Interleukin-7

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1999 • 5,659 citations

Interleukin-10-deficient mice develop chronic enterocolitis

1993 • 4,225 citations

Preferential Localization of Effector Memory Cells in Nonlymphoid Tissue

2001 • 1,922 citations

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene

1991 • 1,783 citations

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

1993 • 1,638 citations

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow.

1991 • 1,622 citations

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

2000 • 1,596 citations

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice.

1994 • 1,572 citations

RAG-1 and RAG-2, Adjacent Genes That Synergistically Activate V(D)J Recombination

1990 • 1,450 citations

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

1995 • 1,447 citations

Protein tyrosine kinase PYK2 involved in Ca2+-induced regulation of ion channel and MAP kinase functions

1995 • 1,367 citations

Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses

1998 • 1,316 citations

Generation and Analysis of Interleukin-4 Deficient Mice

1991 • 1,266 citations

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

1999 • 1,139 citations

Interleukin-2 Receptor γ Chain: a Functional Component of the Interleukin-7 Receptor

1993 • 1,128 citations

Visualizing the generation of memory CD4 T cells in the whole body

2001 • 1,029 citations

Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15.

1994 • 1,008 citations

Identification of a ligand for the c-kit proto-oncogene

1990 • 970 citations

Profound block in thymocyte development in mice lacking p56lck

1992 • 965 citations

IL-7 is critical for homeostatic proliferation and survival of naïve T cells

2001 • 940 citations

Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting

1991 • 892 citations

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

1995 • 881 citations

Cloning of the γ Chain of the Human IL-2 Receptor

1992 • 835 citations

Disruption of the Jak1 Gene Demonstrates Obligatory and Nonredundant Roles of the Jaks in Cytokine-Induced Biologic Responses

1998 • 827 citations

Defective IL7R expression in T-B+NK+ severe combined immunodeficiency

1998 • 805 citations

The IL-2/IL-2 receptor system: A current overview

1993 • 778 citations

The kit ligand: A cell surface molecule altered in steel mutant fibroblasts

1990 • 777 citations

Glucocorticoid Therapy for Immune-Mediated Diseases: Basic and Clinical Correlates

1993 • 762 citations

The role of shared receptor motifs and common stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15

1995 • 760 citations

Sharing of the Interleukin-2 (IL-2) Receptor γ Chain Between Receptors for IL-2 and IL-4

1993 • 734 citations

Defective Lymphoid Development in Mice Lacking Jak3

1995 • 650 citations

Alterations in Signal Transduction Molecules in T Lymphocytes from Tumor-Bearing Mice

1992 • 650 citations

Interaction of IL-2Rβ and γ _c Chains with Jak1 and Jak3: Implications for XSCID and XCID

1994 • 647 citations

Modulation of Epithelial Cell Growth by Intraepithelial γδ T Cells

1994 • 644 citations

Haemopoietic receptors and helical cytokines

1990 • 642 citations

Cloning of the human and murine interleukin-7 receptors: Demonstration of a soluble form and homology to a new receptor superfamily

1990 • 614 citations

Antigen CD34+ marrow cells engraft lethally irradiated baboons.

1988 • 608 citations

Progenitors for Ly-1 B cells are distinct from progenitors for other B cells.

1985 • 599 citations

A critical role of λ5 protein in B cell development

1992 • 583 citations

The Mechanism of V(D)J Joining: Lessons from Molecular, Immunological, and Comparative Analyses

1994 • 579 citations

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

1992 • 574 citations

The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver.

1993 • 573 citations

Defects in B Lymphocyte Maturation and T Lymphocyte Activation in Mice Lacking Jak3

1995 • 551 citations

Human severe combined immunodeficiency: Genetic, phenotypic, and functional diversity in one hundred eight infants

1997 • 543 citations

Cytokine-driven Proliferation and Differentiation of Human Naive, Central Memory, and Effector Memory CD4+ T Cells

2001 • 538 citations

Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis.

1992 • 536 citations

CD8 is needed for development of cytotoxic T but not helper T cells

1991 • 528 citations

Increased production of IL-7 accompanies HIV-1–mediated T-cell depletion: implications for T-cell homeostasis

2001 • 519 citations

Expression and function of the interleukin 7 receptor in murine lymphocytes.

1993 • 496 citations

Developmental defects of lymphoid cells in Jak3 kinase-deficient mice

1995 • 493 citations

IL-7 Enhances the Survival and Maintains the Size of Naive T Cells

2001 • 437 citations

Quantitative detection of immune activation transcripts as a diagnostic tool in kidney transplantation

1997 • 437 citations

Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin

2000 • 435 citations

The Interleukin-2 Receptor γ Chain: Its Role in the Multiple Cytokine Receptor Complexes and T Cell Development in XSCID

1996 • 411 citations

Cloning of the Murine Thymic Stromal Lymphopoietin (Tslp) Receptor

2000 • 405 citations

Increased insulin sensitivity and hypoglycaemia in mice lacking the p85α subunit of phosphoinositide 3–kinase

1999 • 396 citations

Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generation.

1990 • 396 citations

Identification of the Earliest B Lineage Stage in Mouse Bone Marrow

1996 • 395 citations

Tumor Necrosis Factor and Granulocyte Macrophage-Colony Stimulating Factor Stimulate Human Macrophages to Restrict Growth of Virulent Mycobacterium avium and to Kill Avirulent M. avium: Killing Effector Mechanism Depends on the Generation of Reactive Nitrogen Intermediates

1991 • 390 citations

Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors

1999 • 386 citations

Loss of T-cell receptor zeta chain and p56lck in T-cells infiltrating human renal cell carcinoma.

1993 • 385 citations

Cloning and Characterization of Cell Adhesion Kinase β, a Novel Protein-tyrosine Kinase of the Focal Adhesion Kinase Subfamily

1995 • 385 citations

B cell precursor growth-promoting activity. Purification and characterization of a growth factor active on lymphocyte precursors.

1988 • 379 citations

Interleukin 7 is produced by human intestinal epithelial cells and regulates the proliferation of intestinal mucosal lymphocytes.

1995 • 376 citations

Identification and Characterization of a Novel Related Adhesion Focal Tyrosine Kinase (RAFTK) from Megakaryocytes and Brain

1995 • 365 citations

Hydrogen peroxide secreted by tumor‐derived macrophages down‐modulates signal‐transducing zeta molecules and inhibits tumor‐specific T cell‐and natural killer cell‐mediated cytotoxicity

1996 • 364 citations

Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukin 7 monoclonal antibody.

