Transcription from a murine T-cell receptor V beta promoter depends on a conserved decamer motif similar to the cyclic AMP response element.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

1983 • 1,449 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

1983 • 1,418 citations

Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB

1988 • 1,321 citations

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

1988 • 1,256 citations

A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes

1986 • 1,150 citations

A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence

1989 • 914 citations

B Lineage—Specific Interactions of an Immunoglobulin Enhancer with Cellular Factors in Vivo

1985 • 859 citations

Immunoglobulin gene transcription is activated by downstream sequence elements

1983 • 830 citations

The Molecular Genetics of the T-Cell Antigen Receptor and T-Cell Antigen Recognition

1986 • 772 citations

A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes

1986 • 740 citations

12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5'-flanking region.

1987 • 699 citations

Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elements

1984 • 669 citations

Development of the Primary Antibody Repertoire

1987 • 629 citations

Protein-Binding Sites in Ig Gene Enhancers Determine Transcriptional Activity and Inducibility

1987 • 619 citations

Cell-type specificity of iminunoglobulin gene expression is regulated by at least three DNA sequence elements

1985 • 588 citations

Structure of the 5' ends of immunoglobulin genes: a novel conserved sequence.

1984 • 564 citations

The T Cell Receptor

1987 • 554 citations

Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice

1988 • 505 citations

Introduced T cell receptor variable region gene segments recombine in pre-B cells: Evidence that B and T cells use a common recombinase

1986 • 452 citations

Regulation of Genome Rearrangement Events during Lymphocyte Differentiation

1986 • 422 citations

Tissue-specific enhancer of the human glycoprotein hormone alpha-subunit gene: dependence on cyclic AMP-inducible elements.

1987 • 409 citations

Genomic footprinting reveals cell type-specific DNA binding of ubiquitous factors

1987 • 356 citations

Identification of the components of the murine T cell antigen receptor complex

1985 • 333 citations

Transcription cell type specificity is conferred by an immunoglobulin VH gene promoter that includes a functional consensus sequence

1985 • 313 citations

Interaction of cell-type-specific nuclear proteins with immunoglobulin VH promoter region sequences

1986 • 298 citations

A cellular protein, activating transcription factor, activates transcription of multiple E1A-inducible adenovirus early promoters.

1987 • 284 citations

A family of immunologically related transcription factors that includes multiple forms of ATF and AP-1.

1988 • 259 citations

Ontogeny of the T-cell antigen receptor within the thymus

1985 • 250 citations

A cellular transcription factor E4F1 interacts with an E1a-inducible enhancer and mediates constitutive enhancer function in vitro.

1987 • 208 citations

Cyclic AMP and phorbol ester-stimulated transcription mediated by similar DNA elements that bind distinct proteins.

1988 • 198 citations

Identification of factors that interact with the E1A-inducible adenovirus E3 promoter.

1987 • 189 citations

Transcription of T cell receptor beta-chain genes is controlled by a downstream regulatory element.

1988 • 185 citations

A novel, inducible and T cell-specific enhancer located at the 3′ end of the T cell receptor alpha locus.

1989 • 176 citations

Octamer-binding proteins from B or HeLa cells stimulate transcription of the immunoglobulin heavy-chain promoter in vitro.

1988 • 132 citations

Temporal pattern of alcohol dehydrogenase gene transcription reproduced by Drosophila stage-specific embryonic extracts

1988 • 129 citations

Multiple DNA sequence elements are necessary for the function of an immunoglobulin heavy chain promoter.

1987 • 123 citations

A Transcriptional Enhancer 3′ of C _β2 in the T Cell Receptor β Locus

1988 • 118 citations

Tandem linkage and unusual RNA splicing of the T-cell receptor beta-chain variable-region genes.

1987 • 105 citations

Cell-type-specific transcription of an immunoglobulin kappa light chain gene in vitro.

1986 • 96 citations

Complexities of gene regulation by cAMP

1989 • 83 citations

T cell receptor genes in an alloreactive CTL clone: implications for rearrangement and germline diversity of variable gene segments.

1986 • 82 citations

A T cell-specific enhancer is located in a DNase I-hypersensitive area at the 3′ end of the CD3-delta gene.

1988 • 81 citations

Bovine leukemia virus trans-activator p38tax activates heterologous promoters with a common sequence known as a cAMP-responsive element or the binding site of a cellular transcription factor ATF.

1989 • 81 citations

A conserved sequence in the T-cell receptor beta-chain promoter region.

1988 • 74 citations

Tissue-Specific Enhancer of the Human Glycoprotein Hormone α-Subunit Gene: Dependence on Cyclic AMP-Inducible Elements

1987 • 71 citations

Three sequence-specific DNA-protein complexes are formed with the same promoter element essential for expression of the rat somatostatin gene.

1988 • 67 citations

Analysis of a human V beta gene subfamily.

1986 • 63 citations

Complex protein binding within the mouse immunoglobulin heavy-chain enhancer.

1987 • 55 citations

The Molecular Genetics of the T-Cell Antigen Receptor and T-Cell Antigen Recognition

1986 • 54 citations

T cell receptor beta-chain genes in BW5147 and other AKR tumors. Deletion order of murine V beta gene segments and possible 5' regulatory regions.

1988 • 40 citations

Multiple nuclear proteins bind upstream sequences in the promotor region of a T-cell receptor beta-chain variable-region gene: evidence for tissue specificity.

1987 • 31 citations

Isolation and characterization of the gene for the murine T cell differentiation antigen and immunoglobulin-related molecule, Lyt-2

1987 • 22 citations

Lineage-specific expression of a T cell receptor variable gene promoter controlled by upstream sequences.

1989 • 22 citations

An evolutionarily conserved rabbit T-cell receptor ?-chain variable region

1986 • 13 citations

A cluster of rabbit T-cell?-chain variable region genes

1987 • 12 citations