

Cyclic AMP-Responsive DNA-Binding Protein: Structure Based on a Cloned Placental cDNA

1988 • 772 citations

The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun

1993 • 769 citations

Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1.

1996 • 763 citations

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression.

1995 • 740 citations

Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB

1994 • 732 citations

Mapping of the Inducible IκB Phosphorylation Sites That Signal Its Ubiquitination and Degradation†

1996 • 717 citations

Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart.

1993 • 708 citations

A Novel, Erythroid Cell-Specific Murine Transcription Factor that Binds to the CACCC Element and is Related to the Krüppel Family of Nuclear Proteins†

1993 • 703 citations

T CELL ANTIGEN RECEPTOR SIGNAL TRANSDUCTION PATHWAYS

1996 • 692 citations

The Proto-Oncogene c-maf Is Responsible for Tissue-Specific Expression of Interleukin-4

1996 • 677 citations

Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4.

1995 • 675 citations

Transcription Factor GATA-3 Is Differentially Expressed in Murine Th1 and Th2 Cells and Controls Th2-specific Expression of the Interleukin-5 Gene

1997 • 666 citations

Identification and Characterization of a Gene Encoding a Gut-enriched Krüppel-like Factor Expressed during Growth Arrest

1996 • 647 citations

Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha.

1993 • 639 citations

Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum

1998 • 639 citations

Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development

1993 • 638 citations

SIGNAL TRANSMISSION BETWEEN THE PLASMA MEMBRANE AND NUCLEUS OF T LYMPHOCYTES

1994 • 634 citations

DNA-Binding Specificity of GATA Family Transcription Factors

1993 • 629 citations

LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]

1991 • 627 citations

Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF

1995 • 620 citations

Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis

1995 • 619 citations

Selective Defects in the Development of the Fetal and Adult Lymphoid System in Mice with an Ikaros Null Mutation

1996 • 619 citations

Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

1994 • 618 citations

Transcription factor GATA-3 is required for development of the T-cell lineage

1996 • 614 citations

The transcriptional control of hematopoiesis [see comments]

1996 • 608 citations

The erythroid-specific transcription factor eryf1: A new finger protein

1989 • 608 citations

Positive Selection of Thymocytes

1995 • 604 citations

The transcription factor NF-ATc is essential for cardiac valve formation

1998 • 580 citations

Structural basis for DNA bending by the architectural transcription factor LEF-1

1995 • 574 citations

NF-AT components define a family of transcription factors targeted in T-cell activation

1994 • 573 citations

Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene

1995 • 572 citations

GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut.

1994 • 567 citations

DNA-Binding Specificities of the GATA Transcription Factor Family

1993 • 553 citations

Identification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG box.

1991 • 545 citations

A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma

1995 • 530 citations

The Role of Protein Tyrosine Kinases and Protein Tyrosine Phosphatases in T Cell Antigen Receptor Signal Transduction

1994 • 519 citations

An HMG-box-containing T-cell factor required for thymocyte differentiation

1995 • 518 citations

A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.

1989 • 517 citations

Selection of Optimal κB/Rel DNA-Binding Motifs: Interaction of Both Subunits of NF-κB with DNA Is Required for Transcriptional Activation

1992 • 501 citations

Selective Events in T Cell Development

1994 • 486 citations

Early T Lymphocyte Progenitors

1996 • 473 citations

GATA-6: A Zinc Finger Transcription Factor That Is Expressed in Multiple Cell Lineages Derived from Lateral Mesoderm

1996 • 469 citations

Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4

1996 • 464 citations

A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins.

1993 • 464 citations

A putative second cell-derived oncogene of the avian leukaemia retrovirus E26

1983 • 462 citations

Ikaros, an Early Lymphoid-Specific Transcription Factor and a Putative Mediator for T Cell Commitment

1992 • 458 citations

Hyperproliferation and Dysregulation ofIL-4 Expression in NF-ATp-Deficient Mice

1996 • 456 citations

Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes.

1995 • 446 citations

NF-κB and Rel Proteins in Innate Immunity

1995 • 435 citations

Tripartite structure of the avian erythroblastosis virus E26 transforming gene

1983 • 430 citations

The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins.

1994 • 424 citations

Maf nuclear oncoprotein recognizes sequences related to an AP-1 site and forms heterodimers with both Fos and Jun.

1994 • 418 citations

Isolation of the Cyclosporin-Sensitive T Cell Transcription Factor NFATp

1993 • 415 citations

Structural homology of the product of the Drosophila Krüppel gene with Xenopus transcription factor IIIA

1986 • 406 citations

Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences.