1993 • 345 citations

Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma.

1993 • 344 citations

A thymic stromal cell line supports in vitro development of surface IgM+ B cells and produces a novel growth factor affecting B and T lineage cells.

1994 • 343 citations

Functional Participation of the IL-2 Receptor γ Chain in IL-7 Receptor Complexes

1994 • 342 citations

Interleukin 7 receptor-deficient mice lack gammadelta T cells.

1996 • 316 citations

γ chain required for naïve CD4+ T cell survival but not for antigen proliferation

2000 • 314 citations

Cytokine regulation of neuronal differentiation of hippocampal progenitor cells

1993 • 307 citations

Inhibition of gamma delta T cell development and early thymocyte maturation in IL-7 -/- mice.

1996 • 301 citations

Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSF1R family.

1991 • 300 citations

Interleukin 4 (IL-4) or IL-7 Prevents the Death of Resting T Cells: Stat6 Is Probably Not Required for the Effect of IL-4

1997 • 293 citations

Interleukin-7: master regulator of peripheral T-cell homeostasis?

2001 • 290 citations

IL-7 receptor α+ CD3– cells in the embryonic intestine induces the organizing center of Peyer's patches

1999 • 289 citations

Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells.

1989 • 288 citations

Arrested B Lymphopoiesis and Persistence of Activated B Cells in Adult Interleukin 7−/− Mice

2001 • 271 citations

A developmental switch in B lymphopoiesis.

1991 • 270 citations

In vitro growth of murine T cells. V. The isolation and growth of lymphoid cells infiltrating syngeneic solid tumors.

1980 • 264 citations

Experimental and Clinical Studies of Cytokine Gene-Modified Tumor Cells

1994 • 259 citations

Activation of a Novel Calcium-dependent Protein-tyrosine Kinase

1996 • 256 citations

Cutaneous lymphoproliferation and lymphomas in interleukin 7 transgenic mice.

1993 • 255 citations

Coreceptor Reversal in the Thymus

2000 • 253 citations

Interleukin-7 stimulates osteoclast formation by up-regulating the T-cell production of soluble osteoclastogenic cytokines

2000 • 251 citations

Interleukin 7 induces CD4+ T cell-dependent tumor rejection.

1991 • 245 citations

Trophic effects of interleukin-4, -7 and -8 on hippocampal neuronal cultures: potential involvement of glial-derived factors

1993 • 244 citations

Interleukin-7: physiological roles and mechanisms of action

1999 • 243 citations

Molecular Cloning and Biological Characterization of a Novel Murine Lymphoid Growth Factor

2000 • 232 citations

Interleukin 7 Transgenic Mice Develop Chronic Colitis with Decreased Interleukin 7 Protein Accumulation in the Colonic Mucosa

1998 • 232 citations

Thymic Stromal Lymphopoietin: A Cytokine That Promotes the Development of IgM+ B Cells In Vitro and Signals Via a Novel Mechanism

1999 • 231 citations

IL-7-Dependent Extrathymic Expansion of CD45RA+ T Cells Enables Preservation of a Naive Repertoire

1998 • 230 citations

Normal B cell precursors responsive to recombinant murine IL-7 and inhibition of IL-7 activity by transforming growth factor-beta.

1989 • 229 citations

Development and function of B-1 cells

2000 • 229 citations

Serum levels of IL-7 in bone marrow transplant recipients: relationship to clinical characteristics and lymphocyte count

1999 • 225 citations

The role of recombinant stem cell factor in early B cell development. Synergistic interaction with IL-7.

1991 • 222 citations

Interleukin-7: a Cofactor For V(D)J Rearrangement of the T Cell Receptor β Gene

1993 • 221 citations

Mechanisms of rejection induced by tumor cell-targeted gene transfer of interleukin 2, interleukin 4, interleukin 7, tumor necrosis factor, or interferon gamma.

1993 • 221 citations

Interleukin 7 production and function in stromal cell-dependent B cell development.

1989 • 221 citations

Alterations in the signal‐transducing molecules of T cells and nk cells in colorectal tumor‐infiltrating, gut mucosal and peripheral lymphocytes: Correlation with the stage of the disease

1995 • 217 citations

Alterations in expression and function of signal-transducing proteins in tumor-associated T and natural killer cells in patients with ovarian carcinoma.

1996 • 216 citations

The interleukin-7 receptor alpha chain transmits distinct signals for proliferation and differentiation during B lymphopoiesis.

1996 • 213 citations

Administration of interleukin-7 after allogeneic bone marrow transplantation improves immune reconstitution without aggravating graft-versus-host disease

2001 • 212 citations

Interleukin-7 receptor alpha is essential for the development of gamma delta + T cells, but not natural killer cells.

1996 • 211 citations

Thymic and extrathymic origins of gut intraepithelial lymphocyte populations in mice.

1994 • 208 citations

A single bone marrow-derived stromal cell type supports the in vitro growth of early lymphoid and myeloid cells

1987 • 207 citations

Distinct Roles of the Phosphatidylinositol 3-Kinase and STAT5 Pathways in IL-7-Mediated Development of Human Thymocyte Precursors

1999 • 205 citations

Interleukin 7 is produced by murine and human keratinocytes.

1993 • 198 citations

Thymus Independent T Cell Development and Selection in the Intestinal Epithelium

1994 • 197 citations

Alterations in T cell receptor and signal transduction molecules in melanoma patients.

1995 • 192 citations

Interleukin 7 induces cytokine secretion and tumoricidal activity by human peripheral blood monocytes.

1991 • 187 citations

Purification and characterization of heterogeneous pluripotent hematopoietic stem cell populations expressing high levels of c-kit receptor

1993 • 185 citations

Cloning of human thymic stromal lymphopoietin (TSLP) and signaling mechanisms leading to proliferation

2001 • 185 citations

Identification of a membrane glycoprotein associated with haemopoietic progenitor cells

1985 • 184 citations

The Molecular Basis of X‐Linked Severe Combined Immunodeficiency: The Role of the Interleukin‐2 Receptor γ Chain as a Common γ Chain, γc

1994 • 180 citations

Effect of IL-7 on the growth of fetal thymocytes in culture.

