DIFFERENTIAL SIGNALING BY LYMPHOCYTE ANTIGEN RECEPTORS

Inositol trisphosphate and calcium signalling

1993 • 6,546 citations

Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis

1995 • 5,334 citations

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

1994 • 3,285 citations

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1994 • 3,219 citations

SH2 domains recognize specific phosphopeptide sequences

1993 • 2,685 citations

The stress-activated protein kinase subfamily of c-Jun kinases

1994 • 2,616 citations

The Regulation of AP-1 Activity by Mitogen-activated Protein Kinases

1995 • 2,441 citations

Pro-inflammatory Cytokines and Environmental Stress Cause p38 Mitogen-activated Protein Kinase Activation by Dual Phosphorylation on Tyrosine and Threonine

1995 • 2,238 citations

Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor

1996 • 1,946 citations

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis

1996 • 1,784 citations

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1992 • 1,634 citations

Capacitative calcium entry revisited

1990 • 1,499 citations

Transcription Factor ATF2 Regulation by the JNK Signal Transduction Pathway

1995 • 1,453 citations

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

1992 • 1,358 citations

MKK3- and MKK6-Regulated Gene Expression Is Mediated by the p38 Mitogen-Activated Protein Kinase Signal Transduction Pathway

1996 • 1,286 citations

An Osmosensing Signal Transduction Pathway in Yeast

1993 • 1,252 citations

MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo

1993 • 1,169 citations

Serial triggering of many T-cell receptors by a few peptide–MHC complexes

1995 • 1,143 citations

An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G ₁

1995 • 1,142 citations

Contingent Genetic Regulatory Events in T Lymphocyte Activation

1989 • 1,108 citations

Differential Activation of ERK and JNK Mitogen-Activated Protein Kinases by Raf-1 and MEKK

1994 • 1,092 citations

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

1992 • 1,046 citations

ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain

1992 • 1,037 citations

MAP kinase pathways in yeast: For mating and more

1995 • 1,009 citations

Profound block in thymocyte development in mice lacking p56lck

1992 • 965 citations

MAPKs: new JNK expands the group

1994 • 949 citations

Kinetic proofreading in T-cell receptor signal transduction.

1995 • 931 citations

JNK is involved in signal integration during costimulation of T lymphocytes

1994 • 929 citations

An essential role for Rac in Ras transformation

1995 • 895 citations

Controlling Signal Transduction with Synthetic Ligands

1993 • 815 citations

Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene

1993 • 756 citations

Sequential Interactions of the TCR with Two Distinct Cytoplasmic Tyrosine Kinases

1994 • 711 citations

Altered Peptide Ligand–Induced Partial T Cell Activation: Molecular Mechanisms and Role in T Cell Biology

1996 • 698 citations

Evidence that a Single Peptide–MHC Complex on a Target Cell Can Elicit a Cytolytic T Cell Response

1996 • 684 citations

Peripheral Selection of the T Cell Repertoire

1991 • 666 citations

SIGNAL TRANSMISSION BETWEEN THE PLASMA MEMBRANE AND NUCLEUS OF T LYMPHOCYTES

1994 • 634 citations

Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs

1990 • 629 citations

T-cell-receptor affinity and thymocyte positive selection

1996 • 620 citations

Partial T cell signaling: Altered phospho-? and lack of zap70 recruitment in APL-induced T cell anergy

1994 • 608 citations

Raf meets Ras: completing the framework of a signal transduction pathway

1994 • 591 citations

Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast

1995 • 578 citations

NF-AT components define a family of transcription factors targeted in T-cell activation

1994 • 573 citations

Separation of IL-4 Production from Th Cell Proliferation by an Altered T Cell Receptor Ligand

1991 • 565 citations

Essential role for ZAP-70 in both positive and negative selection of thymocytes

1995 • 554 citations

T cell antigen receptor signal transduction: A tale of tails and cytoplasmic protein-tyrosine kinases

1993 • 552 citations

Defective T cell receptor signaling and CD8+ thymic selection in humans lacking Zap-70 kinase

1994 • 552 citations

A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA

1985 • 550 citations

Regulation of T Cell Receptor Signaling by Tyrosine Phosphatase SYP Association with CTLA-4

1996 • 529 citations

Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn

1992 • 514 citations

ζ Phosphorylation Without ZAP-70 Activation Induced by TCR Antagonists or Partial Agonists

1995 • 510 citations

Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation

1989 • 509 citations

Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor

1992 • 501 citations

ZAP-70 Deficiency in an Autosomal Recessive form of Severe Combined Immunodeficiency

1994 • 495 citations

Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway

1990 • 466 citations

Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines.

