Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow

Purification and Characterization of Mouse Hematopoietic Stem Cells

1988 • 2,856 citations

Long-Term Lymphohematopoietic Reconstitution by a Single CD34-Low/Negative Hematopoietic Stem Cell

1996 • 2,160 citations

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow.

1991 • 1,622 citations

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice.

1994 • 1,572 citations

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

1995 • 1,447 citations

Interleukin-2 Receptor γ Chain: a Functional Component of the Interleukin-7 Receptor

1993 • 1,128 citations

The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype

1994 • 1,109 citations

Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain

1995 • 1,024 citations

The ikaros gene is required for the development of all lymphoid lineages

1994 • 976 citations

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

1995 • 881 citations

The aging of hematopoietic stem cells

1996 • 850 citations

Stimulation of B-cell progenitors by cloned murine interleukin-7

1988 • 826 citations

The Biology of Hematopoietic Stem Cells

1995 • 775 citations

Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset

1995 • 687 citations

Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population

1993 • 673 citations

Developing Lymph Nodes Collect CD4 + CD3 − LTβ + Cells That Can Differentiate to APC, NK Cells, and Follicular Cells but Not T or B Cells

1997 • 654 citations

Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation.

1992 • 650 citations

Cytokine dysregulation and acute graft-versus-host disease

1992 • 617 citations

Long-term culture of B lymphocytes and their precursors from murine bone marrow.

1982 • 612 citations

A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells

1990 • 611 citations

The transcriptional control of hematopoiesis [see comments]

1996 • 608 citations

Bcl-2 Rescues T Lymphopoiesis in Interleukin-7 Receptor–Deficient Mice

1997 • 603 citations

Cytokine dysregulation and acute graft-versus-host disease

1992 • 565 citations

Molecular cloning of a ligand for the flt3flk-2 tyrosine kinase receptor: A proliferative factor for primitive hematopoietic cells

1993 • 546 citations

Bcl-2 Can Rescue T Lymphocyte Development in Interleukin-7 Receptor–Deficient Mice but Not in Mutant rag-1 −/− Mice

1997 • 503 citations

Expression and function of the interleukin 7 receptor in murine lymphocytes.

1993 • 496 citations

Early T Lymphocyte Progenitors

1996 • 473 citations

Identification of a lineage of multipotent hematopoietic progenitors

1997 • 466 citations

Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs

1994 • 453 citations

Clonal analysis of hematopoietic stem-cell differentiation in vivo.

1991 • 379 citations

Searching for hematopoietic stem cells: evidence that Thy-1.1lo Lin- Sca-1+ cells are the only stem cells in C57BL/Ka-Thy-1.1 bone marrow.

1992 • 368 citations

Bipotential precursors of B cells and macrophages in murine fetal liver

1992 • 367 citations

A stromal cell line from myeloid long-term bone marrow cultures can support myelopoiesis and B lymphopoiesis.

1987 • 345 citations

CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus

1991 • 343 citations

Functional Participation of the IL-2 Receptor γ Chain in IL-7 Receptor Complexes

1994 • 342 citations

The Earliest T Lineage–Committed Cells Depend on IL-7 for Bcl-2 Expression and Normal Cell Cycle Progression

1997 • 338 citations

Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule

1991 • 331 citations

Isolation of two early B lymphocyte progenitors from mouse marrow: A committed Pre-Pre-B cell and a clonogenic Thy-1lo hematopoietic stem cell

1986 • 330 citations

Identification in culture of a class of hemopoietic colony-forming units with extensive capability to self-renew and generate multipotential hemopoietic colonies.

1982 • 317 citations

Developmental potential of the earliest precursor cells from the adult mouse thymus.

1991 • 294 citations

Modulation of hematopoiesis in mice with a truncated mutant of the interleukin-2 receptor gamma chain

1996 • 268 citations

Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation.

1993 • 233 citations

Interleukin 7 production and function in stromal cell-dependent B cell development.

1989 • 221 citations

Bcl-2 Rescues T Lymphopoiesis, but Not B or NK Cell Development, in Common γ Chain–Deficient Mice

1997 • 220 citations

The interleukin-7 receptor alpha chain transmits distinct signals for proliferation and differentiation during B lymphopoiesis.

1996 • 213 citations

A stochastic model of self‐renewal and commitment to differentiation of the primitive hemopoietic stem cells in culture

1982 • 199 citations

Phenotypic and functional characterization of c-kit expression during intrathymic T cell development.

1992 • 194 citations

Cytokine Receptor Expression on Hematopoietic Stem and Progenitor Cells

1997 • 189 citations

Hemopoietic lineage switch: v-raf oncogene converts Eμmyc transgenic B cells into macrophages

1988 • 179 citations

Clonal proliferation of murine lymphohemopoietic progenitors in culture.

1992 • 163 citations

Rhodamine123 reveals heterogeneity within murine Lin-, Sca-1+ hemopoietic stem cells.

1992 • 160 citations

Differentiation of hematopoietic stem cells in irradiated mouse thymic lobes. Kinetics and phenotype of progeny.

1990 • 148 citations

Identification of a Novel Developmental Stage Marking Lineage Commitment of Progenitor Thymocytes

1997 • 146 citations

Direct evidence for the commitment of hematopoietic stem cells to T, B and myeloid lineages in murine fetal liver

1997 • 144 citations

Clinical and laboratory characteristics of acute leukemia with the 4;11 translocation

1986 • 140 citations

Analysis of differentiation of mouse hemopoietic stem cells in culture by sequential replating of paired progenitors

1984 • 125 citations

Separation and functional analysis of bone marrow cells separated by rhodamine-123 fluorescence.

1987 • 105 citations

Purification of pluripotent hemopoietic stem cells: past and present.

1990 • 102 citations

Thymic stem cells in mouse bone marrow

1994 • 101 citations

Transcriptional control of lymphoid development: lessons from gene targeting

1996 • 97 citations

Negative regulation of early B lymphopoiesis by interleukin 3 and interleukin 1 alpha.

1994 • 88 citations

The same exhaustible multilineage precursor produces both myeloid and lymphoid cells as early as 3-4 weeks after marrow transplantation.

1992 • 79 citations

A stimulatory effect of recombinant murine interleukin-7 (IL-7) on B- cell colony formation and an inhibitory effect of IL-1 alpha

1989 • 78 citations

Severe combined immunodeficiencies.

1992 • 66 citations

The c-kit+ Maturation Pathway in Mouse Thymic T Cell Development: Lineages and Selection

1996 • 56 citations

Frontiers in bone marrow transplantation.

1991 • 50 citations

Negative regulation of early T lymphopoiesis by interleukin-3 and interleukin-1 alpha

1995 • 47 citations

Mouse hematopoietic stem cells and the interaction ofc‐kirreceptor and steel factor

1991 • 40 citations

Simultaneous occurrence of myelomonocytic leukemia and multiple myeloma: Involvement of common leukemic progenitors and their developmental abnormality of “lineage infidelity”

1991 • 38 citations

Stem cells, clonal progenitors, and commitment to the three lymphocyte linages: T, B, and NK Cells

1994 • 26 citations

Molecular basis of adenosine deaminase deficiency.

1994 • 23 citations

B-lymphoid/myeloid stem cell origin in Ph-positive acute leukemia with myeloid markers

1993 • 17 citations