1989 • 179 citations

The IL-7 Receptor Controls the Accessibility of the TCRγ Locus by Stat5 and Histone Acetylation

2001 • 176 citations

Migration and Function of Antigen-Primed Nonpolarized T Lymphocytes in Vivo

2001 • 176 citations

Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction.

1991 • 175 citations

Age-associated thymic atrophy is linked to a decline in IL-7 production

2002 • 174 citations

Human intestinal epithelial cells express functional cytokine receptors sharing the common gamma c chain of the interleukin 2 receptor.

1995 • 174 citations

Enrichment of hematopoietic precursor cells and cloning of multipotential B-lymphocyte precursors.

1985 • 173 citations

Human IL-7: a novel T cell growth factor.

1989 • 172 citations

THE MOLECULAR BASIS OF X-LINKED SEVERE COMBINED IMMUNODEFICIENCY: Defective Cytokine Receptor Signaling

1996 • 168 citations

Immunizing and curative potential of replicating and nonreplicating murine mammary adenocarcinoma cells engineered with interleukin (IL)-2, IL-4, IL-6, IL-7, IL-10, tumor necrosis factor alpha, granulocyte-macrophage colony-stimulating factor, and gamma-interferon gene or admixed with conventional adjuvants.

1994 • 167 citations

Oligoclonality of human intestinal intraepithelial T cells.

1992 • 165 citations

T-cell lineage commitment and cytokine responses of thymic progenitors

1995 • 164 citations

Interleukin-7 restores immunity in athymic T-cell–depleted hosts

2001 • 160 citations

Interleukin 7 enhances cytolytic T lymphocyte generation and induces lymphokine-activated killer cells from human peripheral blood.

1990 • 160 citations

NATURALLY OCCURRING PRIMARY DEFICIENCIES OF THE IMMUNE SYSTEM

1997 • 159 citations

Interleukin-7 is a growth factor of precursor B and T acute lymphoblastic leukemia

1990 • 158 citations

Stromal cell lines which support lymphocyte growth: characterization, sensitivity to radiation and responsiveness to growth factors

1988 • 158 citations

Stepwise progression of B lineage differentiation supported by interleukin 7 and other stromal cell molecules.

1990 • 158 citations

Positive Effects of Glucocorticoids on T Cell Function by Up-Regulation of IL-7 Receptor α

2002 • 158 citations

Murine thymocytes proliferate in direct response to interleukin-7

1989 • 157 citations

Impaired survival and proliferation in IL-7 receptor-deficient peripheral T cells.

1996 • 153 citations

Human intestinal Vdelta1+ lymphocytes recognize tumor cells of epithelial origin.

1996 • 152 citations

Murine interleukin 7 (IL-7) receptor. Characterization on an IL-7-dependent cell line.

1990 • 150 citations

Interleukin 7 independent development of human B cells.

1996 • 147 citations

Immortalization of mouse intestinal epithelial cells by the SV40-large T gene

1993 • 145 citations

IL-7 Administration Alters the CD4:CD8 Ratio, Increases T Cell Numbers, and Increases T Cell Function in the Absence of Activation

2001 • 144 citations

Induction of murine peritoneal gamma/delta T cells and their role in resistance to bacterial infection.

1993 • 144 citations

Enterocyte Expression of Interleukin 7 Induces Development of γδ T Cells and Peyer's Patches

2000 • 143 citations

IL-7 and Not Stem Cell Factor Reverses Both the Increase in Apoptosis and the Decline in Thymopoiesis Seen in Aged Mice

2001 • 143 citations

Circulating Serum Levels of Cytokines and Angiogenic Factors in Patients with Cervical Cancer

1998 • 141 citations

Expression of murine interleukin 7 in a murine glioma cell line results in reduced tumorigenicity in vivo.

1992 • 140 citations

Interleukin 7: effects on early events in lymphopoiesis

1989 • 140 citations

Interleukin-7 in Plasma Correlates with CD4 T-Cell Depletion and May Be Associated with Emergence of Syncytium-Inducing Variants in Human Immunodeficiency Virus Type 1-Positive Individuals

2001 • 136 citations

Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor

1992 • 134 citations

Production of transforming growth factor-beta by Mycobacterium avium-infected human macrophages is associated with unresponsiveness to IFN-gamma.

1993 • 133 citations

Development of B cells in aged mice: decline in the ability of pro-B cells to respond to IL-7 but not to other growth factors.

1997 • 133 citations

Human Recent Thymic Emigrants–Identification, Expansion, And Survival Characteristics

2001 • 133 citations

Crystal structure of recombinant human interleukin-4.

1992 • 132 citations

Interleukin 7 Receptor Control of T Cell Receptor γ Gene Rearrangement: Role of Receptor-associated Chains and Locus Accessibility

1998 • 131 citations

Role of interleukin‐7 in T‐cell development from hematopoietic stem cells

1998 • 130 citations

T lymphocytes need IL-7 but not IL-4 or IL-6 to survive in vivo

2001 • 128 citations

An alternative splice variant of human IL-4, IL-4 delta 2, inhibits IL-4-stimulated T cell proliferation.

1996 • 128 citations

Keratinocyte-derived IL-7 serves as a growth factor for dendritic epidermal T cells in mice.

1993 • 126 citations

Regulation of JAK3 expression in human monocytes: phosphorylation in response to interleukins 2, 4, and 7.

1995 • 126 citations

Interactions between stem cell factor and c-Kit are required for intestinal immune system homeostasis

1994 • 123 citations

Radiosensitivity of thymic interleukin-7 production and thymopoiesis after bone marrow transplantation

2001 • 122 citations

Induction of Germline Transcription in the TCRγ Locus by Stat5

1999 • 120 citations

Different use of T cell receptor transducing modules in two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiation.

1994 • 120 citations

Differential roles of stromal cells, interleukin-7, and kit-ligand in the regulation of B lymphopoiesis

1992 • 120 citations

IL-7 promotes thymocyte proliferation and maintains immunocompetent thymocytes bearing alpha beta or gamma delta T-cell receptors in vitro: synergism with IL-2.