1989 • 465 citations

Hyperproliferation and Dysregulation ofIL-4 Expression in NF-ATp-Deficient Mice

1996 • 456 citations

Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4 ⁺ T Cells

1996 • 438 citations

The Mitogen-activated Protein Kinase Phosphatases PAC1, MKP-1, and MKP-2 Have Unique Substrate Specificities and Reduced Activity in Vivo toward the ERK2 sevenmaker Mutation

1996 • 434 citations

Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness.

1994 • 431 citations

Activation of T Cells by a Tyrosine Kinase Activation Domain in the Cytoplasmic Tail of CD3 ε

1992 • 430 citations

GENERATION, TRANSLOCATION, AND PRESENTATION OF MHC CLASS I-RESTRICTED PEPTIDES

1995 • 428 citations

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav

1995 • 411 citations

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

1995 • 401 citations

Selective requirement for MAP kinase activation in thymocyte differentiation

1995 • 398 citations

Regulation of T cell receptor signaling by a src family protein-tyrosine kinase (p59fyn)

1991 • 395 citations

Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection

1995 • 394 citations

Cellular immunity to HIV activated by CD4 fused to T cell or Fc receptor polypeptides

1991 • 391 citations

Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor

1986 • 387 citations

Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42.

1995 • 386 citations

Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins

1995 • 383 citations

CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation.

1996 • 382 citations

Blocked Ras Activation in Anergic CD4 ⁺ T Cells

1996 • 380 citations

T cell activation by clustered tyrosine kinases

1993 • 379 citations

Antigen-induced B-cell death and elimination during germinal-centre immune responses

1995 • 377 citations

An Enhanced Immune Response in Mice Lacking the Transcription Factor NFAT1

1996 • 375 citations

Identification of a human src homology 2-containing protein-tyrosine-phosphatase: a putative homolog of Drosophila corkscrew.

1992 • 359 citations

Identification of Rap1 as a Target for the Crk SH3 Domain-Binding Guanine Nucleotide-Releasing Factor C3G

1995 • 359 citations

Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function.

1995 • 355 citations

Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor

1995 • 349 citations

Interaction of Shc with the ζ Chain of the T Cell Receptor Upon T Cell Activation

1993 • 343 citations

Molecular Cloning of SLP-76, a 76-kDa Tyrosine Phosphoprotein Associated with Grb2 in T Cells

1995 • 337 citations

Vav and SLP-76 Interact and Functionally Cooperate in IL-2 Gene Activation

1996 • 335 citations

The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early xenopus development

1995 • 330 citations

Essential flexibility in the T-cell recognition of antigen

1996 • 330 citations

Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes.

1996 • 324 citations

Impaired Negative Selection of T Cells in Hodgkin's Disease Antigen CD30–Deficient Mice

1996 • 316 citations

Ras target proteins in eukaryotic cells

1995 • 316 citations

Activation of the Raf-1 kinase cascade by coumermycin-induced dimerization

1996 • 310 citations

A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection

1995 • 305 citations

Calcineurin Binds the Transcription Factor NFAT1 and Reversibly Regulates Its Activity

1996 • 300 citations

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+CDS+thymocytes

1995 • 300 citations

The protein product of the c-cbl protooncogene is the 120-kDa tyrosine-phosphorylated protein in Jurkat cells activated via the T cell antigen receptor.

1994 • 299 citations

T Cell Receptor-MHC Class I Peptide Interactions: Affinity, Kinetics, and Specificity

1994 • 292 citations

PAC-1: a Mitogen-Induced Nuclear Protein Tyrosine Phosphatase

1993 • 289 citations

Kinetic discrimination in T-cell activation.

1996 • 286 citations

Phosphoinositide-specific phospholipase C and mitogenic signaling

1995 • 286 citations

Involvement of p21ras distinguishes positive and negative selection in thymocytes.

1995 • 278 citations

Unimpaired Thymic and Peripheral T Cell Death in Mice Lacking the Nuclear Receptor NGFI-B (Nur77)

1995 • 273 citations

Rho family members: Activators of MAP kinase cascades

1995 • 253 citations

Protein Kinase C-θ Isoenzyme Selective Stimulation of the Transcription Factor Complex AP-1 in T Lymphocytes

1996 • 251 citations

A complex of Grb2 adaptor protein, Sos exchange factor, and a 36-kDa membrane-bound tyrosine phosphoprotein is implicated in ras activation in T cells.

