Differential roles of stromal cells, interleukin-7, and kit-ligand in the regulation of B lymphopoiesis

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1985 • 2,145 citations

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow.

1991 • 1,622 citations

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

1990 • 1,448 citations

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

1988 • 1,390 citations

SRα Promoter: an Efficient and Versatile Mammalian cDNA Expression System Composed of the Simian Virus 40 Early Promoter and the R-U5 Segment of Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat

1988 • 1,351 citations

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

1988 • 1,336 citations

"Panning" for lymphocytes: a method for cell selection.

1978 • 1,319 citations

The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus

1990 • 1,208 citations

Identification of a ligand for the c-kit proto-oncogene

1990 • 970 citations

Stimulation of B-cell progenitors by cloned murine interleukin-7

1988 • 826 citations

Long-term culture of B lymphocytes and their precursors from murine bone marrow.

1982 • 612 citations

Regulation of Hemopoiesis by Bone Marrow Stromal Cells and Their Products

1990 • 546 citations

B cell precursor growth-promoting activity. Purification and characterization of a growth factor active on lymphocyte precursors.

1988 • 379 citations

A stromal cell line from myeloid long-term bone marrow cultures can support myelopoiesis and B lymphopoiesis.

1987 • 345 citations

Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen reactive B cells in vitro and in vivo.

1991 • 335 citations

Isolation of two early B lymphocyte progenitors from mouse marrow: A committed Pre-Pre-B cell and a clonogenic Thy-1lo hematopoietic stem cell

1986 • 330 citations

The ultrastructure of the hemopoietic environment of the marrow: a review.

1981 • 308 citations

Antigens displayed on murine B lymphocyte precursors.

1981 • 299 citations

Bone marrow stromal cell lines with lymphopoietic activity express high levels of a pre-B neoplasia-associated molecule

1987 • 254 citations

Recombinant interleukin 7, pre-B cell growth factor, has costimulatory activity on purified mature T cells.

1989 • 230 citations

Normal B cell precursors responsive to recombinant murine IL-7 and inhibition of IL-7 activity by transforming growth factor-beta.

1989 • 229 citations

The role of recombinant stem cell factor in early B cell development. Synergistic interaction with IL-7.

1991 • 222 citations

Interleukin 7 production and function in stromal cell-dependent B cell development.

1989 • 221 citations

A single bone marrow-derived stromal cell type supports the in vitro growth of early lymphoid and myeloid cells

1987 • 207 citations

Interleukin 7 is a T-cell growth factor.

1989 • 206 citations

B lymphopoiesis on stromal cell clone: stromal cell clones acting on different stages of B cell differentiation^*

1988 • 181 citations

Stromal cell lines which support lymphocyte growth: characterization, sensitivity to radiation and responsiveness to growth factors

1988 • 158 citations

Murine thymocytes proliferate in direct response to interleukin-7

1989 • 157 citations

Experimental Models for Understanding B Lymphocyte Formation

1987 • 132 citations

Myelogenous production and maturation of B lymphocytes in the mouse.

1981 • 126 citations

IL-7 induces human lymphokine-activated killer cell activity and is regulated by IL-4.

1991 • 82 citations

Phenotypic and functional characterization of murine B lymphocyte precursors isolated from fetal and adult tissues.

1983 • 76 citations

Stromal cells in myeloid and lymphoid long-term bone marrow cultures can support multiple hemopoietic lineages and modulate their production of hemopoietic growth factors

1986 • 75 citations

Pre-B cell generation potentiated by soluble factors from a bone marrow stromal cell line.

1988 • 74 citations

Cellular interactions affecting the maturation of murine B lymphocyte precursors in vitro.

1981 • 71 citations

Bone marrow stromal cell regulation of B lymphopoiesis: interleukin-1 (IL-1) and IL-4 regulate stromal cell support of pre-B cell production in vitro

1990 • 43 citations

A sensitive technique to monitor gene transfer and expression in bone marrow stem cells.

1989 • 14 citations

Putative B lymphocyte lineage precursor cells in early murine embryos

1984 • 12 citations

A colony assay system that detects B cell progenitors in fresh and cultured bone marrow

1989 • 8 citations