1989 • 119 citations

Induction of TCR Gene Rearrangements in Uncommitted Stem Cells by a Subset of IL-7 Producing, MHC Class II–Expressing Thymic Stromal Cells

1997 • 119 citations

The role of cytokine receptor signaling in lymphocyte development

1999 • 118 citations

Interleukin-7 Receptor Expression on CD8 + T Cells Is Reduced in HIV Infection and Partially Restored With Effective Antiretroviral Therapy

2001 • 118 citations

Knowledge‐based model building of proteins: Concepts and examples

1993 • 116 citations

The acute lymphoblastic leukaemia cell line SEM with t(4;11) chromosomal rearrangement is biphenotypic and responsive to interleukin‐7

1994 • 115 citations

Cytokines and Cell Surface Molecules Independently Induce CXCR4 Expression on CD4+ CCR7+ Human Memory T Cells

2000 • 115 citations

The flt3 ligand promotes the survival of primitive hemopoietic progenitor cells with myeloid as well as B lymphoid potential. Suppression of apoptosis and counteraction by TNF-alpha and TGF-beta.

1996 • 115 citations

The influence of S17 stromal cells and interleukin 7 on B cell development

1990 • 115 citations

Flt3 ligand supports the differentiation of early B cell progenitors in the presence of interleukin‐11 and interleukin‐7

1996 • 115 citations

The hepatocyte growth factor/ met pathway in development, tumorigenesis, and B-cell differentiation

2000 • 112 citations

Interleukin‐7 expression during mouse thymus development

1992 • 112 citations

Expression and activity of signaling molecules in T lymphocytes obtained from patients with metastatic melanoma before and after interleukin 2 therapy.

1996 • 111 citations

TGF-beta down-regulates stromal IL-7 secretion and inhibits proliferation of human B cell precursors.

1997 • 111 citations

Variable expression of CD3‐ζ chain in tumor‐infiltrating lymphocytes (TIL) derived from renal‐cell carcinoma: Relationship with til phenotype and function

1995 • 111 citations

Synergistic effects of IL-7 and IL-12 on human T cell activation.

1995 • 110 citations

IL-7 Receptor and VDJ Recombination: Trophic Versus Mechanistic Actions

1997 • 108 citations

Genetic modification of a murine fibrosarcoma to produce interleukin 7 stimulates host cell infiltration and tumor immunity.

1992 • 105 citations

Changes in the Properties of Gap Junctions during Neuronal Differentiation of Hippocampal Progenitor Cells

1998 • 105 citations

Expression of Cytokine mRNA in Gastric Mucosa withHelicobacter pyloriInfection

1995 • 104 citations

Interleukin 7 generates antitumor cytotoxic T lymphocytes against murine sarcomas with efficacy in cellular adoptive immunotherapy.

1991 • 103 citations

The Interleukin 7 Receptor Is Required for T Cell Receptor γ Locus Accessibility to the V(D)j Recombinase

2000 • 103 citations

IL-7 maintains the T cell precursor potential of CD3-CD4-CD8- thymocytes.

1991 • 100 citations

Isolation in a single step of a highly enriched murine hematopoietic stem cell population with competitive long-term repopulating ability

1989 • 100 citations

Human follicular dendritic cells and vascular cells produce interleukin‐7: a potential role for interleukin‐7 in the germinal center reaction

1996 • 98 citations

Vaccination with IL-7 gene-modified autologous melanoma cells can enhance the anti-melanoma lytic activity in peripheral blood of patients with a good clinical performance status: a clinical phase I study

1998 • 98 citations

A transgenic mouse model to analyze CD8⁺effector T cell differentiationin vivo

1999 • 97 citations

Phenotypic and functional characterization of competitive long-term repopulating hematopoietic stem cells enriched from 5-fluorouracil- treated murine marrow

1993 • 97 citations

IL-7 transgenic mice: analysis of the role of IL-7 in the differentiation of thymocytes in vivo and in vitro

1995 • 95 citations

The expression of the Ig H chain repertoire in developing bone marrow B lineage cells.

1991 • 95 citations

Interleukin-7 or Interleukin-15 Enhances Survival ofMycobacterium tuberculosis-Infected Mice

2000 • 94 citations

Interleukin 7 promotes long-term in vitro growth of antitumor cytotoxic T lymphocytes with immunotherapeutic efficacy in vivo.

1994 • 94 citations

B-1a, B-1b and B-2 B cells display unique VHDJH repertoires formed at different stages of ontogeny and under different selection pressures.

1995 • 93 citations

Expression of the bop gene cluster of Halobacterium halobium is induced by low oxygen tension and by light

1991 • 93 citations

Differentiation of growth signal requirement of B lymphocyte precursor is directed by expression of immunoglobulin.

1991 • 92 citations

Combined signaling through interleukin-7 receptors and flt3 but not c- kit potently and selectively promotes B-cell commitment and differentiation from uncommitted murine bone marrow progenitor cells

1996 • 90 citations

The FLK2/FLT3 ligand synergizes with interleukin-7 in promoting stromal- cell-independent expansion and differentiation of human fetal pro-B cells in vitro

1996 • 90 citations

Administration of recombinant human IL-7 to mice alters the composition of B-lineage cells and T cell subsets, enhances T cell function, and induces regression of established metastases.

1994 • 88 citations

Cytokine production by the bladder carcinoma cell line 5637: rapid analysis of mRNA expression levels using a cDNA-PCR procedure.

1991 • 87 citations

Stimulation of immune reconstitution by interleukin-7 after syngeneic bone marrow transplantation in mice.

1996 • 87 citations

Enrichment and characterization of uncommitted B-cell precursors from fetal liver at day 12 of gestation.

1992 • 86 citations

Interleukin-7 induces N-myc and c-myc expression in normal precursor B lymphocytes.

1992 • 86 citations

Therapeutic Vaccination against Metastatic Carcinoma by Expression-Modulated and Immunomodified Autologous Tumor Cells: A First Clinical Phase I/II Trial

2001 • 86 citations

Tumor cells cotransfected with interleukin‐7 and B7.1 genes induce CD25 and CD28 on tumor‐infiltrating T lymphocytes and are strong vaccines

1995 • 85 citations

Role of bcl-2 in the Development of Lymphoid Cells From the Hematopoietic Stem Cell

1997 • 83 citations

Abnormal signal transduction by T cells of mice with parental tumors is not seen in mice bearing IL-2-secreting tumors.

1994 • 82 citations

IL-7 induces human lymphokine-activated killer cell activity and is regulated by IL-4.