1994 • 246 citations

Intracellular calcium dependence of gene expression in single T lymphocytes.

1994 • 244 citations

Positive and negative selection invoke distinct signaling pathways.

1996 • 234 citations

A Novel Mitogen-activated Protein Kinase Phosphatase. STRUCTURE, EXPRESSION, AND REGULATION

1995 • 233 citations

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42.

1996 • 229 citations

Molecular Cloning of Mitogen-activated Protein/ERK Kinase Kinases (MEKK) 2 and 3

1996 • 227 citations

The Ras signaling pathway in Drosophila

1995 • 226 citations

Phosphorylated immunoreceptor signaling motifs (ITAMs) exhibit unique abilities to bind and activate Lyn and Syk tyrosine kinases.

1995 • 222 citations

Interactions of Cbl with Grb2 and Phosphatidylinositol 3′-Kinase in Activated Jurkat Cells

1995 • 217 citations

Identification by electrospray ionization mass spectrometry of the sites of tyrosine phosphorylation induced in activated Jurkat T cells on the protein tyrosine kinase ZAP-70.

1994 • 215 citations

Inhibition of Ras-Induced DNA Synthesis by Expression of the Phosphatase MKP-1

1994 • 214 citations

Regulation of the Inositol 1,4,5-Trisphosphate Receptor by Tyrosine Phosphorylation

1996 • 212 citations

NFATx, a Novel Member of the Nuclear Factor of Activated T Cells Family That Is Expressed Predominantly in the Thymus

1995 • 211 citations

Regulation of c-Src tyrosine kinase activity by the Src SH2 domain.

1993 • 208 citations

The B-cell antigen receptor complex: structure and signal transduction

1994 • 204 citations

Correlation between Src family member regulation by the protein-tyrosine-phosphatase CD45 and transmembrane signaling through the T-cell receptor.

1993 • 202 citations

A Novel Phosphotyrosine-binding Domain in the N-terminal Transforming Region of Cbl Interacts Directly and Selectively with ZAP-70 in T Cells

1996 • 201 citations

T cells of patients with the Wiskott-Aldrich syndrome have a restricted defect in proliferative responses.

1993 • 197 citations

Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production.

1996 • 194 citations

Thymic selection: a matter of life and death

1992 • 184 citations

Analysis of the Role of Protein Kinase C-α, -ε, and -ζ in T Cell Activation

1995 • 184 citations

GRB2 and Phospholipase C-7γ1 Associate with a 36- to 38-Kilodalton Phosphotyrosine Protein after T-Cell Receptor Stimulation

1994 • 181 citations

Differential effects of expression of the CD45 tyrosine protein phosphatase on the tyrosine phosphorylation of the lck, fyn, and c-src tyrosine protein kinases.

1993 • 179 citations

Characterization of T cell mutants with defects in capacitative calcium entry: genetic evidence for the physiological roles of CRAC channels.

1995 • 179 citations

Crystal Structure of the V _α Domain of a T Cell Antigen Receptor

1995 • 178 citations

Early Signal Transduction by the Antigen Receptor Without Commitment to T Cell Activation

1988 • 169 citations

Multiple p21ras effector pathways regulate nuclear factor of activated T cells.

1996 • 168 citations

NFATc3, a Lymphoid-specific NFATc Family Member That Is Calcium-regulated and Exhibits Distinct DNA Binding Specificity

1995 • 168 citations

Specific interaction of the CD45 protein-tyrosine phosphatase with tyrosine-phosphorylated CD3 zeta chain.

1994 • 163 citations

Induction of Mitogen-activated Protein Kinase Phosphatase 1 by the Stress-activated Protein Kinase Signaling Pathway but Not by Extracellular Signal-regulated Kinase in Fibroblasts

1996 • 162 citations

Tyrosine-phosphorylated T cell receptor ζ chain associates with the actin cytoskeleton upon Activation of mature T lymphocytes

1995 • 162 citations

Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self-reactive T cells.

1996 • 161 citations

The regulation and function of p21ras during T-cell activation and growth

1995 • 160 citations

Cloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase C gamma 1, Grb2, and phosphatidylinositol 3-kinase.

1995 • 158 citations

Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif.

1994 • 158 citations

Identification of HS1 protein as a major substrate of protein-tyrosine kinase(s) upon B-cell antigen receptor-mediated signaling.