1988 • 404 citations

Stat3 and Stat4: members of the family of signal transducers and activators of transcription.

1994 • 396 citations

MINIREVIEW: Cyclic AMP Response Element Binding Proteins: A Cornucopia of Transcription Factors

1990 • 394 citations

RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development.

1993 • 393 citations

DNA-binding specificity of GATA family transcription factors.

1993 • 392 citations

Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins

1995 • 383 citations

Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development.

1996 • 379 citations

An Enhanced Immune Response in Mice Lacking the Transcription Factor NFAT1

1996 • 375 citations

A thymus-specific member of the HMG protein family regulates the human T cell receptor C alpha enhancer.

1991 • 372 citations

The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryogenesis

1997 • 365 citations

Human GATA-3: a lineage-restricted transcription factor that regulates the expression of the T cell receptor alpha gene.

1991 • 364 citations

DNA-binding specificities of the GATA transcription factor family.

1993 • 363 citations

STRUCTURE AND FUNCTION OF THE PRE-T CELL RECEPTOR

1997 • 362 citations

Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation

1997 • 360 citations

Requirement for IRF-1 in the microenvironment supporting development of natural killer cells

1998 • 352 citations

The Ets-1 Transcription Factor Is Required for the Development of Natural Killer Cells in Mice

1998 • 351 citations

Immunosuppressive drugs prevent a rapid dephosphorylation of transcription factor NFAT1 in stimulated immune cells.

1995 • 347 citations

Characterization of the nuclear and cytoplasmic components of the lymphoid-specific nuclear factor of activated T cells (NF-AT) complex.

1993 • 344 citations

Differential Regulation of Murine T Lymphocyte Subsets

1993 • 343 citations

Sox-4, an Sry-like HMG box protein, is a transcriptional activator in lymphocytes.

1993 • 340 citations

The Transcription Factor NF-ATc1 Regulates Lymphocyte Proliferation and Th2 Cytokine Production

1998 • 340 citations

Redundant Regulation of T Cell Differentiation and TCRα Gene Expression by the Transcription Factors LEF-1 and TCF-1

1998 • 337 citations

Defective activation and survival of T cells lacking the Ets-1 transcription factor

1995 • 329 citations

Cloning of Murine Stat6 and Human Stat6, Stat Proteins That Are Tyrosine Phosphorylated in Responses to IL-4 and IL-3 but Are Not Required for Mitogenesis

1995 • 325 citations

Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer.

1991 • 316 citations

Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene

1995 • 313 citations

A conserved retina-specific gene encodes a basic motif/leucine zipper domain.

1992 • 308 citations

B cells from p50/NF-kappa B knockout mice have selective defects in proliferation, differentiation, germ-line CH transcription, and Ig class switching.

1996 • 304 citations

Delayed Lymphoid Repopulation with Defects in IL-4–Driven Responses Produced by Inactivation of NF-ATc

1998 • 298 citations

NF-κB RelA-deficient Lymphocytes: Normal Development of T Cells and B Cells, Impaired Production of IgA and IgG1 and Reduced Proliferative Responses

1997 • 296 citations

Human transcription factor GATA-2. Evidence for regulation of preproendothelin-1 gene expression in endothelial cells.

1992 • 295 citations

Selection of optimal kappa B/Rel DNA-binding motifs: interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation.

1992 • 286 citations

Identification of a common T/natural killer cell progenitor in human fetal thymus.

1994 • 280 citations

DIFFERENTIAL SIGNALING BY LYMPHOCYTE ANTIGEN RECEPTORS

1997 • 273 citations

v-maf, a viral oncogene that encodes a "leucine zipper" motif.

1989 • 266 citations

A population of early fetal thymocytes expressing FcγRIIIII contains precursors of T lymphocytes and natural killer cells

1992 • 264 citations

THE ROLE OF THE IKAROS GENE IN LYMPHOCYTE DEVELOPMENT AND HOMEOSTASIS

1997 • 262 citations

Base sequence discrimination by zinc-finger DNA-binding domains

1991 • 261 citations

The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf oncogene.

