Identification of a ligand for the c-kit proto-oncogene

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Conditions controlling the proliferation of haemopoietic stem cells in vitro

1977 • 2,157 citations

Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

1987 • 1,627 citations

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

1985 • 1,590 citations

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

1988 • 1,390 citations

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

1988 • 1,336 citations

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1986 • 1,244 citations

Hereditary Anemias of the Mouse: A Review for Geneticists

1979 • 1,141 citations

Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation

1978 • 846 citations

Stimulation of B-cell progenitors by cloned murine interleukin-7

1988 • 826 citations

Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.

1988 • 727 citations

The murine interleukin-4 receptor: Molecular cloning and characterization of secreted and membrane bound forms

1989 • 645 citations

Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation

1978 • 634 citations

Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles

1990 • 632 citations

Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W.

1990 • 599 citations

Gene‐induced embryological modifications of primordial germ cells in the mouse

1957 • 556 citations

Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice.

1989 • 495 citations

B cell precursor growth-promoting activity. Purification and characterization of a growth factor active on lymphocyte precursors.

1988 • 379 citations

Decreased production of mast cells in S1/S1d anemic mice

1979 • 372 citations

W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c-kit receptor.

1990 • 349 citations

The Dominant W ⁴² Spotting Phenotype Results from a Missense Mutation in the c- kit Receptor Kinase

1990 • 287 citations

The Human Gene Encoding GM-CSF Is at 5q21-q32, the Chromosome Region Deleted in the 5q ^- Anomaly

1985 • 237 citations

Demonstration of epidermal growth factor-induced receptor dimerization in living cells using a chemical covalent cross-linking agent.

1988 • 228 citations

In vitro duplication and ‘cure’ of haemopoietic defects in genetically anaemic mice

1977 • 195 citations

Heterogeneity in Human Interleukin-3 Receptors

1989 • 153 citations

Characterization of the cell surface receptor for granulocyte-macrophage colony-stimulating factor.

1986 • 149 citations

Tissue transplantation as an analytic and therapeutic tool in hereditary anemias

1970 • 145 citations

An experimental analysis of the pigment defect caused by mutations at the W and Sl loci in mice

1968 • 139 citations

Characterization of the cell surface receptor for a multi-lineage colony-stimulating factor (CSF-2 alpha).

1986 • 122 citations

TWO HEREDITARY MOUSE ANEMIAS (Sl/Sl^d and W/W^v) DEFICIENT IN RESPONSE TO ERYTHROPOIETIN*

1968 • 98 citations

Proof of whole-cell implant in therapy of W-series anemia

1968 • 70 citations

Implantation of Normal Blood-Forming Tissue in Radiated Genetically Anemic Hosts

1956 • 66 citations

The Response of W/W^v and Sl/Sl^d Anaemic Mice to Haemopoietic Stimuli

1972 • 64 citations

T-cell growth factor P40 promotes the proliferation of myeloid cell lines and enhances erythroid burst formation by normal murine bone marrow cells in vitro

1990 • 59 citations

Giant granules of beige mice. A quantitative marker for granulocytes in bone marrow transplantation.

1973 • 59 citations

Stimulation of multipotential, erythroid and other murine haematopoietic progenitor cells by adherent cell lines in the absence of detectable multi-CSF (IL-3)

1985 • 58 citations

Studies on the Defective Haematopoietic Microenvironment of Sl/Sl^d Mice

1973 • 54 citations

Biochemical comparison of murine colony-stimulating factors secreted by a T cell lymphoma and a myelomonocytic leukemia.

1984 • 49 citations

A novel mast cell growth factor (MCGF-3) produced by marrow-adherent cells that synergizes with interleukin 3 and interleukin 4.

1990 • 45 citations

The roles of granulocyte-macrophage colony-stimulating factor and interleukin 3 in stromal cell-mediated hemopoiesis in vivo.

1988 • 44 citations

Identification of the hematopoietic growth factors elaborated by bone marrow stromal cells using antibody neutralization analysis.

1987 • 33 citations

Role of stromal populations in hemopoietic stem cell proliferation. I. Physically distinct subpopulations of hemopoietic stem cells and stromal progenitors determine long-term culture hemopoiesis.

1987 • 20 citations

The kinase activity of the v-fms encoded protein has a low pH optimum.

1989 • 5 citations