NFATc3, a Lymphoid-specific NFATc Family Member That Is Calcium-regulated and Exhibits Distinct DNA Binding Specificity

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1991 • 4,043 citations

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1992 • 1,634 citations

SRα Promoter: an Efficient and Versatile Mammalian cDNA Expression System Composed of the Simian Virus 40 Early Promoter and the R-U5 Segment of Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat

1988 • 1,351 citations

Involvement of a calcineurin/ inhibitor-1 phosphatase cascade in hippocampal long-term depression

1994 • 1,063 citations

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

1991 • 1,054 citations

Identification of a Putative Regulator of Early T Cell Activation Genes

1988 • 933 citations

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

1992 • 865 citations

The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun

1993 • 769 citations

Secreted placental alkaline phosphatase: a powerful new quantitative indicator of gene expression in eukaryotic cells

1988 • 687 citations

Ternary complex factors: growth factor regulated transcriptional activators

1994 • 686 citations

Cyclosporin A Specifically Inhibits Function of Nuclear Proteins Involved in T Cell Activation

1989 • 679 citations

NF-AT components define a family of transcription factors targeted in T-cell activation

1994 • 573 citations

Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate–early gene nur77

1994 • 551 citations

Characterization of antigen receptor response elements within the interleukin-2 enhancer.

1988 • 451 citations

Isolation of the Cyclosporin-Sensitive T Cell Transcription Factor NFATp

1993 • 415 citations

A system of nomenclature for band patterns of mouse chromosomes

1973 • 368 citations

Effects of Cyclosporine A on T Cell Development and Clonal Deletion

1988 • 354 citations

Characterization of the nuclear and cytoplasmic components of the lymphoid-specific nuclear factor of activated T cells (NF-AT) complex.

1993 • 344 citations

Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor.

1990 • 292 citations

Abnormal differentiation of thymocytes in mice treated with cyclosporin A

1988 • 281 citations

Thymocyte Expression of RAG-1 and RAG-2: Termination by T Cell Receptor Cross-Linking

1991 • 270 citations

Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: roles for NF-Y and NF-ATc.

1993 • 245 citations

A differential-avidity model for T-cell selection

1994 • 239 citations

CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection

1993 • 225 citations

The generation of radiolabeled DNA and RNA probes with polymerase chain reaction

1989 • 211 citations

Identification of a novel cyclosporin-sensitive element in the human tumor necrosis factor alpha gene promoter.

1993 • 202 citations

The granulocyte-macrophage colony-stimulating factor/interleukin 3 locus is regulated by an inducible cyclosporin A-sensitive enhancer.

1993 • 201 citations

[31] Secreted placental alkaline phosphatase as a eukaryotic reporter gene

1992 • 176 citations

A common factor regulates both Th1- and Th2-specific cytokine gene expression.

1994 • 151 citations

A Similar DNA-binding Motif in NFAT Family Proteins and the Rel Homology Region

1995 • 146 citations

Cyclosporin A inhibits CD40 ligand expression in T lymphocytes.

1994 • 142 citations

Transcription of the interleukin 4 gene is regulated by multiple promoter elements.

1993 • 103 citations

Cell type specificity and activation requirements for NFAT-1 (nuclear factor of activated T-cells) transcriptional activity determined by a new method using transgenic mice to assay transcriptional activity of an individual nuclear factor.

1990 • 101 citations

Molecular basis for developmental changes in interleukin-2 gene inducibility.

1993 • 96 citations

The Rel family: models for transcriptional regulation and oncogenic transformation

1992 • 80 citations

Gene for lymphoid enhancer-binding factor 1 (LEF1) mapped to human chromosome 4 (q23–q25) and mouse chromosome 3 near Egf

1991 • 56 citations

Nuclear events after activation of CD4+8+ thymocytes.

1990 • 50 citations

Cloning and chromosomal localization of the human and murine genes for the T-cell transcription factors NFATc and NFATp

1995 • 31 citations

A promoter element of the human serine esterase granzyme B gene controls specific transcription in activated T cells

1993 • 30 citations

Structure of the murine CD40 ligand gene

1994 • 29 citations

Characterization of NF(P), the Nuclear Factor That Interacts with the Regulatory P Sequence (5′-CGAAAATTTCC-3′) of the Human Interleukin-4 Gene: Relationship to NF-κB and NF-AT

1994 • 20 citations