Alterations in the signal‐transducing molecules of T cells and nk cells in colorectal tumor‐infiltrating, gut mucosal and peripheral lymphocytes: Correlation with the stage of the disease

The cytoplasmic domain of the T cell receptor ζ chain is sufficient to couple to receptor-associated signal transduction pathways

1991 • 782 citations

Alterations in Signal Transduction Molecules in T Lymphocytes from Tumor-Bearing Mice

1992 • 650 citations

T cell antigen receptor activation pathways: The tyrosine kinase connection

1991 • 442 citations

Requirement for association of p56lck with CD4 in antigen-specific signal transduction in T cells

1991 • 417 citations

Loss of T-cell receptor zeta chain and p56lck in T-cells infiltrating human renal cell carcinoma.

1993 • 385 citations

The T Cell Antigen Receptor: Insights into Organelle Biology

1990 • 361 citations

Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma.

1993 • 344 citations

Sequence requirements for induction of cytolysis by the T cell antigenFc receptor ζ chain

1992 • 333 citations

T-cell and basophil activation through the cytoplasmic tail of T-cell-receptor zeta family proteins.

1991 • 307 citations

The Biologic Roles of CD2, CD4, and CD8 in T-Cell Activation

1989 • 301 citations

Molecular Cloning of the Zeta Chain of the T Cell Antigen Receptor

1988 • 275 citations

Interleukin 2 activation of cytotoxic T-lymphocytes infiltrating into human metastatic melanomas.

1986 • 259 citations

Family of disulphide-linked dimers containing the ζ and η chains of the T-cell receptor and the γ chain of Fc receptors

1990 • 249 citations

T cell development in mice lacking the CD3-zeta/eta gene.

1993 • 235 citations

Abnormal T cell development in CD3-zeta-/- mutant mice and identification of a novel T cell population in the intestine.

1993 • 186 citations

Fc gamma receptor type III (CD16) is included in the zeta NK receptor complex expressed by human natural killer cells.

1990 • 169 citations

Disulfide linkage of the zeta and eta chains of the T cell receptor. Possible identification of two structural classes of receptors.

1988 • 146 citations

Tyrosine phosphorylation of the Fc gamma RIII(CD16): zeta complex in human natural killer cells. Induction by antibody-dependent cytotoxicity but not by natural killing.

1991 • 129 citations

Phenotypic analysis of tumor-infiltrating lymphocytes from human breast cancer.

1992 • 122 citations

CD5 antibodies increase intracellular ionized calcium concentration in T cells.

1987 • 92 citations

Biochemical identification of a direct physical interaction between the CD4: p56^lck and T_i(TcR)/CD3 complexes

1991 • 85 citations

Structural similarity between Fc receptors and T cell receptors. Expression of the gamma-subunit of Fc epsilon RI in human T cells, natural killer cells and thymocytes.

1991 • 76 citations

T cell receptor complexes containing Fc epsilon RI gamma homodimers in lieu of CD3 zeta and CD3 eta components: a novel isoform expressed on large granular lymphocytes.

1992 • 72 citations

Preferential usage of the Fc receptor gamma chain in the T cell antigen receptor complex by gamma/delta T cells localized in epithelia.

1994 • 69 citations

Monoclonal antibodies reactive with the T cell receptor zeta chain: production and characterization using a new method.

1989 • 60 citations

High Frequency of Cancer Patients with Abnormal Assembly of the T Cell Receptor‐CD3 Complex in Peripheral Blood T Lymphocytes

1994 • 52 citations

TCR isoform containing the Fc receptor γ chain exhibits structural and functional differences from isoform containing CD3ξ

1993 • 28 citations

Activated T-cell subsets in benign lymphoid hyperplasias and B-cell non-Hodgkin's lymphomas.

1991 • 16 citations

Immunological assays following exposure to halothane in clinical usage.

1991 • 14 citations