1991 • 82 citations

CD4 is expressed on murine pluripotent hematopoietic stem cells

1992 • 81 citations

The peritoneal Ly‐1 (CD5) B cell repertoire is unique among murine B cell repertoires

1990 • 80 citations

JAK3 protein tyrosine kinase mediates interleukin-7-induced activation of phosphatidylinositol-3' kinase

1995 • 80 citations

Induction of macrophage inflammatory protein-1 beta gene expression in human monocytes by lipopolysaccharide and IL-7.

1991 • 80 citations

Exogenous IL-7 promotes the growth of CD3-CD4-CD8-CD44+CD25+/- precursor cells and blocks the differentiation pathway of TCR-alpha beta cells in fetal thymus organ culture.

1993 • 78 citations

A stimulatory effect of recombinant murine interleukin-7 (IL-7) on B- cell colony formation and an inhibitory effect of IL-1 alpha

1989 • 78 citations

Regulation of human cytotoxic T lymphocyte development by IL-7.

1990 • 78 citations

Gene expression and secretion of cytokines and cytokine receptors from highly purified CD56⁺ natural killer cells stimulated with interleukin‐2, interleukin‐7 and interleukin‐12

1993 • 77 citations

B cell IL-7. Human B cell lines constitutively secrete IL-7 and express IL-7 receptors.

1994 • 77 citations

IL-7 up-regulates HIV-1 replication in naturally infected peripheral blood mononuclear cells.

1996 • 76 citations

Pim-1 levels determine the size of early B lymphoid compartments in bone marrow.

1993 • 74 citations

IFN-gamma-dependent IL-7 gene regulation in keratinocytes.

1995 • 73 citations

Expression and function of the gamma c subunit of the IL-2, IL-4, and IL-7 receptors. Distinct interaction of gamma c in the IL-4 receptor.

1995 • 73 citations

Human Dendritic Cells Express Functional Interleukin-7

1998 • 73 citations

An Essential Role for the IL-7 Receptor During Intrathymic Expansion of the Positively Selected Neonatal T Cell Repertoire

2000 • 73 citations

IL-7 differentially modulates the expression of IFN-gamma and IL-4 in activated human T lymphocytes by transcriptional and post-transcriptional mechanisms.

1996 • 72 citations

Interleukin-7 signaling in human B cell precursor acute lymphoblastic leukemia cells and murine BAF3 cells involves activation of STAT1 and STAT5 mediated via the interleukin-7 receptor alpha chain.

1996 • 72 citations

Interleukin 2 (IL-2) and interleukin 7 (IL-7) reciprocally induce IL-7 and IL-2 receptors on gamma delta T-cell receptor-positive intraepithelial lymphocytes.

1996 • 72 citations

Activation of src family kinases in human pre-B cells by IL-7.

1994 • 71 citations

A critical role of Lyn and Fyn for B cell responses to CD38 ligation and interleukin 5

1997 • 71 citations

The role of IL-7 in thymic and extrathymic development of TCR gamma delta cells.

1998 • 71 citations

Administration of human recombinant IL-7 to normal and irradiated mice increases the numbers of lymphocytes and some immature cells of the myeloid lineage.

1992 • 71 citations

Activation and function of γδ T cells

1994 • 71 citations

Defective T-cell receptor γ gene rearrangement in interleukin-7 receptor knockout mice

1997 • 70 citations

Effects of IL-7 and IL-2 on highly enriched CD56+ natural killer cells. A comparative study.

1991 • 70 citations

Dysregulation of interleukin‐7 receptor may generate loss of cytotoxic T cell response in human immunodeficiency virus type 1 infection

1994 • 70 citations

Age-dependent intestinal lymphoproliferative disorder due to stem cell factor receptor deficiency: parameters in small and large intestine.

1997 • 69 citations

Interleukin 7-induced expression of specific T cell receptor gamma variable region genes in murine fetal liver cultures.

1993 • 69 citations

Constitutive Expression of Interleukin-7 mRNA and Production of IL-7 by a Cloned Murine Thymic Stromal Cell Line

1990 • 68 citations

Regression of intracerebral rat glioma isografts by therapeutic subcutaneous immunization with interferon-γ, interleukin-7, or B7-1-transfected tumor cells

1999 • 68 citations

JAK3 Janus kinase is involved in interleukin 7 signal pathway

1994 • 67 citations

Interleukin 7 (murine pre‐B cell growth factor/lymphopoietin 1) stimulates thymocyte growth: regulation by transforming growth factor beta

1989 • 66 citations

In vivo evaluation of the effects of interleukins 2, 4 and 7 on enhancing the immunotherapeutic efficacy of anti‐tumor cytotoxic T lymphocytes

1991 • 65 citations

Interleukin‐7 (IL‐7) in Colorectal Cancer: IL‐7 is Produced by Tissues from Colorectal Cancer and Promotes Preferential Expansion of Tumour Infiltrating Lymphocytes

1997 • 65 citations

Interleukin 7 receptor engagement stimulates tyrosine phosphorylation, inositol phospholipid turnover, proliferation, and selective differentiation to the CD4 lineage by human fetal thymocytes.

1991 • 65 citations

Involvement of p59fynT in interleukin-5 receptor signaling.

1995 • 65 citations

Putative role for interleukin‐7 in the maintenance of the recirculating naive CD4⁺ T‐cell pool

1999 • 65 citations

Genes for interleukin 7 are transcribed in leukemic cell subsets of individuals with chronic lymphocytic leukemia.

1993 • 65 citations

Pim1 Reconstitutes Thymus Cellularity in Interleukin 7–And Common γ Chain–Mutant Mice and Permits Thymocyte Maturation in Rag- but Not Cd3γ-Deficient Mice

1999 • 63 citations

Characterization of T cell receptors on resident murine dendritic epidermal T cells

1988 • 63 citations

B Lymphocyte development

1990 • 63 citations

Frequent expression of IL-7 gene transcripts in tumor cells of classical Hodgkin's disease.

1995 • 63 citations

Costimulation of cutaneous T-cell lymphoma cells by interleukin-7 and interleukin-2: potential autocrine or paracrine effectors in the Sézary syndrome.

1994 • 62 citations

IL-7 up-regulates the expression of IL-8 from resting and stimulated human blood monocytes.