1993 • 156 citations

Binding of ZAP-70 to Phosphorylated T-Cell Receptor ζ and η Enhances Its Autophosphorylation and Generates Specific Binding Sites for SH2 Domain-Containing Proteins

1995 • 154 citations

Vertebrate non‐receptor protein–tyrosine kinase families

1996 • 154 citations

A tyrosine-phosphorylated 70-kDa protein binds a photoaffinity analogue of ATP and associates with both the zeta chain and CD3 components of the activated T cell antigen receptor.

1992 • 146 citations

Short related sequences in the cytoplasmic domains of CD4 and CD8 mediate binding to the amino-terminal domain of the p56lck tyrosine protein kinase.

1990 • 145 citations

JNK, but not MAPK, activation is associated with Fas‐mediated apoptosis in human T cells

1996 • 142 citations

The protein tyrosine kinase ZAP-70 can associate with the SH2 domain of proto-Vav.

1994 • 140 citations

p21ras and calcineurin synergize to regulate the nuclear factor of activated T cells.

1993 • 139 citations

Ligands for the T-cell receptor: hard times for avidity models

1995 • 138 citations

Interactions of Cbl with Two Adaptor Proteins, Grb2 and Crk, upon T Cell Activation

1996 • 136 citations

MEK1 and the extracellular signal-regulated kinases are required for the stimulation of IL-2 gene transcription in T cells.

1996 • 135 citations

Direct Demonstration of NFATp Dephosphorylation and Nuclear Localization in Activated HT-2 Cells Using a Specific NFATp Polyclonal Antibody

1995 • 134 citations

Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes.

1996 • 130 citations

The Tyrosine Phosphatase PTP1C Associates with Vav, Grb2, and mSos1 in Hematopoietic Cells

1996 • 124 citations

Anergic T cells are defective in both jun NH2-terminal kinase and mitogen-activated protein kinase signaling pathways.

1996 • 123 citations

Antigen-receptor induced clonal expansion and deletion of lymphocytes are impaired in mice lacking HS1 protein, a substrate of the antigen-receptor-coupled tyrosine kinases.

1995 • 122 citations

Conformational Changes Induced in the Protein Tyrosine Kinase p72^syk by Tyrosine Phosphorylation or by Binding of Phosphorylated Immunoreceptor Tyrosine-Based Activation Motif Peptides

1996 • 121 citations

The Product of the cbl Oncogene Forms Stable Complexes In Vivo with Endogenous Crk in a Tyrosine Phosphorylation-Dependent Manner

1996 • 117 citations

Protein phosphatase 2A positively and negatively regulates Ras1-mediated photoreceptor development in Drosophila.

1996 • 116 citations

lnterleukin-2 transcriptional block by multifunctional Ca2+/ calmodulin kinase

1994 • 115 citations

Evidence for Multiple Activators for Stress-activated Protein Kinases/c-Jun Amino-terminal Kinases.

1995 • 114 citations

Rescue of Signaling by a Chimeric Protein Containing the Cytoplasmic Domain of CD45

1993 • 112 citations

The extracellular domain of CD45 controls association with the CD4-T cell receptor complex and the response to antigen-specific stimulation.

1996 • 111 citations

The truncation that generated the v-cbl oncogene reveals an ability for nuclear transport, DNA binding and acute transformation.

1993 • 109 citations

The catalytic activity of the CD45 membrane-proximal phosphatase domain is required for TCR signaling and regulation.

1994 • 106 citations

Isoforms of the transmembrane tyrosine phosphatase cd45 differentially affect T cell recognition

1994 • 105 citations

GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation.

1994 • 103 citations

The SH2-containing tyrosine phosphatase corkscrew is required during signaling by sevenless, Ras1 and Raf

1996 • 102 citations

Dimerization of soluble major histocompatibility complex-peptide complexes is sufficient for activation of T cell hybridoma and induction of unresponsiveness.

1995 • 101 citations

Transcriptional control of lymphoid development: lessons from gene targeting

1996 • 97 citations

Qualitative and quantitative contributions of the T cell receptor zeta chain to mature T cell apoptosis.

1996 • 94 citations

Modulation of the SH2 Binding Specificity and Kinase Activity of Src by Tyrosine Phosphorylation within Its SH2 Domain

1996 • 91 citations

T Cell Activation-dependent Association between the p85 Subunit of the Phosphatidylinositol 3-Kinase and Grb2/Phospholipase C-γ1-binding Phosphotyrosyl Protein pp36/38

1995 • 90 citations

A Comparison of the Interaction of Shc and the Tyrosine Kinase ZAP-70 with the T Cell Antigen Receptor ζ Chain Tyrosine-based Activation Motif

1995 • 86 citations

Protein Serine/Threonine Kinases of the MAPK Cascade

1995 • 86 citations

T-Cell Antigen Receptor-Induced Signal-Transduction Pathways. Activation and Function of Protein Kinases C in T Lymphocytes

1995 • 83 citations

The Syk/ZAP-70 protein tyrosine kinase connection to antigen receptor signalling processes

1995 • 83 citations

Selective activation of the calcium signaling pathway by altered peptide ligands.

