Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation.

Stat3: a STAT Family Member Activated by Tyrosine Phosphorylation in Response to Epidermal Growth Factor and Interleukin-6

1994 • 2,037 citations

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

1993 • 1,223 citations

Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

1994 • 1,015 citations

Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-β gene regulatory elements

1988 • 984 citations

Association and Activation of Jak-Tyk Kinases by CNTF-LIF-OSM-IL-6 β Receptor Components

1994 • 972 citations

A protein tyrosine kinase in the interferon αβ signaling pathway

1992 • 876 citations

Association of Transcription Factor APRF and Protein Kinase Jak1 with the Interleukin-6 Signal Transducer gp130

1994 • 822 citations

A Single Phosphotyrosine Residue of Stat91 Required for Gene Activation by Interferon-γ

1993 • 797 citations

The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction

1993 • 766 citations

Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: Crystal structures of the complexed and peptide-free forms

1993 • 758 citations

Erythroleukemic Differentiation

1978 • 694 citations

Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides

1992 • 684 citations

Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA sequences in chromosomes of Mus musculus

1982 • 611 citations

Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-& gamma; signal transduction pathway

1993 • 548 citations

The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction.

1992 • 530 citations

[35] Epitope tagging and protein surveillance

1991 • 526 citations

Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction.

1993 • 516 citations

JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region.

1994 • 506 citations

Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins

1993 • 504 citations

Development and applications of a molecular genetic linkage map of the mouse genome

1991 • 427 citations

Genetics and Probability in Animal Breeding Experiments

1981 • 425 citations

Interferon-induced nuclear signalling by Jak protein tyrosine kinases

1993 • 374 citations

Tyrosine Phosphorylation of DNA Binding Proteins by Multiple Cytokines

1993 • 367 citations

Ras-Independent Growth Factor Signaling by Transcription Factor Tyrosine Phosphorylation

1993 • 345 citations

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130.

1994 • 304 citations

Linkage, recombination and mapping

1981 • 279 citations

A novel interferon-inducible domain: structural and functional analysis of the human interferon regulatory factor 1 gene promoter.

1993 • 256 citations

Requirement of Tyrosine Phosphorylation for Rapid Activation of a DNA Binding Factor by IL-4

1993 • 256 citations

Leukemia Inhibitory Factor and Interleukin-6 Trigger the Same Immediate Early Response, Including Tyrosine Phosphorylation, upon Induction of Myeloid Leukemia Differentiation

1991 • 186 citations

Inactivation of erythropoietin receptor function by point mutations in a region having homology with other cytokine receptors.

1993 • 174 citations

Loss of erythropoietin responsiveness in erythroid progenitors due to expression of the Evi-1 myeloid-transforming gene.

1993 • 124 citations

Juvenile Spermatogonial Depletion (jsd): A Genetic Defect of Germ Cell Proliferation of Male Mice1

1988 • 101 citations

Selection of lineage-restricted cell lines immortalized at different stages of hematopoietic differentiation from the murine cell line 32D.

1989 • 96 citations

Leukemia inhibitory factor and interleukin-6 trigger the same immediate early response, including tyrosine phosphorylation, upon induction of myeloid leukemia differentiation.

1991 • 95 citations

A Novel Interferon-Inducible Domain: Structural and Functional Analysis of the Human Interferon Regulatory Factor 1 Gene Promoter

1993 • 88 citations

Chromosomal location of murine and human IL-1 receptor genes

1991 • 58 citations

Induction of the granulocyte-macrophage colony-stimulating factor (CSF) receptor by granulocyte CSF increases the differentiative options of a murine hematopoietic progenitor cell.

1990 • 55 citations

Actin mRNAs in HeLa cells

1984 • 46 citations

Inactivation of Erythropoietin Receptor Function by Point Mutations in a Region Having Homology with other Cytokine Receptors

1993 • 45 citations

Novel vectors for expression of cDNA encoding epitope-tagged proteins in mammalian cells

1992 • 33 citations

Loss of sperm in juvenile spermatogonial depletion (jsd) mutant mice is ascribed to a defect of intratubular environment to support germ cell differentiation

1992 • 31 citations

Induction of the Granulocyte-Macrophage Colony-Stimulating Factor (CSF) Receptor by Granulocyte CSF Increases the Differentiative Options of a Murine Hematopoietic Progenitor Cell

1990 • 11 citations