1992 • 62 citations

Phenotypic and functional analysis of B lymphopoiesis in interleukin‐7‐transgenic mice: expansion of pro/pre‐B cell number and persistence of B lymphocyte development in lymph nodes and spleen

1996 • 62 citations

Elevated circulating interleukin-7 levels in patients with systemic juvenile rheumatoid arthritis.

1995 • 61 citations

Human Small Intestinal Epithelial Cells Secrete Interleukin-7 and Differentially Express Two Different Interleukin-7 mRNA Transcripts: Implications for Extrathymic T-Cell Differentiation

1997 • 61 citations

Characterization of the human and murine IL-7 genes.

1990 • 61 citations

The development of dermatitis infiltrated by γ^δ T cells in IL-7 transgenic mice

1993 • 61 citations

Cytokines in inflammatory malignant fibrous histiocytoma presenting with leukemoid reaction

1993 • 60 citations

Interleukin-7, interleukin-8, soluble TNF receptor, and p53 protein levels are elevated in the serum of patients with Hodgkin's disease

1994 • 58 citations

Induction of murine lymphokine-activated killer cells by recombinant IL-7.

1990 • 58 citations

Characterization of a novel Hodgkin cell line, HD-MyZ, with myelomonocytic features mimicking Hodgkin's disease in severe combined immunodeficient mice.

1993 • 58 citations

T cells from late tumor-bearing mice express normal levels of p56lck, p59fyn, ZAP-70, and CD3 zeta despite suppressed cytolytic activity.

1995 • 57 citations

Administration of recombinant human interleukin-7 to mice induces the exportation of myeloid progenitor cells from the bone marrow to peripheral sites

1994 • 57 citations

IL-7 overexpression in transgenic mouse keratinocytes causes a lymphoproliferative skin disease dominated by intermediate TCR cells: evidence for a hierarchy in IL-7 responsiveness among cutaneous T cells.

1997 • 57 citations

Activity of stem cell factor and IL-7 in combination on normal bone marrow B lineage cells.

1993 • 57 citations

Administration of recombinant human interleukin-7 alters the frequency and number of myeloid progenitor cells in the bone marrow and spleen of mice

1992 • 56 citations

Cytokine regulation of early human lymphopoiesis.

1994 • 56 citations

Heterogeneity of thymic epithelial cells in promoting T-lymphocyte differentiation in vivo.

1991 • 56 citations

Cytokines and bullous pemphigoid.

1999 • 56 citations

Cutting Edge: Histone Acetylation and Recombination at the TCRγ Locus Follows IL-7 Induction

2001 • 54 citations

IL-7 stimulates protective immunity in mice against the intracellular pathogen, Toxoplasma gondii.

1995 • 54 citations

Il-7 supports D-J but not V-DJ rearrangement of TCR-beta gene in fetal liver progenitor cells.

1996 • 53 citations

Flow Cytometric Analysis of Normal B Lymphoid Development

1988 • 53 citations

Distinct Roles for Signals Relayed through the Common Cytokine Receptor γ Chain and Interleukin 7 Receptor α Chain in Natural T Cell Development

1997 • 52 citations

A transgenic T cell receptor restores thymocyte differentiation in interleukin-7 receptor α chain-deficient mice

1997 • 51 citations

IL-7 supports the generation of cytotoxic T lymphocytes from thymocytes. Multiple lymphokines required for proliferation and cytotoxicity.

1990 • 49 citations

Effects of recombinant human IL-7 on blast cell proliferation in acute lymphoblastic leukemia.

1990 • 49 citations

Shared gamma(c) subunit within the human interleukin-7 receptor complex. A molecular basis for the pathogenesis of X-linked severe combined immunodeficiency.

1997 • 48 citations

Transduction of human melanoma cell lines with the human interleukin-7 gene using retroviral-mediated gene transfer: comparison of immunologic properties with interleukin-2

1993 • 46 citations

Studies on the role of IL-7 presentation by mesenchymal fibroblasts during early thymocyte development

2000 • 46 citations

Interleukin-7 Influences the Development of Thymic Dendritic Cells

1998 • 46 citations

Antitumor effects of interleukin-7 and adoptive immunotherapy on human colon carcinoma xenografts.

1993 • 46 citations

Reciprocal Cytokine-Mediated Cellular Interactions in Mouse Epidermis: Promotion of γ δ T-Cell Growth by IL-7 and TNFα and Inhibition of Keratinocyte Growth by γIFN

1993 • 46 citations

Interleukin 2-Independent Interleukin 7 Activity Enhances Cytotoxic Immune Response of HIV-1-Infected Individuals

1994 • 45 citations

Activation induced changes in expression and structure of the IL-7 receptor on human T cells

1992 • 45 citations

A novel regulatory myosin light chain gene distinguishes pre-B cell subsets and is IL-7 inducible.

1992 • 45 citations

Constitutive and IFN-gamma regulated expression of IL-7 and IL-15 in human renal cell cancer.

1999 • 45 citations

IL-7 in the cell-mediated immune response to a human pathogen.

1995 • 44 citations

Stromal cell-independent maturation of IL-7-responsive pro-B cells.

1998 • 44 citations

Cytokine production and heterogeneity of primary stromal cells that support B lymphopoiesis

1993 • 44 citations

Effect of MTP-PE liposomes and interleukin-7 on induction of antibody and cell-mediated immune responses to a recombinant HIV-envelope protein.

1994 • 43 citations

Interleukin-7 differentiates a subgroup of acute lymphoblastic leukemias

1991 • 41 citations

Cell cycle control of c-kit+IL-7R+ B precursor cells by two distinct signals derived from IL-7 receptor and c-kit in a fully defined medium.

1995 • 41 citations

Interleukin-7 enhances antimicrobial activity against Leishmania major in murine macrophages

1993 • 41 citations

Role of IL-7 in the shaping of the pulmonary gamma delta T cell repertoire.

1996 • 41 citations

Interleukin (IL)-7 Induces Rapid Activation of Pyk2, Which Is Bound to Janus Kinase 1 and IL-7Rα

2000 • 41 citations

Cytokine-mediated communication by keratinocytes and Langerhans cells with dendritic epidermal T cells

1996 • 40 citations

The growth factor IL-7 incuces expression of a transformation-associated antigen in normal pre-B cells

1990 • 40 citations

Regulation of HIV Production by Blood Mononuclear Cells from HIV-Infected Donors: I. Lack of Correlation Between HIV-1 Production and T Cell Activation

1993 • 40 citations

IFN-gamma abrogates IL-7-dependent proliferation in pre-B cells, coinciding with onset of apoptosis.

