Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.

The Atlas of Mouse Development

1992 • 1,782 citations

An early haematopoietic defect in mice lacking the transcription factor GATA-2

1994 • 1,412 citations

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

1991 • 1,321 citations

Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5.

1995 • 1,130 citations

Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells

1989 • 931 citations

α-lnhibin is a tumour-suppressor gene with gonadal specificity in mice

1992 • 887 citations

GATA-binding transcription factors in hematopoietic cells

1992 • 845 citations

GATA-binding transcription factors in hematopoietic cells

1992 • 727 citations

Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart.

1993 • 708 citations

Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo

1993 • 680 citations

DNA-Binding Specificity of GATA Family Transcription Factors

1993 • 629 citations

Activity and tissue-specific expression of the transcription factor NF-E1 multigene family.

1990 • 629 citations

The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins

1993 • 619 citations

Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis

1995 • 619 citations

A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo.

1993 • 617 citations

Transcription factor GATA-3 is required for development of the T-cell lineage

1996 • 614 citations

The erythroid-specific transcription factor eryf1: A new finger protein

1989 • 608 citations

Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo

1996 • 606 citations

GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut.

1994 • 567 citations

DNA-Binding Specificities of the GATA Transcription Factor Family

1993 • 553 citations

Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos.

1994 • 550 citations

A Subclass of bHLH Proteins Required for Cardiac Morphogenesis

1995 • 544 citations

Molecular Pathways Controlling Heart Development

1996 • 485 citations

Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages

1990 • 481 citations

GATA-6: A Zinc Finger Transcription Factor That Is Expressed in Multiple Cell Lineages Derived from Lateral Mesoderm

1996 • 469 citations

Mutations affecting the cardiovascular system and other internal organs in zebrafish

1996 • 441 citations

Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf 1.

1990 • 422 citations

Death before birth: clues from gene knockouts and mutations

1995 • 373 citations

Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst.

1994 • 372 citations

DNA-binding specificities of the GATA transcription factor family.

1993 • 363 citations

[51] Gene targeting in embryonic stem cells

1993 • 320 citations

Transcription factor GATA-4 regulates cardiac muscle-specific expression of the alpha-myosin heavy-chain gene.

1994 • 310 citations

Localization of transcription factor GATA-4 to regions of the mouse embryo involved in cardiac development

1994 • 299 citations

Human transcription factor GATA-2. Evidence for regulation of preproendothelin-1 gene expression in endothelial cells.

1992 • 295 citations

Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: tetraploid rescue of Hnf-4−/− embryos

1997 • 295 citations

Targeted mutagenesis of the transcription factor GATA-4 gene in mouse embryonic stem cells disrupts visceral endoderm differentiation in vitro

1995 • 275 citations

A hormone-encoding gene identifies a pathway for cardiac but not skeletal muscle gene transcription.

1994 • 271 citations

Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos

1992 • 268 citations

Cloning of the GATA-binding protein that regulates endothelin-1 gene expression in endothelial cells

1991 • 256 citations

GATA-5: A Transcriptional Activator Expressed in a Novel Temporally and Spatially-Restricted Pattern during Embryonic Development

1997 • 253 citations

GATA-4 is a novel transcription factor expressed in endocardium of the developing heart

1993 • 250 citations

Absence of the blood-clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system.

1995 • 235 citations

Embryonic Expression of Lim-1, the Mouse Homolog of Xenopus XLim-1, Suggests a Role in Lateral Mesoderm Differentiation and Neurogenesis

1994 • 215 citations

Sequential expression of HNF-3β and HNF-3α by embryonic organizing centers: the dorsal lip/node, notochord and floor plate

1993 • 189 citations

The GATA-4 transcription factor transactivates the cardiac muscle-specific troponin C promoter-enhancer in nonmuscle cells.

1994 • 186 citations

The development of the myocardium and endocardium in mouse embryos

1992 • 179 citations

Inhibition of Transcription Factor GATA-4 Expression Blocks In Vitro Cardiac Muscle Differentiation

1995 • 175 citations

GATA-binding transcription factors in mast cells regulate the promoter of the mast cell carboxypeptidase A gene.

1991 • 162 citations

Distinct Roles for the Two cGATA-1 Finger Domains

1992 • 159 citations

The C-Terminal Zinc Finger of GATA-1 or GATA-2 Is Sufficient To Induce Megakaryocytic Differentiation of an Early Myeloid Cell Line

1995 • 153 citations

Migration patterns of the precardiac mesoderm in the early chick embryo

1963 • 132 citations

Regulation of rat brain natriuretic peptide transcription. A potential role for GATA-related transcription factors in myocardial cell gene expression.

1994 • 130 citations

A small single-"finger" peptide from the erythroid transcription factor GATA-1 binds specifically to DNA as a zinc or iron complex.

1993 • 128 citations

Over-expression of GATA-6 in Xenopus embryos blocks differentiation of heart precursors

1997 • 112 citations

The effects of a lethal mutation responsible for duplications and twinning in mouse embryos

1949 • 112 citations

Rescue of GATA-1-Deficient Embryonic Stem Cells by Heterologous GATA-Binding Proteins

1995 • 94 citations

A nonerythroid GATA-binding protein is required for function of the human preproendothelin-1 promoter in endothelial cells.

1990 • 89 citations

Polyvinyl alcohol enhances detection of low abundance transcripts in early stage quail embryos in a nonradioactive whole mount in situ hybridization technique.

1994 • 54 citations

Endoderm and Cardiogenesis

1996 • 37 citations

Endodermal movements during foregut formation in the chick embryo

1968 • 27 citations

Relationship between fibronectin expression during gastrulation and heart formation in the rat embryo

1995 • 26 citations