1993 • 260 citations

Isolation of a Gene Encoding a Functional Zinc Finger Protein Homologous to Erythroid Krüppel-Like Factor: Identification of a New Multigene Family

1995 • 260 citations

Novel NFAT Sites That Mediate Activation of the Interleukin-2 Promoter in Response to T-Cell Receptor Stimulation

1995 • 259 citations

Perturbation of the T Lymphocyte Lineage In Transgenic Mice Expressing a Constitutive Repressor of Nuclear Factor (NF)-κB

1997 • 259 citations

Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein

1992 • 258 citations

Cloning of the GATA-binding protein that regulates endothelin-1 gene expression in endothelial cells

1991 • 256 citations

GATA-5: A Transcriptional Activator Expressed in a Novel Temporally and Spatially-Restricted Pattern during Embryonic Development

1997 • 253 citations

GATA-4 is a novel transcription factor expressed in endocardium of the developing heart

1993 • 250 citations

Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB

1996 • 249 citations

Differential expression of the HMG box factors TCF-1 and LEF-1 during murine embryogenesis

1993 • 249 citations

Activation-induced death of mature T cells in the regulation of immune responses

1995 • 248 citations

Die and Let Live: Eliminating Dangerous Lymphocytes

1996 • 242 citations

Molecular genetics of Krüppel, a gene required for segmentation of the Drosophila embryo

1985 • 235 citations

Embryonic expression and cloning of the murine GATA-3 gene

1994 • 233 citations

Isolation and Characterization of the cDNA Encoding BKLF/TEF-2, a Major CACCC-Box-Binding Protein in Erythroid Cells and Selected Other Cells

1996 • 229 citations

The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene.

1994 • 225 citations

Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation.

1994 • 224 citations

Multiple sequence elements of a single functional class are required for cyclic AMP responsiveness of the mouse c-fos promoter.

1989 • 220 citations

MafB, a new Maf family transcription activator that can associate with Maf and Fos but not with Jun.

1994 • 219 citations

NFATx, a Novel Member of the Nuclear Factor of Activated T Cells Family That Is Expressed Predominantly in the Thymus

1995 • 211 citations

cDNA cloning and transcriptional properties of a novel GC box-binding protein, BTEB2

1993 • 203 citations

Failure of Lymphopoiesis after Adoptive Transfer of NF-κB–Deficient Fetal Liver Cells

1997 • 193 citations

Maf and Nrl can bind to AP-1 sites and form heterodimers with Fos and Jun.

1994 • 189 citations

The Transcription Factor Interferon Regulatory Factor 1 (IRF-1) Is Important during the Maturation of Natural Killer 1.1+ T Cell Receptor–α/β+ (NK1+ T) Cells, Natural Killer Cells, and Intestinal Intraepithelial T Cells

1998 • 185 citations

A direct physical association between ETS and AP-1 transcription factors in normal human T cells

1995 • 184 citations

Human EZF, a Krüppel-like Zinc Finger Protein, Is Expressed in Vascular Endothelial Cells and Contains Transcriptional Activation and Repression Domains

1998 • 184 citations

STF-IL-4: a novel IL-4-induced signal transducing factor.

1994 • 183 citations

Regulation of thymocyte development from immature progenitors

1996 • 182 citations

A T-cell specific TCR delta DNA binding protein is a member of the human GATA family.

1991 • 178 citations

Down-Regulation of IL-4 Gene Transcription and Control of Th2 Cell Differentiation by a Mechanism Involving NFAT1

1997 • 176 citations

Defective B cell receptor-mediated responses in mice lacking the Ets protein, Spi-B

1997 • 172 citations

Cyclosporin A suppresses the expression of the interleukin 2 gene by inhibiting the binding of lymphocyte-specific factors to the IL-2 enhancer.

1990 • 171 citations

Protein-kinase-A-dependent activator in transcription factor CREB reveals new role for CREM repressers

1993 • 169 citations

Hematopoiesis: how does it happen?

1995 • 169 citations

NFATc3, a Lymphoid-specific NFATc Family Member That Is Calcium-regulated and Exhibits Distinct DNA Binding Specificity

1995 • 168 citations

Structure-function analysis of the maf oncogene product, a member of the b-Zip protein family

1993 • 161 citations

Two new members of the maf oncogene family, mafK and mafF, encode nuclear b-Zip proteins lacking putative trans-activator domain.

1993 • 154 citations

Multiple protein kinase A-regulated events are required for transcriptional induction by cAMP.

1995 • 148 citations

Cloning of murine TCF-1, a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and T cell receptor alpha enhancers.

1991 • 146 citations

A Similar DNA-binding Motif in NFAT Family Proteins and the Rel Homology Region

1995 • 146 citations

Transcriptional Regulation of T Cell Receptor Genes

1993 • 142 citations

NF-AT-Driven Interleukin-4 Transcription Potentiated by NIP45

1996 • 136 citations

Direct Demonstration of NFATp Dephosphorylation and Nuclear Localization in Activated HT-2 Cells Using a Specific NFATp Polyclonal Antibody

1995 • 134 citations

Expression of ets genes in mouse thymocyte subsets and T cells.