1994 • 39 citations

Apoptosis and interleukin 7 gene expression in chronic B-lymphocytic leukemia cells.

1995 • 39 citations

Down-Regulation of Murine Fibrosarcoma Transforming Growth Factor-beta1 Expression by Interleukin 7

1995 • 38 citations

Control of T Cell Development In Vivo by Subdomains Within the IL-7 Receptor α-Chain Cytoplasmic Tail

2001 • 38 citations

Variations in serum IL-7 and 90K/Mac-2 binding protein (Mac−2 BP) levels analysed in cohorts of HIV-1 patients and correlated with clinical changes following antiretroviral therapy

2001 • 38 citations

Identification of a novel low-affinity receptor for human interleukin-7

1992 • 37 citations

Specific T cell unresponsiveness in human filariasis: diversity in underlying mechanisms

1995 • 37 citations

Increased interleukin-7 levels in the sera of psoriatic patients: lack of correlations with interleukin-6 levels and disease intensity

2000 • 37 citations

Down-regulation of macrophage transforming growth factor-beta messenger RNA expression by IL-7.

1993 • 37 citations

Functional effect of IL-7-enhanced CD19 expression on human B cell precursors.

1993 • 37 citations

Signaling checkpoints during the development of T lymphocytes

1998 • 37 citations

IL 7-induced T cell receptor-gamma gene expression by pre-T cells in murine fetal liver cultures.

1992 • 35 citations

Bacterial invasion induces interleukin‐7 receptor expression in colonic epithelial cell line, T84

1997 • 34 citations

Control of chromatin accessibility for V(D)J recombination by interleukin-7

2001 • 34 citations

Interleukin-7 rescues human activated T lymphocytes from apoptosis induced by glucocorticoesteroids and regulates bcl-2 and CD25 expression

1995 • 34 citations

Cutting Edge: Identification of a Hybrid Cytokine Consisting of IL-7 and the β-Chain of the Hepatocyte Growth Factor/Scatter Factor

2001 • 33 citations

Synergism of interleukin 7 with the thymocyte growth factors interleukin 2, interleukin 6, and tumor necrosis factor α in the induction of thymocyte proliferation

1990 • 32 citations

Induction of primary anti‐viral cytotoxic T cells by in vitro stimulation with short synthetic peptide and interleukin‐7

1992 • 32 citations

γδ cells involved in contact sensitivity preferentially rearrange the Vγ3 region and require interleukin‐7

1997 • 32 citations

Interleukin-7 (IL-7) Induces Retinal Pigment Epithelial Cell MCP-1 and IL-8

1996 • 32 citations

EXPRESSION ANALYSIS AND CHARACTERIZATION OF ALTERNATIVELY SPLICED TRANSCRIPTS OF HUMAN IL-7Rα CHAIN ENCODING TWO TRUNCATED RECEPTOR PROTEINS IN RELAPSED CHILDHOOD ALL

2000 • 32 citations

Interleukin-7 receptor expression in cutaneous T-cell lymphomas

1996 • 32 citations

Status of kappa L chain gene rearrangements and c-kit and IL-7 receptor expression in stromal cell-dependent pre-B cells.

1992 • 32 citations

Disulfide Bond Assignment in Human Interleukin-7 by Matrix-assisted Laser Desorption/Ionization Mass Spectroscopy and Site-directed Cysteine to Serine Mutational Analysis

1997 • 31 citations

Hyperexpression of Interleukin-7 Is Not Necessary or Sufficient for Transformation of a Pre-B Lymphoid Cell Line

1991 • 30 citations

Interleukin-7—Dependent Interaction of Dendritic Epidermal T Cells with Keratinocytes

1995 • 30 citations

Effects of recombinant human cytokines on precursor-B acute lymphoblastic leukemia cells.

1991 • 29 citations

Characterization of a novel high affinity human IL-7 receptor. Expression on T cells and association with IL-7 driven proliferation.

1993 • 29 citations

TCR-gamma genes are rearranged but not transcribed in IL-7R alpha-deficient mice.

1997 • 28 citations

Inhibition of Interleukin 7 Receptor Signaling by Antigen Receptor Assembly

2000 • 28 citations

Interleukin‐7 in the skin of Schistosoma mansoni‐infected mice is associated with a decrease in interferon‐γ production and leads to an aggravation of the disease

1997 • 27 citations

A murine thymic stromal cell line which may support the differentiation of CD4−8− thymocytes into CD4+8− αβ T cell receptor positive T cells

1992 • 27 citations

CYTOKINE GENE EXPRESSION IN MURINE FETAL INTESTINE: POTENTIAL FOR EXTRATHYMIC T CELL DEVELOPMENT

1998 • 27 citations

Cytokine-independent Jak3 Activation upon T Cell Receptor (TCR) Stimulation through Direct Association of Jak3 and the TCR Complex

2001 • 27 citations

Interleukin-7 inhibits apoptosis of mouse malignant T-lymphoma cells by both suppressing the CPP32-like protease activation and inducing the Bcl-2 expression.

1996 • 27 citations

Interleukin 7 enhances the proliferation and effector function of tumor‐infiltrating lymphocytes from renal‐cell carcinoma

1993 • 26 citations

In vitro tracking of IL-7 responsiveness and gene expression during commitment of bipotent B-cell/macrophage progenitors

1996 • 26 citations

Interleukin‐7. Biology and implications for dermatology

1996 • 25 citations

Interleukin-7 gene transfer in non-small-cell lung cancer decreases tumor proliferation, modifies cell surface molecule expression, and enhances antitumor reactivity.

1996 • 25 citations

Human intestinal V delta 1+ T cells obtained from patients with colon cancer respond exclusively to SEB but not to SEA.

1995 • 25 citations

Extensive Alternative Splicing of Interleukin-7 in Malignant Hematopoietic Cells: Implication of Distinct Isoforms in Modulating IL-7 Activity

1999 • 25 citations

Interleukins 7 and 12 are expressed in head and neck squamous cancer

2001 • 24 citations

The interleukin-7 receptor gene is at 5pl3

1992 • 24 citations

A critical role for IL-7R signaling in the development of Helicobacter felis–induced gastritis in mice

2001 • 24 citations

Interleukin-7 mediates the generation and expansion of murine allosensitized and antitumor CTL

1992 • 24 citations

The effects of interleukin 7 (IL-7) on human bone marrow in vitro.

