Defective T-cell receptor γ gene rearrangement in interleukin-7 receptor knockout mice

RAG-1-deficient mice have no mature B and T lymphocytes

1992 • 2,859 citations

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1992 • 2,618 citations

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice.

1994 • 1,572 citations

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

1995 • 1,447 citations

Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain

1995 • 1,024 citations

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

1995 • 881 citations

Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population

1993 • 673 citations

T cell receptor δ gene mutant mice: Independent generation of αβ T cells and programmed rearrangements of γδ TCR genes

1993 • 528 citations

Developmental defects of lymphoid cells in Jak3 kinase-deficient mice

1995 • 493 citations

A thymic stromal cell line supports in vitro development of surface IgM+ B cells and produces a novel growth factor affecting B and T lineage cells.

1994 • 343 citations

CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus

1991 • 343 citations

Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation.

1994 • 334 citations

Interleukin 7 receptor-deficient mice lack gammadelta T cells.

1996 • 316 citations

T cell receptor β chain gene rearrangement and selection during thymocyte development in adult mice

1994 • 305 citations

Inhibition of gamma delta T cell development and early thymocyte maturation in IL-7 -/- mice.

1996 • 301 citations

ACCESSIBILITY CONTROL OF ANTIGEN-RECEPTOR VARIABLE-REGION GENE ASSEMBLY: Role ofcis-Acting Elements

1996 • 295 citations

Developmental potential of the earliest precursor cells from the adult mouse thymus.

1991 • 294 citations

Erythropoietin Induces Activation of Stat5 through Association with Specific Tyrosines on the Receptor That Are Not Required for a Mitogenic Response

1996 • 272 citations

Interleukin-7: a Cofactor For V(D)J Rearrangement of the T Cell Receptor β Gene

1993 • 221 citations

The interleukin-7 receptor alpha chain transmits distinct signals for proliferation and differentiation during B lymphopoiesis.

1996 • 213 citations

Interleukin-7 receptor alpha is essential for the development of gamma delta + T cells, but not natural killer cells.

1996 • 211 citations

Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development.

1996 • 179 citations

Effect of IL-7 on the growth of fetal thymocytes in culture.

1989 • 179 citations

T-cell lineage commitment and cytokine responses of thymic progenitors

1995 • 164 citations

Murine thymocytes proliferate in direct response to interleukin-7

1989 • 157 citations

The V–J Recombination of T Cell Receptor-γ Genes Is Blocked in Interleukin-7 Receptor–deficient Mice

1996 • 132 citations

Interleukin‐7 can induce the activation of Jak 1, Jak 3 and STAT 5 proteins in murine T cells

1995 • 127 citations

Cytokine production and requirements during T-cell development

1995 • 104 citations

Receptors and signals in early thymic selection

1995 • 90 citations

Interleukin 7-induced expression of specific T cell receptor gamma variable region genes in murine fetal liver cultures.

1993 • 69 citations

A transgenic T cell receptor restores thymocyte differentiation in interleukin-7 receptor α chain-deficient mice

1997 • 51 citations

Identification of a T-cell-specific transcriptional enhancer located 3' of C gamma 1 in the murine T-cell receptor gamma locus.

1991 • 51 citations

The role of c-Myb or a related factor in regulating the T cell receptor gamma gene enhancer.

1995 • 43 citations

Organization of the Murine T-Cell Receptor γ Locus

1993 • 35 citations

Junctional diversity in signal joints from T cell receptor beta and delta loci via terminal deoxynucleotidyl transferase and exonucleolytic activity.

1996 • 26 citations

Upregulation of T Cell Receptor γ Chain Transcription by Interleukin-2

1993 • 4 citations