1989 • 128 citations

Developmental switches in the immune system

1994 • 126 citations

The Erythroid Krüppel-Like Factor Transactivation Domain is a Critical Component for Cell-Specific Inducibility of a β-Globin Promoter

1995 • 124 citations

The Role of Ets Transcription Factors in the Development and Function of the Mammalian Immune System

1997 • 121 citations

Mitogenic stimulation of thymocytes results in the calcium-dependent phosphorylation of c-ets-1 proteins.

1988 • 118 citations

Distinct roles for P-CREB and LEF-1 in TCR alpha enhancer assembly and activation on chromatin templates in vitro.

1997 • 117 citations

p50–NF-κB Complexes Partially Compensate for the Absence of RelB: Severely Increased Pathology in p50−/−relB−/−Double-knockout Mice

1997 • 112 citations

Interleukin-4-induced STAT6 Recognizes and Activates a Target Site in the Promoter of the Interleukin-4 Receptor Gene

1996 • 110 citations

Cooperation of binding sites for STAT6 and NF kappa B/rel in the IL-4-induced up-regulation of the human IgE germline promoter.

1997 • 107 citations

Characterization of cis-Regulatory Elements and Nuclear Factors Conferring Th2-Specific Expression of the IL-5 Gene: A Role for a GATA-Binding Protein

1998 • 107 citations

Sox‐4 facilitates thymocyte differentiation

1997 • 105 citations

Expression of GATA‐3 During Lymphocyte Differentiation and Mouse Embryogenesis

1992 • 105 citations

T lymphocyte differentiation in the periphery

1998 • 103 citations

Natural and Engineered Disorders of Lymphocyte Development

1998 • 102 citations

Activity and Expression of Murine Small Maf Family Protein MafK

1995 • 100 citations

The proto-oncogene c-ets is preferentially expressed in lymphoid cells.

1985 • 98 citations

Transcriptional control of lymphoid development: lessons from gene targeting

1996 • 97 citations

Phosphorylation of the Transcription Factor NFATp Inhibits Its DNA Binding Activity in Cyclosporin A-treated Human B and T Cells

1995 • 96 citations

Calcium-induced phosphorylation of ETS1 inhibits its specific DNA binding activity.

1994 • 95 citations

Phosphorylation of CREB by CaM-Kinase IV Activated by CaM-Kinase IV Kinase

1995 • 78 citations

Transcription factors required for lymphoid lineage commitment

1997 • 74 citations

Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development

1993 • 71 citations

Abnormal T lymphocyte development induced by targeted overexpression of IkappaB alpha.

1997 • 70 citations

A Protein Kinase C-, Ras-, and RSK2-dependent Signal Transduction Pathway Activates the cAMP-responsive Element-binding Protein Transcription Factor following T Cell Receptor Engagement

1998 • 63 citations

Regulation of interleukin 4-mediated signaling by naturally occurring dominant negative and attenuated forms of human Stat6

1998 • 63 citations

Expression and induction of nuclear factor-kappa B-related proteins in thymocytes.

1995 • 62 citations

Jak1 Expression Is Required for Mediating Interleukin-4-induced Tyrosine Phosphorylation of Insulin Receptor Substrate and Stat6 Signaling Molecules

1997 • 60 citations

Functional GATA-3 binding sites within murine CD8 alpha upstream regulatory sequences.

1993 • 56 citations

Transcription from a murine T-cell receptor V beta promoter depends on a conserved decamer motif similar to the cyclic AMP response element.

1989 • 48 citations

Transcriptional regulation of T-cell genes during T-cell development

1994 • 48 citations

CREB represses transcription of fos promoter: role of phosphorylation.

1991 • 44 citations

T-cell subset relationships in thymocyte development

1991 • 42 citations

Requirement of an ETS-binding element for transcription of the human lck type I promoter.

1993 • 32 citations

GATA Elements Are Necessary for the Activity and Tissue Specificity of the T-Cell Receptor Beta-Chain Transcriptional Enhancer

1994 • 31 citations

Transcriptional control during T-cell development

1998 • 31 citations

Functional importance of the cyclic AMP response element-like decamer motif in the CD8 alpha promoter.

1993 • 27 citations

CD3 delta enhancer. CREB interferes with the function of a murine CD3-delta A binding factor (M delta AF).

1994 • 16 citations

Nuclear Rel-A and c-Rel protein complexes are differentially distributed within human thymocytes.

1997 • 15 citations

GATA elements are necessary for the activity and tissue specificity of the T-cell receptor beta-chain transcriptional enhancer.

1994 • 15 citations

Tissue distribution of the DNA binding oncoprotein Maf during chicken development.

1995 • 4 citations