1991 • 23 citations

Use of Interleukin-7, Interleukin-2, and Interferon-γ to Propagate CD4+ T Cells in Culture with Maintained Antigen Specificity

1993 • 22 citations

Comparison of the 3D models of four different human IL-7 isoforms with human and murine IL-7

1998 • 22 citations

Comparative model building of interleukin‐7 using interleukin‐4 as a template: A structural hypothesis that displays atypical surface chemistry in helix D important for receptor activation

2000 • 22 citations

Identification of an IL-7-Associated Pre-Pro-B Cell Growth-Stimulating Factor (PPBSF). II. PPBSF Is a Covalently Linked Heterodimer of IL-7 and aMr 30,000 Cofactor

1998 • 21 citations

A Comparison of Proliferative Response to IL-7 and Expression of IL-7 Receptors in Intermediate TCR Cells of the Liver, Spleen, and Thymus

1996 • 21 citations

Identification of an IL-7-Associated Pre-Pro-B Cell Growth-Stimulating Factor (PPBSF). I. Production of the Non-IL-7 Component by Bone Marrow Stromal Cells from IL-7 Gene-Deleted Mice

1998 • 20 citations

The supportive effects of IL-7 on eosinophil progenitors from human bone marrow cells can be blocked by anti-IL-5.

1992 • 20 citations

Stimulation of B-cell lymphopoiesis by interleukin-7 leads to aggravation of murine leishmaniasis.

1995 • 20 citations

ER-MP12 antigen, a new cell surface marker on mouse bone marrow cells with thymus-repopulating ability: II. Thymus-homing ability and phenotypic characterization of ER-MP12-positive bone marrow cells

1993 • 19 citations

Changes in eosinophil and leukocyte infiltration and expression of IL-6 and IL-7 messenger RNA in mite allergen patch test reactions in atopic dermatitis

1996 • 18 citations

Gastrointestinal Cells of IL-7 Receptor Null Mice Exhibit Increased Sensitivity to Irradiation

2001 • 18 citations

EXOGENOUS INTERLEUKIN 7 AS A PROLIFERATIVE STIMULANT OF EARLY PRECURSOR B CELLS IN MOUSE BONE MARROW: EFFICACY OF IL-7 INJECTION, IL-7 INFUSION AND IL-7–ANTI-IL-7 ANTIBODY COMPLEXES

1998 • 17 citations

Multiple cytokine secretion by IL-7-stimulated human T cells

1992 • 17 citations

Interleukin 7 stimulates growth of fetal thymic precursors of cytolytic cells: induction of effector function by interleukin 2 and inhibition by interleukin 4

1990 • 17 citations

Mucosal IL-7-mediated immune responses in chronic colitis-IL-7 transgenic mouse model

1999 • 17 citations

Naive CD4⁺ T Cells Can be Sensitized with IL‐7

2001 • 15 citations

Growth inhibitory and agonistic signals of interleukin-7 (IL-7) can be mediated through the CDw127 IL-7 receptor

1994 • 15 citations

Interleukin-7 (IL-7)-induced proliferation of CD8+ T-chronic lymphocytic leukemia cells

1992 • 13 citations

Cultured Murine Dermal Cells Can Function Like Thymic Nurse Cells

1994 • 13 citations

IL-7 mRNA is not overexpressed in mycosis fungoides and pleomorphic T-cell lymphoma and is unlikely to be an autocrine growth factor in vivo

1996 • 13 citations

Cloning and expression of a cDNA encoding ovine interleukin 7

1995 • 13 citations

T-Cell Reconstitution by Molecular, Phenotypic, and Functional Analysis in the Thymus, Bone Marrow, Spleen, and Blood Following Split-Dose Polychemotherapy and Therapeutic Activity for Metastatic Breast Cancer in Mice

1993 • 13 citations

Influence of recombinant human interleukin (IL)‐7 on disease progression in mice infected with friend virus complex

1992 • 13 citations

Intestinal Epithelial Cell Line Induction of T Cell Differentiation from Bone Marrow Precursors

1996 • 12 citations

Interleukin-7 Induces Anti-Mycobacterium avium Activity in Human Monocyte Derived Macrophages

1996 • 12 citations

IL-7 Induces Surface Expression of B7/BB1 on Pre-B Cells and an Associated Increase in Their Costimulatory Effects on T Cell Proliferation

1994 • 11 citations

Characterization and Differentiation of an Early Murine Yolk Sac-Derived IL-7-Independent Pre-Pro-B Cell Line

1998 • 11 citations

Presence of CD8α‐CD8β‐positive TcR γ/δ thymocytes in the fetal murine thymus and their in vitro expansion with interleukin‐7

1992 • 11 citations

Development of a continuous IL-7-dependent murine pre-B cell line PB-1 suitable for the biological characterisation and assay of human IL-7

2000 • 10 citations

Consequences of Stable Transduction and Antigen-Inducible Expression of the Human Interleukin-7 Gene on Tetanus-Toxoid-Specific T Cells

1994 • 9 citations

A Selective Culture System for Generating TerminalDeoxynucleotidyl Transferase‐Positive Lymphoid Cells In Vitro. V. Detection of Stage‐Specific Pro‐B‐CellStimulating Activity in Medium Conditioned by Mouse Bone Marrow Stromal Cells

1993 • 8 citations

Immunomodulatory Effects of II-7 On Dengue Virus-Specific Cytotoxic Cd4+ T Cell Clones

1996 • 7 citations

Interleukin-7 Modulates Intracytoplasmatic CD23 Production and Induces Adhesion Molecule Expression and Adhesiveness in Activated CD4+CD23+T Cell Subsets

1996 • 7 citations

Localization of the human gene for Src-related protein tyrosine kinase LYN to chromosome 8q11-12: a lymphoid signaling cluster?

1994 • 7 citations

Introduction: B-1 cells: origins and functions

1996 • 6 citations

Sequence of bovine interleukin 7

1992 • 6 citations

IL-7 upregulates T cell receptor/CD3 expression by cultured dendritic epidermal T cells

1996 • 5 citations

cDNA cloning and expression of swine IL-7 from neonatal intestinal epithelium

2001 • 5 citations