Alterations in T cell receptor and signal transduction molecules in melanoma patients.

Alterations in Signal Transduction Molecules in T Lymphocytes from Tumor-Bearing Mice

1992 • 650 citations

Impaired in Vitro Lymphocyte Transformation in Hodgkin's Disease

1965 • 379 citations

Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1.

1991 • 351 citations

Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma.

1993 • 344 citations

Functional properties of tumor-infiltrating and blood lymphocytes in patients with solid tumors: effects of tumor cells and their supernatants on proliferative responses of lymphocytes.

1986 • 319 citations

Cell Surface Molecules and Early Events Involved in Human T Lymphocyte Activation

1987 • 297 citations

Clonal anergy is induced in vitro by T cell receptor occupancy in the absence of proliferation.

1991 • 255 citations

Generation and decay of the immune response to a progressive fibrosarcoma. I. Ly-1+2- suppressor T cells down-regulate the generation of Ly-1-2+ effector T cells.

1984 • 249 citations

Delayed hypersensitivity in Hodgkin's disease

1972 • 244 citations

The Suppressor-Cell Network in Cancer

1978 • 172 citations

Sequential studies on cell‐mediated tumor immunity and blocking serum activity in ten patients with malignant melanoma

1973 • 148 citations

Persistent Immunologic Abnormalities in Long-Term Survivors of Advanced Hodgkin's Disease

1980 • 131 citations

Tumor-reactive T-cells accumulate in lung cancer tissues but fail to respond due to tumor cell-derived factor.

1992 • 117 citations

Immunoregulation in cancer-bearing hosts. Down-regulation of gene expression and cytotoxic function in CD8+ T cells.

1992 • 92 citations

Anergic Th1 cells express altered levels of the protein tyrosine kinases p56lck and p59fyn.

1992 • 89 citations

Alterations in NF kappa B/Rel family proteins in splenic T-cells from tumor-bearing mice and reversal following therapy.

1994 • 70 citations

Splenic Macrophages From Tumor-Bearing Mice Co-Expressing MAC-1 and MAC-2 Antigens Exert Immunoregulatory Functions Via Two Distinct Mechanisms

1991 • 69 citations

Immunoregulatory factors derived from human tumors. II. Partial purification and further immunobiochemical characterization of a human sarcoma-derived immunosuppressive factor expressing HLA-DR and immunoglobulin-related determinants.

1983 • 45 citations

Significance of Suppressor Macrophages for Immunosurveillance of Tumor-Bearing Mice<xref ref-type="fn" rid="FN2">2</xref>

1987 • 43 citations

Depressed Ability of Patients with Melanoma or Renal Cell Carcinoma to Generate Adherent Lymphokine-Activated Killer Cells

1991 • 26 citations

Suppressive Effects of Visceral Tumor on the Generation of Antitumor T Cells for Adoptive Immunotherapy

1991 • 25 citations

IL-2 secretion and T cell clonal anergy are induced by distinct biochemical pathways.

1991 • 21 citations

Cytokines and suppressor macrophages cause tumor-bearing host CD8+ T cells to suppress recognition of allogeneic and syngeneic MHC class II molecules

1992 • 16 citations

EL‐4 metastases in spleen and bone marrow suppress the nk activity generated in these organs

1987 • 11 citations

Characterization of FcεRIγ in human natural killer cells

1992 • 6 citations