Interleukin-7 or Interleukin-15 Enhances Survival ofMycobacterium tuberculosis-Infected Mice

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection.

1993 • 2,410 citations

Tumor necrosis factor-α is required in the protective immune response against mycobacterium tuberculosis in mice

1995 • 1,643 citations

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

1995 • 1,447 citations

Cloning of a T Cell Growth Factor that Interacts with the β Chain of the Interleukin-2 Receptor

1994 • 1,423 citations

Potent and Selective Stimulation of Memory-Phenotype CD8+ T Cells In Vivo by IL-15

1998 • 1,262 citations

Recognition of a lipid antigen by CD1-restricted αβ+ T cells

1994 • 976 citations

Natural and synthetic non-peptide antigens recognized by human γδ T cells

1995 • 974 citations

Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection.

1992 • 771 citations

CD1-Restricted T Cell Recognition of Microbial Lipoglycan Antigens

1995 • 751 citations

Interleukin 12 (IL-12) Is Crucial to the Development of Protective Immunity in Mice Intravenously Infected with Mycobacterium tuberculosis

1997 • 696 citations

CDlb restricts the response of human CD4−8−T lymphocytes to a microbial antigen

1992 • 577 citations

Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritis

1997 • 513 citations

Distinction of virgin and memory T lymphocytes. Stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation.

1987 • 505 citations

The role of interleukin–15 in T–cell migration and activation in rheumatoid arthritis

1996 • 492 citations

Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation

1995 • 372 citations

Interleukin-15 protects from lethal apoptosis in vivo

1997 • 339 citations

Induction and regulation of IL-15 expression in murine macrophages.

1996 • 327 citations

IL-12 increases resistance of BALB/c mice to Mycobacterium tuberculosis infection.

1995 • 325 citations

Activation of tuberculostatic macrophage functions by gamma interferon, interleukin-4, and tumor necrosis factor

1990 • 253 citations

In vivo cytokine gene expression in T cell subsets of the autoimmune MRL/Mp‐lpr/lpr mouse

1990 • 219 citations

CD1c restricts responses of mycobacteria-specific T cells. Evidence for antigen presentation by a second member of the human CD1 family.

1996 • 212 citations

The role of TNF-alpha in T-cell-mediated inflammation depends on the Th1/Th2 cytokine balance.

1994 • 205 citations

Interleukin 7 induces cytokine secretion and tumoricidal activity by human peripheral blood monocytes.

1991 • 187 citations

CD4+ alpha beta T cell and gamma delta T cell responses to Mycobacterium tuberculosis. Similarities and differences in Ag recognition, cytotoxic effector function, and cytokine production.

1995 • 184 citations

Characterization of Human CD8+ T Cells Reactive with Mycobacterium tuberculosis–infected Antigen-presenting Cells

1998 • 163 citations

Induction of murine peritoneal gamma/delta T cells and their role in resistance to bacterial infection.

1993 • 144 citations

Role of T Cell Subsets in Immunity against Intracellular Bacteria: Experimental Infections of Knock-Out Mice with Listeria monocytogenes and Mycobacterium bovis BCG

1994 • 127 citations

Keratinocyte-derived IL-7 serves as a growth factor for dendritic epidermal T cells in mice.

1993 • 126 citations

Functions and specificity of T cells following nucleic acid vaccination of mice against Mycobacterium tuberculosis infection.

1997 • 124 citations

IL-15, an immunomodulator of T cell responses in intracellular infection.

1997 • 120 citations

Interleukin 7 promotes long-term in vitro growth of antitumor cytotoxic T lymphocytes with immunotherapeutic efficacy in vivo.

1994 • 94 citations

Interleukin-15 Augments Superoxide Production and Microbicidal Activity of Human Monocytes againstCandida albicans

1998 • 75 citations

Protective Roles of γδ T Cells and Interleukin-15 inEscherichia coliInfection in Mice

1998 • 73 citations

Intercellular interactions and cytokine responsiveness of peritoneal alpha/beta and gamma/delta T cells from Listeria-infected mice: synergistic effects of interleukin 1 and 7 on gamma/delta T cells.

1993 • 63 citations

IL-15: the role of translational regulation in their expression

1996 • 62 citations

IL-7 stimulates protective immunity in mice against the intracellular pathogen, Toxoplasma gondii.

1995 • 54 citations

IL-7 in the cell-mediated immune response to a human pathogen.

1995 • 44 citations

Interleukin-7 enhances antimicrobial activity against Leishmania major in murine macrophages

1993 • 41 citations

In vitroproduction of tumour necrosis factor and prostaglandin E2 by peripheral blood mononuclear cells from tuberculosis patients

1990 • 38 citations

Three Distinct IL-2 Signaling Pathways Mediated by bcl-2, c-myc, and lck Cooperate in Hematopoietic Cell Proliferation.

1996 • 20 citations

Stimulation of B-cell lymphopoiesis by interleukin-7 leads to aggravation of murine leishmaniasis.

1995 • 20 citations

IL-2 and IL-7 differentially induce CD4-CD8- alpha beta TCR+NK1.1+ large granular lymphocytes and IL-4-producing cells from CD4-CD8- alpha beta TCR+NK1.1- cells: implications for the regulation of Th1- and Th2- type responses

1997 • 14 citations

Interleukin-7 Induces Anti-Mycobacterium avium Activity in Human Monocyte Derived Macrophages

1996 • 12 citations