Redundant Regulation of T Cell Differentiation and TCRα Gene Expression by the Transcription Factors LEF-1 and TCF-1

Functional interaction of β-catenin with the transcription factor LEF-1

1996 • 2,847 citations

MyoD or Myf-5 is required for the formation of skeletal muscle

1993 • 1,663 citations

Armadillo Coactivates Transcription Driven by the Product of the Drosophila Segment Polarity Gene dTCF

1997 • 1,201 citations

Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages

1992 • 1,116 citations

Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development

1992 • 973 citations

Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice.

1994 • 969 citations

Profound block in thymocyte development in mice lacking p56lck

1992 • 965 citations

HMG domain proteins: architectural elements in the assembly of nucleoprotein structures

1994 • 813 citations

Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal death

1992 • 700 citations

The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures

1992 • 684 citations

LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]

1991 • 627 citations

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions.

1995 • 546 citations

Identification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG box.

1991 • 545 citations

Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells

1995 • 519 citations

An HMG-box-containing T-cell factor required for thymocyte differentiation

1995 • 518 citations

Control points in early T-cell development

1993 • 429 citations

Analysis and Expression of a Cloned Pre-T Cell Receptor Gene

1994 • 410 citations

A thymus-specific member of the HMG protein family regulates the human T cell receptor C alpha enhancer.

1991 • 372 citations

CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus

1991 • 343 citations

Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation.

1994 • 334 citations

Ancestry and diversity of the HMG box superfamily

1993 • 328 citations

A dominant-negative transgene defines a role for p56lck in thymopoiesis.

1993 • 306 citations

ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function.

1997 • 286 citations

Restoration of early thymocyte differentiation in T-cell receptor beta-chain-deficient mutant mice by transmembrane signaling through CD3 epsilon.

1993 • 214 citations

Extensive Alternative Splicing and Dual Promoter Usage Generate Tcf-1 Protein Isoforms with Differential Transcription Control Properties

1996 • 193 citations

Transcription of T cell receptor beta-chain genes is controlled by a downstream regulatory element.

1988 • 185 citations

LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor-binding sites.

1993 • 161 citations

The hLEF/TCF-1 alpha HMG protein contains a context-dependent transcriptional activation domain that induces the TCR alpha enhancer in T cells.

1993 • 155 citations

Wiring diagrams: regulatory circuits and the control of skeletal myogenesis

1994 • 154 citations

Cloning of murine TCF-1, a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and T cell receptor alpha enhancers.

1991 • 146 citations

Transcriptional Regulation of T Cell Receptor Genes

1993 • 142 citations

Functional dissection of the lck proximal promoter.

1992 • 120 citations

Identification and characterization of a T-cell-specific enhancer adjacent to the murine CD4 gene.

1991 • 116 citations

A locus control region in the T cell receptor α/δ locus

1994 • 109 citations

Functional analysis of the human adenosine deaminase gene thymic regulatory region and its ability to generate position-independent transgene expression.

1992 • 108 citations

A Role for CD81 in Early T Cell Development

1996 • 106 citations

Transcriptional control of lymphoid development: lessons from gene targeting

1996 • 97 citations

T Cell Receptor δ Gene Rearrangement and T Early α (TEA) Expression in Immature αβ LineageThymocytes: Implications for αβ/γδ Lineage Commitment

1996 • 96 citations

Control of γδ T‐Cell Development

1991 • 93 citations

Full reconstitution of the immune deficiency in scid mice with normal stem cells requires low-dose irradiation of the recipients.

1986 • 86 citations

Functional analysis of the murine T-cell receptor beta enhancer and characteristics of its DNA-binding proteins.

1990 • 75 citations

Transcription factors in early T-cell development

1993 • 58 citations

T-lymphocyte development in scid mice is arrested shortly after the initiation of T-cell receptor delta gene recombination.

1991 • 56 citations

Regulation of the human T-cell receptor alpha gene enhancer: multiple ubiquitous and T-cell-specific nuclear proteins interact with four hypomethylated enhancer elements.

1990 • 52 citations

Transcriptional regulation of T-cell genes during T-cell development

1994 • 48 citations

Selectively impaired development of intestinal T cell receptor γδ⁺ cells and liver CD4⁺ NK1⁺ T cell receptor αβ⁺ cells in T cell factor‐1‐deficient mice

1996 • 37 citations

An Enhancer LEF-1/TCF-1 Site is Essential for Insertion Site-Independent Transgene Expression in Thymus

1996 • 21 citations

Identification of a murine homolog of the human adenosine deaminase thymic enhancer

1995 • 16 citations