1996 • 83 citations

ADP-ribosylation of the ras-related, GTP-binding protein RhoA inhibits lymphocyte-mediated cytotoxicity.

1992 • 82 citations

LckBP1, a proline-rich protein expressed in haematopoietic lineage cells, directly associates with the SH3 domain of protein tyrosine kinase p56lck.

1995 • 80 citations

Inactivation of the small GTP binding protein Rho induces multinucleate cell formation and apoptosis in murine T lymphoma EL4.

1996 • 79 citations

A signaling pathway governing early thymocyte maturation

1995 • 76 citations

In vivo association of Grb2 with pp116, a substrate of the T cell antigen receptor-activated protein tyrosine kinase.

1994 • 75 citations

Activation of the Mitogen-Activated Protein Kinase Pathway Induces Transcription of the PAC-1 Phosphatase Gene

1996 • 74 citations

Requirement for p56lck tyrosine kinase activation in T cell receptor-mediated thymic selection.

1996 • 74 citations

Specific CD45 isoforms differentially regulate T cell receptor signaling.

1994 • 74 citations

Crk Interacts with Tyrosine-phosphorylated p116 upon T Cell Activation

1995 • 72 citations

Intrathymic signals in thymocytes are mediated by p38 mitogen-activated protein kinase.

1996 • 66 citations

Isolation of mutant T lymphocytes with defects in capacitative calcium entry

1995 • 65 citations

Ras pathways in Caenorhabditis elegans

1995 • 64 citations

Distinct Isoforms of the CD45 Protein-tyrosine Phosphatase Differentially Regulate Interleukin 2 Secretion and Activation Signal Pathways Involving Vav in T Cells

1995 • 64 citations

CD45 Protein-tyrosine Phosphatase Associates with the WW Domain-containing Protein, CD45AP, through the Transmembrane Region

1995 • 64 citations

Activation of p56lck by p72syk through physical association and N-terminal tyrosine phosphorylation.

1994 • 59 citations

The role of Raf-1 in the regulation of extracellular signal-regulated kinase 2 by the T cell antigen receptor.

1994 • 59 citations

Demonstration of a Direct Interaction between p56 and the Cytoplasmic Domain of CD45 in Vitro

1996 • 57 citations

Tyrosine Phosphorylation of Grb2-Associated Proteins Correlates with Phospholipase Cγ1 Activation in T Cells

1996 • 54 citations

Intracellular signaling events during positive and negative selection of CD4+CD8+ thymocytes in vitro.

1995 • 53 citations

Calcium/calmodulin-dependent protein kinase II downregulates both calcineurin and protein kinase C-mediated pathways for cytokine gene transcription in human T cells.

1995 • 48 citations

Structure and function of the T-cell receptor: insights from X-ray crystallography

1996 • 47 citations

The Zinc Finger Transcription Factor EGR-1 Impedes Interleukin-1-Inducible Tumor Growth Arrest

1995 • 41 citations

The aminoterminal phosphotyrosine binding domain of Shc associates with ZAP-70 and mediates TCR dependent gene activation.

1996 • 41 citations

Protein-tyrosine phosphatase activity of CD45 is activated by sequential phosphorylation by two kinases.

1994 • 40 citations

Positive and negative regulation of leukocyte activation by protein tyrosine phosphatases

1995 • 36 citations

The Unique Amino-Terminal Domain of p56^lckRegulates Interactions with Tyrosine Protein Phosphatases in T Lymphocytes

1995 • 35 citations

The role of protein kinase C in the regulation of extracellular signal‐regulated kinase by the T cell antigen receptor

1994 • 34 citations

The role of tyrosine phosphorylation in the interaction of cellular tyrosine kinases with the T cell receptor ζ chain tyrosine‐based activation motif

1995 • 29 citations

Binding of T cell receptor to major histocompatibility complex class II‐peptide complexes at the single‐cell level results in the induction of antigen unresponsiveness (anergy)

1992 • 28 citations

Protein kinase C is not a downstream effector of p21^ras in activated T cells

1995 • 26 citations